Clinical trials: sponsored by Semmelweis University
Anxiety, Hospitalization
Virtual Nature Versus Guided Imagery for Anxiety and Well-Being in Hospitalized Older Adults
Long hospital stays can be difficult for older adults. Being confined to a ward, with limited mobility and little access to the outdoors, may contribute to anxiety, low mood, and reduced well-being.
- Conditions
- Anxiety, Hospitalization, Quality of Life, Psychological Distress
- Trial name
- NCT07765355
- Testing
- Immersive virtual reality nature exposure, Guided imagery
- Where
- 2 sites in Hungary
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Neurodevelopmental Disorder (Diagnosis)
Virtual Reality Headset as an Alternative Tool for Reducing Dental Anxiety
The aim of this study is to investigate whether the use of virtual reality (VR) headsets can have a positive effect on dental fear during dental procedures and stress induced by the dental environment.
- Trial name
- NCT07667023
- Testing
- Virtual reality headset, standard dental care
- Where
- Hungary
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Stress, Mental Health and General Well-being
Biomarkers of Environment Sensitivity
Most of the common mental disorders are heritable to a certain extent but environmental factors have an important role influencing whether the disorder will develop or not. These factors can be negative (e.g.
- Trial name
- NCT07594080
- Testing
- Williams Life Skills Stress Management Training
- Where
- Hungary
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Bone Loss, Tooth Movement
The Introduction of a Novel PAOO Technique
The aim of this study is to evaluate in a prospective, randomized, controlled clinical trail the effectiveness of preorthodontic piezotomy combined with a buccal bone augmentation (in other name periodontlly accelerated…
- Trial name
- NCT05264480
- Testing
- Bone augmentation with minimally invasive corticotomy (piezotomy), Bone augmentation without corticotomy
- Where
- Hungary
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Intrabony Periodontal Defect
Comparison of MIST With PRF and GBT With PRF in the Treatment of Intrabony Periodontal Defect. A Prospective RCT
The aim is to evaluate in a prospective, randomized, controlled clinical study the healing of a MIST procedure combined with PRF, or GBT combined with PRF.
- Trial name
- NCT06768424
- Testing
- Guided biofilm therapy, Platelet Rich Fibrin, Minimally Invasive Surgical Technique
- Where
- Hungary
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Hearing Loss, Screening
Adaptation of Pediatric Speech Audiometry Tests Into Other Languages
The objective of this study was to offer a comprehensive framework for the adaptation of speech audiometric tests into other languages.
- Trial name
- NCT07156825
- Where
- Hungary
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Injury Prevention, Shoulder Injuries
Shoulder Injury Prevention in Adolescent Handball Players Based on Scandinavian Protocols
This cluster-randomised controlled trial will evaluate the effects of two internationally recognised shoulder injury prevention programmes - the Swedish Shoulder Control programme and the Norwegian Oslo Sports Trauma Research…
- Trial name
- HBSP-HU-25 (NCT07146243)
- Testing
- Swedish Shoulder Control Programme, Norwegian OSTRC Shoulder Injury Prevention Programme
- Where
- Hungary
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Mobility Difficulty, Exercise
Teaching the Getting Up From the Floor Among Long-Term Care Facility Residents
The aim of this study is to determine the effect of teaching the getting up from the floor using the Backward Chaining Method on functional mobility, muscle strength, fear of falling, and life-space mobility among among long-term…
- Conditions
- Mobility Difficulty, Exercise, ELDERLY PEOPLE
- Trial name
- NCT06908317
- Testing
- floor rise training using backward chaining method
- Where
- Hungary
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Autism Spectrum Disorder (ASD)
Associations of Autistic Traits and Feeding Difficulties
The objective is to assess the prevalence of autistic traits and feeding disorders in the general population.
- Trial name
- BAMBI2025 (NCT07188870)
- Where
- Hungary
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Pectus Excavatum, Pectus Deformity
Assessing Virtual Reality for Perioperative Anxiolysis in Adolescents Undergoing MIRPE Surgery
In this randomized control trial, investigators would like to assess as primary objective the effectiveness of VR in anxiolysis via using State Trait Anxiety- Inventory test various time during the perioperative period with…
- Trial name
- NCT06446518
- Testing
- Virtual reality exposure
- Where
- Hungary
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Localized Gingival Enlargement, Epulides
Periodontal Plastic Reconstruction of Soft Tissue Dehiscences After the Removal of Localized Gingival Enlargements
Non-inflammatory recessions and Miller class I-II-III. mucogingival defects after elimination of localized gingival enlargements are frequently encountered challenges in the daily practice. In Miller class II-III.
- Conditions
- Localized Gingival Enlargement, Epulides, Recurrence, Periodontal; Lesion
- Trial name
- NCT06210789
- Testing
- Surgical excision
- Where
- Hungary
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Gingival Recession, Generalized
NovoMatrix in Gingival Recession Coverage: Case Series
Twenty patients seeking treatment for gingival recession coverage, ranging from 20-70 years of age with multiple Miller Class I or II buccal gingival recessions (depth≥3 mm, at least 3 adjacent teeth) will be recruited for this…
- Trial name
- NCT06409468
- Testing
- Subperiostal tunnel in conjunction with Novomatrix
- Where
- Hungary
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Breastfeeding Education, Lactating Mother
Breastfeeding Advices on OTC Medicines With the Internet: What is the Best Medium
Pharmacotherapy for lactating women in Hungary presents a unique challenge. While certain medications may pose risks to the infant or reduce breast milk production, the unnecessary avoidance of treatment can also be harmful.
- Conditions
- Breastfeeding Education, Lactating Mother, Breastfeeding Mothers, Lactation
- Trial name
- LACT-ED (NCT06863597)
- Testing
- Video content, Written content, Podcast content
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Gingivitis and Periodontal Diseases
Investigating the Periodontal Status of Traditional and Heated Tobacco Product Users
This cross-sectional observational study aims to compare the clinical and radiographic periodontal status, as well as gingival crevicular fluid volume, among cigarette smokers, heated-tobacco product users, and non-smokers.
- Trial name
- INPER-THT (NCT06784817)
- Where
- Hungary
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Periapical Diseases, Radicular Cyst
PRF Membrane and Recovery After Periapical Surgery: A 3D Imaging Study
The goal of this clinical trial is to determine whether a PRF (platelet-rich fibrin) membrane helps improve recovery after periapical surgery in adults.
- Conditions
- Periapical Diseases, Radicular Cyst, Granuloma, Postoperative Complications
- Trial name
- NCT06739200
- Testing
- Platelet-Rich Fibrin (PRF) Membrane
- Where
- Hungary
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Vitamin D Deficiency
Controlled, Randomized, Four-arm Comparative, Open Label, Multi-centric Clinical Trial to Compare the Efficacy and Safety Parameters of the Once-a-week or Once-a-month Administered 7000 IU, or 30000 IU Vitamin D (Cholecalciferol) to a 1000 IU Dosage Applied Daily in Vitamin D Deficient Patients
Circa-annual variations in 25-hydroxyvitamin D [25(OH)D] levels have been well established, and there also seems to be an effect of season on bone turnover and bone mass.
- Trial name
- NCT02069990
- Testing
- Cholecalciferol
- Where
- 2 sites in Hungary
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Vasodilation, Oral Soft Tissue Conditions
Investigation of Endothelium-dependent Vasodilation in Human Gingiva
The first aim of this study is to create a cumulative dose-response curve for acetylcholine in men (low serum estrogen levels) to determine the lowest concentration with which we can induce a maximal vasodilation effect on the…
- Trial name
- NCT06454084
- Testing
- Acetylcholine Chloride
- Where
- Hungary
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Dental Implants, Single-Tooth, Dental Impression Technique
Digital vs Conventional Impression in Capturing the Emergence Profile Around Maxillary Anterior Implant-supported Crowns
This study compares conventional impression and cast fabrication to direct/indirect digital scannig and 3D printed casts regarding their accuracy in replicating the peri-implant emergence profile of single implants in the…
- Trial name
- NCT06425770
- Testing
- indirect digital impression and 3D printed cast, direct digital impression, conventional impresion and cast
- Where
- Hungary
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Dental Implants, Single-Tooth, Dental Implant-Abutment Design
Effect of Abutment Configuration on Peri-implant Soft and Hard Tissue in the Esthetic Zone - Randomized Clinical Trial
The aims of our study are to investigate in patients with immediate implantation replacing a single tooth in the maxillary anterior (#FDI 15-25) region the effect of (a) custom vs cylindrical stock healing abutments, then (b)…
- Trial name
- NCT06407271
- Testing
- CAD/CAM custom ZrO2 healing abutment, Cylindrical ZrO2 healing abutment
- Where
- Hungary
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Periodontal Diseases
Treatment of Periodontal Intrabony Defects With A-PRF or OFD
The aim of this randomized clinical trial was to clinically evaluate and compare the healing of intrabony defects after treatment with advanced platelet-rich fibrin (A-PRF+) toped flap debridement (OFD) in periodontitis patients.
- Trial name
- NCT04823572
- Testing
- A-PRF/OFD
- Where
- Hungary
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Semmelweis University