Clinical trials: enrolling by invitation
Alzheimer Disease, Mild Cognitive Impairment (MCI)
Alzheimer's Disease Research Center (ADRC) PET Component Study
The purpose of this study is to further engage and characterize Alzheimer's Disease Research Center (ADRC) participants through additional research opportunities, particularly PET imaging.
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment (MCI), Dementia
- Trial name
- ADRC PET (NCT07758660)
- Testing
- 18F-MK6240, 18F-Florbetaben (FBB)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Patrick Lao
Interference With Routine Analytical Tests, Stability of in Vitro Diagnostic Reagents
Interference and Stability Evaluation of the Intelligent Fingerprinting Drug Screening System
Prospective, open-label, double-dose, performance evaluation of interference effects and component stability of the Intelligent Fingerprinting Drug Screening System
- Conditions
- Interference With Routine Analytical Tests, Stability of in Vitro Diagnostic Reagents, Illicit Drug Use
- Trial name
- NCT07758907
- Testing
- Device storage condition, Interferent application
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Intelligent Bio Solutions Inc.
Perinatal Death, Hypertension, Pregnancy-Induced
Pregnancy in the Context of Urbanicity and Climate Change. The Overall Aim of the Project is to Co-create, Implement, and Test New Clinical Guidelines in Order to Improve the Quality of Care in Antenatal Clinics in the Context of Urbanisation and Climate Change in Dar es Salaam, Tanzania.
Tanzania's population is growing quickly, and Dar es Salaam is one of the fastest-growing cities in the world. At the same time, the city is increasingly affected by very hot weather, flooding, and air pollution.
- Conditions
- Perinatal Death, Hypertension, Pregnancy-Induced, Abortion, Spontaneous, Stillbirth
- Trial name
- NCT07751432
- Testing
- CC-ANC intervention group.
- Where
- Tanzania
- Volunteers
- 1,060 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Nerve; Disorder, Sympathetic, Healthy
Skin Sympathetic Nerve Activity and Sympathetic Tone
There are many sympathetic hyperactivity diseases in the investigators' clinical practice. However, the conventional method to measure the sympathetic nerve activity had many limitations such as clinical application, data…
- Trial name
- NCT03243448
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Alzheimer Disease
Neural Mechanisms of Clinically Designed Improvisatory Music for Alzheimer's Disease
Clinically Designed Improvisatory Music (CDIM) is a form of improvised music based on calm-inducing sound parameters which brought relief to our cohort of neurology patients.
- Trial name
- NCT05477862
- Testing
- Clinically Designed Improvisatory Music
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Advanced Malignant Solid Neoplasm
Group Meaning-Centered Psychotherapy for the Improvement of Wellbeing in Caregivers of Patients With Serious Illness
This clinical trial assesses the acceptability and feasibility of a virtual group Meaning-Centered Psychotherapy for Cancer Caregivers (MCP-C) and its effect in improving the wellbeing of caregivers of patients with advanced…
- Trial name
- NCT06630351
- Testing
- Behavioral Counseling, Discussion, Health Promotion and Education
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Postoperative Pain After Spinal Surgery
Compined Lumber Longissimus Plane Block and Multifidus Longissimus Plane Block Versus Infiltration Field Block in Lumber Spine Surgery
Lumbar spine surgery is one of the most commonly performed procedures for degenerative spinal disorders, including lumbar disc herniation, spinal stenosis, and degenerative disc disease.
- Trial name
- LLP/MLP (NCT07681648)
- Testing
- Ultrasound-Guided Bilateral Combined LLP and MLP Block, [Ultrasound-Guided Bilateral Combined LLP and MLP Block], [Conventional Wound Infiltration with Bupivacaine]
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Engy Emil
Depression
Intern Health Study
Retrospective studies have established a strong correlation between reports of life stress and depression. Investigators have begun to further explore this relationship by examining the role of gene x stress interactions in the…
- Trial name
- NCT01809080
- Where
- United States
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- University of Michigan
IPMN, Pancreatic, Pancreas Cancer
The LINFU® U.S. Registry in Patients With IPMN (Intraductal Papillary Mucinous Neoplasm of the Pancreas)
In this study, LINFU® will be evaluated in patients who have been identified with IPMN to determine if it can be used to help identify early, pancreatic ductal adenocarcinoma and its noninvasive precursor lesions (dysplasia).
- Conditions
- IPMN, Pancreatic, Pancreas Cancer, Pancreatic Cyst
- Trial name
- NCT06276764
- Testing
- LINFU®
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Adenocyte, LLC
Suicide Prevention, Suicide Risk | Patient
Pilot Testing Suicide Risk Prediction Algorithms in Primary Care
The goal of this pilot study is to learn whether the use of suicide risk prediction algorithms in primary care can help identify people who may benefit from extra mental health monitoring.
- Trial name
- NCT07068685
- Testing
- Suicide risk prediction algorithm
- Where
- United States
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Pollution; Exposure, Neurodevelopmental Disorders
Air Pollution and Development in the Boricua Youth Study
This study seeks to understand the relationship between prenatal maternal air pollution exposure and offspring risk for ADHD and examine two potential -modifiable- mechanisms: prenatal maternal inflammation and offspring sleep…
- Trial name
- NCT05368493
- Testing
- MRI task
- Where
- 2 sites in United States, Puerto Rico
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Emotion Regulation Difficulties, Risky Behaviors
Emotion Regulation for Middle Schoolers
Early adolescence (ages 11-14) is a key developmental period repeatedly coupled with the onset of mental health problems. Middle schools provide a naturalistic setting in which to implement programming to prevent the development…
- Trial name
- iTRAC+ (NCT07749885)
- Testing
- iTRAC+, iTRAC
- Where
- 2 sites in United States
- Volunteers
- 990 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Procedure-Related Pain, Procedure-Related Fear
Magic Show Featuring "Kuco" for Pain and Fear During Invasive Procedures
Children frequently experience pain and fear during invasive procedures such as venipuncture and peripheral intravenous catheter insertion.
- Conditions
- Procedure-Related Pain, Procedure-Related Fear, Peripheral Intravenous Catheterization, Venipuncture
- Trial name
- Kuco-Magic (NCT07746973)
- Testing
- Kuco Magic Show
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Inonu University
HEPATITIS C (HCV)
North Jersey Community Research Initiative (NJCRI) Study on Transgender Liver Health
Primary Objective: Assess disparities in liver health outcomes among transgender individuals on GAHT by evaluating liver function markers (transaminases, bilirubin levels, etc), as well as liver elasticity and presence of liver…
- Trial name
- NCT07746999
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Corey DeStefano
Chronic Musculoskeletal Pain
Network Modeling in Knee Osteoarthritis
This project seeks to understand inter-individual differences in chronic musculoskeletal pain (cMSKP). Our long-term objective is to develop clinically-feasible decision tools that enable whole-person assessment and management of…
- Trial name
- NCT07746284
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- George Mason University
Fetal Growth, Obstetric Ultrasonography
Clinicians' Trust in AI-Based Fetal Growth Estimates
This study examines how clinicians trust and use artificial intelligence (AI) when estimating fetal weight during pregnancy. Accurate assessment of fetal growth is important for identifying growth problems that may affect…
- Conditions
- Fetal Growth, Obstetric Ultrasonography, Pregnancy, Clinical Decision-making
- Trial name
- NCT07401368
- Testing
- Intervention - AI Performance Information
- Where
- Denmark
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
NSAID (Non-Steroidal Anti-Inflammatory Drug), Lumbar Spine Fusion
NSAIDS Following Elective Lumbar Spine Fusion
This study will compare two common approaches to pain control after lumbar spinal fusion surgery. Participants will be randomly assigned to receive either standard pain medication alone or standard pain medication plus a short…
- Conditions
- NSAID (Non-Steroidal Anti-Inflammatory Drug), Lumbar Spine Fusion, Ketorolac, Postoperative Pain
- Trial name
- NCT07743606
- Testing
- Ketorolac, Naproxen, Standard Postoperative Pain Management
- Where
- United States
- Volunteers
- 428 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Circadian Rhythms
Real-World Use of an iPad-Based Light Therapy App, With Optional Biomarker Collection
This study looks at how adults use an iPad-based light app in everyday life. Light is the main signal that sets the body's internal clock, which controls daily rhythms in sleep, alertness, and many other body systems.
- Trial name
- NCT07744711
- Testing
- Circadian OS iPad-based light app
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Circadian OS, Inc
Cervical Cancer Screening
Mail-in HPV Screening Program in NJ
The purpose of this study is to help people who have missed their regular cervical cancer screening. The investigators are evaluating whether mailing an HPV self-sampling kit to participant home makes it easier and more…
- Trial name
- NCT07575217
- Testing
- BD Onclarity HPV test, Standard Pap Smear
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Sleep, Neurology
Establishment of a Sleep and Sleep-disorder Research Cohort in Patients With Neurological Disorders
This study aims to establish a research cohort on sleep and sleep disorders in patients with neurological diseases to systematically evaluate the relationship between various neurological conditions and sleep characteristics or…
- Trial name
- NCT07374393
- Testing
- Symptomatic and Etiological Treatment
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Jilin University
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