Clinical trials: sponsored by University of Massachusetts, Worcester
Pre-Exposure Prophylaxis
Developing mHealth to Promote PrEP Use Among Thai Young Men Who Have Sex With Men
The goal of this study is to develop and pilot test technology-based interventions to promote Pre-exposure Prophylaxis (PrEP) uptake and adherence among Thai young men who have sex with men (YMSM).
- Trial name
- NCT05243030
- Testing
- Motivational Enhancement System for PrEP Uptake and Adherence (MES-PrEP), Motivational Interactive Text Messaging (MTM), Standard PrEP Counseling
- Where
- 3 sites in Thailand
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Fatigue, Shift Work Type Circadian Rhythm Sleep Disorder
Does Fatigue Coaching Improve Functioning and Fatigue in Resident Night Shifts
Emergency Medicine (EM) requires 24/7 staff coverage resulting in healthcare workers' circadian rhythm disruptions that impair clinical and cognitive performance, physical recovery, and contribute to burnout.
- Trial name
- NCT06100809
- Testing
- Personalized coaching, Nutrition handout
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Wellness, Psychological
Impact of a Virtual Reality-based Mindfulness Program on Clinician Wellness
Burnout shares symptoms with anxiety and depression. While there is no single intervention for burnout, there are validated interventions (which are amenable to virtual reality (VR)) for anxiety and depression.
- Trial name
- NCT06246539
- Testing
- VR mindfulness
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Opioid Abuse (Disorder)
Improving Jail Response to the Overdose Crisis: A Hybrid Trial of Jail ECHO to Improve MOUD Implementation and Public Health Outcomes
This project tests a training strategy to help rural jails start or increase their use of medications to treat opioid use disorder (MOUD - methadone, buprenorphine, naltrexone).
- Trial name
- J-ECHO OPS (NCT07637994)
- Testing
- Project ECHO
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Bladder Perforation, Retropubic Midurethral Sling
Retropubic Hydrodissection and Trocar-induced Bladder Perforation During Retropubic Midurethral Slings
Retropubic midurethral slings are a common and effective treatment for stress urine incontinence. The trocar that is attached to the mesh material can hit the bladder which is called a perforation.
- Conditions
- Bladder Perforation, Retropubic Midurethral Sling, Retropubic Hydrodissection
- Trial name
- NCT07208682
- Testing
- retropubic hydrodissection
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Weight Management Counseling
Medical Residents Learning Weight Management Counseling Skills
The goal of this study is to addresses the lack of weight management training physicians receive during their residency training.
- Trial name
- MRWeight (NCT06529666)
- Testing
- Didatic Session 1: Core Foundation Course, The 3Ps Program, Didactic session 2
- Where
- 8 sites in United States
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Pre-Exposure Prophylaxis
Developing mHealth to Promote PrEP Use Among Thai Young Vulnerable Adolescents and Emerging Adults
The main aim of this study is to develop technology-based interventions to improve HIV pre-exposure prophylaxis (PrEP) uptake and adherence among Thai young transgender women.
- Trial name
- NCT05262426
- Testing
- Behavioral: Motivational Enhancement System for PrEP Uptake and Adherence (MES-PrEP), Enhanced YaCool, Standard PrEP Counseling
- Where
- 3 sites in Thailand
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Pre-Exposure Prophylaxis
Zambia Healthy Choices Project for Emerging Adults Living With HIV
This project will develop and implement a multi-component intervention using mobile health technology to improve HIV self-management and reduce substance use.
- Trial name
- NCT06415357
- Testing
- Mobile Healthy Choices (mHC), Motivational Text Messaging (MTM), Standard ART Counseling
- Where
- Zambia
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Cancer, Cardiovascular Diseases
ActivityChoice: Implementing Clinic-Based Physical Activity Program Choices for Cancer Survivors
Cardiovascular disease, the number one leading cause of death in the United States, is highly prevalent in cancer survivors. Physical activity can reduce risk, and referrals to programs addressing survivors' choices are highly…
- Conditions
- Cancer, Cardiovascular Diseases, Physical Inactivity
- Trial name
- NCT05870176
- Testing
- Enhanced Referral, Standard Referral
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Pre-Exposure Prophylaxis
Thailand HIV and Stigma Reduction Study
This project will develop a multi-component, technology-delivered intervention designed to reduce HIV and intersectional stigma and improve the use of HIV pre-exposure prophylaxis (PrEP) among HIV-negative Thai vulnerable…
- Trial name
- NCT06576648
- Testing
- Mobile Healthy Choices (mHC), Finding Respect and Ending Stigma around HIV (FRESH), Standard PrEP Counseling
- Where
- 3 sites in Thailand
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Built Environment
Neighborhood Connect
The study is evaluating the effectiveness of an implementation strategy called Neighborhood Connect, which is designed to support residents' engagement in activities that improve the attractiveness, safety and livability of…
- Trial name
- NCT07780825
- Testing
- Neighborhood Connect
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Pediatric Delirium
Pediatric Delirium
Preventing emergent delirium in pediatric ambulatory surgery through preoperative use of intra-nasal Dexmedetomidine and oral Midazolam.
- Trial name
- NCT04669457
- Testing
- Intra-nasal Dexmedetomidine, Oral Midazolam
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Vaccination, Vaccination Promotion
ARISe at UMass Chan
The goal is to identify the most impactful strategies for capturing attention and enhancing effectiveness of vaccine promotion messages.
- Trial name
- ARISe (NCT07236034)
- Testing
- Exposure to source and message content
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Tobacco Cessation
Tobacco Cessation Texting Intervention for People Living With HIV Who Smoke in Vietnam
The intersection of smoking and HIV/AIDS poses a serious public health threat in Vietnam. Vietnam is dealing with these two challenges with parallel rather than integrated plans.
- Trial name
- M2Q2-HIV (NCT05863923)
- Testing
- mHealth Messaging to Motivate Quitline use and Quitting among Persons Living With HIV (PLWH) in Vietnam (M2Q2-HIV), M2Q2-HIV Comparison
- Where
- 2 sites in United States, Vietnam
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
COPD, Early-Onset
SPIROMICS Study of Early COPD Progression (SOURCE)
This is an observational study of 1000 participants to further define the nature of early chronic obstructive pulmonary disease (COPD) in younger, at-risk individuals.
- Trial name
- SOURCE (NCT05033990)
- Where
- 14 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Hyperlipidemias, Diabetes
Social Needs Screening and Chronic Diseases Study (WE CARE)
The goal of this clinical trial is to learn if the implementation of the WE CARE social determinants of health (SDOH) screening and referral intervention with an antiracist lens in primary care settings can lead to a meaningful…
- Conditions
- Hyperlipidemias, Diabetes, Depression, Pediatric Asthma
- Trial name
- NCT06903897
- Testing
- WE CARE SDOH System, Standard Pediatric Care
- Where
- 3 sites in United States
- Volunteers
- 68,000 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Safe Sleep Education, SUID
Social Media and Risk-reduction Training for Preterm Infant Care Practices
SMART Preemie is a cluster randomized trial that will investigate the effectiveness of NICU-based and post-discharge interventions to improve adherence to safe sleep practices among mothers of preterm infants.
- Conditions
- Safe Sleep Education, SUID, Sudden Infant Death Syndrome (SIDS)
- Trial name
- SMART Preemie (NCT07420686)
- Testing
- Safe Sleep NICU Quality Improvement Campaign, Shared Reading NICU Quality Improvement Campaign, Safe Sleep TodaysNICUBaby videos and messages
- Where
- United States
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Hemorrhagic Stroke, Intracerebral, Acute Ischemic Stroke
Feasibility of a Digital Goals-of-Care Decision Aid for Clinicians and Families of Patients With SABI
The goal is to pilot test a highly accessible, web-based, pragmatic, scalable intervention to overcome ongoing problems with high stakes decision-making by surrogate decision-makers of patients in ICUs with severe acute brain…
- Conditions
- Hemorrhagic Stroke, Intracerebral, Acute Ischemic Stroke, Traumatic Brain Injury
- Trial name
- NCT05671874
- Testing
- Web/mobile/tablet-based digital decision aid + communication (DA+C) tool
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Dental Caries, Obesity Risk
Mothers' Action Project for Child Health
This randomized controlled trial will recruit Bangladeshi mothers and their young children into a 12 month intervention that provides child health and oral health education and seeks to build social networks among mothers.
- Trial name
- MAP-CH (NCT06753669)
- Testing
- health education and social network building, dental referral and educational materials
- Where
- United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Cholecystitis
Prospective Evaluation of an Endoscopic Ultrasound (EUS)-Based Artificial Intelligence to Assist in the Deployment of Lumen Apposing Metal Stents for Gallbladder Drainage
Lumen apposing metal stents are now being used to help patients who suffer from cholecystitis (infection of the gallbladder), especially in cases where patients are not candidates for surgery.
- Trial name
- EUS-AI GBD (NCT06981052)
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester