Clinical trials: sponsored by Uppsala University
Sleep Deprivation, Sleep
Metabolic and Cognitive Parameters Following Partial Sleep Deprivation
The purpose of this study is to determine whether partial sleep deprivation, as compared with normal sleep, influences certain metabolic and cognitive parameters, related to food intake, hunger and memory functions, when…
- Trial name
- NCT01823263
- Testing
- Portion Size Task, Blood sample, Interference task
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Technical Feasibility, Ambulances
Technical Feasibility Study of a Novel Wearable Capnograph (MARIE) in an Emergency Care Environment, Part 1
You have been assessed by paramedics as needing to go to the emergency department. During transport, the paramedics will monitor you by, for example, measuring your blood pressure and checking your pulse.
- Trial name
- MARIE (NCT06905613)
- Testing
- Technical feasibility study of a novel wearable capnograph (MARIE) in an emergency care environment
- Where
- Sweden
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Eating Disorders
Comparing Neural Responses to Food Images in EDNOS Patients and Healthy Controls Using fMRI
Currently, there is not a robust, testable neural model available that sufficiently explains the development and maintenance of anorexia nervosa (AN) a severe, often fatal, adolescent-onset eating disorder.
- Trial name
- ANfMRI (NCT01882023)
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Blood Donation
Sucrosomial Iron and Iron Sulphate to Blood Donors
2 different oral iron supplementations after blood donation are compared.
- Trial name
- NCT05678647
- Testing
- Sucrosomial Iron, Iron Sulfate
- Where
- Sweden
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Uppsala University Hospital
Cardiac Arrest, Cognitive Function
Brain Function After Cardiac Arrest (Measured With FMRI and Cognitive Tests)
The aim of this longitudinal study is to determine whether brain function is affected after a cardiac arrest. The primary question is whether cognitive function is affected after cardiac arrest and whether it changes over time…
- Trial name
- BRAINnHEART (NCT03579498)
- Where
- 2 sites in Norway, Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Shame
Validation of the Swedish Translation of a Brief Shame Measure, the External and Internal Shame Scale
Shame is a normal emotion that people sometimes have. Experiencing a lot of shame has however been found to have a link to ill mental and somatic health. Therefore it is of interest to have a brief way of measuring shame.
- Trial name
- EMBER-1 (NCT07206966)
- Where
- Sweden
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Mental Health, Socio-emotional Well-being
Combining Mental Health and Parenting Interventions to Improve Child Wellbeing Among Refugee Families in Tanzania
The goal of this clinical trial is to learn whether improving caregivers' mental health and parenting practices can enhance child wellbeing among Congolese refugee families living in the Nyarugusu Refugee Camp, Tanzania.
- Conditions
- Mental Health, Socio-emotional Well-being, Functioning, Psychosocial, Parenting Behavior
- Trial name
- WEMA (NCT07447921)
- Testing
- Self Help Plus, Interaction Competencies with Children - for Parents
- Where
- 2 sites in Tanzania
- Volunteers
- 1,296 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Panic Disorder, Healthy
Neurobehavioral Correlates of Caffeine on Anxiety, Avoidance and Interoception in Healthy Individuals and Panic Disorder.
The current study is a placebo-controlled, double-blind, randomized controlled study using a cross-over design, including Healthy Controls (HC) and participants with Panic Disorder (PD).
- Trial name
- BINCAP (NCT06145490)
- Testing
- Caffeine
- Where
- 2 sites in Sweden
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Sleep, Diet Interventions
Dietary Impact on Sleep, Rhythms and Related Physiology
Sleep and metabolism are closely interconnected, and emerging evidence suggests that dietary composition may influence both sleep quality and key physiological functions such as glucose regulation, cardiovascular activity, and…
- Conditions
- Sleep, Diet Interventions, Circadian Rhythm
- Trial name
- NCT07138313
- Testing
- Low-fat dietary intervention, High-fat dietary intervention
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Brain Tumor, Childhood Cancer
Biomarkers of Brain Injury in Children With Brain Tumors
The goal of this observational study is to identify biomarkers of treatment-induced brain injury in children treated for primary brain tumors.
