Clinical trials: enrolling by invitation
Hypoplastic Left Heart Syndrome
Fetal Aortic Valvuloplasty for Evolving Hypoplastic Left Heart Syndrome
The purpose of this research is to investigate the best way to manage evolving hypoplastic left heart syndrome (HLHS).
- Trial name
- NCT06342999
- Testing
- Fetal Aortic Valvuloplasty Procedure, Emerge Monorail and Over-The-Wire PTCA Dilatation Catheter, Trek RX and Mini Trek RX Coronary Dilatation Catheter
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mauro H. Schenone
Work-Related Condition, Burnout, Caregiver
Effectiveness of the Healthy Workplace Participatory Program With Peer-led Teams in Public Sector Healthcare Facilities
Safety \& Health through Integrated, Facilitated Teams (SHIFT) is an intervention study to enhance employee health, safety, and well-being in public sector healthcare institutions in New England.
- Conditions
- Work-Related Condition, Burnout, Caregiver, Work-related Injury, Musculoskeletal Pain
- Trial name
- SHIFT (NCT04251429)
- Testing
- CPH-NEW Healthy Workplace Participatory Program
- Volunteers
- 3,300 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Lowell
Physical Activity, Physical Activity Intensity
Effects of Polarized and Threshold Intensity Distribution Models on Race Time and Body Composition in Recreational Runners Aged 20-45 Years.
This study aims to compare the effects of two intensity distribution training (TID) models-polarized and threshold-on 5-km race time and body composition in recreational runners aged 20 to 45 years.
- Conditions
- Physical Activity, Physical Activity Intensity, Physical Activity in Adults, Running
- Trial name
- NCT07498608
- Testing
- Polarized intensity distribution model, Threshold intensity distribution model
- Where
- Colombia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Pedagogica Nacional, Colombia
Pregnancy Related, Infant Development
Mother Infant Nutrition Study
Early life influences (including the intrauterine environment, birth weight, and early postnatal growth) shape subsequent weight trajectories and future chronic disease risk.
- Trial name
- MINT (NCT04132310)
- Testing
- N/A This is an observational study.
- Where
- 2 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Solid Tumors
A Study Using White Blood Cells From Healthy Donors To Treat Solid Cancers
Background \& Rationale: About 75% of US population living today will not die of cancer. There has been a recent report of a colony of cancer-resistant mice developed from a single male mouse that unexpectedly survived challenges…
- Trial name
- NCT00900497
- Testing
- White Blood Cells/Granulocytes
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Dipnarine Maharaj
Depression, Anxiety
Preliminary Testing and Development of a Short Digital Intervention for Patients on Waiting Lists for Psychological Treatment
The goal of this randomized pilot feasibility trial is to assess the feasibility and further develop a single-session digital mental health intervention for patients on waiting lists for psychological treatment.
- Trial name
- NCT07499219
- Testing
- Digital therapy program (short), Digital therapy program (long), Mental health advice
- Where
- Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Low Back Pain and Core Muscle, Disc Herniation
Neural Control and Mechanosensation in Spine Muscle
Low back pain (LBP) is a condition that affects a majority of the US population and is responsible for a significant proportion of health care costs and utilization.
- Trial name
- NCT07003802
- Testing
- Resistance exercise
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Frailty
Safety, Efficacy of FFP From Healthy Donors to Ameliorate Frailty and Enhance Immune Function in Older Individuals
1. Primary Objective To determine the safety and tolerability of 12 once monthly transfusions of GMFFP (Granulocyte - Colony Stimulating Factor (G-CSF) Mobilized Fresh Frozen Plasma harvested from young, healthy donors), given to…
- Trial name
- NCT03458429
- Testing
- GMFFP
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dipnarine Maharaj
Insulin Resistance
Carbohydrate Loading in Lowering Perioperative Insulin Resistance in Pediatric Surgery
It is a double blinded randomized controlled trial interventional study, examining the effect of carb loading given prior to surgery on preventing post operative insulin resistance in pediatric patients undergoing elective surgery
- Trial name
- NCT07545538
- Testing
- Carbohydrate loading
- Where
- Indonesia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gadjah Mada University
HIV Prevention, HIV Pre-exposure Prophylaxis
Client-Centered Care Coordination for Black Men Who Have Sex With Men
The goal of this clinical trial is to determine the efficacy of a client-center care coordination intervention (C4) in improving pre-exposure prophylaxis (PrEP) adherence in Black men who have sex with men (MSM).
- Trial name
- NCT06056544
- Testing
- Client Centered Care Coordination
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Art Therapy
The Effects of an Intermodal Art Therapy Program on Depression, Anxiety, Stress, and Emotion Regulation Skill Levels in Nursing Students: A Randomized Controlled Study
Nursing students face stress during their education, especially when transitioning to clinical practice; poorly managed stress reduces academic achievement and increases levels of depression and anxiety.
- Trial name
- NCT07560241
- Testing
- Art Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Atlas University
Vision Disorders, Diabetes
Implementing Artificial Intelligence to Prevent Vision Loss From Diabetes
This pragmatic clinical trial is being conducted to test the effectiveness of AI in improving screening and follow-up eye care compared to usual-care among patients with diabetes across 4 primary care clinics.
- Trial name
- NCT07559292
- Testing
- AI, Usual Practice
- Where
- United States
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Occupational Health, Sleep
Using Cognitive-Behavioral Change and Mobile Technology to Improve RN Sleep and Fatigue
The U.S. registered nurse (RN) workforce is the largest in the Healthcare and Social Assistance Sector and is at high risk for injuries and errors due to poor sleep and fatigue.
- Conditions
- Occupational Health, Sleep, Fatigue, Nurse
- Trial name
- RN-SLEEP (NCT06105307)
- Testing
- RN-SLEEP, Healthy Habit - Educational Control
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Radiology, Internship and Residency
Measuring AI Reliance Among Intern Doctors in Palestine
This study aims to enroll intern doctors and have them sit one of three identical radiology exams. The only difference between them is an AI-assistant.
- Conditions
- Radiology, Internship and Residency, AI (Artificial Intelligence)
- Trial name
- AI-RP (NCT07558746)
- Testing
- AI prompt (Correct), AI prompt (Incorrect)
- Where
- Palestinian Territories
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Al-Quds University
Mindfulness Training
Effect of a Mindfulness Training Program on Surgical Nurses
This randomized controlled single-blind study aims to evaluate the effect of mindfulness training on mindfulness levels, psychological resilience, and work motivation among surgical nurses.
- Trial name
- NCT07553169
- Testing
- Mindfulness Training
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- SELDA MERT
Scopolamine or Placebo, Schema to Organize Memory or no Schema
Representation of Spatiotemporal Information in Human Episodic Memory and Navigation
Neural diseases such as stroke can have distinct effects on the ability to navigate and orient compared to remembering daily events like when one last took medicine.
- Trial name
- NCT07423923
- Testing
- Scopolamine
- Where
- 2 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Arsenic and/or Arsenic Compound Adverse Reaction
Mitigation Efforts in Arsenic Exposure With Folic Acid Supplementation
The purpose of this study is to evaluate the effects on folic acid supplementation in a population living in an environment with chronic arsenic exposure in Birmingham, Alabama.
- Trial name
- NCT05656664
- Testing
- Folic Acid
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Bruxism
Neuromuscular Function and Performance in Athletes With or Without Bruxism
The aim of this study is to evaluate the associations between bruxism and neuromuscular function, as well as athletic performance, in a population of amateur athletes.
- Trial name
- CHAINSPORT (NCT07556211)
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mainjot Amélie
Education, Medical, Ultrasound Imaging
Artificial Intelligence for Learning Point-of-Care Ultrasound
Point-of care-ultrasonography has the potential to transform healthcare delivery through its diagnostic and therapeutic utility.
- Trial name
- NCT05900440
- Testing
- Ultrasound with Artificial Inteligence Engabled, Ultrasound without Artificial Intelligence Enabled
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Stanford University
To Compare the Time Required to Administer 1 mg of Epinephrine, as Well as the Total Procedure
Vascular Access and Intraosseus
Rapid administration of epinephrine is an essential component of advanced life support during cardiac arrest. Peripheral intravenous (IV) access is commonly used for drug delivery, while intraosseous (IO) access is an alternative…
- Trial name
- IO_nursing (NCT07471555)
- Testing
- Epinephrine Ampoule (Manual Preparation), Epinephrine Prefilled Syringe (Ready-to-use), Intravenous (IV) Access
- Where
- Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Valencia
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