Clinical trials: Amlodipine
Hypertension
An Open-label, Long-term Study of Telmisartan Plus Amlodipine Fixed-dose Combination
To assess the long term safety and efficacy of telmisartan plus amlodipine FDC in patients with essential hypertension who failed to control their BP with either monotherapy
- Trial name
- NCT00618774
- Testing
- telmisartan40/amlodipine5, telmisartan80/amlodipine5
- Where
- 7 sites in Japan
- Volunteers
- 259 people
- Sponsor
- Boehringer Ingelheim
Aortic Valve Insufficiency
Open Label RCT for Chronic Severe AR : Entresto vs. CCB/ARB
The purpose of this study is to assess the efficacy of sacubitril-valsartan compared to the combination of ARB/CCB on left ventricular remodeling in patients with chronic aortic valve regurgitation.
- Trial name
- REVERSE-AR (NCT05212597)
- Testing
- Sacubitril-valsartan, Amlodipine-losartan
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Diabetic Nephropathy
Nephropathy In Type 2 Diabetes and Cardio-renal Events
The NID-2 study, a multicentric study (21 centres enrolled), was planned in two phases: Phase 1(observational study, completed in September 2005): after the identification of a type-2 diabetic population with typical Diabetic…
- Trial name
- NID-2 (NCT00535925)
- Testing
- SoC therapy, irbesartan, ramipril
- Where
- Italy
- Volunteers
- 850 people
- Sponsor
- University of Campania Luigi Vanvitelli
Atrial Fibrillation
Atrial Substrate Modification With Aggressive Blood Pressure Lowering to Prevent AF
Atrial fibrillation (AF) is a very common arrhythmia causing many symptoms resulting in numerous hospitalizations. Catheter ablation is a technique that has evolved significantly to improve symptomatic recurrences, but does not…
- Trial name
- SMAC AF (NCT00438113)
- Testing
- Aggressive Blood Pressure control
- Where
- Canada
- Volunteers
- 184 people
- Sponsor
- Nova Scotia Health Authority
Dyslipidemias, Hypertension
To Evaluate the Pharmacokinetics and the Safety of ID14009 Compared to Coadministration of ID1805 With ID1803 in Healthy Adult Volunteers
To evaluate the pharmacokinetics and the safety of ID14009 compared to coadministration of ID1805 with ID1803 in healthy adult volunteers.
- Trial name
- NCT05259020
- Testing
- ID140009, ID1803+ID1805
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IlDong Pharmaceutical Co Ltd
Hypertension, Abdominal Aortic Aneurysm
Study on Anti-inflammatory Effect of Anti-hypertensive Treatment in Patients With Small AAA's and Mild Hypertension
Inflammation of the blood vessel plays an important role in the development and growth of a dilated abdominal aorta. An elevated blood pressure leads to an increase in inflammation, therefore blood pressure lowering is an…
- Trial name
- PISA (NCT01425242)
- Testing
- Aliskiren, Amlodipine
- Where
- Netherlands
- Volunteers
- 3 people
- Sponsor
- Amsterdam UMC, location VUmc
Hypertension
Anti Inflammatory Treatment of Hypertension
To investigate the anti-inflammatory effect of amlodipine and levamlodipine in the treatment of hypertension
- Trial name
- NCT04740840
- Testing
- Levamlodipine, Amlodipine
- Volunteers
- 200 people
- Sponsor
- Affiliated Hospital of North Sichuan Medical College
HIV/AIDS, Hypertension
Integration of Hypertension Management in HIV Care in Uganda
Effective, cost-effective, scalable, sustainable, and equitable implementation strategies to improve care for people living with HIV and co-morbid hypertension in sub-Saharan Africa are urgently needed.
- Trial name
- PULESAUganda (NCT05609513)
- Testing
- HTN-BASIC, HTN-PLUS
- Where
- 16 sites in Uganda
- Volunteers
- 87,421 people
- Sponsor
- Infectious Diseases Research Collaboration, Uganda
Hypertension, Dyslipidemias
To Evaluate the Pharmacokinetic/Pharmacodynamic Interactions and Safety Between ID1801 and ID1803 in Healthy Male Adults
This study is designated to evaluate the pharmacokinetic interactions of valsartan, amlodipine besylate, rosuvastatin, and ezetimibe in healthy male volunteers.
- Trial name
- NCT04185090
- Testing
- ID1803, ID1801, ID1803+ID1801
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- IlDong Pharmaceutical Co Ltd
Hypertension
Treatment of Resistant Hypertension by Prevention of T-Cell Co-Stimulation
The purpose of this study is to test whether abatacept, a drug approved by the Food and Drug Administration to treat rheumatoid arthritis, may help blood pressure medications to work better.
- Trial name
- NCT02232880
- Testing
- Abatacept
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Vanderbilt University Medical Center
Healthy Volunteers
Pharmacokinetics of Irbesartan/Amlodipine FDC and Co-administration of Irbesartan and Amlodipine in Healthy Volunteers
The purpose of this study is to compare pharmacokinetics and safety of Irbesartan and Amlodipine Fixed Dose Combination and coadministration of mono compounds in healthy adult volunteers
- Trial name
- NCT05663073
- Testing
- Irbesartan/Amlodipine FDC, Irbesartan, Amlodipine
- Where
- South Korea
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Handok Inc.
Hypertension
Effect of Nocturnal Administration of Anti-hypertensive Medications in NoN-dippers
The purpose of this study is to determine the effect of nocturnal administration of Anti-hypertensive medications in Non-dippers. Efficacy variables. 1. ECHO 2. 24hr. horter 3. IMT 4. BUN/crea, urine analysis (microalbulinuria 5.
- Trial name
- NCT01091753
- Testing
- Valsaltan, amlodipine
- Where
- South Korea
- Volunteers
- 28 people
- Sponsor
- Yonsei University
Hypertension
A Study to Evaluate Efficacy and Safety of HCP1401 for Stage 2 Hypertension Patients Not Controlled by HCP0605
A phase 3 study to evaluate efficacy and safety of HCP1401
- Trial name
- NCT02916602
- Testing
- HCP1401, HCP0605
- Where
- South Korea
- Volunteers
- 340 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Hypertension
Efficacy/Safety of Valsartan Plus Amlodipine and Valsartan Alone in Patients With Hypertension
This study evaluated the safety and efficacy of the fixed combination of valsartan/amlodipine in adult patients with mild to moderate hypertension.
- Trial name
- NCT00413413
- Testing
- Valsartan/amlodipine 80/5 mg, Valsartan 80 mg, Valsartan 160 mg
- Where
- 19 sites in China
- Volunteers
- 1,134 people
- Sponsor
- Novartis Pharmaceuticals
Hypertension
Feasibility Study of a Novel mHealth Application to Enable Community Health Workers to Manage
This is a single group study assessing the feasibility of hypertension management by community health workers (CHWs) equipped with a mobile clinical decision support (CDS) application and working with remote physician supervision.
- Trial name
- NCT05479097
- Testing
- Anti-Hypertensive
- Where
- Guatemala
- Volunteers
- 32 people
- Sponsor
- University of Wisconsin, Madison
Healthy Volunteers
Drug-drug-interaction Study of Candesartan, Amlodipine and Atorvastatin
Study to determine the potential pharmacokinetic interaction of candesartan cilexetil, atorvastatin as atorvastatin calcium trihydrate and amlodipine as amlodipine besilate at steady state after a multiple oral administration and…
- Trial name
- NCT04245046
- Testing
- Candesartan, Amlodipine, Atorvastatin
- Where
- Jordan
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Midas Pharma GmbH
Essential Hypertension
Series of N-of-1 Crossover Trials of Antihypertensive Therapy in Adolescents With Essential Hypertension
Children are increasingly being diagnosed with essential hypertension and the absence of comparative effectiveness research in antihypertensive therapies has contributed to considerable differences in prescribing practices among…
- Trial name
- NCT02412761
- Testing
- Lisinopril, Amlodipine, Hydrochlorothiazide
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- The University of Texas Health Science Center, Houston
Hypertension
Lowering Blood Pressure in Primary Care in Vienna
The aim of this prospective, randomised, open-label, multicentre clinical trial is to enhance blood pressure control in primary care by introducing a standardised and simplified titration regime with single pill combinations…
- Trial name
- Low BP Vienna (NCT02377661)
- Testing
- Olmesartan medoxomil, amlodipine, hydrochlorothiazide
- Where
- Austria
- Volunteers
- 229 people
- Sponsor
- Wilhelminenspital Vienna
Hypertension
Long Term Study Of Amlodipine 10mg With Hypertension For Whom Amlodipine 5mg Is Insufficient
To investigate the safety and efficacy of the long-term use of amlodipine 10 mg in subjects who will be able to enter a long-term study after completing the parent study "A double-blind comparative study between amlodipine 5 mg…
- Trial name
- NCT00443456
- Testing
- Amlodipine
- Where
- 9 sites in Japan
- Volunteers
- 134 people
- Sponsor
- Pfizer
Healthy
Amlodipine 10 mg Tablets Under Fed Conditions
The objective of this study is to compare the rate and extent of absorption of amlodipine from a test formulation of Amlodipine Besylate Tablets, 10 mg versus the reference Norvasc® 10 mg Tablets under fed conditions.
- Trial name
- NCT00841815
- Testing
- Amlodipine Besylate, Norvasc®
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Teva Pharmaceuticals USA