Clinical trials: Aerobic Exercise
Fibromyalgia
Optimized tDCS for Fibromyalgia: Targeting the Endogenous Pain Control System
This trial aims at understanding the mechanisms of optimized transcranial direct current stimulation (tDCS) (16 tDCS sessions combined with exercise)] on pain control.
- Trial name
- NCT03371225
- Testing
- Active tDCS, Active Exercise
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Spaulding Rehabilitation Hospital
Parkinson Disease
Pragmatic Cyclical Lower Extremity Exercise Trial for Parkinson's Disease
Identification of an effective disease-modifying intervention (e.g. pharmaceutical, surgical or behavioral) is an unmet need in Parkinson's disease (PD).
- Trial name
- CYCLE-II (NCT04000360)
- Testing
- High-Intensity Aerobic Exercise (AE), Usual and Customary Care (UCC)
- Where
- 2 sites in United States
- Volunteers
- 256 people
- Sponsor
- The Cleveland Clinic
Cardiovascular Disease
Vivo Heart: Home-Based Virtual Exercise Program for Older Adults With Cardiovascular Disease
This pilot study will assess the feasibility and generate preliminary efficacy data of a novel, synchronous, home-based exercise training program for rural older adults with cardiovascular disease (CVD) using Vivo, an online…
- Trial name
- NCT05972850
- Testing
- Vivo Heart
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Wake Forest University Health Sciences
Osteopenia, Bone Turnover Markers
Effects of Physical Training on Bone Turnover and Quality of Life in Osteopenic Postmenopausal Women.
The aim of our research was to define both in vivo and in vitro whether and to what extent an high-impact exercise program would affect bone cell turnover and improve the QoL in osteopenic postmenopausal women.
- Conditions
- Osteopenia, Bone Turnover Markers, Quality of Life
- Trial name
- NCT03195517
- Testing
- Physical exercise
- Volunteers
- 33 people
- Sponsor
- University Of Perugia
Frailty, Sarcopenic Obesity
Diet and Exercise Plus Metformin to Treat Frailty in Obese Seniors
The continuing increase in prevalence of obesity in older adults including many older Veterans has become a major health concern.
- Conditions
- Frailty, Sarcopenic Obesity, Aging
- Trial name
- DEMFOS (NCT04221750)
- Testing
- Lifestyle therapy, Metformin Hydrochloride, Healthy Lifestyle
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
HIV Infections, Cardiovascular Disease
Myocardial Function & FFA Metabolism in HIV Metabolic Syndrome
We hypothesize that the hearts of HIV+ people with The Metabolic Syndrome use and oxidize fats and sugars inappropriately, and that this may impair the heart's ability to pump blood.
- Conditions
- HIV Infections, Cardiovascular Disease, Insulin Resistance, HIV Lipodystrophy
- Trial name
- WU197 (NCT00656851)
- Testing
- Pioglitazone, Exercise Training
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Central Obesity, Obesity
Aerobic Training and Non-Exercise Physical Activity
This study will determine the health benefits of combining exercise training and increasing the amount of physical activity in daily life on the fat around the abdomen, weight, fitness and sensitivity to insulin.
- Trial name
- I-CAN (NCT02010060)
- Testing
- Aerobic Exercise Training, Aerobic Exercise+ Physical Activity
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- East Carolina University
Type 1 Diabetes
Two Way Crossover Closed Loop Study R-AP vs MPC
An artificial pancreas (AP) is a control system for automatic insulin delivery. The investigators have implemented a missed meal bolus detection algorithm for use within an AP control system.
- Trial name
- NCT05083559
- Testing
- MPC AP algorithm, Robust R-AP algorithm
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Oregon Health and Science University
Type 1 Diabetes
Context Aware Data Gathering Study
Automated Insulin Delivery (AID) systems have now become an important standard-of-care for people with T1D and have demonstrated a reduction, but not elimination, of hypoglycemia during long-term studies.
- Trial name
- NCT04154904
- Testing
- Exercise
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Oregon Health and Science University
Covid-19, Deconditioning
Predictors of Recovery and the App-Facilitated Tele-Rehabilitation (AFTER) Program for COVID-19 Survivors
The aim of this study is to investigate the feasibility (safety, adherence) and initial efficacy (physical function and patient reported outcomes) of a multicomponent tele-rehabilitation program during COVID-19 recovery of…
- Trial name
- AFTER (NCT04663945)
- Testing
- Biobehavioral Tele-rehabilitation Sessions
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Colorado, Denver
Prediabetes
ForgIng New Paths to Prevent DIabeTes (FINDIT)
This study will evaluate the effects of screening for type 2 diabetes mellitus (T2DM) and brief counseling about screening test results on weight and key health behaviors among Veterans with risk factors for T2DM.
- Trial name
- FINDIT (NCT02747108)
- Testing
- Blood Test Group Intervention, Brochure Group Intervention
- Where
- United States
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Prediabetic State
Medium Chain Triglycerides and Aerobic Exercise on Ketone Production in Women With or Without Prediabetes
The aim of this study is to compare the effect on ketone production of dietary an MCT supplement combined or not with physical exercise in two groups of women (N=10/group), healthy adults and patients with prediabetes.
- Trial name
- MCT+AE (NCT02678390)
- Testing
- MCT, MCT+ aerobic exercise, Aerobic exercise
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Type 1 Diabetes
Exercise Detection Study
The risk of hypoglycemia in individuals with type 1 diabetes increases considerably during exercise. As a result, many patients with type 1 diabetes experience fear of and reluctance to pursue physical activity, in order to avoid…
- Trial name
- NCT02688218
- Testing
- Aerobic Exercise, Resistance Exercise
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Type 1 Diabetes
Two Way Crossover Closed Loop Study MPC vs FMPD
An artificial pancreas (AP) is a control system for automatic insulin delivery. Our group has implemented a fading memory proportional derivative controller (FMPD) for use within an AP control system which has been evaluated in…
- Trial name
- NCT04771403
- Testing
- FMPD AP algorithm, MPC AP system, Dexcom G6 Continuous Glucose Monitoring (CGM) System
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Oregon Health and Science University
Aging
The Entorhinal Cortex and Aerobic Exercise in Aging
The overall goal of this study is to examine how regular exercise affects brain function, spatial memory, and virtual navigation. Participation in this research study will take approximately 4 months.
- Trial name
- ECE (NCT02775760)
- Testing
- Cardiovascular endurance, Strength, balance, and flexibility
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Boston University
Traumatic Brain Injury (TBI)
Effect of Exercise Training on Physical, Cognitive, and Behavioral Function in People With TBI
Background: Traumatic brain injury (TBI) often causes problems with moving and balance, and thinking and emotions. Exercise can improve these things in people with other brain damage.
- Trial name
- NCT02504866
- Testing
- Vigorous exercise, Light to moderate exercise
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Obesity and Physical Inactivity in Adolescents
Social Exergaming for Healthy Weight in Adolescent Girls
The purpose is to evaluate the feasibility of a 12-week exergaming dance program for adolescent girls. This study combines dancing, video games, and a full body work-out to test if video games can increase physical activity and…
- Trial name
- Klub Kinect (NCT02003963)
- Testing
- Klub Kinect
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Sedentary Lifestyle
Aerobic Exercise and Cognitive Training in Older Adults
The purpose of this study is to examine the impact of a combined cognitive training and aerobic exercise intervention in sedentary older adults.
- Trial name
- NCT02787655
- Testing
- Aerobic exercise + Cognitive Training Group, Cognitive training Only
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Kyphosis
Study of Hyperkyphosis, Exercise and Function-SHEAF
We propose to conduct a randomized, controlled trial among 100 men and women aged 60 or older with hyperkyphosis to an exercise intervention that includes kyphosis-specific spinal muscle strengthening exercises compared to a…
- Trial name
- sheaf (NCT01751685)
- Testing
- Kyphosis-specific spinal strengthening exercises, Control
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Diabetes Mellitus Type 2
Home Exercise to Enhance Mobility for Older Diabetics
The goal of the proposed research is to test whether a long-term exercise program in sedentary Veterans with diabetes will produce sustained improvement in mobility performance and physical activity.
- Trial name
- NCT01308008
- Testing
- home exercise/physical activity (PA) enhancement program with behavioral support, flex and toning health education program
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- VA Office of Research and Development