Clinical trials: sponsored by Technical University of Munich
Cancer, Shared Decision Making
Use of and Attitudes Towards Large Language Models for Health Information Among People With Cancer, the Public, and Health-care Professionals
This cross-sectional survey examined how people with cancer, the general public and health-care professionals use large language models (LLMs) such as ChatGPT for health information, what they expect from them, how comfortable…
- Conditions
- Cancer, Shared Decision Making, Artificial Intelligence
- Trial name
- NCT07526441
- Where
- Germany
- Volunteers
- 6,632 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Mental Health, Empathy
Strengthening Relationships and Mental Health Through a Couples-Based Economic Empowerment Intervention
This psychosocial sub-study is embedded within a larger cluster-randomised controlled trial titled Disentangling and Preventing Economic Violence against Women (ECOVI), conducted in rural and urban communities across Maharashtra…
- Conditions
- Mental Health, Empathy, Relation, Interpersonal
- Trial name
- NCT07108049
- Testing
- Let us Grow Together: Economic Wellbeing for Families
- Where
- 2 sites in India
- Volunteers
- 4,552 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Cardiovascular Diseases, Pediatric Cancer
Cardiac Impairments Following Pediatric Cardiotoxic Anti-cancer Treatment
This study aims at investigating the feasibility of recruitment and application of a method regarding early detection of subclinical changes in cardiac health after completion of acute cancer treatment during childhood and…
- Trial name
- NCT05261256
- Testing
- Exercise stress echocardiography
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Norm, Social, Autonomy
Gender-Transformative Interventions and Normative Beliefs About Reproductive Decision-Making
The ECOVI trial is a two-arm cluster randomized controlled trial (cRCT) conducted in rural and urban communities across Maharashtra, Andhra Pradesh, and Rajasthan, India, and funded by the European Research Council (ERC).
- Conditions
- Norm, Social, Autonomy, Relation, Family
- Trial name
- Beyond (NCT07734961)
- Testing
- Let Us Grow Together: Economic Wellbeing for Families
- Where
- India
- Volunteers
- 2,276 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Diagnoses Disease
HEARTBEAT-TROP. Polyethylene Glycol Precipitation to Unmask Macrotroponin
Troponin elevation can, among others, be due to myocardial infarction, acute inflammation or structural heart disease. Formation of macrocomplexes against troponin is an underestimated cause for persistent troponin elevation.
- Trial name
- MACRO-TROP (NCT07726420)
- Testing
- Polyethylene glycol precipitation, Transthoracic echocardiography
- Where
- Germany
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Healthy Volunteers, Muscle Hypertrophy
Glycolytic Phenotype (vLapeak) and Magnitude of Skeletal Muscle Hypertrophy After Resistance Training
The HyperLa study investigates whether a person's "glycolyticness"-the efficiency with which their body uses glycolysis for energy-can predict how much their muscles will grow (hypertrophy) in response to resistance training.
- Conditions
- Healthy Volunteers, Muscle Hypertrophy, Glycolysis, Moderately Trainend
- Trial name
- HyperLa (NCT07721766)
- Testing
- Hypertrophy-focused Resistance Training
- Where
- 8 sites in Finland, Germany and 2 more
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Gait Analysis on Healthy Adults
Comparison of AI-based Smartphone-derived Gait Parameters With the Gold Standard
This monocentric prospective cohort study evaluates the technical agreement between artificial intelligence (AI)-based smartphone-derived gait parameters and an optical motion-capture system as the current technical gold standard…
- Trial name
- NCT07613957
- Testing
- Gait analysis via vicon- and app-system
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Exercise Timing, Postprandial Glucose
Exercise Timing and Postprandial Glucose Responses
This interventional crossover study examines the effect of exercise timing relative to meal intake on postprandial glucose responses in healthy, physically active young adults.
- Trial name
- ExTime-Glu (NCT07434349)
- Testing
- Timed Endurance Exercise, No Exercise Control
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Knee Osteoarthritis, Knee Arthroplasty
Development of an Outcome Score for Patients With Knee Osteoarthritis and Knee Joint Endoprosthesis Using an App
Total knee arthroplasty (TKA) and total hip arthroplasty (THA) is one of the most frequent orthopedic procedures. Over 50% of patients report higher expectations than their surgeons, and 10-50% remain dissatisfied…
- Conditions
- Knee Osteoarthritis, Knee Arthroplasty, Hip Osteoarthritis, Hip Arthroplasty
- Trial name
- KneeApp (NCT07212699)
- Testing
- KneeApp
- Where
- Germany
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Dietary Carbohydrate Restriction, Energy Deficit
Metabolic Flexibility and Ketone Production During Energy Deficit
This randomized, interventional study examines the effects of short-term carbohydrate restriction, with and without caloric restriction, on indices of metabolic flexibility in healthy adults.