- Conditions
- Brain Tumor, Childhood Cancer, Childhood Brain Tumor
- Trial name
- BiomarkCBT (NCT07381959)
- Where
- Sweden
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Fibromyalgia
The Effect of Autoreactive Autoantibodies on Peripheral and Central Disease Mechanisms in Fibromyalgia.
This observational study aims to compare disease burden and pain characteristics between fibromyalgia patients with high levels of autoreactive autoantibodies, fibromyalgia patients with low levels of autoreactive autoantibodies…
- Trial name
- FINE (NCT07346950)
- Where
- Sweden
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Sepsis, Surgery
Inflammatory Mediators of Acute Kidney Injury in Intensive Care
Acute kidney injury (AKI) affects more than 50% of patients admitted to the intensive care unit. The most common underlying cause is sepsis. Severe AKI in combination with sepsis is associated with high mortality.
- Conditions
- Sepsis, Surgery, Acute Kidney Injury
- Trial name
- PronMed (NCT03720860)
- Where
- Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Material and Social Deprivation: An Enforced Lack of Necessary and Desirable Items to Lead an Adequate Life
A Randomised Controlled Trial of Healthier Wealthier Families in Sweden
Healthier Wealthier Families is a way of working, where child health nurses ask parents about their financial situation and connect them to a free financial help service, if needed.
- Trial name
- ACCESS (NCT05511961)
- Testing
- Healthier Wealthier Families
- Where
- Sweden
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Heart Failure
Uppsala Self-SCREENing of Heart Failure Study
The goal of this clinical trial is to investigate whether a stepwise multimodal home-based screening strategy with rapid point-of-care testing can detect undiagnosed heart failure (HF) in high-risk patients compared to usual…
- Trial name
- U-SCREEN-HF (NCT06940544)
- Testing
- Stepwise Multimodal Home-Based HF Screening
- Where
- Sweden
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Schizophrenia; Psychosis
Uppsala Psychosis Cohort
A multimodal longitudinal study in early stage psychosis patients and individuals at high risk for psychosis. Healthy controls are included for baseline comparisons.
- Trial name
- UPC (NCT05763966)
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Sepsis, AKI - Acute Kidney Injury
Mechanisms of Acute Kidney Injury in Severe Infections
Renal perfusion and neutrophil-mediated inflammation will be assessed in the kidney in sepsis patients with acute kidney injury using positron emission tomography.
- Conditions
- Sepsis, AKI - Acute Kidney Injury, Positron Emission Tomography (PET)
- Trial name
- PET-AKI (NCT06372444)
- Testing
- Positron emission tomography (PET)
- Where
- Sweden
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Uppsala University Hospital
Sleep Deprivation, Menstrual Cycle
The Effects of Night Shift Work on Health Across the Menstrual Cycle
The study aims to investigate the effects of sleep deprivation on women's health across different phases of the menstrual cycle.
- Conditions
- Sleep Deprivation, Menstrual Cycle, Brain Health, Metabolism
- Trial name
- MENSLEEP (NCT06683248)
- Testing
- Investigate sleep deprivation
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Fear of Spiders
The Neural Mechanisms of Imaginal Extinction
Imaginal exposure is a widely used and effective psychological treatment technique in which patients are exposed to fearful stimuli and situations using mental imagery.
- Trial name
- NCT05168592
- Testing
- Threat conditioning, Imaginal extinction
- Where
- Sweden
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Fear of Spiders
Neural Mechanisms of Imaginal and in Vivo Exposure
Imaginal exposure is a widely used and effective psychological treatment technique. Recent research suggests that neural activations and emotional responses during imaginal exposure are similar to those elicited during in vivo…
- Trial name
- NCT05193383
- Testing
- Imaginal exposure, Exposure, Approach-avoidance conflict
- Where
- Sweden
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Auditory Hallucination
SMA Targeted Magnetic Stimulation Against Auditory Verbal Hallucinations
Auditory verbal hallucinations (AVH) are prevalent among patients with psychiatric disorders. Not only being highly stressful and functionally impairing, AVH often persist despite treatment.
- Trial name
- SMA-AVH (NCT04651621)
- Testing
- continuous theta burst stimulation over the SMA
- Where
- Sweden
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Uppsala University