Clinical trials: sponsored by Shanghai Mental Health Center
Alcohol Use Disorder (AUD)
High Intensity Alternating Current Stimulation as a Neuromodulation Therapy for Alcohol Use Disorder: A Pilot Study
This one-arm pilot study aims to evaluate the preliminary clinical, behavioral, and neurophysiological effects of high-intensity transcranial alternating current stimulation (HI-tACS) in individuals with alcohol use disorder…
- Trial name
- HITACS-AUD (NCT07227545)
- Testing
- HI-tACS
- Where
- China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Gaming Disorder, Hazardous Gaming
Effectiveness of a Mobile Cognitive-Behavioral Therapy-Based Early Intervention on Adolescent Hazardous Gaming
The investigators established a mobile-based early intervention on adolescent hazardous gaming and verified its effectiveness.
- Conditions
- Gaming Disorder, Hazardous Gaming, Cognitive Behavioral Therapy
- Trial name
- NCT06811571
- Testing
- mobile CBT-based early Intervention on Adolescent Hazardous Gaming
- Where
- China
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Schizophrenia With Auditory Hallucinations
Frequency- and Intensity-Dependent After-Effects of High-Definition Transcranial Alternating Current Stimulation on Resting-State Electroencephalography
This study aims to investigate the after-effects of high-definition transcranial alternating current stimulation (HD-tACS) with varying parameters on resting-state brain activity in patients with schizophrenia experiencing…
- Trial name
- NCT07798804
- Testing
- high-definition transcranial alternating current stimulation(HD-tACS)
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Anorexia Nervosa, Caregiver Burden
Online FBT-DBT Caregiver Intervention for Caregivers of Individuals With Anorexia Nervosa
Anorexia nervosa (AN) is a severe psychiatric disorder characterized by a chronic and relapsing course. Caregivers of individuals with AN often experience substantial caregiving burden, emotional distress, and impairment in…
- Trial name
- NCT07734779
- Testing
- Online FBT-DBT Intervention, Online Supportive Psychological Intervention
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Mental Health Literacy
Non-inferiority of Virtual vs. Traditional Methods in Adolescent Mental Health Literacy
The goal of this clinical trial is to determine whether a digital psychological literacy program delivered by an AI-powered virtual agent is non-inferior to traditional teacher-led instruction in improving mental health literacy…
- Trial name
- NCT07238842
- Testing
- Teacher-Led Psychological Literacy Instruction, Virtual Agent-Delivered Psychological Literacy Training
- Where
- China
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Obsessive-Compulsive Disorder, Tic Disorder
Pathogenesis of Pediatric Obsessive-compulsive Disorder: Based on the Microbiota-gut-brain Axis
This study aims to investigate the characteristics of the microbiota-gut-brain axis in pediatric patients with obsessive-compulsive disorder (OCD) through performing an integrated analysis of gut microbiota, serum metabolomics…
- Trial name
- NCT06754319
- Where
- China
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Major Depressive Disorder (MDD)
iMORE+ Study: A Multi-Omics Cohort Study of Major Depressive Disorder
Major depressive disorder (MDD) is a common mental health condition characterized by substantial clinical heterogeneity and variability in treatment response.
- Trial name
- iMORE+ (NCT07735143)
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Stress, Anxiety
An ISO Principle-Based Music Intervention for Reducing Stress, Anxiety, and Depression
This study aims to evaluate the effectiveness of a music-based intervention, guided by the ISO principle, in reducing stress, anxiety and depression induced by work, family or others among adults.
- Conditions
- Stress, Anxiety, Depression in Adults
- Trial name
- ISO4SAD (NCT07055061)
- Testing
- ISO Principle Music Intervention, DUL Principle Music Intervention, ISO Principle Music Intervention with Waiting-list
- Where
- 2 sites in China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Meditation, Mindfulness
Investigation of Functional Brain Network in Altered Meditation State With Multimodal Neuroimaging
The purpose of this study is to investigate functional brain network in altered meditation state with multimodal neuroimaging.
- Trial name
- NCT05020301
- Testing
- external meditation guided audio, internal meditation guided audio
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Extrapyramidal Symptoms, Drug-induced Parkinsonism
A Computer-Assisted Tool for Objective Assessment of Extrapyramidal Symptoms
This prospective, single-center observational study aims to develop and validate a computer-assisted tool for the objective quantitative assessment of extrapyramidal symptoms (EPS).
- Conditions
- Extrapyramidal Symptoms, Drug-induced Parkinsonism, Akathisia, Drug-Induced, Tardive Dyskinesia (TD)
- Trial name
- NCT07715994
- Testing
- Computer-Assisted Objective Assessment of Extrapyramidal Symptoms
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Schizophrenia, Cognitive Impairment
Eye-Movement Intervention for Cognitive Impairment Across Schizophrenia Spectrum
The goal of this clinical trial is to determine whether a gamified eye-movement intervention can improve cognitive function in individuals across the schizophrenia spectrum, including clinical high-risk individuals, first-episode…
- Conditions
- Schizophrenia, Cognitive Impairment, Clinical High Risk for Psychosis
- Trial name
- NCT07702526
- Testing
- Eye-Movement Training, Finger-Controlled Game Training
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Methamphetamine Use Disorder
Cerebellum-Prefrontal Paired-Pulse Stimulation for Methamphetamine Use Disorder
To investigate the mechanism and efficacy of a novel repetitive transcranial magnetic stimulation (rTMS) intervention model with paired cerebellar-medial prefrontal cortex (mPFC) pulses on methamphetamine use disorder patients…
- Trial name
- NCT06457230
- Testing
- Paired Associative Stimulation Targeting the Cerebellar-mPFC
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Gambling Disorder
Effect of High-Intensity Transcranial Alternating Current Stimulation on Gambling Disorder: A Randomized Controlled Trial
The investigators assume that High-intensity transcranial Alternating Current Stimulation (HI-tACS) could improve gambling disorder patients' executive-control function by modulating abnormal neural activity, particularly…
- Trial name
- HITACSRCT-GD (NCT07228182)
- Testing
- HI-tACS
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Bipolar Disorder (BD), Healthy Control
An Exploratory Study on the Prediction of Recurrence Risk of Bipolar Disorder Using Sentiment Analysis Technology Based on Multi-modal Feature Fusion
Bipolar disorder (BD) has become a significant public health problem with complex clinical manifestations, difficult treatment, and poor prognosis.
- Trial name
- NCT07573839
- Testing
- This is an observational study with no intervention.
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Obsessive - Compulsive Disorder
Neural Mechanisms of the Sensorymotor Circuit in Sensory Phenomena in OCD
The goal of this clinical study is to investigate the neural mechanisms of abnormal sensory phenomena in patients with Obsessive-Compulsive Disorder and to evaluate whether modulation of the insula-supplementary motor area…
- Trial name
- NCT07480408
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Gaming Disorder
A Study to Evaluate the Effectiveness of Group Gaming Interventions for Individuals With Problematic Gaming Behavior and Gaming Disorder.
This is a randomized, parallel-group, two-arm study design registered with the Chinese Clinical Trial Registry. The study divides participants into an intervention group and a control group in the same ratio.
- Trial name
- NCT07363850
- Testing
- group gaming interventions
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Anxiety Disorders
Validation of the Accuracy of an AI-Based System for Diagnosing Anxiety Disorders
The trial aimed to evaluate the efficacy of an artificial intelligence-based system for diagnosing anxiety disorders. Specifically, it sought to determine whether the system's assessment validity is non-inferior to that of…
- Trial name
- NCT07311655
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Depressive Disorder
Validation of the Accuracy of an AI-Based System for Diagnosing Depressive Disorders
The trial aimed to evaluate the accuracy of an artificial intelligence-based system for diagnosing depressive disorders. Specifically, it sought to determine whether the system's assessment validity is non-inferior to that of…
- Trial name
- NCT07311668
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Depression
Neural Mechanisms of Temporal Interference Stimulation on Improving Social Reward Function in Depression
Major depressive disorder (MDD) is a mood disorder characterized primarily by low mood, diminished interest, and reduced energy.
- Trial name
- NCT07287878
- Testing
- Temporal Interference Simulation(TIS), Temporal Interference Stimulation(TIS)
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Bulimia Nervosa, Binge Eating Behaviour
Wise Eating: A Guided Digital DBT-Based Intervention for Binge Eating
Bulimia Nervosa (BN), characterized by binge eating and purging behaviors, constitutes a chronic psychiatric disorder predominantly affecting young females, characterized by high prevalence and relapse rates.
- Conditions
- Bulimia Nervosa, Binge Eating Behaviour, Anorexia Nervosa, Eating Disorders
- Trial name
- NCT07143214
- Testing
- online dialectical behavior therapy, Waitlist and psychoeducation
- Where
- China
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center