Clinical trials: sponsored by University College, London
Anxiety Acute, Anxiety Fear
Paediatric Peri-operative Anxiety: Does the Little Journey App Help?
To evaluate the clinical effectiveness of a virtual reality psychological preparation app at reducing peri-operative anxiety and its associated sequelae in children aged 3-12 years old undergoing ambulatory surgery compared to…
- Conditions
- Anxiety Acute, Anxiety Fear, Peri-operative, Psychological Distress
- Trial name
- NCT03797716
- Testing
- Little Journey app
- Where
- 17 sites in United Kingdom
- Volunteers
- 596 people, healthy volunteers welcome
- Sponsor
- University College, London
Healthy
Development of Novel MR Techniques Using Volunteer Participants
Using magnetic resonance (MR) imaging or spectroscopy as part of clinical research typically involves developing new MR protocols.
- Trial name
- NCT05943249
- Testing
- magnetic resonance
- Where
- United Kingdom
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University College, London
Pregnancy Related
Legacies and Futures: Measuring Roles of Resilience and Vulnerability in Pregnancy and Birth Outcomes
Pregnancy care typically assumes patients are heterosexual married women whose gender matches their assigned sex (i.e., cisgender), stigmatizing patients and creating limitations, blocking affirming care.
- Trial name
- NCT05365828
- Where
- 14 sites in United Kingdom
- Volunteers
- 945 people, healthy volunteers welcome
- Sponsor
- University College, London
Cancer, Lung Cancer
The SUMMIT Study: A Cancer Screening Study
The SUMMIT Study will enrol 13,000 participants in order to investigate how cancer screening can be improved and delivered. The SUMMIT Study has two main aims: the first is to clinically validate a blood test for detecting…
- Trial name
- SUMMIT (NCT03934866)
- Testing
- Low Dose CT scan
- Where
- United Kingdom
- Volunteers
- 13,035 people, healthy volunteers welcome
- Sponsor
- University College, London
Sleep Disordered Breathing
3D Printing of Positive Airway Pressure (PAP) Therapy Masks: a Single Site Pilot and Feasibility Study
This study is a single site pilot and feasibility study. We propose that 3D printing could be used to create customised masks for patients requiring Positive Airway Pressure (PAP) therapy.
- Trial name
- 3DPiPPIn (NCT04179123)
- Testing
- Customised PAP interfaces
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University College, London
DMD, BMD
Defining Outcome Measures for Behavioural and Emotional Problems in Dystrophinopathies
Study aims to develop and to evaluate the neurophysiological and physiological response to a classical conditioning task.To better understand how Duchenne Muscular Dystrophy (DMD) and Becker Muscular Dystrophy (BMD) impacts…
- Trial name
- D-BRAIN (NCT06581887)
- Testing
- Classical conditioning task
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University College, London
Athletes, Healthy
The Influence of Chlorella Supplementation on Running Performance
Algae, such as chlorella, are gaining popularity as a nutritious additive to whole food or as a supplement. They contain a variety of beneficial nutrients like vitamins, minerals, healthy fats, and amino acids, which can have…
- Trial name
- NCT06479993
- Testing
- Chlorella supplementation
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University College, London
Dentatorubral-Pallidoluysian Atrophy
Dentatorubral-pallidoluysian Atrophy Natural History and Biomarkers Study
DRPLA Natural History and Biomarkers Study (DRPLA NHBS) is a prospective observational study that will lay the foundation for clinical trials in DRPLA.
- Trial name
- DRPLA NHBS (NCT06273150)
- Testing
- Positive genetic test for pathological expansion in ATN1
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University College, London
Health Behaviour, Tobacco Prevention
Intervention for Adolescent Tobacco Initiation Prevention
This school-based cluster randomized controlled trial aims to assess the feasibility of implementing the Adolescent Tobacco Initiation Prevention (IATIP) and evaluate the potential efficacy of IATIP in preventing tobacco…
- Conditions
- Health Behaviour, Tobacco Prevention, Well-being
- Trial name
- IATIP (NCT06399588)
- Testing
- Intervention for Adolescent Tobacco Initiation Prevention (IATIP)
- Where
- Bangladesh
- Volunteers
- 1,280 people, healthy volunteers welcome
- Sponsor
- University College, London
Physical Inactivity
A Test of Different Incentives and How Effectively They Motivate Walking Behaviour
This study aims to test the effectiveness of different types of incentives to motivate walking among people who use a tracker app.
