Clinical trials: Bupivacaine
Non-small Cell Lung Cancer
The Effect of Combined General/Regional Anesthesia on Cancer Recurrence in Patients Having Lung Cancer Resections
The primary hypothesis is that disease-free survival is improved in patients undergoing resection for tumor thought to be stage I-III primary non-small cell lung cancer in patients with combined general-epidural anesthesia \&…
- Trial name
- NCT02840227
- Testing
- General anesthesia with opioid analgesia, Combined general/epidural anesthesia
- Where
- China
- Sponsor
- The Cleveland Clinic
Opioid Use, Postoperative Pain
Analgesic Effects of Intrathecal Morphine and Bilateral Erector Spina Plane Block in Elective Cesarean Section
Cesarean section cause severe pain due to surgical incision, abdominal wall retraction and visceral organ movements. Cesarean section can be performed with general anesthesia, spinal anesthesia, epidural anesthesia and combined…
- Trial name
- NCT05698927
- Testing
- Erector Spinae Plane Block (bilaterally, via 20ml % 0.25 bupivacain) and Intrathecal Morphine (100 mcg)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Marmara University
Breast Cancer
Subpectoral Plexus Block With Multi-level TPVB for Surgical Anesthesia During Primary Breast Cancer Surgery
The objective of this study is to compare two different doses of local anesthetics (10ml vs 20ml of 0.25% levobupivacaine) for subpectoral plexus block (SPPB) in addition to ultrasound guided multi-level of thoracic paravertebral…
- Trial name
- NCT04933266
- Testing
- Subpectoral plexus block (low dose), Subpectoral plexus block (High dose)
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Chinese University of Hong Kong
Pain Control
Efficacy of TAP Block in Cesarean Section Patients
TAP Block done with 2 different concentrations of bupivacaine and placebo
- Trial name
- NCT03493828
- Testing
- TAP block using Bupivacaine 0.5%, TAP block using Bupivacaine 0.25%, TAP block using Normal Saline
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- New York Presbyterian Brooklyn Methodist Hospital
Morbid Obesity, High BMI
Efficacy Of Quadratus Lumborum II Block For Laparoscopic Sleeve Gastrectomy
The QL 2 block is a novel fascial plane block recently described by Blanco and colleagues in which local anesthetic is deposited adjacent to the antero-lateral aspect of the quadratus lumborum muscle.
- Trial name
- NCT04073056
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hypotension, Spinal Anesthesia
Prophylactic Ondansetron for Preventing Spinal Anesthesia-Induced Hypotension in Elective Cesarean Section
Spinal anesthesia is the preferred technique for elective cesarean section, but it frequently causes maternal hypotension due to sympathetic blockade and the Bezold-Jarisch reflex, which can threaten both mother and baby.
- Conditions
- Hypotension, Spinal Anesthesia, Cesarean Section
- Trial name
- NCT07886151
- Testing
- Ondansetron
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Osteosarcoma, Analgesia
Efficacy of Epidural Analgesia in Lower Extremity Osteosarcoma
In this study, the investigators aim to reduce complications in orthopedic malignancy surgeries and to increase the quality of life of patients who will be operated on.
- Trial name
- NCT04945512
- Testing
- Epidural Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Istanbul University
Postoperative Pain
Comparison of Bilateral Thoracic Paravertebral Block to Thoracic Epidural Analgesia for Post Operative Analgesia in Patients Undergoing Abdominal Surgery
Pain following abdominal surgery is managed with the use of thoracic epidural analgesia (TEA) where the epidural is inserted in the spine at the level of scapula The risks due to TEA include difficulty with insertion, failure in…
- Trial name
- NCT01735851
- Testing
- Thoracic epidural analgesia, Bilateral Paravertebral block
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Anesthesia, Spinal, Elderly
Influence Of Low Dose Intrathecal Naloxone On Bupivacaine - Fentanyl Spinal Anaesthesia For Lower Limb Orthopedic Surgery In Elderly Patients
Fentanyl is a safer alternative than morphine in the management of postoperative pain in elderly. However, pruritus, nausea and vomiting are unwanted side effects of intrathecal fentanyl administration, that can decrease patient…
- Trial name
- NCT04673812
- Testing
- Bupivacaine-fentanyl
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Kasr El Aini Hospital
Opioid Consumption, Numerical Rating Scale
Comparison of Bi-Level Erector Spinae Plane Block (ESPB) and Modified Thoraco Abdominal Plane Block (M-TAPA)
Laparoscopy is a surgical technique used for basic diagnosis and treatment. The advantages of laparoscopic techniques compared to open surgery have been demonstrated by studies.
- Conditions
- Opioid Consumption, Numerical Rating Scale, Demographic Data
- Trial name
- NCT06742177
- Testing
- Group Bi-level ESPB, Group M-TAPA block
- Volunteers
- 50 people
- Sponsor
- Ankara Etlik City Hospital
Laparoscopic Cholecystectomy
Bilateral External Oblique İntercostal (EOI) Plane Block in Patients Undergoing Laparoscopic Cholecystectomy.
This study will define the postoperative analgesic effect of ultrasound-guided bilateral External Oblique İntercostal (EOI) Plane Block and compare the control group in patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT05536557
- Testing
- Bilateral External Oblique İntercostal (EOI) Plane Block, Standard perioperative and postoperative multimodal analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Karaman Training and Research Hospital
Post Operative Pain
A Comparison Between The Efficacy of Modified Thoracoabdominal Plane Block Via Perichondral Approach (M-TAPA) And External Oblique Intercostal Plane Block (EOIPB) in Patients Undergoing Laparoscopic Cholecystectomy Surgeries (LC)
Because laparoscopic procedures have a number of benefits over open procedures, they have completely changed the surgical industry.(1) Laparoscopic cholecystectomy (LC) is a minimally invasive technique that usually yields less…
- Trial name
- NCT06810206
- Testing
- Bilateral Ultrasound Guidance M-TAPA, Bilateral Ultrasound Guidance EOIPB
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
Facet Syndrome of Lumbar Spine
Fluoroscopy Guided Lumbar Facet Joint Injection Versus Ultrasound Guided Injection in Patients With Low Back Pain Due to Facet Syndrome
The aim of this study is to compare the efficacy of fluoroscopy guided lumbar facet joint injection versus ultrasound guided injection in patients with low back pain due to facet syndrome.
- Trial name
- NCT03770585
- Testing
- Fluoroscopy guided Facet joint injection, Ultrsound guided Facet joint injection
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Anesthesia; Adverse Effect, Spinal and Epidural
Comparative Study Between Continuous Epidural Anesthesia And Continuous Spinal Anesthesia Using Wiley™ Spinal Catheter
Geriatric patients have a significantly higher incidence of morbidity and morality during surgery compared with younger age group.
- Trial name
- NCT01845389
- Testing
- Epidural (B. Braun), Spinal (Wiley Spinal Catheter)
- Where
- 2 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Theodor Bilharz Research Institute
Total Knee Arthroplasty
Bupivacaine Liposome Suspension Versus a Concentrated Multi Drug Periarticular Injection
Despite a robust multimodal pain management regimen, patients undergoing total knee arthroplasty (TKA) continue to report low satisfaction with postoperative pain management.
- Trial name
- NCT02299349
- Testing
- bupivacaine liposome suspension, concentrated multi drug Ketorlac, Morphine PF, Epinephrine, Ropivicaine, 0.9% NaCL
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Pain Due to Certain Specified Procedures
Single Injection Infromedial Peribulbar Injection in Lacrimal Duct
infromedial injection of 3 ml local anesthetic drugs and assessing the pain during lacrimal duct intubation and probability of false tracking
- Trial name
- NCT04859049
- Testing
- infromedial single injection, medial canthus injection
- Where
- 2 sites in Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Research Institute of Ophthalmology, Egypt
Post-Craniotomy Headache
ERAS Approach for Post-Craniotomy Headache and Psychological Recovery
This randomized multicenter study involves patients undergoing intracranial surgeries (Population) to evaluate whether a perioperative analgesia protocol including scalp block (SB) with dexmedetomidine (DEX) infusion…
- Trial name
- NCT07510217
- Testing
- Scalp block with 0.5% plain Marcaine, dexmedetomidine, Intraoperative Analgesia
- Where
- Egypt
- Volunteers
- 139 people
- Sponsor
- Tanta University
Erector Spina Plan Block
The Effect of bılateral Erector spına Plan Block on postoperatıve paın ın spınal Surgery
Patients undergoing lumbar spinal stabilization surgery may experience severe postoperative pain lasting at least three days. Analgesia after lumbar stabilization surgery is beneficial for early recovery and is therefore…
- Trial name
- ESPB (NCT07537647)
- Testing
- UNDER ULTRASOUND GUİDANCE ESPB BLOCK, PROCEDURE/SURGERY: ERECTOR SPİNAE (ESP) BLOCK WİTH BUPİVACAİNE
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Arteriovenous Fistula, Brachial Plexus Block
Supraclavicular Versus Axillary Block for Arteriovenous (AV) Fistula Creation
This study compares the analgesic efficacy of supraclavicular brachial plexus nerve block to axillary nerve block techniques in adults undergoing AV fistula creation.
- Conditions
- Arteriovenous Fistula, Brachial Plexus Block, Clinical Efficacy
- Trial name
- CUGSCAB (NCT05809258)
- Testing
- Supraclavicular block, Axillary block
- Where
- Oman
- Volunteers
- 120 people
- Sponsor
- Sultan Qaboos University
Rib Fractures, Rib Fracture Multiple
US-guided SAPB for Rib Fractures in the ED
The purpose of this randomized controlled study is to determine whether the serratus anterior plane block reduces pain more than the usual treatment for rib fractures in the same amount of time.
- Trial name
- NCT03619785
- Testing
- Bupivacaine, Fentanyl, morphine, hydromorphone, hydrocodone, acetaminophen, ketorolac, gabapentin, ketamine, ibuprofen
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Andrew A Herring
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