Clinical trials: Blood sampling, completed
Hemodialysis
Influence of Hemodialysis on Endothel-Depending Dilatation of Peripheral Arteries
An impairment of nitric oxide (NO) bioavailability is associated with endothelial dysfunction and may contribute to the excessive incidence of cardiovascular complication in chronic haemodialysis (HD) patients.
- Trial name
- NCT00764192
- Testing
- blood sample, Flow-mediated dilation (FMD) before and after a single HD
- Where
- Germany
- Volunteers
- 14 people
- Sponsor
- RWTH Aachen University
Diabetes Mellitus, Type 2
Insulin Resistance as Primary Pathogenesis in Newly Diagnosed, Drug naïve Type 2 Diabetes Patients in Korea
The purpose of this study is investigating the clinical characteristics of newly diagnosed, drug naïve type 2 diabetic patients according to insulin secretion and insulin resistance.
- Trial name
- SURPRISE (NCT01154244)
- Testing
- HOMA-IR
- Where
- 2 sites in South Korea
- Volunteers
- 1,439 people
- Sponsor
- GlaxoSmithKline
Endometriosis, Cell Free DNA
Cell Free DNA Quantification in Patients With Endometriosis Followed Witd Medical Assistance to Procreation
Endometriosis is a common benign disease in premenopausal women and causes chronic pelvic pain and infertility. This infertility may be due to pelvic adhesions and surgery but also because of poor oocyte quality.
- Trial name
- ENDO-FIV (NCT05815134)
- Testing
- blood sample
- Where
- France
- Volunteers
- 114 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Metabolic Syndrome, Hypertriglyceridemia
Nutritional Transitions to More Plant Proteins and Less Animal Proteins: Understanding the Induced Metabolic Reorientations and Searching for Their Biomarkers (ProVegOmics)
The dietary shift from animal to plant protein sources is one of the key aspects of the nutritional transition towards more sustainable food system and diets.
- Conditions
- Metabolic Syndrome, Hypertriglyceridemia, Fasting Blood Sugar Above Normal, Lower Than Standard HDL-cholesterol Level
- Trial name
- ProVegOmics (NCT04236518)
- Testing
- Diets with either predominantly animal protein sources., Diets with predominantly plant protein sources
- Where
- France
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Hematologic Diseases, Oncology Problem
Clinical Validation of a Dried Blood Spot Method for Analysis of Immunosuppressives and Antifungals in Pediatrics
This is a clincial validation study of a dried blood spot (DBS) method for the analysis of immunosuppressive and antifungal agents currently subject of therapeutic drug monitoring (TDM) in a pediatric population.
- Conditions
- Hematologic Diseases, Oncology Problem, Kidney Diseases, Transplantation Infection
- Trial name
- PROTECT (NCT02329808)
- Testing
- blood drawing
- Where
- Netherlands
- Volunteers
- 93 people
- Sponsor
- Radboud University Medical Center
Obesity, Bariatric Surgery
Safety Profile of IntRAvenous Lidocaine Use in Coelioscopic Bariatric Surgery
Intravenous lidocaine is efficient for management of post operative pain in abdominal surgery. As previously published in literature the investigators use it during bariatric surgery.
- Trial name
- SPIRAL (NCT02525016)
- Testing
- Blood sampling, Lidocaine
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hospices Civils de Lyon
Pain Management, Nonpharmalogical Pain Management
Impact of Buzzy and Finger Puppets on Children's Pain, Fear, and Anxiety During Venipuncture
This study evaluates the impact of the Buzzy device and finger puppet distraction on pain, fear, and anxiety in children aged 4-7 undergoing venipuncture in a pediatric emergency department.
- Conditions
- Pain Management, Nonpharmalogical Pain Management, Children Pain Management
- Trial name
- Pain Relief (NCT06849648)
- Testing
- The Buzzy Device, Finger Puppet
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Kutahya Health Sciences University
Diabetes Mellitus, Type 2, Insulin Resistance
Day-Night Rhythm in Human Skeletal Muscle
This study evaluates the existence of a day-night rhythm in skeletal muscle energy metabolism in healthy lean subjects. Subjects will stay at the research facility for 44 hours with a standardized living protocol during which…
- Trial name
- NCT02261168
- Testing
- Standardized living protocol
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Anti-Hepatitis A Antibody Levels in Heathy Subjects
Anti-Hepatitis A Virus, Pharmacokinetics, and Safety of Immune Globulin (Human)
This was a single center, open-label, single-arm study in which approximately 28 Hepatitis A virus (HAV)-seronegative healthy subjects were enrolled.
- Trial name
- GamaSTAN (NCT03351933)
- Testing
- Immune Globulin (Human)
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Grifols Therapeutics LLC
Hematologic Diseases, Stem Cell Transplantation
Lipopolysaccharide Metabolism and Identification of Potential Biomarkers Predictive of Graft-versus-host Disease After Allogeneic Stem Cell Transplantation
This study is designed to assess the hypothesis that the lipopolysaccharide (LPS) activity index can be quantified early after transplantation, as well as the the PhosphoLipid Transfer Protein (PLTP) activity and these both…
- Trial name
- MetAlloLip (NCT03918343)
- Testing
- Blood sample
- Where
- 2 sites in France
- Volunteers
- 95 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Increased Nuchal Translucency in the First Trimester of Pregnancy
Metatranscriptomic Next Generation Sequencing in First Trimester Trophoblast With Increased Fetal Nuchal Translucency (METAHCN)
The study is based on the hypothesis that increased nuchal translucency may be associated with a materno fetal infection and that the pathogen responsible for this infection could be identify with metatranscriptomic…
- Trial name
- METAHCN (NCT05388968)
- Testing
- Metatranscriptomic, Specific microbiologic diagnosis
- Where
- France
- Volunteers
- 78 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Liver Fibrosis, Alpha-1 Antitrypsin Deficiency
Liver Fibrosis in Alpha-1 Antitrypsin Deficiency (Liver AATD)
We hypothesize that individuals with Alpha-1 Antitrypsin (AAT) deficiency have ongoing liver injury which is not detected by the usual blood tests used to look at liver function.
- Conditions
- Liver Fibrosis, Alpha-1 Antitrypsin Deficiency, AAT Deficiency, AATD
- Trial name
- NCT01810458
- Testing
- Abdominal ultrasound, History and physical, Intravenous catheter
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- University of Florida
Non Small Cell Lung Cancer
Study to Assess the Effect of AZD9291 on the Blood Levels of Rosuvastatin, in Patients With EGFRm+ Non-small Cell Lung Cancer
This is a Phase I, open-label, 2-part study in patients with a confirmed diagnosis of epidermal growth factor receptor (EGFR) mutation positive (EGFRm+) non-small cell lung cancer (NSCLC), who have progressed following prior…
- Trial name
- NCT02317016
- Testing
- Pharmacokinetic sampling - AZD9291, AZD9291 tablet dosing, Rosuvastatin
- Where
- 13 sites in United States, France and 2 more
- Volunteers
- 44 people
- Sponsor
- AstraZeneca
Colorectal Cancer
Development of a Serum Test for Colorectal Cancer Screening (COLODIAG préclinique)
Colorectal cancer (CRC) is a major public health problem, with 44,872 new cases per year in France (3rd most common cancer), and 17,684 deaths (2nd cause of death from cancer).
- Trial name
- COLODIAG pre (NCT04659018)
- Testing
- blood collection
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Localized Non-Resectable Adult Hepatocellular Carcinoma
Chemoembolization of Non-resectable Non-metastatic Hepatocellular Carcinoma Using Embolization Microspheres
Chemoembolization is a recognized treatment strategy for hepatocellular carcinoma (HCC) classical chemoembolization consists in injecting an emulsion of an anticancer agent in Lipiodol® via the hepatic artery doxorubicin, an…
- Trial name
- IDASPHERE (NCT02870010)
- Testing
- blood samples (5 ml) will be taken, Chemoembolization
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Carcinoma, Carcinoma, Renal Cell
Biomarkers for Angiogenesis in Renal Cell Carcinoma and Neuro-endocrine Tumours.
The primary objective of this study is to analyse the concentration dopamine and serotonin in thrombocytes of patients with renal cell carcinoma and neuro-endocrine tumours compared to the concentrations of these catecholamines…
- Conditions
- Carcinoma, Carcinoma, Renal Cell, Neuroendocrine Tumors, Carcinoid Tumor
- Trial name
- BANN (NCT01398306)
- Testing
- Blood sampling by vena punction.
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- University Medical Center Groningen
Interstitial Lung Diseases
Nanoparticles Analysis in Lung and Bronchi During Various Pulmonary Interstitial Diseases and Relationships With Their Aetiology
Nanoparticles (NP) are particles whose length, width and height are less than 100 nanometres. Over the past decade, industrial applications of NP have increased dramatically.
- Trial name
- NANOPI (NCT02549248)
- Testing
- BAL, BW, EAC
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Psoriasis, Anti Mullerian Hormone
Ovarian Reserve in Patients With Psoriasis
Psoriasis is a common autoimmune disease. It affects women of all ages including reproductive years. Autoimmune diseases including psoriasis are linked to premature ovarian reserve.
- Conditions
- Psoriasis, Anti Mullerian Hormone, Ovarian Reserve
- Trial name
- NCT03492632
- Testing
- Hormone panel
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Exostoses, Multiple Hereditary
Height, Ulnar Length and Forearm Function in Multiple Hereditary Exostoses
the purpose of the present registry is to describe the epidemiology of forearm deformities in patients with Hereditary Multiple Exostoses and to identify, independent predictors of severity of the disease and potential…
- Trial name
- NCT05914298
- Testing
- blood and buccal swab genetic test, PUL, Range of motion
- Where
- Italy
- Volunteers
- 408 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Head and Neck Squamous Cell Carcinoma
Chemoprevention of Head and Neck Squamous Cell Carcinoma (HNSCC) With Valproic Acid
This study evaluates the addition of valproic acid as a chemopreventive drug in head and neck squamous cell carcinoma (HNSCC) patients that do not have signs of recurrence or residual disease.
- Trial name
- GAMA (NCT02608736)
- Testing
- Valproic Acid
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- Barretos Cancer Hospital
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