- Trial name
- NCT06395233
- Testing
- BetterPoints App
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University College, London
Vascular Diseases
Quantitative Perfusion Imaging Using Contrast Enhanced Perfusion Ultrasound, MRI and Perfusion Angiography
Peripheral Arterial Disease is the narrowing and blocking of the blood vessels that supply the legs and feet. It is a common and progressive condition that affects patients of all backgrounds and genders and is more common in…
- Trial name
- QPiPAD (NCT06103708)
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University College, London
Sarcopenia, Chronic Lung Disease
Feasibility of Proteomics in Chronic Lung Disease With Sarcopenia
Sarcopenia, the loss of muscle mass and strength with ageing, is a prevalent condition in older adults, particularly those with chronic lung diseases like COPD and interstitial lung disease.
- Trial name
- NCT06312774
- Testing
- This is observational study
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University College, London
Sedentary, Overweight
The Efficacy of Chlorella Supplementation on Health and Performance Following a 12-week Training Programme
Algae are an emerging functional food source that are gaining traction and popularity in biopharmaceutical, nutraceutical, and biotechnology industries.
- Trial name
- NCT05639634
- Testing
- Chlorella supplementation, 12 week cardiovascular training programme
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University College, London
Duchenne Muscular Dystrophy
Outcome Measures in Duchenne Muscular Dystrophy: A Natural History Study
Novel emerging therapies for Duchenne Muscular Dystrophy (DMD) require a deeper understanding of DMD natural history. This study aim to assess the natural history of DMD through a composite assessment tool capable of capturing…
- Trial name
- NCT02780492
- Testing
- Set of assessment tools
- Where
- 5 sites in France, Netherlands and 1 more
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University College, London
Dementia
SOcial coNNEction in Long-Term Care Home Residents
This study aims to develop a new measure which can accurately assess social connection for people with dementia living in long-term care homes.
- Trial name
- SONNET (NCT05315960)
- Where
- 2 sites in Canada, United Kingdom
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University College, London
Inflammation, Periodontal Diseases
Mechanisms of Acute Inflammation Following Periodontal Treatment
Periodontitis (gum disease) is a chronic inflammatory disease linked to a imbalance of oral microbiome. The most usual treatment involves removal of sub and supra-gingival plaque and calculus otherwise known as Non-surgical…
- Trial name
- MANTRA (NCT05178563)
- Testing
- IPT+PDT
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University College, London
Obesity
Magnetic Resonance Imaging in Obesity
Obesity and its related conditions account for up to 5%of all health care spending in the UK and this is expected to double by 2030.
- Trial name
- NCT03528187
- Testing
- MRI, Written Consent
- Where
- United Kingdom
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University College, London
Exercise, Metabolism
Metabolic Responses to Exercise and Recovery
Exercise benefits health through diverse metabolic processes and is central to healthy ageing. However, intense exercise also challenges the body, causing cellular damage that must be repaired.
- Trial name
- NCT06088108
- Testing
- Cornell treadmill exercise protocol
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University College, London
Cardiovascular Diseases, Cardiotoxicity
Cancer Treatment Related Cardiovascular Toxicity: Comprehensive Myocardial and Vascular Phenotyping
Observational prospective cohort study designed to assess the mechanisms of fluoropyrimidine induced cardiovascular toxicity.
- Conditions
- Cardiovascular Diseases, Cardiotoxicity, Fluorouracil Adverse Reaction, Malignancy
- Trial name
- PC-TOX (NCT06048458)
- Testing
- Cardiovascular magnetic resonance with stress perfusion, CT coronary angiography, Retinal OCT angiography
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University College, London
Loneliness, Anxiety
Is Signposting to Online Peer Support Helpful in Decreasing Loneliness in Parents of Children With Long-term Conditions and Disabilities?
The present study aims to evaluate whether signposting to online peer support will be associated with a significant decrease in self-reported loneliness for parents of children with long-term conditions and disabilities.
- Conditions
- Loneliness, Anxiety, Anxiety Disorder, Depression
- Trial name
- NCT05373121
- Testing
- Online Peer Support
- Where
- United Kingdom
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University College, London