Clinical trials: sponsored by University of Bern
Parental Stress, Communication Disorder, Childhood
Pediatric Research in the Outpatient Setting CoHort
Though primary care pediatricians (PCPs) and general practitioners solve 90% of children's health problems without referral to specialized care (about 10% of total health expenditures) there is little data on the common health…
- Conditions
- Parental Stress, Communication Disorder, Childhood, Development and Health
- Trial name
- PROS-CH (NCT07911228)
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
General Mental Health and Well-Being, Mental Disorders
PREWELL Digital Well-being Promotion Intervention With the BitHabit App
Mental wellbeing is a major public health concern, and digital interventions have emerged as a scalable approach for promoting mental well-being and healthy lifestyle behaviors.
- Conditions
- General Mental Health and Well-Being, Mental Disorders, Common Mental Disorders (CMD)
- Trial name
- PREWELL (NCT07868146)
- Testing
- Digital wellbeing promoting intervention with the BitHabit app
- Where
- Finland
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Dental Implant Failed
Clinical Performance of Dual-cantilevered Single-implant Bridge
The study aims to evaluate the clinical performance (implant and prosthetic survival/ success rates) of a novel implant-supported fixed dental prosthesis design: the dual-cantilevered single implant bridge (T-Bridge) made out of…
- Trial name
- T-bridge (NCT06099717)
- Testing
- Dual-cantilevered implant bridge, 3-unit iFDP
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
Gingivitis Infection
Chlorhexidine (CHX) Mouthwash With or Without an Anti-Discoloration System (ADS) During Experimental Gingivitis
Recently, a chlorhexidine product with an anti-discoloration system (ADS) was launched in the market. A comparative study was done to confirm the effectiveness of 0.2% chlorhexidine with ADS. The study was single-blinded.
- Trial name
- NCT07696364
- Testing
- Experimental gingivitis model
- Where
- Switzerland
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Bern
Blood Glucose Concentration, Glycemic Index
Non-alcoholic, Fiber-enriched Beer and Its Effect on Blood Glucose Concentration
This study examines how various non-alcoholic beverages affect blood sugar levels. The beverages are a non-alcoholic, fiber-enriched beer, a conventional non-alcoholic beer, and a sugar solution.
- Conditions
- Blood Glucose Concentration, Glycemic Index, Dietary Fiber, Non-alcoholic Beer
- Trial name
- NCT07131904
- Testing
- non-alcoholic, fiber-enriched beer (FEB), conventional, non-alcoholic beer, glucose solution
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- David Faeh
Low Back Pain
Back Beliefs Among the General Population
In the current study we aim to evaluate the effects of a short educational video on improving the belief that "the back is fragile and needs to be protected" among the German speaking Swiss general population.
- Trial name
- NCT06104995
- Testing
- Interventional video, Control video
- Where
- Switzerland
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- Bern University of Applied Sciences
Hyperthermia, Chronic Primary Pain
Hyperthermia in Patients With Chronic Primary Pain - Effects on Thermoregulation, Somatosensory System and Movement Evoked Pain
This study, in a quasi-experimental matched two-group pre-post design, investigates the effect of serial water-filtered whole-body hyperthermia on circadian core body temperature, the somatosensory system (nociception) and the…
- Conditions
- Hyperthermia, Chronic Primary Pain, Widespread Pain, Muscular Disease
- Trial name
- HYPPRI-1 (NCT07101978)
- Testing
- serial whole body hyperthermia
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bern University of Applied Sciences
Contrast Enhanced Ultrasound, Ultrasonic Diagnosis
International Delphi Study to Develop Standardized Quality Criteria and a Rating Tool for Liver CEUS Image Quality Assessment
This study aims to establish international consensus-based quality criteria for contrast-enhanced ultrasound (CEUS) examinations of the liver and to develop a standardized tool for assessing CEUS image and examination quality.
- Conditions
- Contrast Enhanced Ultrasound, Ultrasonic Diagnosis, Liver
- Trial name
- ICON LiverCEUS (NCT07656181)
- Where
- Switzerland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Bern
Depressive Disorder, Major Depressive Disorder, Healthy Volunteer
Exploring the Role of the Prefrontal Cortex in Decision-Making
The goal of this study is to examine whether high-definition transcranial direct current stimulation (HD-tDCS) can influence decision-making for emotionally valenced content in younger and older adults, with or without major…
- Conditions
- Depressive Disorder, Major Depressive Disorder, Healthy Volunteer, Aging
- Trial name
- NCT07080489
- Testing
- Active high-definition transcranial direct current stimulation (HD-tDCS) - anodal F3/F4, Active high-definition transcranial direct current stimulation (HD-tDCS) - anodal F3/ kathodal F4
- Where
- Switzerland
- Volunteers
- 444 people, healthy volunteers welcome
- Sponsor
- University of Bern
Fear of Falling
Feasibility of Aktiv Gegen Sturzangst (AGES) in Assisted Living Facilities
Aktiv Gegen Sturzangst (AGES) is a multicomponent group intervention combining cognitive behavioral therapy and structured exercise to address fear of falling in older adults receiving services from assisted living facilities.
- Trial name
- AGES (NCT07787819)
- Testing
- Multicomponent fear of falling intervention
- Where
- 3 sites in Switzerland
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Eric Lenouvel
Multiple Sclerosis, Long Covid
Fatigue Investigation Using Digital Outcomes
This study investigates objective methods to measure and monitor fatigue in patients with post-COVID-19 condition (long COVID) and multiple sclerosis (MS), and includes a group of healthy volunteers for comparison.
- Conditions
- Multiple Sclerosis, Long Covid, Healthy
- Trial name
- FIDO (NCT07783074)
- Where
- 6 sites in Switzerland
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Liliana Barrios
Dental Implants
Implant-related Outcomes in the Context of Maxillary Sinus Lifting
The population of interest will be recruited out of a cohort of patients who were initially treated at the Department of Oral Surgery and Stomatology between 1997 and 2001.
- Trial name
- NCT06647381
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
Mild Cognitive Impairment (MCI) Amnestic, Mild Cognitive Impairment
Mental Strategy Training in Mild Cognitive Impairment
This study aims to reduce hippocampal activity in people at high risk of developing Alzheimer's disease (AD) and aims to examine whether this improves their episodic memory performance.
- Trial name
- NCT07718945
- Testing
- Mental Strategy Training
- Where
- Switzerland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Jessica Peter
Driving Under the Influence, Cannabis-impaired Driving
In-Vehicle Real-Time Cannabis Influenced Driving Detection
The goal of this clinical trial is to evaluate whether in-vehicle sensor data can be used to detect cannabis-impaired driving in healthy adult recreational cannabis users.
- Trial name
- REVELIO (NCT07401628)
- Testing
- Cannabis (THC)
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Bern
Burnout Syndrome, Depression Disorder
The COMET Study: a Prospective COhort of MEdical residenTs to Assess Professional, Personal and Psychological Trajectories of Residents in General Internal Medicine
Introduction. Switzerland, like most Western countries, faces a paradox: an ageing, multimorbid population needs general internal medicine (GIM) physicians more than ever, yet fewer young doctors choose - and stay in - the…
- Conditions
- Burnout Syndrome, Depression Disorder, Insomnia, Perceived Stress
- Trial name
- COMET (NCT07707453)
- Where
- 3 sites in Switzerland
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Fribourg
Loneliness, Poverty
Alleviating Loneliness in Older Adults Living in Poverty: A Multi-level Intervention
The study aims to reduce loneliness among Hong Kong Chinese older adults living in poverty with a multi-level intervention involving components at the individual, interpersonal, and community levels.
- Trial name
- NCT07123064
- Testing
- Individual Level, Interpersonal Level, Community Level
- Where
- Hong Kong
- Volunteers
- 1,344 people, healthy volunteers welcome
- Sponsor
- Education University of Hong Kong
Periodontitis, Periodontal Inflammation
PRF as Adjunct to Subgingival Instrumentation in Step 2 Periodontal Therapy
Periodontitis is characterized by a chronic, multifactorial inflammatory process driven by dysbiotic plaque biofilms. It is recognized as the most common chronic inflammatory non-communicable disease in humans.
- Conditions
- Periodontitis, Periodontal Inflammation, Periodontal Attachment Loss
- Trial name
- PRFSTEP2 (NCT07013682)
- Testing
- PRF as adjunct to non-surgical mechanical debridement, Control, non-surgical mechanical debridement alone
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Bern
Childhood Cancer
Swiss Childhood Cancer Survivor Study
The SCCSS is designed to investigate which long-term effects childhood cancer and its treatment have on survivors, and includes those who were under 20 years when they were diagnosed.
- Trial name
- SCCSS (NCT03297034)
- Where
- Switzerland
- Volunteers
- 4,136 people, healthy volunteers welcome
- Sponsor
- University of Bern
Remote Cognitive Training, Alzheimer Disease
Remote Technologies in Early Stages of Alzheimer's Disease
The investigators are adapting a tablet-based cognitive training program for Alzheimer's disease (AD) by focusing on specific cognitive components.
- Conditions
- Remote Cognitive Training, Alzheimer Disease, Mild Cognitive Impairment, Old Age; Dementia
- Trial name
- NCT07521865
- Testing
- App-based cognitive training
- Where
- Switzerland
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Bern
Connective Tissue Graft, Volume Collagen Matrix Xenograft
Volumetric Dimensional Changes After Surgical Pontic Site Development Procedures With Connective Tissue Graft or Collagen Matrix
The aim of this research project is to compare two surgical procedures to improve soft tissue volume. Both procedures have already been validated, but despite their great clinical relevance, little data exists in the literature.
- Trial name
- NCT06335628
- Testing
- Geistlich Fibro-Gide®
- Where
- Switzerland
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Bern