Clinical trials: sponsored by University Hospital, Angers
Medical Education, Clinical Competence
Emergency Structured Clinical Examination Training bOX
This study assessed whether a training toolbox called ECOX could help medical students prepare for their objective structured clinical examination (OSCE) during an emergency medicine clerkship.
- Conditions
- Medical Education, Clinical Competence, Examination-Related Anxiety
- Trial name
- ECOX (NCT06124430)
- Testing
- ECOX workplace-based training toolbox
- Where
- France
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Human Health in Extreme Conditions
CHOICE KERGUELEN 1: Consequences of Longterm Confinement on Immunity in the Sub-Antarctic Islands: Inclusion of Volunteers Before Departure to the Kerguelen Islands
Living for long periods in extreme environments-like Antarctic research stations or space missions-can have a significant impact on human health, especially on the immune system.
- Trial name
- NCT07065253
- Testing
- blood ponction, urines collection, hair collection
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Autosomal Dominant Spinocerebellar Ataxia (SCA1, 2,3,6,7,27B)
Autosomal Dominant Spinocerebellar Ataxias and Social Cognition
Spinocerebellar ataxias are a group of rare neurodegenerative diseases, clinically and genetically highly heterogeneous, with an estimated mean prevalence of 2.7 per 100,000 population.
- Trial name
- SoCoSca (NCT07099651)
- Testing
- tests
- Where
- France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Long COVID
Characterization of the Immunometabolic Signature in Long COVID-19.
The primary objective of this study is to identify immunometabolic signatures associated with Long COVID in plasma and peripheral blood mononuclear cells (PBMC).
- Trial name
- LoCo-ImMet (NCT05758480)
- Testing
- Blood sample (at inclusion and 6 months later), Patient questionnaires (at inclusion and 6 months later)
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Time Between Hysterectomy and Resumption of Sexual Relations, Sexual Function
Impact of Time on Sexual Function (FSFI® Score) After Hysterectomy
In France, more than 62 000 hysterectomies are performed each year. Female sexual function is the result of multiple psychological, social and physiological factors.
- Trial name
- ISHYS (NCT05728281)
- Testing
- Recommended time after hysterectomy
- Where
- France
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and Neck, Melanoma Neoplasms
Evaluation of Skin Tests in Biotherapy Allergies
Biotherapies are biological (extracted from an organism or living tissue) or biotechnological drugs used in the treatment of multiple conditions, such as autoimmune inflammatory diseases, cancers, and hematologic diseases.
- Conditions
- Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and Neck, Melanoma Neoplasms, Small Cell Bronchial Carcinomas, Bronchial Carcinoma
- Trial name
- ETCABIO (NCT06971848)
- Testing
- Drug skin tests (investigating hypersensitivity to a biotherapy)
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Human Health in Extreme Conditions
CHOICE KERGUELEN 2 : Consequences of Longterm Confinement on Immunity in the Sub-Antarctic Islands : Follow-up of Volunteers on the Kerguelen Islands
Living for long periods in extreme environments-like Antarctic research stations or space missions-can have a significant impact on human health, especially on the immune system.
- Trial name
- NCT07275489
- Testing
- blood ponction, urines collection, hair collection
- Where
- French Southern and Antarctic Lands
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Social Cognition
Social Cognition in Patients With Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis, also known as Charcot disease, is a neurodegenerative disease evidenced by gradual paralysis of the muscles involved in voluntary motor function.
- Trial name
- COSISLA (NCT04406675)
- Testing
- neuropsychological test
- Where
- France
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Chronic Insomnia
Facial Emotion Recognition in Insomnia and Emotional Regulation
Introduction Chronic insomnia is a prevalent disorder in the general population, affecting up to 20% according to French National Institute of Health and Medical Research, leading to a decline in quality of life and an increased…
- Trial name
- REFIRE (NCT06251258)
- Testing
- Facial emotion recognition test with and without eye-tracking and Cognitive Emotion Regulation. Questionnaire (CERQ)
- Where
- France
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Huntington Disease, Autobiographical Memory
Autobiographical Memory, Future Thought, and Eye Movements in Huntington's Disease
Huntington's disease (HD) is a hereditary neurodegenerative disorder characterized by progressively worsening motor, cognitive, psychiatric, and behavioral deficits.
- Trial name
- MAMOC-MH (NCT07409597)
- Testing
- neuropsychological tests, Eye tracker use
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Healthy Volunteers
Intraosseous Doppler Ultrasonography to Study Skeletal Physiology: Exploratory Study Before Use in Space Physiology
Use of intraosseous Doppler ultrasonography to study skeletal physiology ("Echo-Os Study"). Exploratory study before its use in space physiology. Bones have a complex vascular network providing nutrients and oxygen to bone cells.
- Trial name
- Echo-Os (NCT06206031)
- Testing
- Intraosseous ultrasonography at tibia before, during, and after a physiological vascular stimulation (venous occlusions, arterial occlusion, handgrip)
- Where
- 2 sites in France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Acute Myeloid Leukemia, Hodgkin's Lymphoma
Evaluation of Chemotherapy-induced Cognitive Disorders During the Treatment of Hematological Malignancies
Chemotherapy-induced cognitive disorders, such as memory problems, slowness of execution, inability to concentrate, and language difficulties, are sequelae that occur in patients undergoing chemotherapy or who have received…
- Conditions
- Acute Myeloid Leukemia, Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma
- Trial name
- HematoBrain (NCT07147621)
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Dysautonomia, ACCUVEIN
Screening for Alterations in the Autonomic Nervous System
Dysautonomia is an alteration of the autonomic nervous system that manifests itself in different forms, some of which are very disabling. Dysautonomia accompanies many pathologies.
- Conditions
- Dysautonomia, ACCUVEIN, Superficial Veins, Sympathetic Nervous System
- Trial name
- SYMPA-VEIN (NCT07029191)
- Testing
- Progressive standing test
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Pseudoxanthoma Elasticum, Tomography, Optical Coherence
CHOPXE - Analysis of Choriocapillaris Flow Deficits in Patients With Pseudoxanthoma Elasticum
This observational study sets out to compare choriocapillaris flow deficits between healthy control subjects and patients with pseudoxanthoma elasticum.
- Conditions
- Pseudoxanthoma Elasticum, Tomography, Optical Coherence, Retinal Disease
- Trial name
- CHOPXE (NCT07006649)
- Testing
- Opthtalmologic diagnosis tests
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Medical Student
Impact of Regular Karate Practice on the Quality of Life and Health Outcomes of Students
A recent study reported that 52% of medical students had an anxiety disorder and 18% had a depressive syndrome. Following this publication, the Inspectorate General of Social Affairs commissioned a report on the quality of life…
- Trial name
- KARACADEMIC (NCT07116291)
- Testing
- Karate
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Testicular Positioning Anomalies, Cryptorchidism
Learning to Palpate the Child's Testicles Using Simulation
Hypothesis is that better training of medical students in the examination of boy's external genitalia could improve the diagnosis of testicular position anomalies.
- Trial name
- PaTenSim (NCT07106502)
- Testing
- testicular palpation training on a mannequin
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Thoracic Outlet Syndrome
Systematic Transcutaneous Oxymetry Use in Thoracic Outlet Syndrome
The measurement of the transcutaneous oxygen partial pressure (TCPO2) at exercise is, to our knowledge, the only method to estimate during the exercise the importance of ischemia segment of limb by segment of limb bilaterally and…
- Trial name
- STOUT (NCT03355274)
- Testing
- Transcutaneous Oximetry, Photopletysmography, Questionnaires of Quality of Life (QoL)
- Where
- France
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Acute Respiratory Failure
Surface Mechanomyography Using a Parasternal Patch to Measure and Detect Respiratory Drive and Effort
Surface mechanomyography (sMMG) has been proposed as a tool to study muscle mechanical activity. sMMG is a noninvasive technique using specific transducers to record muscle surface oscillations due to mechanical activity of the…
- Trial name
- PATCH-MMG (NCT06046898)
- Testing
- non-invasive ventilation with or without resistance
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Breast Asymmetry, 3D
MEasurement by a Numerical Approach of BREAst Volume
Breast asymmetry is a rare in plastic surgery. In majority of cases, it is idiopathic. In cases that are poorly tolerated physically (vertebral imbalance, posture disorders) or psychologically, the decision to perform breast…
- Trial name
- MENABREA (NCT03715738)
- Testing
- arm 1 : Creaform3D + MyotonPRO
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Charcot-Marie-Tooth Disease Type 2A
Metabolomic Exploration of Dysregulated Lipid Metabolism in MFN2-related CMT2A (MetaDLM_CMT2A)
Charcot-Marie-Tooth (CMT) disease is the commonest sensitivo-motor inherited peripheral neuropathies with a prevalence of about 10-30 per 100,000. To date, more than 80 genes have been found responsible for CMT.
- Trial name
- NCT04881201
- Testing
- blood sample
- Where
- France
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers