Clinical trials: sponsored by University of Colorado, Denver
Epilepsy
Cannabidiol (CBD) and Pediatric Epilepsy
Legislation to allow medical marijuana has had a significant impact on the pediatric population of Colorado. There have been many reported different effects and properties of each of the over 60 known cannabinoids found in…
- Trial name
- NCT02447198
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
HPV Vaccination Decision Quality
Educational Intervention to Improve HPV Vaccination Decision Quality
The purpose of this study is to evaluate an innovative approach to improving HPV vaccination among the Hispanic population. The objectives/aims of this HPV educational intervention project are: 1.
- Trial name
- NCT02797054
- Testing
- Tailored educational materials, Untailored educational materials, Usual care
- Where
- United States
- Volunteers
- 1,205 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Dental Caries
Microbial Testing for Caries Risk Assessment
Specific Aims 1) Assess CG (Cariogenic) Saliva-Check Mutans® saliva testing for identification of high caries risk patients
- Trial name
- NCT03389373
- Testing
- GC Strep Mutans Saliva Sampling
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Pregnancy Related, Sleep Disordered Breathing
The Sleep in Pregnancy Study
Sleep disordered breathing (SDB) insidiously worsens metabolic function, heightens insulin resistance (IR), and in pregnancy is thought to precipitate gestational diabetes, preterm birth, growth restriction, gestational…
- Conditions
- Pregnancy Related, Sleep Disordered Breathing, Obesity
- Trial name
- SiP (NCT03248219)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Headache, Migraine
Adolescents With Migraine: What's Stress Got To Do With It?
The overall objective of this proposal is to better define the relationship between perceived stress, hair cortisol, and migraine in adolescents.
- Trial name
- Adostress (NCT02259387)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Food Allergy, Wheat Allergy
Evaluation of Potential Allergenicity of New Wheat Varieties
The goal of the study is to determine accurate blood test levels that can predict whether or not subjects are truly allergic to certain foods.
- Trial name
- NCT02341040
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Micronutrient Deficiencies
Effect of Sprinkles With and w/o Fe on Zn Absorption in Kenyan Toddlers
The investigators propose to study the effects of increased iron intake by home fortification of complementary foods on the gastrointestinal microbial development, inflammatory responses, and zinc (Zn) absorption.
- Trial name
- NCT02101723
- Testing
- MNP + Zn/Fe, MNP + Zn
- Where
- 2 sites in United States, Kenya
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Varicella, Transplants
Response and Clearance of Viral DNA Following Administration of Live Attenuated Varicella Vaccine.
Varicella zoster virus (VZV) can lead to significant morbidity and mortality in transplant recipients. Current recommendations suggest a 4 week waiting period between vaccination and transplantation and consideration of booster…
- Trial name
- NCT02692066
- Testing
- varicella vaccine
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Suicide and Self-harm
Home-Based Mental Health Evaluation (HOME)
The purpose of this project is to investigate the effectiveness of the Home-Based Mental Health Evaluation (HOME) program, which is an innovative and culturally-relevant suicide prevention intervention for Veterans aimed at…
- Trial name
- HOME (NCT03347552)
- Testing
- HOME
- Where
- 3 sites in United States
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Osteoporosis
PTH And Calcium Responses to Exercise (PACE) in Older Adults
Exercise that causes a decline in serum Calcium (Ca) as a result of dermal Ca loss stimulates bone resorption via an increase in Parathyroid Hormone (PTH).
- Trial name
- NCT02468817
- Testing
- Treadmill Exercise, Magnitude of Ca loss during Exercise at 26 degrees Celcius
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Chronic Kidney Disease
Endothelial Microparticles: A Novel Marker of Vascular Dysfunction
The primary hypothesis of this proposal is that chronic kidney disease (CKD) and treatment with calcineurin inhibitors (CNIs) are each associated with the release of endothelial microparticles into the plasma.
- Trial name
- NCT02230202
- Testing
- Flow-mediated dilation, single blood draw
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
COPD, Cystic Fibrosis
Autologous CD117+ Progenitor Cell Mobilization for Lung Transplantation
The purpose of this study is to determine if the drug Plerixafor (Mozobil) can lead to clinically relevant efflux of CD117+ stem cells from the bone marrow to the peripheral blood of normal controls and patients awaiting lung…
- Conditions
- COPD, Cystic Fibrosis, Pulmonary Fibrosis
- Trial name
- NCT01916577
- Testing
- Plerixafor mobilization of autologous CD117 stem cells
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Oxidative Stress
Normal Values of Oxidative Stress, Taurine, and Related Markers
The role of oxidative stress in disease pathology is increasingly recognized. At present, the development of biomarkers of this state is in its infancy and the availability of clinically validated assays is lacking.
- Trial name
- NCT02649777
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Rheumatoid Arthritis, Periodontal Disease
Periodontal Inflammation and Immunity in Preclinical Rheumatoid Arthritis
The purpose of this study is to evaluate the association of Rheumatoid Arthritis (RA)-related antibodies and periodontal inflammation in subjects at-risk for Rheumatoid Arthritis.
- Trial name
- NCT02794012
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Hematopoietic/Lymphoid Cancer
Improved Outcome in Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Patients by Reducing Caregiver Distress
PURPOSE: As this is a randomized controlled trial, all subjects receiving stress management psychoeducation will be expected to obtain a new set of coping skills that will allow them to better deal with the stressors of…
- Trial name
- NCT02037568
- Testing
- fPER
- Where
- 2 sites in United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Human Immunodeficiency Virus (HIV)
Shedding, Immunogenicity and Safety of Quadrivalent Live Intranasal Influenza Vaccine (QLAIV) in HIV-infected Children and Young Adults
The goal of this study is to determine if there is a difference in shedding (primary objective) and in immunogenicity and safety (secondary objectives) between HIV-positive and HIV-negative children and young adults who are…
- Trial name
- QLAIV (NCT02474901)
- Testing
- Quadrivalent Live Attenuated Influenza Vaccine
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Growth, Body Composition
How Infant Diets Would Affect Growth in Early Childhood
The investigators research group conducted a feeding study in 2012 (IRB 07-0003) that included breastfed infants consuming different infant solid foods.
- Conditions
- Growth, Body Composition, Gut Health
- Trial name
- FYI-FU (NCT02440503)
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Healthy, Volunteers
Effects of Testosterone and Fat Utilization
Evidence is accumulating that there are sex differences in energy and substrate metabolism. The positive or negative consequences of such metabolic differences between men and women need to be evaluated with respect to health…
- Trial name
- NCT03289559
- Testing
- GnRH antagonist, Aromatase Inhibitors, Testosterone gel
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Pregnancy
Partnership to Improve Nutrition and Adiposity in Prenatal Clinical Care: a Pilot and Feasibility Study
This study will pilot and assess feasibility of a prenatal intervention for obese pregnant women based on the Diabetes Prevention Program (DPP).
- Trial name
- NCT02520167
- Testing
- Dietary and Lifestyle Counseling
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Fatigue
Impact of Transcranial Direct Current Stimulation on Fatigability and Fatigue Induced by a Selective Attention Task
This research project is focusing on changes in mental fatigue due to transcranial direct current stimulation (tDCS) in healthy individuals.
- Trial name
- NCT02840214
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Denver