Clinical trials: sponsored by University of Oklahoma
Brain Aging, Cerebrovascular Function
AKG and Brain Health in Aging
This proposal will test the hypothesis that AKG supplementation will improve NGVC responses and cognitive performance in older adults.
- Trial name
- NCT07861867
- Testing
- Calcium AKG
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Colorectal Cancer (CRC)
Raising Awareness of Colorectal Screening in American Indian Communities
This study focuses exclusively on American Indian individuals within their communities to enhance health equity and address a critical tribal health priority.
- Trial name
- AIC-DC (NCT07515729)
- Testing
- Navigator-led intervention
- Volunteers
- 446 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Smoking Cessation
Trial of Varenicline With Nicotine Lozenges and a Smartphone Medication Adherence Intervention for Smoking Cessation
No published studies to date have evaluated the combined impact of varenicline and oral nicotine replacement therapy (NRT) on smoking cessation in a randomized trial.
- Trial name
- COMBOII (NCT07099638)
- Testing
- Varenicline (VAR), Nicotine lozenge (NRT), Smartphone intervention with adherence components (COMBO-A)
- Where
- United States
- Volunteers
- 496 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Time Restricted Eating
Cerebromicrovascular Effects of Time-Restricted Eating in Older Adults
The central hypothesis of this study is that closer adherence to time restricted eating (TRE) will improve endothelial function, neurovascular (NVC) responses, resulting in improved cognitive performance, potentially through…
- Trial name
- NCT05488652
- Testing
- Time restricted eating
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Elbow Fractures
Efficacy of the Buzzy System on Pain and Fear Reduction in Elbow Fracture Pin Removal
The goal of this study is to determine if the Buzzy System, a vibrating ice pack shaped like a bee reduces pain in removal of elbow fracture pin.
- Trial name
- NCT07520851
- Testing
- Flash Cards, Buzzy Ice pack
- Where
- 2 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Impact of Supervision on Endoscopy Simulation Curriculum
Outcomes in Simulated Endoscopy Training
Eligible participants are those who are members of the general surgery residency pediatric gastroenterology fellowship, and adult gastroenterology fellowship.
- Trial name
- NCT03495141
- Testing
- Supervision/Coaching
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Pancreas Cancer, Hepatocellular Carcinoma
Analysis of Breath Volatile Organic Compounds Using Mass Spectrometry
The purpose of this clinical trial is to evaluate whether volatile organic compound (VOC) signatures detected in the breath of patients with cancer can serve as a potential screening tool for the early detection of cancer.
- Conditions
- Pancreas Cancer, Hepatocellular Carcinoma, Lung Cancer, Ovarian Cancer
- Trial name
- NCT07732686
- Testing
- Proton Transfer Reaction Mass Spectrometry Analysis
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Postural Tachycardia Syndrome
Autoimmune Basis for Postural Tachycardia Syndrome
The purpose of this study is to test the hypothesis that an antibody-mediated autoimmune reaction will cause symptoms of autonomic dysfunction in some patients with postural tachycardia syndrome (POTS).
- Trial name
- NCT05043051
- Testing
- Vagal stimulation
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Smoking Cessation
Mobile Contingency Management for Smoking Cessation
The purpose of the proposed project is to evaluate an automated mobile phone-based CM approach that will allow socioeconomically disadvantaged individuals to remotely benefit from financial incentives for smoking cessation.
- Trial name
- P3 (NCT04881630)
- Testing
- Automated Mobile Contingency Management (CM), Standard Care (SC)
- Where
- United States
- Volunteers
- 532 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Diet Habits, Cancer Prevention
Dietary Fiber and Time Restricted Eating
This study is seeking to examine combinations of two different dietary interventions on cancer risk.
- Trial name
- FIBER+TRE (NCT07219706)
- Testing
- Time Restricted Eating, Group education, Counseling
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Missing Teeth
Osseodensification and Implant Survival and Success
Approximately 40 implants from patients seeking treatment at the University of Oklahoma, College of Dentistry will be recruited for this study.
- Trial name
- NCT04741594
- Testing
- Densah
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
AI-assisted Colonoscopy
AI_Colonoscopy_for_Fellows
The goal of this study is to look at how good artificial intelligence (AI) assisted colonoscopy is compared to conventional colonoscopy in detecting polyps when used by gastroenterology fellows.
- Trial name
- NCT07661914
- Testing
- AI assisted colonoscopy, Conventional Colonoscopy
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Premature Birth
Prophylactic DR-CPAP on Late Preterm Infants Born by C-section: an RCT
A Pragmatic Randomized Controlled Pilot Trial to Evaluate the Impact of Early Prophylactic Continuous Positive Airway Pressure with or without Supplemental Oxygen in Spontaneously Breathing Late Preterm Newborn Infants Born by…
- Trial name
- PLANT (NCT05204719)
- Testing
- Prophylactic Delivery Room Continuous Positive Airway Pressure
- Where
- 5 sites in United States, Canada and 1 more
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Creatine Absorption in Healthy Adults
Acute Pharmacokinetics of Create Wellness Gummies in Healthy Adults
The purpose of this study is to compare blood creatine levels following acute oral supplementation of Create Wellness creatine gummies to creatine monohydrate powder.
- Trial name
- NCT07579455
- Testing
- Create Wellness Creatine Gummies, Creatine Monohydrate Powder
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Nutrition Poor, Health Behavior
Technical Assistance for Child and Adult Care Food Program in Family Child Care Home
This study evaluates the effect of a nutrition technical assistance training program for family child care home providers on the food they serve young children in their care and the food environment in their home.
- Trial name
- NCT03560050
- Testing
- Nutrition assistance, Children's environmental health/comparison
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Cigar Smoking, Tobacco Use
Cigar Legislation and Regulation in Tobacco for the Young (Project CLARITY)
This clinical trial will recruit young adults who currently use cigarillos and examine the smoking behavior and perceptions of different flavored cigarillos, product ingredients/additives impacting these perceptions, and…
- Trial name
- CLARITY (NCT07162935)
- Testing
- Cigarillo brand 1, Cigarillo brand 2, Cigarillo brand 3
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Smoking Cessation
Empowering Cessation ACS South Region
Sexual and/or gender minority (SGM) people face a disproportionate burden of cancer risk, and tobacco use is a key modifiable risk factor.
- Trial name
- CHERC (NCT06820034)
- Testing
- Empowering Cessation for the ACS South
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Smoking Cessation
Developing Empowering Smoking Cessation
Problem: Despite encouraging use declines in the U.S. population, tobacco is still a leading cause of preventable disease and death.
- Trial name
- ECHO (NCT06602076)
- Testing
- ECHO (Empowering Our Community & Health Outcomes)
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Oklahoma
Photophobia
Comparison Between Spectacles and Contact Lenses
Many people suffer from migraine headaches, some more so than others and a common trigger/complaint is light sensitivity, or photophobia1.
- Trial name
- NCT06905912
- Testing
- Biomedics55 Premier contact lenses, and Altius Tinted Contact Lenses
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Healthy
The Effects of Acute Melatonin Supplementation on Cardiovascular Responses to Sympathetic Activation
the purpose of this experiment is to determine if acute melatonin supplementation alters central and peripheral cardiovascular responses to a cold pressor test at rest and during dynamic exercise.
- Trial name
- NCT04831398
- Testing
- melatonin
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma