Clinical trials: sponsored by Peking University Third Hospital
Fall Risk in Middle-Aged and Older Adults
Short-term Changes in Postural Sway, Gait, and fNIRS-derived Cortical Metrics After a 4-week AI-assisted Exercise Program: a Single-arm Pre-post Study
This single-arm pre-post study will enroll 50 participants aged 52-65 years who will undergo a 4-week AI-assisted exercise intervention.
- Trial name
- NCT07876011
- Testing
- AI-assited exercise
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Transgender, Gender Incongruence
China Gender-affirming Hormone Therapy Study
Data about transgender medical care, especially the gender-affirming hormone therapy (GAHT) is extremely insufficient in China. Few evidence exists in the physical and psychological effects of the hormonal treatment in Chinese…
- Trial name
- CGAHT (NCT05318755)
- Testing
- GAHT for transgender men, GAHT for transgender women
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Osteoporosis，Neurological Disorders
Beijing Osteoporosis With Neurological Disorders in Epigenetic Changes Study
Epigenetic modification refers to the change of heritable gene expression occurring in the case of unchanged DNA sequence, including DNA methylation, epigenetic modification, RNAS, chromatin modification, etc.
- Trial name
- BONE (NCT03401619)
- Testing
- Exercise，Nutrition，Bisphosphonates，Statins，Calcitonin,Vitamin D，et al.
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
ACL Injury
Motor Imagery-Enhanced Rehabilitation Modulates Cortical Plasticity and Functional Recovery After ACL Reconstruction
Part 1: Neural Correlates of Motor Imagery in ACLR Patients This cross-sectional study aims to systematically compare differences in electroencephalographic (EEG) activity between patients who have returned to sport one year…
- Trial name
- NCT07833189
- Testing
- Motor Imagery Therapy (i.e., "mentally practicing movement"), conventional rehabilitation"
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Clinical Decision-making
Large Language Model Assistance for Clinical Decision-Making Among Rural Physicians
This study will evaluate whether, relative to conventional information retrieval approaches, direct large language models (LLM) access and LLM use training can improve the overall clinical decision-making ability of rural…
- Trial name
- NCT07711600
- Testing
- LLM-Use Training, Conventional Non-LLM Resources, LLM Second-Opinion Review
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Partial Rotator Cuff Tears (PRCTs)
High-frequency Short-course Extracorporeal Shock Wave Therapy for Partial Rotator Cuff Tears: Study Protocol for a Multicenter, Randomized, Controlled Trial
This is a multicenter, randomized controlled clinical study exploring three different extracorporeal shock wave therapy (ESWT) regimens for patients with partial rotator cuff tears, a common cause of chronic shoulder pain and…
- Trial name
- NCT07673055
- Testing
- Arm 1 Intervention Name: High-frequency short-course extracorporeal shock wave therapy Arm 2 Intervention Name: High-frequency intensive extracorporeal shock wave therapy Arm 3 Intervention Name: Conv
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Antibiotic, Allergic Diseases
Probiotic Intervention on the Development of Allergic Diseases in Infants Exposed to Antibiotics Early in Life
Early antibiotic exposure is an important environmental factor that disrupts the establishment of the infant gut microbiota and leads to microbial dysbiosis.
- Conditions
- Antibiotic, Allergic Diseases, Infants, Probiotic
- Trial name
- NCT07532421
- Testing
- Probiotic mixture
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Diabetic Foot Disease, Diabete Mellitus
Detection of Diabetic Foot Skin Damage Using Plantar Mechanical Parameters
Diabetes represents one of the major chronic diseases, with diabetic ulcers being a significant adverse prognosis. Approximately 80% of lower limb amputations are attributed to diabetic foot ulcers, which constitute a primary…
- Conditions
- Diabetic Foot Disease, Diabete Mellitus, Mechanical Factor
- Trial name
- NCT07470255
- Testing
- Detection of the elastic modulus of the plantar skin
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Patellar Tendinopathy
Bilateral Lower Limb Biomechanics During Side-Cutting in Unilateral Patellar Tendinopathy
Patellar tendinopathy (PT) is a common overuse injury in sports that involve jumping and directional changes. The biomechanical differences between individuals with PT and healthy controls during side-cutting, as well as whether…
- Trial name
- NCT07463560
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Injuries
Neuromuscular Rehab for ACL Reconstruction: Knee Function & Brain Plasticity
This study focuses on patients with anterior cruciate ligament (ACL) rupture and reconstruction, aiming to systematically investigate the clinical efficacy and underlying mechanisms of neuromuscular training in restoring knee…
- Trial name
- NCT07243860
- Testing
- Neuromuscular Training, Conventional Rehabilitation
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Central Compartment Atopic Disease (CCAD)
Development of A Multi-section Olfactory Cleft Opacity Staging System in Patients With CCAD
This study aims to develop a modified CT scoring system to evaluate the association between olfactory cleft obstruction patterns and olfactory dysfunction in patients with central region atopic disease (CCAD).
