Clinical trials: sponsored by Fudan University
Colorectal Neoplasms, Colonoscopy
AI-assisted Integrated Care to Promote Colonoscopy Uptake
Colorectal cancer (CRC) ranks the second most common cancer and the fourth leading cause of cancer-related deaths in China. Early screening of CRC has been proven to reduce the incidence and mortality, with colonoscopy as the…
- Trial name
- NCT07261059
- Testing
- AI-assisted integrated care
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fudan University
CRBSI - Catheter Related Bloodstream Infection, Evidence-based Nursing Practice
Multicenter Clinical Translational Study of "ICU-NO CRBSI" Based on Improvement Science
The goal of this type of study is to construct the continuous quality promotion project "ICU-NO CRBSI(Catheter-Related Bloodstream Infection , CRBSI)" based on improvement science, and to verify its effect in the prevention of…
- Conditions
- CRBSI - Catheter Related Bloodstream Infection, Evidence-based Nursing Practice, Central Venous Catheter Related Bloodstream Infection, Central Venous Catheter Associated Bloodstream Infection
- Trial name
- NCT06085690
- Testing
- evidence-based intervention Plan for the Prevention of CRBSI in ICU patients
- Where
- China
- Volunteers
- 8,050 people, healthy volunteers welcome
- Sponsor
- Fudan University
Autism Spectrum Disorder, Early Developmental Impairment
Multicenter Validation Study on Autism Screening Using a Machine-assisted System
The goal of this observational study is to assess the effectiveness of a machine-assisted system for early screening of autism. The main questions it aims to answer are: Does the machine-assisted system including 5 main…
- Conditions
- Autism Spectrum Disorder, Early Developmental Impairment, Language Development Disorders
- Trial name
- NCT07006948
- Testing
- Autism Diagnostic Observation Schedule, the 2nd edition(ADOS-2), Griffiths Developmental Scales, Chinese edition(GDS-C)
- Where
- 10 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Cholestatic Liver Disease
Application and Effect Evaluation of Medium Chain Fatty Acid Rich Milk Powder in Infants With Cholestatic Liver Disease
To verify the effect of feeding milk powder rich in medium chain fatty acids on improving the nutritional status and disease status of infants with cholestatic liver disease and To evaluate the safety of feeding milk powder rich…
- Trial name
- NCT05922332
- Testing
- Rich medium chain fatty acid milk powder group, Regular milk powder group
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Diarrhea Infantile
Phenotype and Multi-omics Analysis of Children With Congenital Diarrhea and Enteropathy in China
This study will establish a clinical cohort of children with congenital diarrhea and enteropathy (CODE), mine biomarkers of CODE through multi-omics technology and construct a clinical risk prediction model.
- Trial name
- NCT06356545
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Platelet Function and Thrombus Formation
Zhongshan Ketogenic Diet Study 1
This dietary intervention study was designed to investigate the impact of a ketogenic diet on platelet function and and thrombus formation.
- Trial name
- NCT07117903
- Testing
- Normal diet + vehicle, Normal diet + aspirin, Ketogenic diet + vehicle
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Fudan University
Congenital Hearing Loss, Gene Therapy
Perceptual Evaluation and Rehabilitation System Development for Congenital Hearing Loss
This study aims to establish a novel multimodal evaluation and precision rehabilitation system for patients with congenital hearing loss who have received hearing aids, cochlear implantation, or emerging gene therapy.
- Conditions
- Congenital Hearing Loss, Gene Therapy, Speech Perception, Rehabilitation
- Trial name
- NCT07024524
- Testing
- Rehabilitation training
- Where
- China
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Eye & ENT Hospital of Fudan University
Kaposiform Hemangioendothelioma
The Effect of Sirolimus on Immunizations During the Treatment of Kaposiform Hemangioendothelioma
To research and explore the antibody protection and immune memory after vaccination in children with KHE during sirolimus administration.
- Trial name
- NCT05351216
- Where
- China
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Gastric (Stomach) Cancer
Fecal DNA Methylation and Helicobacter Pylori Gastric Cancer Susceptibility Genes Test
This is a multicenter, cross-sectional study. It is based on fecal methylation site detection, H. pylori susceptibility testing of fecal samples, and a combination of the two, compared with the "gold standard" imaging tests, CT…
- Trial name
- NCT06943768
- Testing
- fecal methylation site-based testing and fecal Helicobacter pylori gastric cancer susceptibility gene-based testing
- Volunteers
- 9,654 people, healthy volunteers welcome
- Sponsor
- Fudan University
Toric Intraocular Lens Stability, Visual Quality
Toric Intraocular Lens (IOL) Implantation for Management of Cataracts
This study included cataract patients who underwent toric intraocular lens (IOL) implantation, which aimed to evaluate the stability and clinical visual quality of toric IOLs.
- Trial name
- NCT05797298
- Where
- 2 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Eye & ENT Hospital of Fudan University
Lung Injury, Acute
Lung Atelectasis Improvement Through Positive End Expiratory Pressure During Anesthetic Induction
Anesthetic induction could lead to lung atelectasis, increase intrapulmonary shunt, and potentially impair oxygenation. The study aimed to validate that a positive end-expiratory pressure (PEEP) of 10 cmH2O could reduce lung…
- Trial name
- NCT06900426
- Testing
- 10 PEEP, ZEEP, 5PEEP
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fudan University
Autism Spectrum Disorder, Healthy
Differences in Prosocial Behaviors and Related Brain Networks in Children With Autism and Typical Development
The goal of this observational study is to compare the brain functional network between children with autism and typical development, using magnetic resonance imaging (MRI), electroencephalogram/event-related potentials(EEG/ERPs)…
- Trial name
- NCT06908174
- Testing
- ADOS-2
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Infants
Application Evaluation of Newborn Home Skin Care Management System Under the Service of "WeChat Platform+Health Care"
Through the establishment of the newborn home skin care management system under the service of "WeChat platform+health care", the investigators focus on the common skin problems of newborns at home, push health education…
- Trial name
- NCT06544096
- Testing
- intervention group (WeChat platform + healthcare), control group (routine health education)
- Where
- China
- Volunteers
- 692 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Pediatrics, Critical Illness
Construction and Application of the Visualization Training Platform Based on a Multimodal Standardized Dataset for Pain Assessment in Critically Ill Children
The goal of this clinical trial is to learn if the visualization training platform based on a multimodal standardized dataset for pain assessment in critically ill children is applicable for pain assessment training.
- Conditions
- Pediatrics, Critical Illness, Pain Measurement
- Trial name
- NCT06431802
- Testing
- Conventional intervention, Platform intervention
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Lung Function
Acute Effects of Low Temperature Exposure on Respiratory System
This is a randomized controlled human exposure crossover study. Investigators aims to assess the acute effects of low-temperature exposure on respiratory health and the underlying mechanisms.
- Trial name
- NCT06652932
- Testing
- Low temperature (15°C) group, Moderate temperature (22°C) group
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fudan University
Cognitive Function
Acute Effects of Cold Exposure on Cognitive Function
This is a randomized controlled human exposure crossover study. Investigators aims to assess the acute effects of low-temperature exposure on cognitive function and the underlying mechanisms.
- Trial name
- NCT06654167
- Testing
- Low temperature (15℃) group, Moderate temperature (22℃) group
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fudan University
Cardiovascular System
Acute Effects of Cold Exposure on Cardiovascular System
This is a randomized controlled human exposure crossover study. Investigators aim to assess the acute effects of low temperature exposure on cardiovascular system and the underlying mechanisms.
- Trial name
- NCT06652425
- Testing
- Low temperature (15°C) group, Moderate temperature (22°C) group
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fudan University
Altitude Hypoxia, Neonatal Encephalopathy
Neonatal Electrical Activity at Different Altitude Levels
In this study, the objective is to compare neonatal cerebral electrical activity within 3 days after birth across different altitude areas using amplitude-integrated electroencephalography (aEEG), and establish reference value…
- Trial name
- NCT05966714
- Testing
- aEEG
- Where
- 2 sites in China
- Volunteers
- 531 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Steroid-Sensitive Nephrotic Syndrome
Rituximab in the First Episode of Paediatric Nephrotic Syndrome
The study will be a randomized, open-label trial in children with the initial episode of SSNS and whose state of complete remission after received standard prednisolone, to determine whether rituximab (a single intravenous…
- Trial name
- NCT05850546
- Testing
- Rituximab, Corticosteroid
- Where
- 3 sites in China
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Implementation Science, Transportation of Patients
Implementation Study of Intra-hospital Transfer of Pediatric Inpatients
This study implemented the "Clinical Practice Guidelines for In-hospital Transfer of Pediatric Inpatients (2023 edition)" released by the research team in June 2023 in real clinical settings.
- Trial name
- NCT06512805
- Testing
- Routine transport, Post-guideline transfer
- Where
- China
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University