Clinical trials: sponsored by Uppsala University
Anxiety Disorders, Post Traumatic Stress Syndrome
Auricular Acupuncture as an add-on Treatment for Symptoms of Anxiety
Mental illness is very common in todays' society, and it is the most common cause for sick leave in Sweden. Affective diseases, such as different states of anxiety and depression, are the two most common conditions of mental…
- Trial name
- NCT04654884
- Testing
- Auricular acupuncture (AA)
- Where
- Sweden
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Oxidative Stress, Inflammation
Milk and Soured Milk (filmjölk) Intervention on Oxidative Stress and Inflammation
This study evaluates a high intake of milk compared with a high intake of soured milk (Swedish filmjölk) on markers of oxidative stress and inflammation in a randomized crossover intervention study.
- Trial name
- NCT03821116
- Testing
- Milk, Soured milk (filmjölk)
- Where
- Sweden
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Renal Failure, Anesthesia
Renal Function During Pediatric Anesthesia
It is known that volatile anesthesia, such as sevoflurane, retain water and that this appears more pronounced in children. However, the mechanisms for this effect is unknown and it is not clear if the commonly used anesthetic…
- Trial name
- NCT02571426
- Testing
- Sevoflurane, propofol
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Healthy Subjects
The Link Between Mental Imagery and the Reduction of Fear in Imaginal Extinction
Imaginal exposure is a widely used psychological treatment technique. Imaginal extinction is an experimental analogue of imaginal exposure, that allows the study of this treatment technique under controlled circumstances (Agren…
- Trial name
- NCT03989518
- Testing
- Fear acquisition, Imaginal extinction, Reinstatement
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Irritable Bowel Syndrome
Identification of IBS Metabotypes Based on Physiological Responses to Food
Irritable bowel syndrome (IBS) is a condition characterized by abdominal pain, bloating, constipation, diarrhea and gas and affects up to 15% of the Western population.
- Trial name
- NCT03653689
- Testing
- FODMAP, Gluten
- Where
- Sweden
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Individuals With Fear of Spiders
Neural Activations During Imaginal Exposure in Individuals Fearful of Spiders
This study explores the brain basis of imaginal exposure, a widely used psychological treatment technique. Specifically, this study uses functional magnetic resonance imaging to examine brain areas activated during imaginal…
- Trial name
- NCT03969160
- Testing
- Imaginal exposure
- Where
- 2 sites in Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Cholesterol, LDL
Effectiveness of Written Dietary Advice on Lipoproteins - a Pragmatic Randomized Controlled Trial
This study investigates the effect of detailed, written dietary advice for improving blood lipids, in a primary care setting. n=222 participants will be randomized to Active Intervention or Control Group.
- Trial name
- MYDICLIN (NCT03528252)
- Testing
- Written advice LDL Cholesterol, Written advice Triglycerides
- Where
- Sweden
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Dyslipidemias
Fatty Acid Biomarkers of Carbohydrate Intake
The overall aim is to investigate if circulating fatty acids and lipids are influenced by alterations in carbohydrate amount and quality.
- Trial name
- CARBIO (NCT03295448)
- Testing
- Low carbohydrate diet, High carbohydrate, high sugar diet, High carbohydrate, low sugar diet
- Where
- Sweden
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Functional Gastrointestinal Disorders
GLP-1 Inhibits Prandial Antro-duodeno-jejunal Motility in Humans
The inhibitory effect of low dose GLP-1 is investigated on prandial motility of the stomach, duodenum and jejunum in vivo in humans.
- Trial name
- GLPMOT (NCT02731664)
- Testing
- GLP-1, Intravenous saline
- Where
- Sweden
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Oro-cecal Transit Time
Rapid Orocecal Transit Time and Fermentation in IBS.
Orocecal transit time is studied in individuals with irritable bowel syndrome (IBS) of both the constipation-dominant, diarrhea-dominant, and mixed form using the lactulose hydrogen breath test for orocecal transit time through…
- Trial name
- RapidoIBS (NCT03141268)
- Testing
- Lactulose breath test
- Where
- Sweden
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Fibromyalgia
Breathing and Chest Wall Mobility in People With Fibromyalgia.
The aim of this study is to examine differences between respiratory function in female fibromyalgia patients and healthy controls. The study will also examine differences in spine mobility and pain intensity.
- Trial name
- NCT03495687
- Where
- Sweden
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Peripheral Nerve Injuries
Chronic Neuropathic Pain After Nerve Repair Hand Surgery
This study intends to compare the patients with pain with those who underwent same procedure without developing pain. The patients with pain and without pain will be further analyzed in respect to clinical differences, biomarkers…
- Trial name
- NCT03174665
- Testing
- No intervention
- Volunteers
- 990 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Sleep Deprivation, Metabolic Disturbance
Biorhythms in Metabolic Tissues
Metabolism is increasingly recognized as being highly regulated by anticipatory biological rhythms (circadian rhythms or "biorhythms"), which are driven by molecular feedback loops, and which are approximately 24 hours long…
- Conditions
- Sleep Deprivation, Metabolic Disturbance, Biological Clocks, Healthy
- Trial name
- NCT03276442
- Testing
- Low-fat dietary intervention, High-fat dietary intervention
- Where
- Sweden
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Human Papillomavirus, Cervix Cancer
Prevention of HPV in the School Health Service
The last ten years sexually transmitted infections (STI) have substantially increased among adolescents. STI can lead to individual suffering and have a negative effect on the future reproductive health and also increase the need…
- Trial name
- NCT02280967
- Testing
- Education about HPV by school nurse
- Where
- Sweden
- Volunteers
- 832 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Sexual Behavior, Lifestyle
Reproductive Life Plan-based Counseling With Men
Many women and men in fertile age are at risk for sexual transmitted infections and unwanted pregnancies, and have insufficient knowledge of health promoting lifestyle prior to conception.
- Conditions
- Sexual Behavior, Lifestyle, Fertility, Pregnancy
- Trial name
- NCT02736214
- Testing
- Reproductive Life Plan (RLP)
- Where
- 2 sites in Sweden
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Breastfeeding, Quality of Life
The Effectiveness of Proactive Telephone Support Provided to Breastfeeding Mothers of Preterm Infants
Although breast milk has numerous benefits for infants' development, with heightened effects in those born preterm (at < 37 gestational weeks), mothers of preterm infants have shorter breastfeeding duration than mothers of term…
- Conditions
- Breastfeeding, Quality of Life, Parental Stress, Attachment
- Trial name
- NCT01806480
- Testing
- Person-centred proactive breastfeeding telephone support
- Where
- 6 sites in Sweden
- Volunteers
- 493 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Obesity, Overfeeding
Overeating Different Fats and Influence on Muscle Mass and Body Fat Accumulation
To investigate metabolic and molecular response to fatty acid-specific overfeeding in overweight subjects, in relation to changes in ectopic fat, lean tissue mass and insulin sensitivity
- Conditions
- Obesity, Overfeeding, Muscle Mass, Body Composition
- Trial name
- LIPOGAIN-2 (NCT02211612)
- Testing
- PUFA-group, SFA-group
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Muscle Weakness, Vitamin D Deficiency
Vitamin D and Physical Performance Before and After Intervention and Birth Outcome in Pregnant Somali and Swedish Women
Somali migrant women, often in veiled clothing, living in a town in mid Sweden on the 60:th parallel were observed to be weak and to have a waddling gate.
- Trial name
- NCT02922803
- Testing
- 1 combination tablet of Vitamin D3/calcium per day, 2 combination tablets of Vitamin D3/calcium per day
- Where
- Sweden
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Behavioral Problems
Motivation and Adherence to Psychotherapy Assignments
The aims of this study are to experimentally investigate and compare whether motivation variables can predict adherence to a prescribed assignment in face-to-face and online interventions using a psychotherapy analogue model.
- Trial name
- AIDAII (NCT02895308)
- Testing
- Online psychoeducation, Face-to-face psychoeducation
- Where
- Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Methods to Measure Contrast Vision
A Comparative Study of Six Methods to Measure Human Contrast Vision
This study evaluates the relative performance of different methods to measure the human spectral contrast sensitivity function (CSF).
- Trial name
- NCT02767284
- Testing
- UCST-V1, UCST-V2, UCST-V3
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Uppsala University