- Trial name
- NCT07380945
- Testing
- Computer Tomography
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Hemodynamically Significant Patent Ductus Arteriosus
Research on the Individualized Treatment Strategy for Extremely Preterm Infants With hsPDA Based on Biomarkers and Targeted Delivery Systems
This project aims to address the need for individualized precision therapy for hemodynamically significant patent ductus arteriosus (hsPDA) in extremely preterm infants by integrating clinical biomarker screening with the design…
- Trial name
- BTDS-IT-hsPDA- (NCT07374146)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Injuries
Effect of Visual-Guided Balance Training on Knee Motor Function and Biomechanical Characteristics After ACL Reconstruction
This study aims to investigate the improvement effect of visual-guided balance training on the knee joint function and gait performance of patients after ACLR, and to clarify the advantages of this training program compared to…
- Trial name
- NCT07306221
- Testing
- Traditional group, Intervention Group
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Injuries
The Effect of Single-leg 20-degree Squats Combined With Conventional Training on the Biomechanical Characteristics of Gait After Anterior Cruciate Ligament Reconstruction Surgery
Anterior cruciate ligament (ACL) tears are one of the most common sports injuries, with an ACL injury rate as high as 20.9% in the general population .
- Trial name
- NCT07308431
- Testing
- single-leg 20° squat training, regular training
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Patellar Tendinopathy / Jumpers Knee, Kinesio Taping
Effects of Kinesio Taping on Gait Biomechanics in Patellar Tendinopathy Patients
This study employed two distinct Kinesio Taping (KT) methods to treat patients with Patellar Tendinopathy (PT). It aimed to compare the efficacy between combined KT-EDF (Epidermis-Dermis-Fascia, EDF) with KT-I taping (I Strip…
- Trial name
- NCT07143942
- Testing
- Kinesio Taping, exercise therapy
- Where
- China
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Infertility, Chromosome Abnormality
Embryo Selection by Noninvasive Preimplantation Genetic Test
The objective of this study is to explore whether non-invasive chromosome screening (NICS) can be used as an effective indicator for embryos selection besides morphology through a multicenter randomized controlled trial, by…
- Trial name
- ESNi-PGT (NCT04339166)
- Testing
- Non-invasive chromosome screening（NICS）
- Where
- 13 sites in China
- Volunteers
- 1,152 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Alzheimer's Disease，Mild Cognitive Impairment
Cohort Study on Cognitive Decline in Elderly
Alzheimer's Disease (AD) prevention and control currently face severe challenges, with limited treatment options and effectiveness available. Once the disease progresses to the AD stage, it is essentially irreversible.
- Trial name
- NCT07093892
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Ageing
Exploratory Study on the Role of Vitamin C in Promoting Health in Middle-Aged and Elderly Adults
The purpose of this clinical trial is to understand whether oral vitamin C can help delay the aging of middle-aged and elderly individuals, search for sensitive biomarkers of human aging, and provide new paradigms and scientific…
- Trial name
- VitC-Aging (NCT06794255)
- Testing
- Vitamin C
- Where
- 3 sites in China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Polycystic Ovary Syndrome (PCOS)
A Randomized Controlled Trial of Acupuncture for Insulin Resistance in Patients With Polycystic Ovary Syndrome
To determine the efficacy and safety of 2 different treatment modalities: 1) acupuncture plus lifestyle management (treatment group), 2) placebo plus lifestyle management (control group) in the treatment of insulin resistance in…
- Trial name
- NCT06306417
- Testing
- lifestyle intervention, acupuncture
- Where
- China
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Elderly (People Aged 65 or More), Home Environment Related Disease
Assessing the Performance of GPT-4o in Evaluating the Safety of Home Environment for Older Adults
This study is an investigative study, taking the elderly in Beijing community as an example, and taking photos of different areas in the home environment of the elderly who agree to participate in the study (a total of seven…
- Trial name
- NCT06962696
- Testing
- No intervention
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital