Clinical trials: sponsored by University of Utah
Pain, Postpartum Depression
Ketamine Pharmacokinetics and Pharmacodynamics for Postpartum Depression and Pain After Cesarean Delivery
The purpose of this study is to identify pharmacokinetics of postpartum ketamine infusion. This study will assess ketamine kinetics and metabolism in this setting.
- Trial name
- PREPARE-2 (NCT06767566)
- Testing
- Ketamine (Ketalar)
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Utah
Financial Burden, Health Behavior
Economic Empowerment and Health Promotion of Uganda Grandmother-caregivers.
Background: There are an estimated 163 million children worldwide who are under the care of their grandparents or other relatives.
- Conditions
- Financial Burden, Health Behavior, Social Support
- Trial name
- BAJJAJJA (NCT07011264)
- Testing
- The BAJJAJJA intervention
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Utah
Obstruction Airway
Positive Airway Pressure (PAP) System Evaluation in Volunteers
This study will test the control and measurements of a new system for airway support in healthy volunteers. The goals of the study are to evaluate how accurately the system can stabilize airway pressure to a desired level…
- Trial name
- NCT07246538
- Testing
- CPAP
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Utah
Skin Cancer Prevention, Sun Safety
Regional Efforts to Advance School-based Sun Safety Through Collaboration for Skin Health
This project will deliver a sun safety education presentation to high schools in the mountain west (e.g., Montana, Wyoming, and Idaho) who are at high melanoma risk.
- Trial name
- REACH West (NCT07904572)
- Testing
- REACH West
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Utah
HPV Vaccination, Uptake Vaccination
PREVENT HPV -Related Cancers Trial
This study will serve as one of the first to develop and test the effectiveness of strategies to promote HPV vaccination among diverse rural parents and caregivers of children ages 9-17 years in the Mountain West.
- Conditions
- HPV Vaccination, Uptake Vaccination, Series Completion
- Trial name
- NCT07217145
- Testing
- PREVENT
- Where
- United States
- Volunteers
- 1,455 people, healthy volunteers welcome
- Sponsor
- University of Utah
Colorectal Cancer
Social Media and Cancer Screening Information
NORC/AmeriSpeak will recruit participants who meet the study criteria and invite them to complete a 15-minute survey. Participants will be randomly assigned to one of five conditions, with approximately 400 people in each…
- Trial name
- NCT06712901
- Testing
- Median Ranked Cancer Screening Messaging, Overall Preferred Cancer Screening Messaging, Black American Preferred Cancer Screening Messaging
- Where
- United States
- Volunteers
- 2,030 people, healthy volunteers welcome
- Sponsor
- University of Utah
HIV Infections
Screen Smart: Using Digital Health to Improve HIV Screening and Prevention
The goal of this interrupted time series quasi-experimental design study is to implement universal opt- out HIV testing and linkage to HIV preventive care in 15-21 year old adolescents visiting the pediatric emergency department…
- Trial name
- Screen Smart (NCT06003192)
- Testing
- Universal Opt-out HIV Screening
- Where
- 4 sites in United States
- Volunteers
- 63,000 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Peripheral Neuropathy
Diode Laser as a Biomarker for Neuropathic Pain of Peripheral Origin.
The R61 will perform a four-part double-blind randomized crossover study transitioning from a pretreatment baseline phase, to randomized treatment with either lidocaine or an identical placebo patch, washout, and alternate arm.
- Trial name
- DLss (NCT06030297)
- Testing
- Diode Laser fiber type Selective Stimulator, ZTlido 1.8 % Topical System, PeriCam PSI NR
- Where
- 2 sites in United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of Utah
Cancer
Cancer Prevention for Young Rural Adults
Young adults aged 18-26 engage in a number of behaviors that increase their risk of developing cancer later in life including sedentary lifestyles, unhealthy eating, nicotine produce us, heavy drinking of alcohol, increased UV…
- Trial name
- NCT05618158
- Testing
- 4 Corners Rural Health Cancer Prevention
- Where
- 5 sites in United States
- Volunteers
- 1,796 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Prediabetic State, Life Style
PreventT2 Together: Examining the Efficacy of Couple-based Lifestyle Intervention to Prevent Type 2 Diabetes
Nearly half of adults in the United States have or are at risk of developing type 2 diabetes. The overall goal of this community-engaged research is to examine the efficacy of an innovative couple-based lifestyle intervention to…
- Conditions
- Prediabetic State, Life Style, Intervention Study, Social Support
- Trial name
- PT2T (NCT06690788)
- Testing
- Individual intervention condition (PreventT2), Couple-based intervention condition (PreventT2 Together; couple-based adaptation of 2021 PreventT2; approved by the CDC in November 2022 as an Alternate Curriculum for use in the NDPP)
- Where
- United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- University of Utah
Vaccine Confidence, Adolescent Vaccination
Tailored Vaccine Messaging for Parents/Caregivers of Adolescents
his study will evaluate whether tailored vaccine messaging improves vaccination-related outcomes among parents and caregivers of adolescents.
- Conditions
- Vaccine Confidence, Adolescent Vaccination, Vaccine Uptake
- Trial name
- VACCINE-WEST (NCT07878442)
- Testing
- Tailored Vaccine Messaging, Standard Vaccine Message
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Utah
Pre Diabetic
PASO A PASO: Tailored Diabetes Prevention Program for Spanish-Speaking Communities Feasibility Study
The interdisciplinary and interprofessional community-academic partnership (CAP) has been working with Spanish-speaking H/L Salt Lake City residents and organization leaders to adapt the National Diabetes Prevention Program to…
- Trial name
- NCT07392008
- Testing
- Paso a Paso
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Utah
Tourette Syndrome in Children
Exploring the Role of Neuroactive Steroids in Tourette Syndrome
Tourette syndrome (TS) is a disabling neurodevelopmental disorder characterized by motor and phonic tics. The studies proposed in this application will explore the endocrine mechanisms underlying two of the least well-understood…
- Trial name
- NS in TS (NCT05281445)
- Testing
- Tic suppression task
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Utah
Lung Cancer
Population Health Management -Increase Lung Cancer Screening in Community Health Centers (LungSMART)
The long-term goal of Lung Sequential Multiple Assignment Randomized Trial (LungSMART) Utah is to increase the reach of Low-Dose Computed Tomography (LDCT) screening for lung cancer (hereafter referred to as Lung Cancer Screening…
- Trial name
- LungSMART (NCT07599943)
- Testing
- Text Messages (TM+), Chatbot (CA), Video (VID)
- Where
- United States
- Volunteers
- 18,894 people, healthy volunteers welcome
- Sponsor
- University of Utah
Cancer Survivorship
Improving Radon Education and Awareness in Cancer Patients and Their Extended Community
Clinical appointments are an opportunity to provide cancer survivors (defined as patients and survivors) and people in their communities (e.g. caregivers, family members, friends) with education about radon and radon testing.
- Trial name
- NCT07712133
- Testing
- Educational Presentation
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Utah
Overweight and Obesity
Circadian Timing, Information Processing and Energy Balance Study
This study design will test biological and behavioral mechanisms in the cross-sectional analyses and determine the prospective effects of circadian alignment and sleep on changes in cardiometabolic risk factors.
- Trial name
- TIME (NCT04759755)
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- University of Utah
Lung Cancer, Lung Nodule
SPARC - Screening for Lung Cancer With Platelets Via an AI-enabled RNA-based Classifier
The purpose of this study is to test whether combining a unique analytical approach with changes in platelet RNA expression accurately diagnoses lung cancer.
- Trial name
- SPARC (NCT07460440)
- Testing
- Platelet RNA-based assay
- Where
- 2 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Utah
Chronic Obstructive Pulmonary Disease, Pulmonary Artery Hypertension
: Vascular Function in Health and Disease
Many control mechanisms exist which successfully match the supply of blood with the metabolic demand of various tissues under wide-ranging conditions.
- Conditions
- Chronic Obstructive Pulmonary Disease, Pulmonary Artery Hypertension, Heart Failure, Hypertension
- Trial name
- NCT02966665
- Testing
- Maximum Exercise Tests, BH4, L-NMMA, Vitamin C, Vitamin E, α-Lipoic Acid and L-Ascorbate, BQ-123
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- D. Walter Wray
Social Determinants of Health (SDOH), Digital Health Literacy
The e-SINCERE Study
The e-SINCERE study will evaluate whether providing stable cell phones and digital navigation assistance helps patients overcome ICT barriers and connect more successfully with community services.
- Conditions
- Social Determinants of Health (SDOH), Digital Health Literacy, Health Services Utilization
- Trial name
- e-SINCERE (NCT07174466)
- Testing
- Standard Referral to 211, e-SINCERE (Phone Support), e-SINCERE (Digital Navigation)
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Andrea Wallace
Skin Cancer
Mobile Sun Health Intervention EnabLing Daily Protection
The overall purpose of this proposal is to refine a mobile-health (mHealth) system to reduce excessive unprotected sun exposure among young adults.
- Trial name
- mSHIELD (NCT07830394)
- Testing
- Text Message Reminders, Sun Protection Education Modules, Action Planning Module
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Utah