Clinical trials: sponsored by University of Minnesota
Smoking, Cigarette
Biomarkers of Exposure and Effect in Standardized Research E-cigarette (SREC) Users
This study is focused on characterizing the toxic and carcinogenic potential of the Standardized Research E-cigarette (SREC) developed by the National Institute on Drug Abuse.
- Trial name
- NCT04003805
- Testing
- Standardized Research E-cigarette (SREC)
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Healthy
State Dependence of Prefrontal Transcranial Magnetic Stimulation
The study will examine whether the benefits of brain stimulation on mental functioning can be enhanced if an individual is actively engaging the target brain networks while receiving brain stimulation.
- Trial name
- NCT05962385
- Testing
- Brain state while receiving TMS
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Stroke
Phase-dependent Evaluation of Motor Cortex Excitability With TMS in Stroke
The purpose of this study is to investigate the effects of transcranial magnetic stimulation (TMS) on motor cortex excitability in individuals who have suffered stroke and to study the influence of the phase of the oscillatory…
- Trial name
- NCT04968743
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Dandruff, Seborrheic Dermatitis
Cleansing Device for the Treatment of Scalp and Hair Conditions
The objective of this study is to evaluate an improvement of scalp health after the use of an investigational off-label WaterPik and brush device aimed to massage and cleanse the scalp.
- Conditions
- Dandruff, Seborrheic Dermatitis, Hair Loss
- Trial name
- NCT05319444
- Testing
- Off-brand Waterpik®
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Working Memory
Traveling-wave Transcranial Electric Stimulation
This study will assess the impact of traveling wave transcranial alternating current stimulation (tACS) on working memory performance in adults.
- Trial name
- TravelingTES (NCT05399381)
- Testing
- Transcranial alternating current stimulation (tACS)
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Type2Diabetes
TRE in Type 2 Diabetes (See Food Study 3)
Hyperglycemia in patients with Type 2 Diabetes Mellitus is initially treated with metformin coupled with intentional caloric restriction, which is difficult to sustain due to multiple barriers, including acquiring the necessary…
- Trial name
- SFS3 (NCT05290246)
- Testing
- Time restricted eating, Caloric reduction
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Alzheimer Disease, Dementia
Utilizing Senior Companions to Enhance Dementia Care
The inability of healthcare systems to effectively manage Alzheimer's disease and related dementias (ADRD) often results in families remaining unaware of important community-based, long-term services and supports (LTSS) that…
- Trial name
- NCT03667924
- Testing
- PorchLight Project
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Social Stress, Adolescent Behavior
Neural Correlates of the Shift in Social Buffering of Social Evaluative Threat
The purpose of this experiment is to determine the mechanisms through which parental buffering of stress physiology in response to social evaluative threat diminishes with pubertal development and whether this diminution of…
- Trial name
- NCT04211155
- Testing
- Questionnaires, MRI
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Self-Injurious Behavior, Deliberate Self-Harm
A Study Examining Adolescents With Non-Suicidal Self-Injury
This study will examine longitudinal brain development in young adolescent girls with a history of Non-Suicidal Self-Injury (NSSI).
- Trial name
- RDoC (NCT02947308)
- Where
- 3 sites in United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Suicide, Attempted, Suicide, Ideation
Teen Brain Training (TBT)
A non invasive treatment study including participants at risk for suicide attempts and undergoing neurofeedback training. Neurofeedback is controlling your brain activity in real time inside the scanner.
- Conditions
- Suicide, Attempted, Suicide, Ideation, Depression
- Trial name
- NCT06183580
- Testing
- neurofeedback training involving dACC, neurofeedback training involving amygdala
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Tobacco Use
Sugars in Cigarettes
The aim of this study is to investigate the impact of sugar levels in cigarette tobacco on cigarette abuse liability and appeal.
- Trial name
- NCT05308316
- Testing
- Cigarettes with added sucrose
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Behavior Problem, Behavior, Child
Effectiveness of an Online Parenting Training
Child and adolescent behavioral health problems are related to the leading causes of youth morbidity and mortality. Parent-focused preventive interventions, such as GenerationPMTO (GenPMTO), effectively prevent behavioral health…
- Conditions
- Behavior Problem, Behavior, Child, Parents, Parent-Child Relations
- Trial name
- NCT05111886
- Testing
- Communication Skills Training, eHealth GenPMTO, Written Referral Process
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Social Stress, Adolescent Behavior
Affective Social Buffering
The purpose of this experiment is to determine the mechanisms through which parental buffering of stress physiology during affective stimulus presentation diminishes with pubertal development and whether this diminution of…
- Trial name
- NCT04312945
- Testing
- Questionnaires, MRI
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Approach/Avoidance Behavior
Theta Phase-specific TMS to Modulate Prefrontal Activity
The purpose of this study is to evaluate the causal link between the phase of ongoing theta oscillations in the prefrontal cortex and approach/avoidance (Ap/Av) behavior in adults using theta phase-specific transcranial magnetic…
- Trial name
- NCT05416138
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Healthy
Clinical Trial of Two Study Drinks in Detoxification of Environmental Toxicants and Carcinogens
The goal of this research is to determine if consuming one of two study drinks will help enhance the detoxification of multiple environmental toxicants and cancer causing agents, particularly in subjects who are null for…
- Trial name
- NCT03978117
- Testing
- Freeze Dried Watercress Preparation
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Yellow Fever
The Effect of Inflammation and Damage to Lymph Node Structures on Durable Protective Immunity Following Yellow Fever Vaccination
Hypothesis: Infections other than HIV can cause LN inflammation and collagen damage to the fibroblastic reticular cell network (FRCn), which will lead to CD4 T cell depletion and impaired vaccine responses.
- Trial name
- NCT04269265
- Testing
- Yellow Fever Vaccine
- Where
- 2 sites in United States, Uganda
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smoking
Metabolism of NNK in Japanese Americans
The risk of lung cancer varies by individual and by ethnic/racial group. In this study the investigators will explore how individual differences in the metabolism of a tobacco-specific lung carcinogen may contribute to the…
- Trial name
- NCT04228952
- Testing
- Modified Natural American Spirit-Tan or Green cigarettes injected with labeled NNK
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Perception Disturbance, Visual Suppression
Visual Surround Suppression and Perceptual Expectation Under Psilocybin
The prospective pilot study will address the critical need for more precise characterizations of the acute visual effects of the drug psilocybin by measuring the impact of acute psilocybin intoxication on a perceptual task known…
- Conditions
- Perception Disturbance, Visual Suppression, Psychedelic Experiences
- Trial name
- NCT04424225
- Testing
- Psilocybin, Niacin
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Tobacco Use
Telehealth-Filter Ventilation ( COMET2P1 )
The goals of this project are to determine the effects of varying degrees of cigarette filter ventilation on biomarkers of toxicant exposure and smoking behavior and on subjective responses to the cigarette.
- Trial name
- NCT04969783
- Testing
- Ventilated Cigarette Filter, Unventilated Cigarette Filter
- Where
- 2 sites in United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Spasmodic Dysphonia
Laryngeal Vibration for Spasmodic Dysphonia
The general aim of the research is to provide scientific evidence that vibro-tactile stimulation (VTS) represents a non-invasive form of neuromodulation that can induce measurable improvements in the speech of people with…
- Trial name
- SD-VTS (NCT03746509)
- Testing
- Laryngeal Vibration (Treatment), Laryngeal Vibration (Comparator)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Minnesota