Clinical trials: Best Practice, completed
Back Pain
Determining the Impact of a New Physiotherapist Led Primary Care Model for Back Pain
This is a pilot cluster randomized controlled trial to determine the feasibility of a cluster randomized trial to evaluate the individual and health system impact of implementing a new physiotherapist-led primary care model for…
- Trial name
- NCT03320148
- Testing
- Physiotherapist-led primary care model for back pain, Usual care
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Queen's University
Autism Spectrum Disorder
Neuro Strengths-Based Approach to Autism
The Neuro-Strength-Based Approach to Autism (NSBAA) attempts to translate what research has discovered about the autistic brain into terms that autistics, and those involved with autistics, can understand.
- Trial name
- NSBAA (NCT05499910)
- Testing
- NSBAA
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Baio Enterprises
Diabetes Mellitus, Type 2
PROmoting Diabetes Education and Management Through Peer Support and Team Referral
A 3-step project is proposed. Step 1 will test which BPA time point(s) maximize referral rates to DSMES services in the real world clinic setting (Aim 1).
- Trial name
- PROMPT (NCT05587348)
- Testing
- Best Practice Advisory, Peer Support, Usual Care
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- University of North Carolina, Chapel Hill
ANEMIA
Anemia Management in Chronic Kidney Disease Not on Dialysis Patients After the European Renal Best Practice (ERBP) Working Group Recommendations
The purpose of this study is to evaluate the impact of the last recommendations of the European Anemia Working Group ERBP in the anemia management in the achievement of the therapeutic goal of Hb 11-12 g/dL.
- Trial name
- ACERCA (NCT01903148)
- Where
- 29 sites in Spain
- Volunteers
- 455 people
- Sponsor
- Fundación Senefro
Stroke
Predicting Ipsilesional Motor Deficits in Stroke With Dynamic Dominance Model
This study will test the hypothesis that the combination of low-moderate to severe motor deficits in the paretic arm and persistent motor deficits in the less-impaired arm limits functional independence in chronic stroke…
- Trial name
- NCT03634397
- Testing
- Less-Impaired Arm Training, Contralesional Arm Comparison
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- Robert L. Sainburg
Anxiety, No Evidence of Disease
Video-Based Intervention in Reducing Anxiety in Patients Undergoing Lung Cancer Screening
This pilot trial studies a video-based intervention in reducing anxiety in patients undergoing lung cancer screening. Giving a video-based intervention to patients prior to lung cancer screening may reduce anxiety and improve the…
- Conditions
- Anxiety, No Evidence of Disease, Lung Carcinoma
- Trial name
- NCT02288416
- Testing
- educational intervention, questionnaire administration, quality-of-life assessment
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Diabetes Mellitus, Quality of Health Care
Randomised Controlled Trial of Structured Personal Care of Type 2 Diabetes Mellitus
The aims of a concluding 14-year follow-up study are: To investigate what long-term effect the project model for structured, personalized diabetes care has on 1) the patients' mortality and development of diabetic complications…
- Conditions
- Diabetes Mellitus, Quality of Health Care, Health Services Research
- Trial name
- DCGP (NCT01074762)
- Testing
- Structured personal care
- Where
- Denmark
- Volunteers
- 1,470 people, healthy volunteers welcome
- Sponsor
- Research Unit Of General Practice, Copenhagen
Autism Spectrum Disorder
A Trial of Project ImPACT in Early Intervention
Our pilot study will address a number of pressing questions, including: Can community clinicians successfully coach parents of children with ASD in evidence-based practice to achieve positive outcomes for their children and…
- Trial name
- NCT04729127
- Testing
- Project ImPACT
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- University of Pennsylvania
Nursing Caries
The Effect of Standardised Patient Simulation in Nursing Education
With the coronavirus outbreak, the experience of nursing students with personal protective equipment is one of the issues of interest.
- Trial name
- NCT06566924
- Testing
- Control, Training Group for Standardised Patient Simulation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Beykent
Hypertension
An Observational Study to Evaluate the Efficacy of Lodoz in a Population of Hypertensive Patients
This is an observational, prospective, non-interventional, non-randomised, open label multicentric study planned to be conducted in 1000 subjects with mild to moderate primary hypertension in approximately 20 centres in Thailand.
- Trial name
- Lodoz OS (NCT01080742)
- Testing
- Lodoz (Combination of bisoprolol and hydrochlorothiazide)
- Where
- Thailand
- Volunteers
- 1,007 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Physical Activity
Moderate Aerobic Activity Through Yoga
The 2018 Physical Activity Guidelines for Americans (PAGA) recommend 150 minutes of moderate intensity activity for adult (18 years and older) Americans to promote health.
- Trial name
- MAT (NCT05184673)
- Testing
- Behavioral and environmental
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Neuromuscular Diseases
Evaluation of an On-Demand Humidifier on Neuromuscular Patients Requiring Mechanical Ventilation
Monocenter study to determine and evaluate the optimal amount of humidification doses delivered by the On-Demand humidification system in neuromuscular patients requiring home mechanical ventilation.
- Trial name
- NCT03289715
- Testing
- On Demand Humidification system Mark 2
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Philips Clinical & Medical Affairs Global
Cerebral Hypoxia, Severe Traumatic Brain Injury
Prioritization of Cerebral Deoxygenation in Severe Traumatic Brain Injury and Mortality Benefit.
Severe traumatic brain injury with a decrease in cerebral oximetry is associated with multiple impaired systemic microcirculations, more morbidities, and a higher mortality rate.
- Trial name
- NCT06306950
- Testing
- Near infrared spectroscopy neuromonitor to prevent cerebral desaturation
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Chemotherapy-Induced Peripheral Neuropathy, Malignant Solid Neoplasm
Evaluating a Mobile Health Application Intervention for Caregiver Instruction in Manual Therapy for Chemotherapy-Induced Peripheral Neuropathy
This clinical trial assesses the impact of a family caregiver-delivered massage technique for use in cancer survivors with chemotherapy-induced peripheral neuropathy (CIPN).
- Conditions
- Chemotherapy-Induced Peripheral Neuropathy, Malignant Solid Neoplasm, Hematopoietic and Lymphatic System Neoplasm
- Trial name
- NCT06945380
- Testing
- Best Practice, Comparator Program, Best Practice, Usual Care, Internet-Based Intervention
- Where
- United States
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Pancreatic Cancer
Dose-escalation, and Safety Study of LDE225 and Gemcitabine in Locally Advanced or Metastatic Pancreatic Cancer Patients
This phase Ib study includes two phases: dose escalation phase and safety expansion phase. During the dose escalation phase, successive cohorts of eligible patients (minimum 3 and maximum 6 evaluable patients per cohort) will…
- Trial name
- NCT01487785
- Testing
- LDE225+gemcitabine
- Where
- 5 sites in United States, Spain and 1 more
- Volunteers
- 18 people
- Sponsor
- Novartis Pharmaceuticals
Obesity
WOOP VA: Promoting Weight Management in Primary Care
Approximately 40% of Veterans have obesity and are at increased risk for cardiometabolic disease. Intensive lifestyle-based weight management programs can lead to clinically significant ( 5%) weight loss.
- Trial name
- WOOP VA (NCT05014984)
- Testing
- mental contrasting with implementation intentions, telephone-delivered, telehealth-delivered, and or in-person MOVE! or TeleMOVE!, Information About Diet, Physical Activity, and Weight Management (Baseline Visit - 10 minutes): All
- Where
- United States
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Trauma, Psychological, Social Skills
The Impact Integrated Data System for Quality and Outcomes Tracking of Prevention Programs
There has been substantial progress in developing evidence-based prevention programs (EBPPs) for preventing risky behaviors and promoting positive outcomes for youth.
- Conditions
- Trauma, Psychological, Social Skills, Family Dysfunctional
- Trial name
- Impact (NCT03622138)
- Testing
- Impact
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- 3-C Institute for Social Development
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Perioperative Care in the Cancer Patient -1, ARCA-1 Study
This study investigates the association of blood transfusions given around the time of surgery (perioperative) with complications after surgery (postoperative), cancer progression, and mortality after major oncologic non-cardiac…
- Trial name
- NCT04491409
- Testing
- Best Practice, Medical Chart Review
- Where
- United States
- Volunteers
- 229 people
- Sponsor
- M.D. Anderson Cancer Center
Care Giver, Recurrent Malignant Neoplasm
PCRC-Supported Legacy Intervention in Pediatric Palliative Care
This trial studies how well a web-based legacy intervention works in improving the quality of life in caregivers and younger patients with cancer that has come back (recurrent) or does not respond to treatment (refractory).
- Conditions
- Care Giver, Recurrent Malignant Neoplasm, Refractory Malignant Neoplasm
- Trial name
- NCT04059393
- Testing
- Internet-Based Intervention, Best Practice, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Vanderbilt-Ingram Cancer Center
Aortic Stenosis
Construction and Application Plan of Home Cardiac Rehabilitation for Patients Undergoing TAVR
Cardiac rehabilitation is a long-term process, but patients have poor compliance with cardiac rehabilitation. The theory of behavior change rotation aims to comprehensively intervene from three aspects: ability, opportunity, and…
- Trial name
- NCT06418555
- Testing
- A home rehabilitation program centered on exercise
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine