Clinical trials: sponsored by University of British Columbia
Healthy
Fetal Aortic Pulsewave Velocity: A Novel Doppler Ultrasound Method of Measuring the Biophysical Properties of the Fetal Aorta
We are interested in determining if we can measure the blood flow in the descending aorta (large blood vessel in the abdomen) of healthy fetuses and fetuses with growth restriction. An increasing number of adult diseases (e.g.
- Trial name
- NCT00359034
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of British Columbia
Bipolar Depression
RU-486 in the Treatment of Bipolar Depression
Bipolar disorder is a chronic and recurrent illness which involves episodes of mania and depression. It is believed that disturbance of the stress hormone system (the hypothalamic-pituitary-adrenal or HPA axis) may cause thinking…
- Trial name
- NCT00359125
- Testing
- mifepristone (RU-486)
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of British Columbia
Pain
Efficacy of Ametop Cream in Reducing Pain of Local Anesthetic Infiltration
Ametop is a numbing cream used to ease the pain of having blood drawn or an IV inserted. It is safe and virtually none enters the blood stream.
- Trial name
- Ametop (NCT01864213)
- Testing
- Ametop cream
- Where
- Canada
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pain
Trial of Mannitol Cream for Pain Relief After a Long Run
Mannitol cream has been shown clinically to be effective for pain control. To determine if this effect is worth testing on a larger scale, 170 runners will receive a sample of 25% mannitol cream to apply on one leg, and the cream…
- Trial name
- PainCream (NCT01843088)
- Testing
- Mannitol cream
- Where
- Canada
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Influenza Vaccination in Seniors
Enhancing Influenza Vaccination in Seniors With TLR (Toll Like Receptor) Agonists
The application of the TLR7/8 (Toll Like Receptor) agonist gel (immune response helper) resiquimod will enhance the immune response to the intradermal influenza vaccine in seniors 65-75 years of age.
- Trial name
- NCT01737580
- Testing
- resiquimod
- Where
- Canada
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Diabetic Retinopathy
Trientine Hydrochloride for the Prevention of Macular Edema Associated With Pan-retinal Photocoagulation for Severe Non-proliferative and Proliferative Diabetic Retinopathy
To evaluate the effects of Trientine Hydrochloride in prevention of post-laser (pan-retinal photocoagulation) macular edema in the eyes for subjects with diabetic retinopathy.
- Trial name
- NCT01213888
- Testing
- Trientine Hydrochloride
- Where
- Canada
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Colonic Neoplasia
Computed Tomography (CT) Colonography Versus Optical Colonoscopy
This study is designed to compare traditional Colonoscopy with CT Colonography, commonly known as "virtual colonoscopy". The study will compare the ability of both procedures as screening tests to identify polyps in the colon in…
- Trial name
- NCT01181739
- Where
- 2 sites in Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Obesity, Heart Diseases
The Effect of Xenical on Weight and Risk Factors
The purpose of this study is to determine the effect of using the weight loss medication Xenical (generic name - orlistat) on weight loss and change in heart disease risk factors in patients of the Healthy Heart Program Lipid…
- Trial name
- NCT00152360
- Testing
- Orlistat
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Healthy Runners
Footwear Minimalism Study
The following study proposes to investigate the injury risk associated with the use of a new category of running footwear: the minimalist shoe.
- Trial name
- NCT01334346
- Testing
- Nike Pegasus, Nike Free 3.0, Vibram Five Fingers Shoe
- Where
- Canada
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Attention-Deficit/Hyperactivity Disorder (ADHD)
Evaluating Clinical Outcomes of Treatment Effectiveness for Children and Adults With ADHD
To evaluate clinical effectiveness of medication treatment for ADHD. It is hypothesized that the effectiveness is lower than efficacy outcomes measured in clinical trials
- Trial name
- NCT00307268
- Where
- Canada
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Hypotension, Cesarean Delivery
Can Augmentation Index (AIx) be Used to Predict Hypotension After Spinal Anesthesia?
A fall in blood pressure (hypotension) occurs in one third of spinal anesthetics administered to pregnant patients undergoing cesarean delivery.
- Trial name
- NCT00884026
- Testing
- AIx measurement with a Sphygmacor TM
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Cesarean Delivery
Comparing 2 Types of Pain Relief After Cesarean Delivery: Spinal Morphine and TAP Block
Summary Brief Summary Standard care for pain relief after cesarean delivery is spinal morphine. Spinal morphine may be unsuitable for patients having general anesthetic or prior morphine-related side effects and can be less…
- Trial name
- NCT00799955
- Testing
- Ultrasound-guided TAP block
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Oxidative Stress
Lithia Water Study: Effects of Lithia Water on BDNF and Oxidative Stress Markers in Healthy Male Participants
This study investigates the effects of daily use of lithia water on blood tests of neuronal oxidative stress, mood, and well-being.
- Trial name
- NCT01257867
- Testing
- Lithia water, Natural spring water with negligible lithium levels
- Where
- Canada
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Endothelial Dysfunction, Endothelial Function
Cycling, Air Pollution and Health
Introduction: Cycling is currently promoted at the municipal, provincial and national level as a form of active transportation that increases physical activity while at the same time reducing traffic congestion, traffic-related…
- Conditions
- Endothelial Dysfunction, Endothelial Function, Cardiovascular Physiological Phenomena
- Trial name
- CAPaH (NCT01708356)
- Testing
- Cycling on a residential route
- Where
- Canada
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Cardiovascular Risk Factors
Volunteering and Cardiovascular Risk in Adolescents
This study tested whether getting youth engaged in helping others (volunteering) would benefit youth's physical health. 106 predominantly minority and low socioeconomic status (SES) youth were randomized to either volunteer…
- Trial name
- NCT01698034
- Testing
- Volunteering
- Where
- Canada
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Attention-Deficit/Hyperactivity Disorder
SNAP 25 Gene Study
To enhance our capacity to correctly choose the appropriate medication for ADHD patients on the first try based on the presence of a particular variant of a gene that could be identified on a laboratory test.
- Trial name
- NCT00885560
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Vitamin B12 Deficiency
Relative Bioavailability of Folic Acid and L-5-Methlytetrahydrofolate
Folic acid, a form of the vitamin folate, is added to grain products in Canada to help reduce birth defects. Folic acid is the synthetic form of folate and is very stable (doesn't break down) when added to foods.
- Trial name
- NCT01584050
- Testing
- L-5-methyltetrahydrofolate (Metafolin ®), folic acid
- Where
- 2 sites in Canada, Malaysia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Sleep Problems
The Rocky Sleep Study
Night waking with crying can be a distressing and difficult experience for infants and their parents. The investigators want to reduce infant night waking and crying and improve parents' views of their infants' sleep.
- Trial name
- NCT00877162
- Testing
- Controlled crying and routines
- Where
- 5 sites in Canada
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
ACL Injury
Effectiveness of a Novel Warm-up in Decreasing Risk Factors for ACL Injury in Female Youth Soccer Players
There is a large number of young women who sustain serious knee injuries from playing soccer. Female athletes are at high risk of knee injuries from soccer than males.
- Trial name
- NCT01591941
- Testing
- Core-PAC
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Generalized Anxiety Disorder
Efficacy of Treatment for Generalized Anxiety Disorder
The purpose of these questionnaires is to give us an overview of how GAD has affected your life, and perhaps also to give us some clues about things that may have set you up to experience GAD.
- Trial name
- NCT00456742
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of British Columbia