Clinical trials: sponsored by University of Colorado, Denver
HIV Infections
Effect of Antacids on the Pharmacokinetics of Raltegravir
The purpose of this study is to test whether there is a drug interaction between raltegravir (a medicine used to treat the human immunodeficiency virus or HIV) and antacids.
- Trial name
- NCT00944307
- Testing
- raltegravir, antacid
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
HPV Vaccination Status
Educational Intervention to Minimize Disparities in Humanpapillomavirus Vaccination
The purpose of this study is to evaluate an innovative approach to improving HPV vaccination among the Hispanic population. The clinical objectives/aims of this HPV educational intervention project are to determine: 1.
- Trial name
- HPV (NCT02145156)
- Testing
- Tailored educational materials, Untailored educational materials, Survey-only
- Where
- United States
- Volunteers
- 1,294 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Colon Cancer
Simultaneous Improvement in Colon Cancer Screening Rates and Patient-Centered Care
Several screening methods exist to screen patients for CRC ranging from invasive (i.e., colonoscopy) to less invasive (i.e., testing the stool for blood).
- Trial name
- CRCSreening (NCT02377232)
- Testing
- Decision Aid for Colon Cancer Screening, Usual Care Outreach for Colon Cancer Screening
- Where
- United States
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Type 1 Diabetes
Primary Intervention With Mucosal Insulin
A dose with proven drug bioavailability to the immune system for use in a phase II/III primary T1DM (type 1 diabetes) vaccination trial (POINT study) in genetically at risk subjects.
- Trial name
- Pre-POINT (NCT02620553)
- Testing
- Human Insulin
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Obesity
The Effects of Energy Imbalance on Food Intake Behaviors
This study will determine whether changes in energy balance alter regional neuronal activation of brain regions associated with food intake in individuals screened to be either resistant or prone to obesity.
- Trial name
- NCT03112161
- Testing
- Eucaloric Feeding Period, Overfeeding Feeding Period, Underfeeding Feeding Period
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Breast Cancer, Leukemia
Delayed Effects of Treatment in Cancer Survivors (DETECS)
Hypotheses and Specific Aims: There is limited data on the long-term consequences of cancer therapy on young, reproductively aged cancer survivors.
- Conditions
- Breast Cancer, Leukemia, Lymphoma, Gynecologic Cancer
- Trial name
- DETECS (NCT02067637)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Influenza
Influenza Immunization of Children in India
Influenza viruses are significant causes of human illness and death in developed and developing countries. This study will measure the ability of influenza vaccine given to children in India to protect both the children and…
- Trial name
- NCT01680679
- Testing
- Inactivated Trivalent Influenza Vaccine (TIV), Inactivated poliovirus vaccine (IPV), trivalent
- Where
- India
- Volunteers
- 18,163 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Competency-Based Education
Rapid Assessment of Trainee Endoscopy Skills (RATES) Study
The establishment of a number of training programs in therapeutic endoscopy, standardization of the performance of endoscopic ultrasound (EUS) and endoscopy retrograde cholangiopancreatography (ERCP) and definition of competence…
- Trial name
- RATES (NCT02247115)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Marfan Syndrome, Loeys-Dietz Syndrome
Micro RNAs as a Marker of Aortic Aneurysm in Hereditary Aortopathy Syndromes
The primary objective of this study is to determine whether specific patterns of circulating micro-ribonucleic acids (miRNAs) are associated with aortic aneurysm and dissection in patients with hereditary aortopathy syndromes.
- Conditions
- Marfan Syndrome, Loeys-Dietz Syndrome, Thoracic Aortic Aneurysm and Dissection Syndromes, Ehlers-Danlos Type IV Syndrome
- Trial name
- NCT02213484
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Behavior, Adaptive
The Prenatal/Early Infancy Project: An Adolescent Follow-up
The Nurse-Family Partnership, a program of prenatal and infancy home visiting by nurses, has been examined in a series of 3 randomized trials since 1977.
- Trial name
- NCT03079752
- Testing
- Developmental Screening, Screening plus Transportation, Screening, Transport, Prenatal Visits
- Volunteers
- 629 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Altitude Sickness
Inhaled Budesonide for Altitude Illness Prevention
A randomized, double-blinded study administering budesonide, a medication to reduce inflammation in the lungs, to healthy volunteers to examine effects on altitude illness prevention by spending 18 hours overnight at 14,000 ft…
- Trial name
- NCT02941510
- Testing
- Budesonide
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Contraception
Intra Uterine Device Insertion in Nulliparous Women
Over the last several years, more and more women are choosing intrauterine contraception (IUDs) to meet their birth control needs.
- Trial name
- NCT01422226
- Testing
- Misoprostol
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Obesity, Fertility
Effects of Dietary Omega-3 Fatty Acids on Reproductive Hormones in Obese Women
The United States has the highest prevalence of obesity among all countries surveyed in 2012 by the Organization for Economic Cooperation and Development.
- Trial name
- NCT01894581
- Testing
- LOVAZA, GnRH
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Levels of Pain
Effect of Low Level Laser Therapy on Pain Induced by Placement of Orthodontic Separators in Pediatric Patients
The primary goal of the study is to determine if there is a difference in pain levels following the use of low level laser therapy versus placebo and control after placement of elastomeric orthodontic separators in pediatric…
- Trial name
- NCT02211547
- Testing
- Epic 10 Diode Laser by Biolase Inc.
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
HIV Infections
Reduction of Drug Use and HIV Risk Among Out-of-Treatment Methamphetamine Users
There is a need to identify and test effective strategies to reduce meth use and human immunodeficiency virus (HIV) risk behaviors in heterosexuals.
- Trial name
- NCT01161485
- Testing
- HIV Testing and Counseling, Contingency Management, Strengths-based case management
- Where
- United States
- Volunteers
- 502 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Healthy Children
Parental Views Related to Colorado State Legislation About Vaccinations, Schools, and Child Care Centers
Through an online survey, participants will be shown different visual presentations of vaccination data related to schools and child care centers.
- Trial name
- NCT02957344
- Where
- United States
- Volunteers
- 679 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Obesity
Reproductive Hormonal Alterations in Obesity
The purpose of this study is to determine why obese women have lower hormone levels and less fertility than women of normal body weight.
- Trial name
- NCT01457703
- Testing
- Cetrorelix, Gonadorelin-GnRH, Recombinant LH
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Menopause, Pre-menopause
Following Lipectomy to Understand Adipose Tissue Re-accumulation
The typical female pattern of accumulating fat in the hips and thighs has long been thought to confer less risk for disease than the typical male abdominal fat pattern.
- Trial name
- FLARE (NCT00995631)
- Testing
- Femoral lipectomy
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Schizophrenia
Phase I Study to Evaluate the Safety and Pharmacokinetics of Oral Doses of Anvylic-3288 in Healthy Subjects
This is a brief inpatient study to determine the safety of a new drug in healthy people.
- Trial name
- AVL3288 (NCT01851603)
- Testing
- AVL-3288
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Disproportionate Shape, Expanded Fat Pads
Mechanisms Defending Fat Mass in Humans After Lipectomy
Liposuction surgery is common, yet animal and limited human data suggest that fat returns when removed. This study was designed as a 1-year randomized-controlled trial of suction lipectomy versus no intervention to determine if…
- Trial name
- NCT00993213
- Testing
- Standard of Care with Liposuction, Standard of Care without Liposuction
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver