Clinical trials: sponsored by Kaiser Permanente
Sedentary Behavior, Physical Inactivity
Promoting Physical Activity in Older Hispanic/Latino(a) Adults
In this randomized controlled trial, study staff will randomize 130 Hispanic/Latino adults without dementia and over age 55 from Southern California and from Kaiser Permanente Washington (State) to either the culturally adapted…
- Conditions
- Sedentary Behavior, Physical Inactivity, Alzheimer Disease, Protection Against
- Trial name
- NCT06362824
- Testing
- De Pie Intervention, Active Comparison Group: Healthy Actions And Lifestyles To Avoid Dementia (HALT-AD)
- Where
- 2 sites in United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Covid-19 Vaccination
Effect of Messaging on Pragmatic Outcomes Within an Integrated Healthcare System
COVID-19 vaccination among patients at high risk for severe disease has declined in the United States since 2022. Prior research, including discrete choice experiments (DCEs), has demonstrated that vaccine preferences are…
- Trial name
- EMPOWeR (NCT07838038)
- Testing
- Vaccine choice message, Vaccine choice + platform-framed message, Vaccine choice + HCP trust-framed message
- Where
- United States
- Volunteers
- 1,300,000 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
CKD - Chronic Kidney Disease
The Use of Risk Prediction to Identify Patients at Risk for Chronic Kidney Disease: Patient and Provider Interventions for Patients at High Risk for Chronic Kidney Disease
This prospective, cluster-randomized trial is structured as a pragmatic study, embedding the outreach intervention within routine clinical workflows. The intervention reflects real-world provider-patient communication methods.
- Trial name
- RISK (NCT07857200)
- Testing
- Letter Intervention, Letter + Phone Call Intervention:, Augmented usual care
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Diabetes Mellitus, Type 2
Randomized Pilot Trial of AYUDA Program for Younger Latinx Adults With Type 2 Diabetes
The study will evaluate the feasibility, acceptability, and effectiveness of AYUDA (Assisting Younger Adults with Diabetes), a 12-week culturally text message program for Latinx adults newly diagnosed with type 2 diabetes who are…
- Trial name
- AYUDA (NCT07019649)
- Testing
- AYUDA Program
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Postoperative Pain, Preoperative Anxiety
Aromatherapy and Its Impact on Preoperative Anxiety, Postoperative Pain, and Patient Experience
Aromatherapy's Impact on Preoperative Anxiety, Postoperative Pain, and Patient Experience Introduction: Surgery often results in increased levels of anxiety and postoperative pain.
- Conditions
- Postoperative Pain, Preoperative Anxiety, Patient Experience
- Trial name
- NCT07771205
- Testing
- Aromatherapy, Unscented Pod
- Where
- United States
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Cardiovascular Diseases, Health Care Utilization
Structural Conditions and Health After Release From Prison
People released from prison experience two times higher cardiovascular (CV) mortality than the general population, have a high prevalence of poor CV health and increased risk of CV events within 2 years of release.
- Trial name
- SCHARP (NCT05989282)
- Where
- United States
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Type 2 Diabetes, PreDiabetes
Recreational Basketball to Increase Participation in Diabetes Prevention
The purpose of this study is to assess the efficacy of adapting the National Diabetes Prevention Program (NDPP) to include recreational sports in effort to increase physical activity (PA) and promote lifestyle changes that can…
- Trial name
- DPPHoops (NCT05066542)
- Testing
- NDPP + Basketball (BB), NDPP Standard of Care SOC
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Bariatric Surgery Candidate, Severe Obesity
Single Anastomosis Duodenal Ileal Bypass (SADI) for Sleeve Revision
The goal of this study is two part: 1) to add to the literature which is still somewhat sparse with numbers of patients undergoing the Single Anastomosis Duodenal Ileal Bypass (SADI) as a revision for laparoscopic sleeve…
- Trial name
- SADI (NCT04165694)
- Testing
- Single Anastomosis Duodenal Ileal Bypass (SADI)
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Suicide Prevention, Suicide Risk | Patient
Pilot Testing Suicide Risk Prediction Algorithms in Primary Care
The goal of this pilot study is to learn whether the use of suicide risk prediction algorithms in primary care can help identify people who may benefit from extra mental health monitoring.
