Clinical trials: enrolling by invitation
Proportional Reasoning
Modifying Cognitive Strategies for Comparing Proportions
The goal of this study is to understand the cognitive processes underlying quantitative and relational reasoning, including the understanding of mathematical information (e.g., numbers, proportions, percentages, geometry) and…
- Trial name
- NCT06635577
- Testing
- Verbal Interference Task
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Michelle Hurst, PhD
Alzheimer Disease
Alzheimer's Registry
The design is an open-ended, prospective, observational, (non-interventional) registry for subjects with mild cognitive impairment (MCI), early symptomatic Alzheimer's disease, Alzheimer's disease, or dementia with clinical…
- Trial name
- ALZ (NCT07420075)
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- CorEvitas
Overweight, Children
010Fit'R - Healthy Lifestyle Interventions for Children With Overweight
Overweight is a leading risk factor for non-communicable diseases. In the Netherlands, about 11% of children aged 4-12 years are overweight.
- Trial name
- 010Fit'R (NCT07419503)
- Testing
- 010 Fit'R intervention
- Where
- Netherlands
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Intrahepatic Cholestasis of Pregnancy, Respiratory Distress Syndrome, Newborn
Impact of Intrahepatic Cholestasis of Pregnancy on Neonatal Respiratory Outcomes
Intrahepatic cholestasis of pregnancy is a liver condition in late pregnancy, causing itching and high bile acid levels that return to normal after birth.
- Trial name
- CHOLE-RESP (NCT06679972)
- Where
- Romania
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Carol Davila University of Medicine and Pharmacy
Healthy
Neurofeedback Training of Anterior Insula Activity Based on Unidimensional vs. Multidimensional Interoceptive Regulation Strategies
The purpose of this study is to compare the neural and behavioral effects of real-time functional magnetic resonance imaging (fMRI) neurofeedback training using two different interoceptive strategies: a unidimensional heartbeat…
- Trial name
- NCT07416370
- Testing
- real-time fMRI neurofeedback training
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Achalasia
Per-Oral Endoscopic Myotomy (POEM) for the Treatment of Achalasia, Database Repository
POEM (Per-Oral endoscopic myotomy (creating a muscle [esophagus] opening), an incision-less (no cutting of the surface of the body) endoscopic procedure, is an effective non-surgical alternative to release the muscle \& sphincter…
- Trial name
- POEM (NCT02770859)
- Testing
- POEM (Per Oral Endoscopic Myotomy)
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Indiana University
Migraine, Cluster Headache
Pain Biomarker Study
This study investigates molecular and physical biomarkers of headaches in order to better understand mechanisms of these diseases. There are 3 main parts: 1.
- Conditions
- Migraine, Cluster Headache, Trigeminal Autonomic Cephalgia, Hemicrania Continua
- Trial name
- PBS (NCT03511846)
- Testing
- Oral capsaicin, Topical capsaicin, Intranasal capsaicin
- Where
- United States
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Healthy 70 Street Market Vendors Working in Highly-polluted Areas of Turin
Biotics Intervention Oriented to Rescue From Environmental Pollution Inflammatory Responses
Improving air quality in urban areas represents a major public health challenge. In regions such as the Po Valley, airborne particulate matter (PM₁₀ and PM₂.₅) concentrations frequently exceed World Health Organization limits…
- Trial name
- BIOREPAIR (NCT07418489)
- Testing
- pro-postbiotic
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Inflammatory Bowel Diseases
Mayo Clinic IBD Biobank
Researchers are collecting and storing blood, stool, and urine samples and medical information to better understand Inflammatory Bowel Disease (IBD) to improve disease outcome.
- Trial name
- NCT03756649
- Testing
- Blood Draw, Urine Collection, Stool Collection
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
HIV
Spironolactone and XPB-1 Integrity in the TFIIH Complex
This is a prospective, interventional, exploratory clinical study designed to evaluate the pharmacokinetics, safety, and biological effects of spironolactone on the degradation of the XPB (ERCC3) protein and its potential impact…
- Trial name
- SPIRIT-XPB (NCT07415811)
- Testing
- Spironolactone (drug)
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Peri-Implantitis, Surgery
Surgical Treatment of Peri-implantitis Using a Bone Substitute With or Without a Resorbable Collagen Membrane
The objective of the present randomized clinical trial will be to compare two surgical methods of treating peri-implantitis. This study will determine if surgical debridement of peri-implantitis bone defects, including air powder…
- Trial name
- NCT05699343
- Testing
- InterOss Collagen (Bone xenograft) and InterOss Collagen Guide (Collagen membrane), InterOss Collagen (Bone xenograft)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Andrea Ravida
Ankle Injuries
Neurophysiology of Ankle Instability
Chronic ankle instability (CAI) is a common debilitating orthopedic condition that disrupts physical function and decreases quality of life. Not all CAI is the same.
- Trial name
- NCT06576687
- Testing
- Physical Rehabilitation
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Dietary Protein Intake
App-based Protein Support for Older Adults; Coaching Towards Healthy Ageing
Rationale: Sufficient dietary protein intake helps to preserve muscle mass and strength and is a key factor in healthy ageing. Achieving an increased protein intake with regular food products has shown to be a challenge for many…
- Trial name
- APPROACH (NCT07415408)
- Testing
- Nutritional coaching via an app, Exercise recommendations
- Where
- Netherlands
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Contraception Behavior, Sexual Behavior
Evaluating the Impact of CHOICE-AYA on Contraceptive Use, Continuation and Satisfaction
This is a prospective study involving two phases: 1) adaptation and 2) intervention, in adolescents aged 14-21 experiencing homelessness.
- Conditions
- Contraception Behavior, Sexual Behavior, Reproductive Behavior
- Trial name
- CHOICE-AYA (NCT05022134)
- Testing
- CHOICE-AYA
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Health Personnel, Stress
Cereset Research for Performance Improvement in a Hospital Nursing Unit
The purpose of this study is to explore whether an implementation process composed of offering CR to staff in a single hospital nursing unit has any potential impact on unit-level quality measures post-implementation.
- Conditions
- Health Personnel, Stress, Anxiety, Insomnia
- Trial name
- NCT06378554
- Testing
- Cereset Research
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Healthy Adult, Whole Body Vibration
FREQUENCY-DEPENDENT SOLEUS REFLEX MODULATION DURING WHOLE-BODY VIBRATION
Exposure to microgravity leads to pronounced impairments in neuromuscular control, postural stability, and spinal reflex regulation that cannot be attributed to muscle atrophy alone.
- Trial name
- NCT07408570
- Testing
- whole body vibration
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Body, Knees
Micro-Coring® for the Treatment of Skin Laxity of the Knees
Early, informal clinical experience suggests that Micro-Coring may help improve skin quality in certain body areas, such as the knees. However, this body region has not yet been formally studied.
- Trial name
- NCT07409090
- Testing
- Micro-Coring
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cytrellis Biosystems, Inc.
Complex Regional Pain Syndrome, Pain
CSS-SR Validation Study
Complex Regional Pain Syndrome (CRPS) is an orphan condition with no interventions proven effective in large-scale clinical trials.
- Trial name
- NCT06798493
- Testing
- Complex Regional Pain Syndrome (CRPS) Severity Score - Self Report
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Medication Review, Primary Care
A Swiss Interprofessional Network for Reviewing Inappropriate Medication in Primary Care
The aim of the SINERGIC pilot study is to assess the feasibility in the Swiss context of implementing interprofessional medication reviews between GP and pharmacists, as part of a shared decision-making process with patients.
- Trial name
- SINERGIC (NCT07283055)
- Testing
- Medication review
- Where
- Switzerland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Bern
Breast Carcinoma
MammoScreen Breast Cancer Risk Assessment and Decision Aid for Breast Cancer Screening and Referrals
This study collects information to implement MammoScreen for Breast Cancer Screening and Referrals. MammoScreen is a risk assessment questionnaire that identifies individuals at average and increased risk for breast cancer and…
- Trial name
- NCT04996316
- Testing
- Electronic Health Record Review, Interview, Media Intervention
- Where
- United States
- Volunteers
- 1,141 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.