Clinical trials: sponsored by Baylor Research Institute
Colorectal Cancer (CRC) Screening
Smartphone-enabled Hybrid Identification of Early CoLorectal Disease Using Blood-Based Cancer Testing Across TeXas
The goal of this prospective implementation study is to understand the impact of a blood-based screening test (BBST) for colorectal cancer (CRC) on patient acceptability of and adherence to CRC screening as well as the rate of…
- Trial name
- SHIELD-TX (NCT07398456)
- Testing
- Educational Information via Smartphone App
- Where
- United States
- Volunteers
- 5,500 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Chronic Disease, Quality of Life
Expanded Population Health Model Evaluation
This study will evaluate the impact of a comprehensive wellness and social determinants of health intervention on cardiovascular health in a community setting of the Bonton neighborhood.
- Trial name
- NCT06044831
- Testing
- Expanded Population Health Model
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Aging, Longevity
Psilocybin Effects on Healthy Aging Biomarkers and Purpose in Life
The LONG-LIFE study is a randomized Phase I, dose-ranging trial designed to evaluate whether psilocybin impacts aging-related biomarkers, cognitive function, and purpose/meaning in life in medically stable older adults.
- Conditions
- Aging, Longevity, Biomarkers of Aging
- Trial name
- LONG-LIFE (NCT07719088)
- Testing
- Psilocybin (Usona Institute)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Charles Raison
Rare Diseases
Genetic Study to Determine the Cause of Birth Defects in Newborns in Texas
The purpose of this study is to provide advanced genetic testing and virtual consultations for seriously ill newborns in hospitals in Texas with fewer resources, especially along the Texas-Mexico border.
- Trial name
- MAGNET (NCT07102966)
- Testing
- Rapid whole genome sequencing
- Where
- United States
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Covid19
COVID-19 Citizen Science Expansion Project
COVID-19 Citizen Science (CCS), launched in March 2020, supports collaborative research on symptoms, risk factors, surveillance, biomarkers and testing for COVID-19 using the Eureka Research Platform.
- Trial name
- NCT05548803
- Where
- 9 sites in United States
- Volunteers
- 52,351 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Tuberculosis, Diagnoses Disease
Evaluating a New Stool Based qPCR for Diagnosis of Tuberculosis in Children and People Living With HIV
Stool4TB aims to evaluate an innovative stool-based qPCR diagnostic platform (with the capacity to become a POC diagnostic tool) in the high TB and HIV burden settings of Mozambique, Eswatini and Uganda, under the hypothesis that…
- Trial name
- Stool4TB (NCT05047315)
- Where
- 3 sites in Eswatini, Mozambique and 1 more
- Volunteers
- 1,967 people, healthy volunteers welcome
- Sponsor
- Barcelona Institute for Global Health
Hypertension, African Americans
Giving a Low Carbohydrate Diet to Overcome Hypertension
This study will test the preliminary efficacy of adding a very low carbohydrate dietary intervention to the evidence-based DPP-GLB on blood pressure reductions for lower-income AA men and women in a community-based clinic.
- Conditions
- Hypertension, African Americans, Diet, Carbohydrate-Restricted, Risk Reduction Behavior
- Trial name
- GLOH (NCT04230928)
- Testing
- Very low carbohydrate diet, Standard DPP-GLB diet, Standard DPP-GLB program modules
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Sturge-Weber Syndrome
Innovative Approaches to Gauge Progression of Sturge-Weber Syndrome
This study has three aims that hope to expand the knowledge on the cause of Sturge-Weber Syndrome (SWS) and improve clinical care of Sturge-Weber Syndrome patients.
- Trial name
- NCT01425944
- Where
- 7 sites in United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Research Awareness, Qualitative Research
Connect Qualitative Interviews
Goal of the study is to conduct Qualitative Interviews to identify and address barriers to study enrollment from various communities in order to increase the effectiveness and reach of our research to all people in the USA.
- Trial name
- NCT07444411
- Testing
- Qualitative Interview, Qualitative Survey, Survey using a questionnaire.
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Cataract Diabetic, Macula Edema
Dextenza vs Prednisolone Acetate After Cataract Surgery for Patients With Diabetes
This study aims to compare the effectiveness of Dextenza vs standard of care prednisolone taper after cataract surgery in diabetic patients with regards to controlling post-op inflammation at post-op days 7, 14, and 30.
- Trial name
- NCT04977427
- Testing
- Dextenza 0.4Mg Ophthalmic Insert, Prednisolone Acetate 1% Oph Susp
- Volunteers
- healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Concussion, Mild Traumatic Brain Injury
Implementation of an Evidence-Based Educational Resource for Children With Mild Traumatic Brain Injury
The goal of this prospective, observational study is to (1) collaborate with our stakeholders to identify essential mTBI-information from existing evidence-based materials to develop a Post-mTBI Educational Resource for children…
- Trial name
- POCKIT (NCT07414303)
- Testing
- Post-mTBI Educational Resource
- Where
- 3 sites in United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Diabetes, Hypertension
The Integrated Population (I-POP) Health Trial
The primary aim of this study is to determine whether community health worker (CHW) navigation improves outcomes of chronic disease and chronic disease risk factors in a low-income, primarily ethnic minority population when…
- Conditions
- Diabetes, Hypertension, Chronic Kidney Diseases, Obesity
- Trial name
- I-POP (NCT04761016)
- Testing
- Usual Care, I-POP + CHW navigation
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
PTSD, Alcohol Use Disorder
Peer Delivered, Emotion Regulation-Focused Mental Health Prevention Training for Fire Fighter Trainees
The goal of this clinical trial is to determine if a peer-delivered emotion regulation training (Brief-Unified Protocol) workshop is effective for preventing posttraumatic stress and other psychological health symptoms in…
- Conditions
- PTSD, Alcohol Use Disorder, Depression, Anxiety
- Trial name
- PEER UP (NCT06290778)
- Testing
- Brief Unified Protocol, Psychoeducation
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Return to Sport
Clinical Assessment of Sports Exertion
The Clinical Assessment for Sports Exertion (CASE) addresses the physical performance of athletes by quantifying physiological and symptomatic responses to dynamic exertion.
- Trial name
- CASE (NCT05013307)
- Testing
- CASE
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Living Liver and Kidney Donors
Living Organ Donor Recovery Enhancement Program
The purpose of the study is to test if using these living donor-specific pre-transplant resources would lead to a better and faster recovery post-transplant.
- Trial name
- NCT03865264
- Testing
- Recovery Enhancement Program
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Tobacco Use, Alcohol Abuse
Tobacco, Alcohol, Prescription Drug, and Illicit Substance Use- Electronic Spanish Platform
The goal of this study is to validate the TAPS-ESP as a screen and assessment that can be used in primary care for the screening and treatment of substance use.
- Conditions
- Tobacco Use, Alcohol Abuse, Prescription Drug Abuse, Substance Use
- Trial name
- TAPS-ESP (NCT05476588)
- Testing
- Screening
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Uterine Atony
Exploration and Determination of Genomic Markers Predictive of Uterine Atony
The primary objective of this study is to determine whether there are markers in the tissue of atonic uteri, and in the patients' plasma that would help identify patients likely to suffer postpartum hemorrhage due to uterine…
- Trial name
- NCT03413917
- Testing
- Analysis of genomic markers in uterine atony
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Human Papillomavirus Infection
Throat and Other HPV-Related Cancers in Men: Identifying Them Early
This trial studies the screening of human papillomavirus (HPV)-related oropharyngeal and anogenital cancers. Learning the relationship between HPV and cancer risk in men who test positive for HPV antibodies or circulating HPV DNA…
- Trial name
- TRINITY (NCT02897427)
- Testing
- Biomarker Analysis, Biospecimen Collection, Ultrasonography
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Blood Loss, Dysfunctional Labor
Cooling the Uterus in C-section After Dysfunctional Labor
The objective of the study is to demonstrate whether cooling the uterine smooth muscle during cesarean section (following delivery of the fetus) will promote better uterine contraction and involution resulting in lower blood…
- Conditions
- Blood Loss, Dysfunctional Labor, Uterine Atony
- Trial name
- NCT02910115
- Testing
- Cold laparotomy sponges, Pitocin
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Mild Cognitive Impairment, Alzheimer Disease
Discovery of Novel Biomarkers That Will Lead to the Early Detection of Alzheimer's Disease
This study will perform a targeted metabolic analysis in blood and urine samples from subjects attending the Baylor AT\&T Memory Center.
- Trial name
- BVB (NCT03136679)
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute