Clinical trials: enrolling by invitation
Late Life Depression (LLD)
The Leuven Longitudinal Late-Life Depression Study
The goal of this observational study is to learn about the long-term effects of late-life depression (LLD) in adults aged 60 and older. LLD is depression that begins for the first time later in life.
- Trial name
- L4D (NCT07768098)
- Where
- Belgium
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Infertility (IVF Patients), BMI
BMI Versus Body Fat Percentage - Which is the Better Predictor of Fertility Outcomes in IVF Cycles?
The goal of this prospective observational cohort study is to evaluate whether body composition measured using bioelectrical impedance analysis (BIA) (including measures of body fat% and visceral fat) serve as a better predictor…
- Conditions
- Infertility (IVF Patients), BMI, Bioelectrical Impedance Analysis, IVF Outcomes
- Trial name
- NCT07765368
- Testing
- Measurement of BIA (Body Fat and Visceral Fat Percentage)
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Exposure, Environmental, Genetic Predisposition
Precure Targeted Accrual and Rapid Growth in Enrollment Trial Study
The goal of this observational study is to 1) better understand and predict biological processes before disease begins or is identified, 2) study genomic and environmental contributors to disease, 3) identify ways to stop disease…
- Trial name
- TARGET (NCT07756320)
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Older Adults (60 - 85 Years Old)
Gymnastics and Multicomponent Training Intervention in Community-dwelling Older Adults
Introduction: Extension projects focused on physical activity can offer health practices and promote quality of life for participants of different ages.
- Trial name
- NCT07766954
- Testing
- Multicomponent training intervention Multicomponent training intervention - Protocol includes mobility, resistance exercises for the lower and upper limbs and major muscle groups, and aerobic exercise
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Reading Disability
Executive Function in Early Childhood
Despite the fact that a substantial number of school age children struggle with both reading and math acquisition, the brain mechanisms of the overlapping aspects of reading and math skills, thought in part to be linked via…
- Trial name
- NCT03713125
- Testing
- Reading Tutoring
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Monitoring Blood Pressure, Aspirin Prophylaxis
Improving Prenatal Care to Reduce Early Onset Preeclampsia in Low-Income
The goal of this clinical trial is to learn if a telehealth hypertension group prenatal care program (Centering HER / HGPC-T) can improve blood pressure monitoring and aspirin adherence and help reduce early-onset preeclampsia in…
- Trial name
- NCT07491510
- Testing
- Active Comparator: Behavioral: Experimental: Centering HER (routine prenatal care + 7 doula-led 90-minute virtual group
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Alzheimer's Disease, Mild Cognitive Impairment
Wisconsin Brain Donor Program
The Wisconsin Brain Donor Program (WBDP) stores brain and other tissues/samples (e.g. blood and CSF) from deceased individuals who have participated in longitudinal research studies, as well as other select participants.
- Trial name
- WBDP (NCT00585572)
- Where
- United States
- Volunteers
- 9,999 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Dental Caries, Composite Resins
Clinical Evaluation of Dentin Replacement Materials in Posterior Composite Restorations
This randomized controlled clinical trial is designed to clinically evaluate and compare the performance of five dentin replacement materials used beneath posterior composite restorations.
- Conditions
- Dental Caries, Composite Resins, Composite Restoration
- Trial name
- NCT07762651
- Testing
- Biodentine, ACTIVA BioACTIVE, glass ionomer cement
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tanta University
Femoro Acetabular Impingement
Biomechanical Assessment of Femoroacetabular Impingement
The purpose of this study is to determine the influence of FAI abnormalities on hip joint biomechanics.
- Trial name
- FAI (NCT01575964)
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Utah
Gut Microbiota, Early Child Development
Gut Microbiota and Metabolic Development in Early Childhood: A 3-Year Follow-Up Study
This prospective observational birth cohort study aims to characterize the longitudinal development of the gut microbiome during early childhood and to investigate its associations with prenatal, perinatal, and postnatal…
- Trial name
- NCT07762729
- Where
- 5 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Paresis, Lumbar Disc Herniation
Validation of a Methodology Using Isometric Dynamometer for Ankle STrength Assessment to Quantify LDH-induced Paresis
Lumbar disc herniation (LDH) is a common condition that may cause lower limb motor weakness (paresis), particularly affecting ankle dorsiflexion and plantarflexion.
- Trial name
- VAST-LDH (NCT07763522)
- Testing
- Strength test validity and reliability
- Where
- Finland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Microbiome Analysis, Drug Abuse in Pregnancy
Alcohol and Cannabis Use Among Pregnant Slovenian Women
The aim of the study is to determine the prevalence of alcohol and drug use among Slovenian pregnant women. Alcohol and drug use during pregnancy has significant effects on the foetus and has short- and long-term health…
- Conditions
- Microbiome Analysis, Drug Abuse in Pregnancy, Alcohol Abuse in Pregnancy, Health Behavior, Risky
- Trial name
- NCT07456579
- Where
- Slovenia
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Physical Inactivity, Walking
Daily Goal Setting to Increase Everyday Physical Activity and Promote Cognitive Health in Midlife
The purpose of this study is to determine whether interaction with an adaptive Fitbit-based goal setting application can increase levels of everyday light intensity physical activity in middle-aged adults.
- Conditions
- Physical Inactivity, Walking, Cognitive Health, Self-regulation
- Trial name
- NCT05826379
- Testing
- Adaptive Daily Goal Setting, Interim Goal Prompt
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Gum Disease
Influence of Implant Crown Transmucosal Contour Design on Soft and Hard Tissue Clinical Outcomes
This study will evaluate how the crown's shape under the gums will influence the gum tissue around dental implants.
- Trial name
- NCT06185075
- Testing
- Implant crown delivery
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Intervention Condition, Wait-List Control
Talking Circle for Native American Youth Living Well (AYoLi)
This study, "Talking Circle for Native American Youth Living Well (A Yo Li)" uses a Community Based Participatory Research (CBPR) approach to evaluate Talking Circle effectiveness, partnering with The American Indians in Texas at…
- Trial name
- AYoLi (NCT07746375)
- Testing
- Talking Circle Intervention, Wait-List Control Group
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Melessa Kelley
Artificial Intelligence in Education, Nursing Education
The Effect of an Artificial Intelligence-Based Branching Path Simulation for First Aid Education on Nursing Students' Knowledge, Satisfaction, and Motivation
Background: Rapid advancements in educational technology are necessitating a renewal of teaching approaches in nursing education.
- Trial name
- NCT07761221
- Testing
- Artificial Intelligence-Based Branching Path Simulation for First Aid Education
- Where
- Turkey (Türkiye)
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Healthy, Covert Consciousness
Assessing Covert Consciousness During Dexmedetomidine and Ketamine Sedation: An fMRI Study
This research is studying whether mental functions take place during different levels of anesthesia, using a commonly used drug (either dexmedetomidine [with propofol in some participants] or ketamine), which shows areas in the…
- Trial name
- NCT07705022
- Testing
- Dexmedetomidine (+propofol as indicated), Ketamine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Monoclonal Gammopathy of Undetermined Significance
MGUS/MM Awareness and Genetics Insights Campaign (MAGIC) Screening Study
This study is being done to screen adults for MGUS and to better understand the genetic and immune factors linked to this condition.
- Trial name
- MAGIC (NCT06472830)
- Testing
- Non-Interventional Study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Emotion Regulation
From Toddler to Early Adolescent Emotion Regulation Strategies
This study will examine the relation between behavioral emotion regulation (ER) strategies at toddler age 3 to cognitive ER strategies in early adolescence as part of an ongoing longitudinal study of children's typical…
- Trial name
- NCT06627777
- Testing
- Laboratory tasks in early adolescence
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Miami University
Molar Incisor Hypomineralization, Fissure Sealant
Pre-etched Bioactive Versus Resin- Based Fissure Sealant for Permanent Molars Affected With Molar Incisor Hypomineralization (MIH).
This study aims to evaluate and compare the clinical performance of pre-etched bioactive fissure sealants to conventional RBFS in permanent molars affected by MIH in terms of retention, marginal integrity, caries prevention…
- Trial name
- NCT07504614
- Testing
- Pre-etched Bioactive Sealant, Conventional Resin-based Sealant
- Where
- Jordan
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
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