- Trial name
- MetaFlex (NCT07429058)
- Testing
- Low-Carbohydrate Diet, Standard Diet With Caloric Restriction
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Depressive Syndrom
Real-World NeuroModulate: Investigating Non-Invasive Brain Stimulation for Neuropsychiatric Disorders at TUM
In this study, patients diagnosed with a depressive syndrome and with a clinical indication for treatment will receive an acute course of transcranial magnetic stimulation (TMS).
- Trial name
- NCT07420322
- Testing
- iTBS Treatment
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Health, Energy Intake
Time-of-Day Effects of Fasted Exercise on Energy Intake
This trial's aim is to investigate the time-of-day effects (morning vs. evening) of fasted exercise on acute and 24h post-exercise energy intake.
- Conditions
- Health, Energy Intake, Eating Behaviors, Appetite
- Trial name
- NCT06947824
- Testing
- Fasted Morning Exercise (12h), Fasted Evening Exercise (6h), Fasted Evening Exercise (12h)
- Where
- Germany
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Endurance Training, No Training
Effect of Chronic Exercise on Human Thermogenic Adipose Tissue & Elucidation of Mechanisms
Physical exercise can stimulate heat production in our bodies. This is healthy because it burns sugar and fat. Heat production is influenced, among other things, by what is known as 'brown or beige adipose tissue', which is…
- Trial name
- ExBat (NCT07299604)
- Testing
- Endurance Training
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Lower Extremity Injuries
Prediction of Lower Extremity Injuries Using Lower Limb-worn Inertial Measurement Units
This study analyses questionnaires and inertial sensor data from 108 sports science students regarding previous lower extremity injuries, sports activity, and preventive measures, combined with the prospective development of an…
- Trial name
- PredKnee (NCT07289828)
- Testing
- IMU Data collection, Questionnaire
- Where
- Germany
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Mobility
Best Function of Range of Motion (cRCT)
Mobility is a crucial factor for independence and quality of life in older people. However, the majority of those in retirement homes are not physically active to maintain mobility and independence.
- Trial name
- bestform (NCT04207307)
- Testing
- Multimodal exercise program, Usual Care
- Where
- Germany
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Taurine, Aging, Biological
Effects Of Daily Taurine Intake For 6 Months On Biological Age and Body Metabolism Indicators As Well As Physical Fitness In 55-75-year-old Women And Men
The goal of this clinical trial is to investigate the effect of taking 4 grams of taurine by older adults on aging processes over a period of 6 months.
- Conditions
- Taurine, Aging, Biological, Physical Activity, Metabolic Health
- Trial name
- TauAge (NCT06613542)
- Testing
- 4g of taurine daily
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Diabetes Mellitus, Type 1
Anti-viral Action Against Type 1 Diabetes Autoimmunity
The study GPPAD-05 AVAnT1A is a phase 4 clinical trial intending to enroll 2252 children, who will be randomly assigned to receive COVID-19 vaccination (Comirnaty® 3 μg Omicron XBB.1.5 or new variant Comirnaty vaccines ) or…
- Trial name
- NCT06452654
- Testing
- Comirnaty Injectable Product, Sodium Chloride 0.9% Inj
- Where
- 9 sites in Austria, Belgium and 3 more
- Volunteers
- 2,252 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Participants of the Be-MaGIC-Study 2009
Prospective Follow-up, Marathon, Long Term, Inflammation and Cardiovascular System
Pro-MagIC is a prospective observational study and includes participants of the Be-MaGIC-Study 2009 (n=277/NCT00933218). We aim to detect exercise-induced physiological changes (inter alia of the cardiovascular system) induced by…
- Trial name
- Pro-MagIC (NCT04166903)
- Where
- Germany
- Volunteers
- 277 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Breathing Exercises
Relaxation Effects of Personalized Breathing Exercises for Healthy College Students
Stress plays a major role in the etiology and pathogenesis of anxiety and depression. Relaxation therapies, such as breathing exercises, can reduce stress and increase relaxation. This study has two aims.
- Trial name
- NCT06121596
- Testing
- Breathing Exercise
- Where
- Germany
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Cardiovascular Prevention, Healthy
Connect2Move: Valorization of Natural Cardio Trekking Hiking Trails
Regular exercise improves performance and reduces the risk of cardiovascular disease. Endurance and strength training are therefore forms of therapy with a high level of evidence in the prevention and rehabilitation of…
- Conditions
- Cardiovascular Prevention, Healthy, Healthy Lifestyle
- Trial name
- Connect2Move (NCT05226806)
- Testing
- Measurement of cardiorespiratory performance in 3 different settings, GENERAL CARDIO HIKES AS PART OF GENERAL TOURIST OFFER OF MUNICIPALITIES
- Where
- Germany
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich