Clinical trials: sponsored by UNC Lineberger Comprehensive Cancer Center
Cervical Cancer
Finding Barriers and Designing Solutions to Promote Women s Cancer Screening in South Africa
The primary aim of the study explore drivers of cervical cancer screening and barriers contributing to low screening coverage among women in South Africa.
- Trial name
- FIND (NCT05414097)
- Testing
- Semi-structured focus group discussions - Women, semi-structured focus groups discussions - Men, In-depth key stakeholders interviews
- Where
- South Africa
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Hematological Disorder
Intervention to Address Psychosocial Needs Among Socially Disadvantaged Older Adults With Cancer
The purpose of this study is to convene a group of diverse North Carolina-based community representatives (patients, caregivers, leaders of faith-based organizations, social workers, and patient navigators) to inform the…
- Trial name
- NCT05828654
- Testing
- Focus Group Discussions and Semi-structured Interviews, Training community lay navigators
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Breast Screening
Novel MRI Sequence MR Fingerprinting in Breast MRI Feasibility Study
The purpose of this study is to evaluate potential clinical efficacy of a novel magnetic resonance imaging (MRI) approach, MR fingerprinting, capable of providing quantitative measures of important tissue properties, which could…
- Trial name
- NCT03846947
- Testing
- MR Fingerprinting
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Cervical Cancer, Uterine Cervical Neoplasms
Effect of Human Papillomavirus Self-Collection on Cervical Cancer Screening in High Risk Women: My Body, My Test 3
This study will investigate whether cervical cancer screening completion among under-screened women could be improved by offering HPV (human papillomavirus) testing by at-home self-collection followed by screening invitation…
- Conditions
- Cervical Cancer, Uterine Cervical Neoplasms, Human Papillomavirus
- Trial name
- MBMT-3 (NCT02651883)
- Testing
- Screening invitation (with education), Self-collection for HPV testing
- Where
- United States
- Volunteers
- 665 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Colorectal Cancer
A Patient Portal Tool, E-assist, for Supporting CRC Screening
To compare patient perceptions, intent to screen, and screening use among those using a patient portal with and without a colorectal cancer (CRC) screening decision support tool, e-assist.
- Trial name
- NCT02798224
- Testing
- e-assist: Colon Health, Healthwise Educational Program
- Where
- United States
- Volunteers
- 1,826 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
HPV Vaccine, Provider Communication Practices
Mobile Coaching to Improve HPV Vaccine Delivery
The purpose of this study is to examine the feasibility of using Checkup Coach, a mobile coaching intervention, to improve the way that primary care providers recommend HPV vaccination to adolescent patients and their parents.
- Conditions
- HPV Vaccine, Provider Communication Practices, Vaccine Recommendation Practices
- Trial name
- NCT05105711
- Testing
- QI coaching intervention
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Colorectal Cancer
A Culturally-adapted Colorectal Cancer Screening Decision Aid Designed for American Indians
Experts note that in order to continue reducing the US cancer burden, it is critical that investigators "more completely apply discoveries in cancer prevention we have already made." Thus, it is important to research strategies…
- Trial name
- NCT03569761
- Testing
- Colorectal Cancer Screening Decision Aid, Control Group
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Neoplasm of Lung, Decision Support Techniques
Effect of Incidental Findings Information on Lung Cancer Screening Intent
This online randomized controlled trial seeks to determine if inclusion of incidental findings information in a lung cancer screening decision aid affects screening intent among screening-eligible individuals.
- Conditions
- Neoplasm of Lung, Decision Support Techniques, Mass Screening
- Trial name
- NCT04432753
- Testing
- Lung Cancer Screening Decision Aid with Incidental Findings Information, Lung Cancer Screening Decision Aid without Incidental Findings Information
- Where
- United States
- Volunteers
- 419 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Cigarette Smoking Behavior
Enhancing Source Credibility in Tobacco Regulatory Communications
This study will assess the impact of cigarette constituent messages with and without FDA source and quit information in a randomized controlled trial.
- Trial name
- NCT03339206
- Testing
- Constituent message with FDA and quitline, Constituent message without FDA and quitline, Littering message (Control)
- Where
- United States
- Volunteers
- 845 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Endometrium Cancer, Sentinel Lymph Node
Multimedia Aid Gynecologic Counseling and Consent
This is an interventional trial to introduce two short animated videos into preoperative counseling/consent and to compare patient comprehension and satisfaction with a multimedia approach compared to standard of care currently.
- Conditions
- Endometrium Cancer, Sentinel Lymph Node, Perioperative/Postoperative Complications
- Trial name
- NCT03899441
- Testing
- Video
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Cancer, Breast, Cognitive Impairment
Feasibility of an 8-week Tai Chi Chuan Intervention for Breast Cancer Survivors
Purpose:To gather preliminary data and to determine the feasibility and acceptability of an 8-week Tai Chi intervention for adults cancer survivors (survivors) who report experiencing cognitive impairment, and to perform…
- Trial name
- NCT03196037
- Testing
- Tai Chi
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Breast Cancer
Mammography Reminders for Encouraging Women to Undergo Regular Mammography Screenings for Breast Cancer
RATIONALE: Mammography reminders may encourage women to undergo regular mammography screenings for breast cancer. PURPOSE: This randomized clinical trial is studying three different mammography reminder interventions to compare…
- Trial name
- NCT01148875
- Testing
- Mammography appointment reminders; telephone counseling
- Volunteers
- 3,547 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Breast Cancer, Endometrial Cancer
Genistein in Preventing Breast or Endometrial Cancer in Healthy Postmenopausal Women
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of genistein may be effective in preventing breast or endometrial cancer.
- Trial name
- NCT00099008
- Testing
- Genistein
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center