Clinical trials: Amlodipine
Hypertension
Anti Inflammatory Treatment of Hypertension
To investigate the anti-inflammatory effect of amlodipine and levamlodipine in the treatment of hypertension
- Trial name
- NCT04740840
- Testing
- Levamlodipine, Amlodipine
- Volunteers
- 200 people
- Sponsor
- Affiliated Hospital of North Sichuan Medical College
Hypertension
Comparison of Optimal Hypertension Regimens
High blood pressure (Hypertension) is extremely common and is a major cause of heart disease, kidney disease and stroke. One in three of the UK (United Kingdom) population will require treatment for hypertension at some point in…
- Trial name
- AIMHY-INFORM (NCT02847338)
- Testing
- Amlodipine, Lisinopril, Amiloride
- Where
- 14 sites in United Kingdom
- Volunteers
- 940 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Contrast-induced Nephropathy
Role of Amlodipine in Reduction of CIN
The aim is to assess the benefit of low dose oral amlodipine in renal protection from contrast induced nephropathy in diabetic patients in intensive care unit
- Trial name
- NCT07291375
- Testing
- Calcium channel blocker, Hydration
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Minia University
Hypertension
A Clinical Trial to Evaluate the Safety and Pharmacokinetics of AJU-C52L in Healthy Volunteers
To evaluate the safety and pharmacokinetic characteristics of AJU-C52L in healthy adults
- Trial name
- NCT05077475
- Testing
- C52R1H Tab. and C52R2 Tab., AJU-C52L
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- AJU Pharm Co., Ltd.
Thalassemia Major
Amlodipine Use in the Prevention and Treatment of Iron Overload in Patients With Thalassemia Major
This study aims to investigate the use of amlodipine, a drug that blocks the uptake of calcium into cells, in the prevention and treatment of iron overload in patients with thalassemia major.
- Trial name
- AnloThal (NCT01125254)
- Testing
- Amlodipine
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- University of Campinas, Brazil
Hypertension
Efficacy and Safety of CKD-828 to Stage 2 Hypertension
The aim of present study is to evaluate the efficacy and safety of two dose combination of S-Amlodipine/Telmisartan (2.5/40mg, 2.5/80mg and 5/80mg) compared with S-Amlodipine monotherapy (2.5mg and 5mg) in patients with Stage 2…
- Trial name
- NCT01634295
- Testing
- CKD-828 2.5/40mg, CKD-828 5/40mg, CKD-828 5/80mg
- Where
- South Korea
- Volunteers
- 103 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Sleep Apnea Syndrome, Hypertension
Effects of Metoprolol and Amlodipine on Cardiac Remodeling, Arrhythmias and Blood Pressure Variation in Hypertensive Patients With Sleep Apnea Syndrome
Obstructive sleep apnea (OSA) is a highly prevalent chronic sleep disorder that affects 3% to 7% in middle aged individuals and increases with age.
- Trial name
- NCT02408172
- Testing
- Amlodipine, metoprolol
- Where
- 2 sites in China, Hungary
- Volunteers
- 20 people
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Atorvastatin Antihypertensive Effect
Atorvastatin as an Antihypertensive Agent
This study is aimed to see the antihypertensive effect of statin (Atorvastatin) as certain animal models have shown that statins have the voltage-gated calcium channel blocking effect.
- Trial name
- NCT05679102
- Testing
- Amlodipine 5 MG Oral Tablet, Amlodipine 5 MG / Atorvastatin 10 MG Oral Tablet
- Where
- Saudi Arabia
- Volunteers
- 120 people
- Sponsor
- Himayat Ullah
Hypertension
Telmisartan Versus Amlodipine in Patients With Mild-to-Moderate Hypertension
The primary aim of the trial is the effect of telmisartan versus amlodipine in lowering ambulatory diastolic and/or systolic blood pressures in the last six hours of the dosing interval in patients with mild-to-moderate…
- Trial name
- NCT02177409
- Testing
- Telmisartan, Amlodipine
- Volunteers
- 431 people
- Sponsor
- Boehringer Ingelheim
Essential Hypertension
RAS Peptide Profiles in Patients With Arterial Hypertension
Randomized, open-label, parallel-group study conducted at a single center in Switzerland. Patients diagnosed with primary arterial hypertension requiring antihypertensive drug Treatment as well as patients after a 4 week wash out…
- Trial name
- NCT02449811
- Testing
- Perindopril, Olmesartan, Amlodipine
- Where
- Switzerland
- Volunteers
- 107 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Lower Urinary Tract Symptoms, Hypertension
Effect of Amlodipine Monotherapy or Combined With Terazosin on Lower Urinary Tract Symptoms and Hypertension
The aim of this study was to investigate the efficacy and safety of low dose amlodipine alone, or combined with low dose terazosin in male patients with both lower urinary tract symptoms and hypertension.
- Trial name
- NCT00693199
- Testing
- amlodipine, terazosin, amlodipine plus terazosin
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Anhui Medical University
Thalassemia
Amlodipine for Myocardial Iron in Thalassemia
Children with thalassemia may have high iron levels after receiving blood transfusions. These high iron levels can have damaging effects on the body, especially the heart.
- Trial name
- AMIT (NCT02065492)
- Testing
- Standard Chelation, Amlodipine
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Aga Khan University
Hypertension
Efficacy/Safety of Valsartan Plus Amlodipine and Amlodipine Alone in Patients With Hypertension
This study will evaluate the safety and efficacy of the fixed combination of valsartan/amlodipine in adult patients with mild to moderate hypertension
- Trial name
- NCT00413049
- Testing
- Valsartan/amlodipine 80/5 mg, Amlodipine 5 mg
- Where
- 12 sites in China
- Volunteers
- 698 people
- Sponsor
- Novartis
Hypertension
Efficacy and Safety of Valsartan/Amlodipine Combination in Hypertensive Patients Not Controlled With Valsartan Alone
This study will test the effectiveness and safety of a combination treatment in patients whose blood pressure is not controlled with a single medication
- Trial name
- NCT00170963
- Testing
- valsartan/amlodipine
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 1,018 people
- Sponsor
- Novartis
Healthy
Safety and Pharmacokinetics Study of Amlodipine 10mg and Candesartan 32mg
Clinical trial to evaluate the pharmacokinetic interactions and safety between single dose of amlodipine 10mg and candesartan 32mg and the combination dose amlodipine 10mg with candesartan 32mg in healthy male volunteers.
- Trial name
- NCT01926652
- Testing
- candesartan cilexetil 32mg, amlodipine 10mg
- Where
- South Korea
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Shin Poong Pharmaceutical Co. Ltd.
Aging
Pharmacokinetics of Clinical Probes and Characteristics of Endogenous Biomarker in Chinese Older Adults
The goal of this observational study aims to reveal the pharmacokinetics of clinical probes and characteristics of endogenous biomarkers for drug-metabolizing enzymes and transporters in Chinese older adults and old older adults…
- Trial name
- NCT05893849
- Testing
- Clinical probes
- Where
- China
- Volunteers
- 624 people
- Sponsor
- Peking University Third Hospital
Hypertension
Safety and Efficacy of Valsartan and Amlodipine Combined and Alone in Hypertensive Patients
This trial will compare valsartan and amlodipine combination therapies to valsartan and amlodipine monotherapy,and placebo for treating patients with hypertension
- Trial name
- NCT00409643
- Testing
- valsartan+amlodipine combination, valsartan, amlodipine
- Where
- 2 sites in United States, Germany
- Volunteers
- 1,259 people
- Sponsor
- Novartis
Resistant Arterial Hypertension
Clinical One-stage Controlled Study of reSistant Arterial Hypertension for the desiGning of a personAlized Approach to Therapy
This study was planned to assess the concentration of antihypertensive drugs in the blood plasma in patients with controlled and uncontrolled arterial hypertension.
- Trial name
- SAGA (NCT05899920)
- Testing
- Blood samples will be taken for pharmacokinetics and pharmacogenetics
- Where
- Russia
- Volunteers
- 190 people
- Sponsor
- Ryazan State Medical University
Uncontrolled Hypertension
Adrenal Artery Ablation for Uncontrolled Hypertension
The activation of the renin-angiotensin-aldosterone system (RAAS) plays a key role in uncontrolled hypertension or resistant hypertension.
- Trial name
- NCT03660397
- Testing
- Selective endovascular chemical ablation of adrenal gland, Traditional triple antihypertensive treatment
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Third Military Medical University
Hypertension
Bioavailability of 5 mg of Levamlodipine Maleate Tablets Versus 10 mg of Amlodipine Besylate Tablet in Healthy Subjects
This study are (1) to assess the relative bioavailability (BA) of a single oral dose of either 5 mg of Levamlodipine Maleate Tablets from CSPC or 10 mg of Amlodipine Besylate Tablet (NORVASC®) from Pfizer Inc.
- Trial name
- NCT03657550
- Testing
- Levamlodipine, Amlodipine, Amlodipine, Levamlodipine
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Conjupro Biotherapeutics, Inc.