- Trial name
- NCT07068685
- Testing
- Suicide risk prediction algorithm
- Where
- United States
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Influenza, Community-acquired Pneumonia
Fluad vs. Fluzone High-Dose Vaccine Effectiveness Among Adults ≥65 Years
This study will evaluate the relative vaccine effectiveness of quadrivalent adjuvanted inactivated influenza vaccine (aIIV4) versus quadrivalent high-dose inactivated influenza vaccine (HD-IIV4) in preventing polymerase chain…
- Conditions
- Influenza, Community-acquired Pneumonia, Cardiovascular Events
- Trial name
- NCT06029933
- Testing
- Adjuvanted Quadrivalent Inactivated Influenza Vaccine (aIIV4), High-Dose Quadrivalent Inactivated Influenza Vaccine (HD-IIV4)
- Where
- United States
- Volunteers
- 1,500,000 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Obstructive Sleep Apnea (OSA)
Assessing the Validity of the PAP Problems Triage Tool in Patients With PAP Treatment for Obstructive Sleep Apnea
The intended use of the Positive Airway Pressure (PAP) Problems Triaging Tool (TT) is to appropriately triage patients with a PAP-associated problem(s) to a specific intervention(s) based on patient responses.
- Trial name
- TriagingTool (NCT05530967)
- Testing
- TT, VE
- Where
- United States
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Obstructive Sleep Apnea (OSA), Insomnia
Validating the Use of a Subjectively Reported Sleep Vital Sign
Sleep disorders are commonly under-recognized in the primary care setting and available screening tools are often are limited. The study inestigators hypothesize that the use of a novel subjective sleep vital sign (VS) will…
- Conditions
- Obstructive Sleep Apnea (OSA), Insomnia, Restless Leg Syndrome (RLS), Hypersomnia Type; Sleep Disorder
- Trial name
- SVS (NCT03018912)
- Testing
- Sleep VS
- Where
- United States
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
OSA, Heart Failure
Impact of Early Diagnosis and Treatment of OSA on Hospital Readmission in Hospitalized Cardiac Patients
The purpose of this study is to determine whether early diagnosis of obstructive sleep apnea and initiation of and adherence to CPAP therapy in hospitalized cardiac patients would impact 30-day hospital readmission rates.
- Conditions
- OSA, Heart Failure, Myocardial Infarction, Arrhythmia, Cardiac
- Trial name
- CV Readmit (NCT03647891)
- Testing
- Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Narcotic Use, Central Sleep Apnea
Diagnosis of Sleep-Related Respiratory Disorders in Patients With Narcotic Medications
The present study is a prospective, single cohort study involving patients on narcotic medications, undergoing overnight sleep studies in the clinical sleep laboratory.
- Trial name
- WP-NARC001 (NCT03670914)
- Testing
- WatchPAT 200
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Obstructive Sleep Apnea (OSA)
CPAP Population Management
The investigators propose a study to formally compare two Continuous Positive Airway Pressure (CPAP) follow-up pathways: 1) Usual care - follow-up visits reflect standard care practice and we rely on patients to reach out to us…
- Trial name
- NCT04559737
- Testing
- Case Management
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease
Impact of Early Diagnosis and Treatment of OSA on Hospital Readmission in Hospitalized COPD Patients
The purpose of this study is to determine whether early diagnosis of OSA and initiation of and adherence to CPAP therapy in patients hospitalized for chronic obstructive pulmonary disease reduce 30-day hospital readmission rates.
- Trial name
- COPD Readmit (NCT03647462)
- Testing
- Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Dementia, Alzheimer Disease
The Brain Health Study: A Pragmatic, Patient-Centered Trial
The eRADAR Brain Health Study seeks to refine and test a novel, low-cost strategy for increasing dementia detection within primary care.
- Trial name
- NCT05356702
- Testing
- Brain Health Assessment
- Where
- 5 sites in United States
- Volunteers
- 3,417 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Type 1 Diabetes
Expansion of the T1DES Pilot to a Public Hospital
Diabetes distress has been identified as one of the largest contributors to the racial disparity in glycemic control that disproportionately burdens Black patients ages 18-30 years with type 1 diabetes (T1D).
- Trial name
- NCT06494722
- Testing
- Diabetes Education, T1DES
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Depression, Anxiety
Filipino Family Health Initiative 1.0
The goal of this clinical trial is to test the effectiveness of an online parenting program on Filipino parents living in California.
- Conditions
- Depression, Anxiety, Parenting
- Trial name
- FFHI (NCT06569303)
- Testing
- Incredible Years® School Age Basic Parent Training Program, American Academy of Pediatrics, Bright Futures Handouts
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Diabetes Mellitus
ASCEND: ApproacheS to CHC ImplEmeNtation of SDH Data Collection and Action
This work will test a set of strategies for helping community health centers (CHCs) routinely identify and take action on the SDH-related needs of patients with / at risk for DM using a stakeholder-driven process to develop…
- Trial name
- ASCEND (NCT03607617)
- Testing
- SDH Tool
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente