Clinical trials: enrolling by invitation
Smoking Cessation, Hiv
Botswana Smoking and Abstinence Reinforcement Trial
Many people living with HIV in southern Africa, specifically Botswana use tobacco products. Using tobacco makes some of the effects of HIV worse and even causes excess deaths.
- Trial name
- BSMART (NCT05694637)
- Testing
- Screening, Brief Intervention and Referral to Treatment (SBIRT) intervention consisting of the 5As, (Ask, Advise, Assess, Assist, Arrange), Varenicline
- Where
- 15 sites in Botswana
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Multiple Sclerosis, Healthy
Immune Profiles in Multiple Sclerosis (MS) Patients and Healthy Volunteers Through Thoracic Duct Cannulation
In this study, lymph fluid will be collected by cannulation of the thoracic duct, a minimally invasive procedure performed by interventional radiologists.
- Trial name
- NCT05162638
- Testing
- thoracic duct cannulation
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Artificial Intelligence, Biomedical Research
Attitudes and Perceptions of Corresponding Authors From Top International Medical Journals Regarding the Use of Artificial Intelligence in the Scientific Process
"Artificial intelligence (AI), including large language models and conversational tools, is increasingly being used in medical research.
- Conditions
- Artificial Intelligence, Biomedical Research, Scientific Publishing, Surveys and Questionnaires
- Trial name
- AISurvey6 A+ (NCT07326501)
- Testing
- observational survey
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Young Football Players, Ankle Sprain Prevention
Comparison Interventions on Kinetic and Kinematic Parameters
Currently, it is difficult to find studies in the literature comparing proprioception exercises with the effect of manual therapy on improving balance, and in the long run it may translate into improved activity, functionality…
- Trial name
- Balance (NCT07326475)
- Testing
- Manual therapy, Exercise
- Where
- Poland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Overuse Injury, Traumatic Injury
Sustainable Elite Football
The literature is scarce when it comes to more comprehensive research project that investigates the differences between youth and adult elite football players in physical parameters and the risk of injury.
- Trial name
- NCT07325084
- Where
- Sweden
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Linnaeus University
Nutritional and Metabolic Diseases
Saskatoon Berry on Metabolism and Gut Microbiota in Healthy Subjects
Diabetes becomes epidemic in worldwide countries. Nine out of ten diabetic patients are type 2 diabetes (T2D). T2D is characterized by insulin resistance and obesity.
- Trial name
- NCT04809688
- Testing
- Saskatoon berry, Dried Saskatoon berry
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Pregnancy - Prenatal Testing
GRAPE-GDM Prospective Comperative Trial - Grape Juice as a Replacement Drink for Gestational Diabetes Screening
Study Type: Observational, prospective, multicenter comparative study Primary Purpose: The goal of this study is to evaluate whether grape juice can serve as an effective alternative to the standard 50g glucola drink for…
- Trial name
- GRAPE-GDM (NCT07323901)
- Testing
- Participants will consume 500 ml of commercially available grape juice which contains 50g of sugar, serving as an alternative glucose load.
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Mitochondrial Disorders, Mitochondrial Disease
Tissue Sample Study for Mitochondrial Disorders
The investigators are studying patients with undefined mitochondrial diseases to identify genetic mutations in nuclear or mitochondrial Deoxyribonucleic Acid (DNA).
- Conditions
- Mitochondrial Disorders, Mitochondrial Disease, Melas, Kearns Sayer
- Trial name
- NCT01803906
- Where
- United States
- Volunteers
- 6,900 people, healthy volunteers welcome
- Sponsor
- Columbia University
Volunteer Subjects
Clinical PRoduct DevelOpment StudyinG the QT Ultrasound® BReast ScannEr With Volunteer SubjectS
Subjects will be scanned on the QT Ultrasound Breast Scanner. For subjects that may have breast calcifications and/or mass(es) and/or other finding(s) on the QT scan image(s), standard imaging modalities (e.g., mammogram and…
- Trial name
- PROGRESS (NCT02948361)
- Testing
- QT Ultrasound Breast Scan
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- QT Ultrasound LLC
Fibromyalgia
Adversity as a Factor Associated With the Development of Fibromyalgia in Patients With Rheumatologic Diseases and Healthy Controls
Adverse experiences, such as exposure to stressful or traumatic events, have been consistently associated with immune system dysfunction, accelerated inflammatory processes, and an increased risk of developing musculoskeletal…
- Trial name
- NCT07301944
- Where
- Mexico
- Volunteers
- 534 people, healthy volunteers welcome
- Sponsor
- National Institute of Medical Sciences and Nutrition, Salvador Zubiran
Pregnancy, Gestational Age and Weight Conditions
Effectiveness of a Mobile Health Program in Pregnant Women
1. To evaluate the usability and user experience of the i-PregMom mobile application and digital dietary image recording among pregnant women. 2.
- Conditions
- Pregnancy, Gestational Age and Weight Conditions, Eating Behaviors, Literacy
- Trial name
- NCT06917703
- Testing
- E-learning
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Procedural Pain, Fear Anxiety
The Effect of Two Different Interventions on Emotional State, Pain, and Fear During Respiratory Panel Removal in Children: A Randomized Controlled Study
Respiratory panel collection is a commonly used diagnostic procedure in children with suspected respiratory tract infections; however, it is often perceived as painful and distressing.
- Conditions
- Procedural Pain, Fear Anxiety, Children
- Trial name
- NCT07319806
- Testing
- Palm Stimulator, Stress Ball
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Sepsis
TRIM25 in Septic Patients
Sepsis is a life-threatening condition caused by the body's overwhelming response to infection, which can lead to organ damage and failure.
- Trial name
- NCT07320638
- Testing
- Gene and Inflammatory Marker Analysis in Sepsis
- Where
- China
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Cardiovascular Abnormalities, Arterial Blood Pressure
Multicenter Study on Cardiovascular and Metabolic Complications in Patients With Biochemically Silent Pheochromocytomas and Paragangliomas
The aim of the study is to characterise the cardiovascular and metabolic complications pre- and post-surgery of patients with biochemically negative PPGL and to compare them with normal individuals and patients with secreting…
- Conditions
- Cardiovascular Abnormalities, Arterial Blood Pressure, Heart Rate, Congestive Heart Failure Chronic
- Trial name
- NCT07316075
- Where
- Greece
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Laikο General Hospital, Athens
Gonad Regulating Hormone Adverse Reaction, Analgesic Adverse Reaction
Neurobehavioral Development in Toddlers and Preschoolers in Relation to Prenatal Exposure of Mild Analgesics (NeuroToP - a COPANA Follow up)
Fundamental aspects of both neurological and reproductive function are established in fetal life, and there is a present increased awareness of the potential effects of fetal exposures on neurodevelopmental and reproductive…
- Conditions
- Gonad Regulating Hormone Adverse Reaction, Analgesic Adverse Reaction, Developmental Disability, Adhd
- Trial name
- NeuroToP (NCT07316387)
- Where
- Denmark
- Volunteers
- 685 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Periodontitis Stage II
Melatonin Loaded in Injectable Platelet-Rich Fibrin in the Management Periodontitis
melatonin loaded in injectible platelet rich fibrin in treatment of periodontitis
- Trial name
- NCT07316582
- Testing
- Melatonin-Loaded Injectable Platelet-Rich Fibrin, injectible platelet rich fibrin (i-PRF )
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Healthy Individuals (Controls), PRIMARY HYPERTENSION PATIENT
The Effect of Motivational Interviewing on Knowledge, Self-Efficacy, and Treatment Adherence in Patients With Primary Hypertension Living in Semi-Rural Areas
This study is a single-center, single-blind, parallel-group randomized controlled trial designed to examine the impact of a Health Belief Model (HBM)-based motivational interviewing (MI) intervention on knowledge level…
- Trial name
- NCT07307924
- Testing
- Motivasyonel görüşme
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Spinal Column, Lumbar Puncture
Comparison of Lateral Decubitus and Upright Sitting Positions in Measuring Intervertebral Space Via Ultrasound in Obese Volunteers
The aim of the study is to compare the lateral decubitus and upright sitting positions in determining the intervertebral space measured by ultrasound in participants whose body mass index was greater than 30 and older than…
- Conditions
- Spinal Column, Lumbar Puncture, Ultrasonography, Position
- Trial name
- NCT07315451
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital
Dental Implants, Dental Prosthesis, Implant-Supported
Clinical Evaluation of a Hyperbolic Paraboloid Triple-Abutment on Morse Taper Dental Implants
This prospective clinical study aims to evaluate the clinical and radiographic outcomes of a novel triple-abutment system with hyperbolic paraboloid geometry installed on Morse taper dental implants.
- Trial name
- NCT07310979
- Testing
- Triple-Abutment System with Hyperbolic Paraboloid Geometry
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Healthy Subjects
Clinical Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics of HSK31858 in Healthy Subjects
This is a single-center, open-label, two-period, fixed-sequence clinical study to evaluate the effect of Itraconazole on the pharmacokinetics of HSK31858 in healthy subjects
- Trial name
- NCT07134465
- Testing
- HSK31858 Tablets and Itraconazole Capsules
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
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