Clinical trials: active, not recruiting
Obesity, Weight Loss
A Multidisciplinary Weight Loss Program at AUB-MC
The current project aims at evaluating the feasibility and efficacy of a multi-disciplinary weight loss program, using an innovative and simple dietary intervention at the American University of Beirut Medical Center (AUB-MC).
- Trial name
- NCT04194424
- Testing
- Multidisciplinary weight loss program, Standard Care, Metformin Hcl 850Mg Tab
- Where
- Lebanon
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Healthy Volunteers, Overweight or Obesity
A Study of Multiple Doses of Orally Administered RO7795081 in Otherwise Healthy Chinese Adult Participants With Obesity or Overweight
This is an investigator- and participant-blind, randomized, placebo-controlled, parallel-group, Phase I study evaluating the safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple doses of orally administered…
- Trial name
- NCT07499050
- Testing
- RO7795081
- Where
- 2 sites in China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
HPV Infection
An Exploratory Open-Label Clinical Trial Evaluating the Immunogenicity of the 9-valent 2-dose HPV Vaccination Regimen
The goal of this study is to explore and evaluate whether a 2-dose schedule of Gardasil 9 among young and mid-adult women 16-45 years of age is generally safe and immunogenic, with an antibody response that is not inferior to…
- Trial name
- NCT04206813
- Testing
- Gardasil 9 2 dose regimen, Gardasil 9 3 dose regimen, Gardasil 9 rescue dose
- Where
- United States
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Arterial Stiffness, White Matter Lesions
Effect of Equol Supplementation on Arterial Stiffness and Cognition in Healthy Volunteers
The ACE Trial, funded by the National Institute on Ageing/National Institutes of Health (NIH), is a multicenter clinical trial. The ACE Trial will determine if taking the dietary supplement Equol could slow the progression of…
- Conditions
- Arterial Stiffness, White Matter Lesions, Cognitive Decline
- Trial name
- ACE (NCT05741060)
- Testing
- S-equol
- Where
- 3 sites in United States
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- Akira Sekikawa
Electric Stimulation Therapy, Obesity
Effects of Brain Stimulation on Food Intake and Behavioral Weight Loss Treatment
This study will determine whether electrical stimulation of an area of the brain called the dorsolateral prefrontal cortex, which is important in determining the feeling of fullness after eating, affects how much food a person…
- Conditions
- Electric Stimulation Therapy, Obesity, Weight Loss, Eating
- Trial name
- NCT00739362
- Testing
- Transcranial Direct Current Stimulation (TDCS)
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Overweight, Obesity
A Study to Learn How the Study Medicine Called PF-08653945 is Taken up Into the Blood in Adults With Overweight or Obesity
This study is being done to learn how the study medicine affects the body. It will also assess how safe it is for people who take it. The researchers will use blood tests to measure how much medicine is in the blood.
- Conditions
- Overweight, Obesity, Healthy
- Trial name
- NCT07725809
- Testing
- PF-08653945
- Where
- Belgium
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Pfizer
Yellow Fever Immunization
A Phase III Control Study of the Safety and Immunogenicity of vYF in Pediatric Population
The purpose of this study is to determine whether vYF (investigational vaccine) is safe and can help the body to develop antibodies (immunogenicity) compared with Stamaril vaccine and YF-VAX vaccine (both licensed vaccines) and…
- Trial name
- NCT07103148
- Testing
- Yellow fever vaccine (live), Measles, combinations with mumps and rubella, live attenuated
- Where
- 15 sites in Honduras, Mexico and 1 more
- Volunteers
- 2,440 people, healthy volunteers welcome
- Sponsor
- Sanofi
Herpes Zoster (HZ), Infectious Diseases
A Phase 2 Study to Evaluate JCXH-105, an srRNA-based Herpes Zoster Vaccine
The goal of this clinical trial is to assess the safety and immunogenicity of an srRNA-based vaccine, JCXH-105, in the prevention of Herpes Zoster (Shingles). Subjects will be randomized to receive either JCXH-105 or Shingrix.
- Conditions
- Herpes Zoster (HZ), Infectious Diseases, Shingles
- Trial name
- NCT06581575
- Testing
- JCXH-105, Shingrix
- Where
- 8 sites in United States
- Volunteers
- 467 people, healthy volunteers welcome
- Sponsor
- Immorna Biotherapeutics, Inc.
Healthy Participants
A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Enicepatide in Generally Healthy Adult Chinese Participants
This is a Phase I, randomized, double-blinded, placebo-controlled, study to assess the safety, tolerability, and pharmacokinetics (PK) of enicepatide in generally healthy adult Chinese participants with body mass index (BMI)…
- Trial name
- NCT07626515
- Testing
- Enicepatide
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Respiratory Syncytial Virus (RSV), Infectious Disease
A Phase 1 Study to Evaluate JCXH-108, an mRNA-based Vaccine Against RSV
The goal of this clinical trial is to assess the safety, reactogenicity and immunogenicity of an mRNA-based vaccine, JCXH-108, the prevention of Respiratory Syncytial Virus (RSV) infection and diseases.
- Trial name
- NCT06564194
- Testing
- JCXH-108
- Where
- 3 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Immorna Biotherapeutics, Inc.
Ketogenic Diet, Control Condition
Effects of Short-term Adaptation to Ketogenic Diet on Endurance Trained Athletes
Skeletal muscle glycogen is a major endogenous carbohydrate store and an important substrate for ATP resynthesis during exercise.
- Trial name
- NCT07838818
- Testing
- Ketogenic diet, Control Diet
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Padova
Pseudofolliculitis Barbae
Shaving Satisfaction in Males With Skin Irritation From Shaving
The purpose of this research study is to evaluate the improvement in overall shave satisfaction, the appearance of skin irritation from shaving, and the razor related inflammation of the hair follicles when using a new razor…
- Trial name
- NCT03569956
- Testing
- 556 Razor
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Periodontal Disease, Periodontitis
Antibiotic Resistance Genes in Periodontitis
Antimicrobial resistance (AMR) is a major global public health concern, and the oral microbiome may serve as an important reservoir of antibiotic resistance genes (ARGs).
- Conditions
- Periodontal Disease, Periodontitis, Antibiotic Resistance Genes
- Trial name
- NCT07887204
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Stress (Psychology), Anxiety
HRVB for Stress and Anxiety During Dentistry Students' Clinical Transition
The goal of this clinical trial is to learn if Heart Rate Variability Biofeedback (HRVB) can reduce stress and anxiety in dentistry students during the transition from pre-clinical training to clinical practice.
- Conditions
- Stress (Psychology), Anxiety, Psychological Distress
- Trial name
- HRVB-MIMD (NCT07415915)
- Testing
- Heart Rate Variability Biofeedback (HRVB) Training
- Where
- Portugal
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Generalized Anxiety Disorder, Oxygenation Sensitive CMR
BreathinG-induced Myocardial and Cerebral Perfusion in Anxiety Disorders
This study aims to view variations in MRI measurements of the heart and the brain in people with anxiety versus healthy volunteers.
- Trial name
- B-GLAD (NCT05574140)
- Testing
- Cardiac MRI
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Diabetes Mellitus, Obesity-Related Malignant Neoplasm
Eat, Move, Live Program for the Reduction of Cancer and Chronic Disease Risk in Underserved Communities
This clinical trial tests the Eat, Move, Live (EML) Program in reducing the risk of chronic diseases among underserved communities by improving healthy lifestyle practices, increasing physical activity and encouraging healthy…
- Trial name
- NCT05414396
- Testing
- Behavioral Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 347 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Friedreich Ataxia
Characterisation of the Cognitive Profile of Patients Suffering From Friedreich's Ataxia
Friedreich's Ataxia (FA) Friedreich's Ataxia is a neurodegenerative disease caused by a homozygous expansion of the GAA triplet repeats of the frataxin gene (FXN). FA usually begins in childhood or adolescence.
- Trial name
- CPCAF (NCT05874388)
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Rheumatoid Arthritis, Rheumatoid Arthritis (RA)
Overactive Bladder Symptoms and Urinary Incontinence In Women With Rheumatoid Arthritis
The primary aim of this study is to compare the frequency and severity of overactive bladder (OAB) symptoms and urinary incontinence (UI) in women diagnosed with Rheumatoid Arthritis (RA) with a control group of healthy women.
- Conditions
- Rheumatoid Arthritis, Rheumatoid Arthritis (RA), Urinary Incontinence (UI)
- Trial name
- NCT07916623
- Where
- Turkey (Türkiye)
- Volunteers
- 393 people, healthy volunteers welcome
- Sponsor
- Ege University
Breast Cancer Survivors
A Study of Attention and Memory Processes in Breast Cancer Survivors
The purpose of this study is to observe the attention and memory processes in breast cancer survivors. Both cancer survivors and healthy volunteers (who are the same age as the cancer survivors) will participate in this study so…
- Trial name
- NCT04883398
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Major Depressive Disorder
Neural Circuit Effects of Ketamine in Depression
This project is designed to examine the role of the subgenual anterior cingulate cortex (sgACC) in anhedonia and anxiety in humans with depression, as well as the acute and sustained effects of ketamine on agACC activation and…
- Trial name
- NCT06213324
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
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