Clinical trials: sponsored by St. Olavs Hospital
Pre-Eclampsia
Screening for Preeclampsia in Norway With Aspirin Discontinuation at 24-28 Weeks
Study population Around 3500 pregnant women attending a routine ultrasound scan at 11-14 weeks at St. Olavs hospital, Trondheim, Norway.
- Trial name
- PEScreenNor (NCT06108947)
- Testing
- Aspirin
- Where
- Norway
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Heart Failure
Deep Learning-Based Automated Pressure-Strain Loop Analysis
Noninvasive left ventricular pressure-strain loop analysis estimates myocardial work from longitudinal strain, brachial systolic blood pressure, and cardiac valve-event timing.
- Trial name
- NCT07850726
- Testing
- Sustained Isometric Handgrip Exercise, Semi-Supine Bicycle Exercise
- Where
- Norway
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Amyotrophic Lateral Sclerosis, Motor Neuron Disease
Effects of Long Term Ventilation Support on the Quality of Life of ALS Patients and Their Families
Amyotrophic lateral sclerosis (ALS) is a serious rapidly progressive disease of the nervous system. The average survival from the time of diagnosis is two to three years.
- Conditions
- Amyotrophic Lateral Sclerosis, Motor Neuron Disease, Nervous System Diseases, Spinal Cord Diseases
- Trial name
- ALS-LTMV (NCT05744310)
- Testing
- Long term mechanical ventilation support, No long term mechanical ventilation support
- Where
- 9 sites in Norway
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Psychotic Disorder, SCHIZOPHRENIA 1 (Disorder)
Ultrasound Assessment of Gluteal Muscle in Patients Receiving Depot Antipsychotics and Healthy Volunteers
This observational study will use ultrasound to assess the gluteal musculature in patients receiving depot antipsychotic medication and in healthy volunteers.
- Conditions
- Psychotic Disorder, SCHIZOPHRENIA 1 (Disorder), Intramuscular Injection
- Trial name
- ULPSYK (NCT07815587)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Healthy Volunteers
Mapping of Cardiac Power in Healthy Humans and Testing of a New Blood Pressure Sensor
Brief Summary: The study will record hemodynamic data from 20 healthy volunteers at rest and during moderate bicycle exercise in the recumbent and half sitting position for the following purposes: Sub-study 1 Testing the overall…
- Trial name
- NCT05008133
- Testing
- Bicycle exercise
- Where
- Norway
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Chronic Migraine
Prophylactic Treatment With Atorvastatin for Chronic Migraine (ChronicStatinMig)
The main objective of this study is to see whether the favorable preventative effect of Atorvastatin 40mg per day in episodic migraine, that was found previously in three smaller randomized controlled cross-over studies, can be…
- Trial name
- NCT06485336
- Testing
- Atorvastatin 40mg
- Where
- 6 sites in Norway
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Insomnia Disorder, Circadian Rhythm Sleep Disorder
The Sleep Clinic Outcome and Practice Study
The goal of this clinical trial is to explore the outcome and practice treatment for sleep-wake disturbances in a Sleep Clinic. The main questions it aims to answer are: What is the practice (timing and duration of treatment…
- Trial name
- SUP (NCT06669507)
- Testing
- Chronotherapy, Cognitive Behavioral Therapy for Insomnia
- Where
- Norway
- Volunteers
- 3,400 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Episodic Migraine
Prophylactic Treatment With Atorvastatin for Episodic Migraine.
The main objective of this study is to see whether the favorable preventative effect of Atorvastatin 40mg per day in episodic migraine, that was found previously in three smaller randomized controlled cross-over studies, can be…
- Trial name
- EStatinMig (NCT06248671)
- Testing
- Atorvastatin 40mg, Atorvastatin 20mg
- Where
- 6 sites in Norway
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Post Stroke Epilepsy, Stroke
Predisposing Factors for Post-stroke Epilepsy
The goal of this observational study is to learn about epilepsy after a stroke (post-stroke epilepsy). The main questions it aims to answer are: What make some patients develop epilepsy after a stroke? Does sleep have an impact…
- Conditions
- Post Stroke Epilepsy, Stroke, Epilepsy, Seizures
- Trial name
- PRESTEP (NCT05864547)
- Where
- Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Asthma, Occupational, Hypersensitivity
Measures for Bioaerosol Reduction in the Salmon Industry
Workers in the salmon industry are at risk of developing allergies and respiratory diseases, including asthma, due to occupational exposure to bioaerosols, i.e.
