Clinical trials: sponsored by University of Calgary
Anterior Cruciate Ligament Rupture, Deficiency of Anterior Cruciate Ligament
Comparison of Three Methods for Anterior Cruciate Ligament Reconstruction
The purpose of this randomized clinical trial is to determine the difference in quality of life outcome at two years, in patients undergoing an Anterior Cruciate Ligament (ACL) reconstruction procedure with either a patellar…
- Conditions
- Anterior Cruciate Ligament Rupture, Deficiency of Anterior Cruciate Ligament, Chronic Instability of Knee, Anterior Cruciate Ligament Injury
- Trial name
- NCT00529958
- Testing
- Patellar Tendon, Hamstring Tendon, Double-Bundle
- Where
- Canada
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Violence, Gender-Based
Evaluation of the WiseGuyz Program for Adolescent Boys
Adolescent dating violence (ADV) is a pressing public health problem in North America, and strategies to prevent perpetration are needed.
- Trial name
- NCT03994016
- Testing
- WiseGuyz
- Where
- Canada
- Volunteers
- 437 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Bone Loss, Bone Loss, Age-related
Strength Training for Osteoporosis Prevention During Early Menopause
The goal of this clinical pilot trial is to learn about the feasibility of a high-intensity resistance training intervention in peri- and early menopausal females.
- Conditions
- Bone Loss, Bone Loss, Age-related, Osteoporosis, Musculoskeletal Diseases
- Trial name
- STOP-EM (NCT05961371)
- Testing
- Resistance Training
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Malaria, Pregnancy Malaria
LAMP Detection of Malaria in PREGnancy (LAMPREG) Trial
Objective: The aim of this study is to evaluate the impact of enhanced malaria cases detection using molecular testing (LAMP) on maternal and infant morbidity and mortality in a prospective study design.
- Conditions
- Malaria, Pregnancy Malaria, Malaria in Pregnancy
- Trial name
- LAMPREG (NCT03754322)
- Testing
- LAMP, Microscopy/RDT
- Where
- 4 sites in Canada, Ethiopia
- Volunteers
- 2,424 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Parent-Child Relations
ATTACH™ Program: Promoting Vulnerable Children's Health at Scale
ATTACH™ is a psycho-educational parenting program, designed with community agencies serving families of preschoolers affected by toxic stress (e.g.
- Trial name
- ATTACH™ (NCT04853888)
- Testing
- ATTACH™ Parenting Program
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Exercise Training
Exercise Frequency During Endurance Training: Cardiorespiratory, Hematological, and Muscle Oxidative Adaptations
The goal of this interventional study is to compare training for different numbers of days each week in healthy, young individuals.
- Trial name
- NCT05908578
- Testing
- High Frequency Exercise Training, Low Frequency Exercise Training
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Depression, Addiction
Adaptation and Pilot Testing of Web and Mobile Interface for the ATTACH™ Intervention
COVID-19 has placed unprecedented strains on parents impacted by toxic stressors (depression, addiction, family violence, and poverty) and reluctant to see mental health-service providers in home/clinic due to fears of infection.
- Conditions
- Depression, Addiction, Domestic Violence, Poverty
- Trial name
- ATTACH™ (NCT04857775)
- Testing
- Attachment and Child Health (ATTACH) Parenting Program
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Mild Dementia, Moderate Dementia
The Effects of a Park Visit Program on Individuals With Dementia and Their Caregivers
The overall goals of our project is to understand the effects of participating in park visits and nature-based activities for people living with dementia and their caregivers.
- Conditions
- Mild Dementia, Moderate Dementia, Alzheimer Disease
- Trial name
- NCT05527587
- Testing
- Nature Connections Intervention
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Asthma, Respiratory Disease
Airway Remodeling and Rhinovirus in Asthmatics
Human rhinovirus is also called the "common cold virus" because it causes at least half of all of the common colds experienced each year.
- Trial name
- ARRA (NCT05775952)
- Testing
- HRV-39
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Depression in Old Age, Depression, Anxiety
Internet Delivered Psychotherapy for Older Adults
The goal of this mixed-methods, single-arm intervention study is to develop and evaluate a new internet-delivered psychotherapy option called Ger-iPST in older adults with symptoms of depression.
- Trial name
- NCT05739370
- Testing
- Problem-Solving Therapy for Older Adults
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Constipation, Diarrhea
A Novel Iron Supplement for Athletes: Phase I
Female endurance athletes are susceptible to iron deficiency and this can impact their exercise performance. This study is a pilot trial to assess the tolerability of a novel iron supplement prior to conducting a clinical trial…
- Conditions
- Constipation, Diarrhea, Cramp, Abdominal, Bleeding Gastric
- Trial name
- NCT06285851
- Testing
- FeSC
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Induced; Birth
The REDUCED-I Pilot Trial: REDucing the Utilization of CEsarean Sections With Induction
This pilot project is a randomized controlled trial where induced patients receive an intervention of oxytocin discontinuation once in the active stage of labor (≥6 cm dilation).
- Trial name
- (REDUCED-I) (NCT05037617)
- Testing
- Continuation or discontinuation of oxytocin during the active first stage of labor (≥6 cm dilation).
- Where
- Canada
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Occipital Neuralgia, Headache
Ultrasound Guided Platelet Rich Plasma Injections for Post Traumatic Greater Occipital Neuralgia
This study is a randomized controlled trial, assessing the effect of a single platelet rich plasma (PRP) injection in post traumatic (concussive) greater occipital neuralgia.
- Trial name
- NCT04051203
- Testing
- Autologous Platelet Rich Plasma Injection, Depo-Medrol and lidocaine, Normal Saline
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Rotator Cuff Tears
Rotator Cuff Augmentation With Human Dermal Allograft Versus Bovine Collagen Xenograft Patch: A Randomized Controlled Trial
Randomized controlled trial comparing human dermal allograft with bovine collagen xenograft in rotator cuff repair.
- Trial name
- HDA v Regen (NCT06215417)
- Testing
- Rotator cuff repair
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Knee Osteoarthritis
Geniculate Artery Embolization for the Treatment of Knee Osteoarthritis
Osteoarthritis (OA) is a highly prevalent degenerative joint disease that contributes to chronic pain and disability in approximately 10% of people over the age of 55.
- Trial name
- NCT05386797
- Testing
- Geniculate Artery Embolization
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Cicatrix, Hypertrophic
Fractional CO2 Laser Treatment of Hypertrophic Scars
Executive Summary Hypertrophic scars are irregular, raised scars that can cause debilitating symptoms including pain, pruritus, and restricted movement in nearby joints.
- Trial name
- NCT04236167
- Testing
- Fractional CO2 laser treatment -
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Hyperglycemia
PGMP for Alberta Surgical Patients
Patients with postoperative hyperglycemia have higher complication rates and worse outcomes than patients with in-target glucose, including longer length-of-stay, more admissions to intensive care, increased readmission rates…
- Trial name
- NCT05036655
- Testing
- Perioperative glycemic management pathway
- Where
- 2 sites in Canada
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Bronchiectasis, Non-Tuberculous Mycobacterial Pneumonia
Development of a Canadian Bronchiectasis and NTM Database
The investigators aim to develop a comprehensive patient registry of patients with non-CF bronchiectasis and/or Nontuberculosis Mycobacteria (NTM)
- Trial name
- NCT06144996
- Where
- Canada
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Parkinson's Disease and Parkinsonism
Caregiving in Advanced PD: A Tailored Support Group
The goal of this study is to understand how support groups can help people who care for individuals with Parkinson's Disease and Related Disorders (PDRD).
- Trial name
- NCT06074393
- Testing
- Tailored Support Group
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Motor Activity
Repeated iTBS Cycloserine Motor Plasticity
Repetitive transcranial magnetic stimulation (rTMS) is a modality for probing and altering brain function in humans non-invasively.
- Trial name
- NCT05081986
- Testing
- Transcranial Magnetic Stimulation, Cycloserine
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Calgary