- Trial name
- SHInE (NCT05039229)
- Testing
- Nozzles (NZ), Cleaning of surfaces (CS)
- Where
- Norway
- Volunteers
- 1,113 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Preterm, Patent Ductus Arteriosus
NeoDoppler: New Ultrasound Technology for Continuous Monitoring of Cerebral Circulation Pilot
Non-invasive tools for monitoring of course of disease are important and necessary in the treatment of pre-term/premature infants and sick neonates.
- Conditions
- Preterm, Patent Ductus Arteriosus, Sepsis, Asphyxia
- Trial name
- CE-NeoDoppler (NCT06646250)
- Testing
- NeoDoppler - CE certified
- Where
- Norway
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Preeclampsia
Biological Changes Associated With High Risk of Preeclampsia in Nulliparous Women
Primary outcome 1. to identify biological changes in nulliparous women at high risk for preeclampsia defined by combined screening by Fetal Medicine Foundation (FMF) 2.
- Trial name
- PRERISK (NCT06200571)
- Where
- 2 sites in Norway
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Breast Milk Collection, Overweight and Obesity
Acute Effects of Endurance Exercise on Breast Milk Composition in Women With Overweight/Obesity
The investigators will determine the acute effect of exercise on breastmilk composition. Participants will come in to the lab on three different days, out of which they will exercise on two of these days and rest in the lab on…
- Trial name
- YT (NCT05745922)
- Testing
- Moderate intensity exercise, High intensity exercise
- Where
- Norway
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Lipedema
The National Lipedema Study
Lipedema is a chronic condition with a symmetrical accumulation of painful fatty tissue primarily affecting the limbs, sparing hands, feet and trunk.
- Trial name
- NCT05284266
- Testing
- Liposuction early, Liposuction late, Standard conservative treatment
- Where
- Norway
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Haraldsplass Deaconess Hospital
Alcohol Consumption, Psychoactive Substance Use
AlcoTail - Implementation of Tailored Interventions
This study aims to investigate the implementation and real-world effects of an intervention for harmful use of alcohol and psychoactive medicinal drugs among hospital inpatients.
- Trial name
- NCT04957628
- Testing
- Harmful alcohol use treatment, Non-prescribed psychoactive medicinal use treatment
- Where
- Norway
- Volunteers
- 4,200 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Atrial Fibrillation
The NORwegian Atrial Fibrillation Self-SCREENing
Atrial fibrillation (AF) is common, increases the risk of mortality, stroke and heart failure, and portending significant burden to patients, societal health and health economy. One of three AF cases are undiagnosed.
- Trial name
- NORSCREEN (NCT05914883)
- Testing
- Long-term continuous ECG monitoring
- Where
- Norway
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Arthritis Knee, Arthroplasty
Robotic Assisted Knee Arthroplasty - Retain the Anterior Cruciate Ligament or Not
The goal of this clinical trial is to compare the function of the knee after retaining or sacrificing the anterior cruciate ligament in robotic assisted knee arthroplasty.
- Conditions
- Arthritis Knee, Arthroplasty, Gait Analysis
- Trial name
- NCT06264999
- Testing
- Journey II CR, Journey II XR
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Pelvic Floor; Rupture, Childbirth Problems
Levator Hiatal Dimensions and Mode of Delivery
The aim of this observational study is to learn about how muscle dimensions of the pelvic floor measured during pregnancy in primigravida impact birth mecanics and mode of delivery. Tha main aims are to 1.
- Conditions
- Pelvic Floor; Rupture, Childbirth Problems, Pelvic Floor Dyssynergia
- Trial name
- LEVDIM (NCT05849584)
- Testing
- Transperineal ultrasound
- Where
- 2 sites in Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Hyperaldosteronism
Primary Aldosteronism in Western Norway
In this study the investigators aim to identify and include consecutively patients with primary aldosteronism (PA) diagnosed in the Western and Mid-parts of Norway, to describe the characteristics of these patients, to explore…
- Trial name
- NCT02832388
- Where
- 2 sites in Norway
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Prostate Cancer, Magnetic Resonance Imaging
MR Fingerprinting for Diagnostic of Prostate Cancer
The diagnostic pathway for suspected prostate cancer relies greatly on radiological imaging. Establishment of magnetic resonance fingerprinting (MRF) has the potential to significantly improve patient experience and outcomes.
- Trial name
- NCT05498623
- Where
- Norway
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology