Clinical trials: Bupivacaine
Orthopedic Disorder, Shoulder Pain
Peng Block or Suprascapular Nerve Block for Postoperative Analgesia in Shoulder Artroscopy ?
Arthroscopic shoulder surgery, which has been frequently applied in recent years, provides long-term positive clinical results and increases the quality of life after surgery, while it can cause severe pain in the early…
- Conditions
- Orthopedic Disorder, Shoulder Pain, Surgery, Analgesia
- Trial name
- NCT05666076
- Testing
- Pericapsular nerve block, Suprascapular nerve block, Bupivacaine Hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Abdominal Cancer, Abdominal Pain
Safety and Efficacy of Intrathecally Administered Magnesium Sulfate
Magnesium sulfate safety profile has been documented by histopathological analysis in experimental studies. magnesium sulfate added to local anesthetics decrease postoperative opioid requirements.
- Trial name
- NCT03459417
- Testing
- intrathecal morphine+LA, intrathecal morphine+LA+ Mg sulp. 50, intrathecal morphine+LA+ Mg sulp. 100
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- South Egypt Cancer Institute
Post Operative Pain, Spinal Fusion
Postoperative Pain Control in AIS Using Liposomal Bupivacaine vs. 0.25% Bupivacaine With Epinephrine
A randomized controlled trial (RCT) investigating whether the local anesthetic injection of liposomal bupivacaine during posterior spinal fusion (PSF) for AIS is more effective in reducing acute postoperative opioid consumption…
- Trial name
- NCT06471348
- Testing
- Bupivacaine liposome injectable suspension, Bupivacaine Hydrochloride and Epinephrine Injection
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Boston Children's Hospital
Headache Disorders, Primary, Pain Management
Paracervical Injection for Headache in the Emergency Department
Headache is one of the most common presenting complaints in the emergency department.1 By the time patients with benign headaches present for treatment in the ED, they often have exhausted non-invasive treatments, and physicians…
- Conditions
- Headache Disorders, Primary, Pain Management, Emergency Department
- Trial name
- NCT04109885
- Testing
- Paracervical injection, prochlorperazine and diphenhydramine.(Standard Treatment)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Christian Fromm, MD
Analgesia
Comparison of Meperidine and Sufentanil Added to 0.5% Hyperbaric Bupivacaine for Spinal Anesthesia in Cesarean Section
Subarachnoid block is a widely used anesthetic technique for cesarean section. To improve the quality of analgesia and prolong its duration, the addition of intrathecal opioids to local anesthetics has been encouraged.
- Trial name
- NCT04446715
- Testing
- sufentanil, meperidine, Bupivacaine
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- Makassed General Hospital
Postoperative Pain, Local Infiltration
Bupivacaine Infiltration and Postoperative Pain
This is a double-blind randomized controlled trial to assess the efficacy of local infiltration of bupivacaine versus placebo, in reducing postoperative pain.
- Conditions
- Postoperative Pain, Local Infiltration, Analgesia
- Trial name
- NCT04728308
- Testing
- Bupivacain
- Where
- Pakistan
- Volunteers
- 300 people
- Sponsor
- Armed Forces Hospital, Pakistan
Aortic Coarctation, Erector Spinae Plane Block
Erector Spinae Plane Block Versus Fentanyl Infusion in Pediatric Patients Undergoing Aortic Coarcitectomy
Pain is considered to be subjective, however in children it is believed to be felt rather than expressed, because they often depend on the caregiver for their safety and well-being.
- Conditions
- Aortic Coarctation, Erector Spinae Plane Block, Paediatric
- Trial name
- NCT04128540
- Testing
- Fentanyl, Erector spinae plane block
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Cairo University
Femur Fracture
Evaluation of the Postoperative Analgesic Efficacy of the Quadroiliac Plane (QIP) Block in Femur Fracture Surgery
The goal of this clinical trial is to learn whether the Quadroiliac Plane (QIP) block helps reduce postoperative opioid use in adults undergoing femur fracture surgery.
- Trial name
- NCT07009782
- Testing
- QIP block
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Osteoarthritis, Osteoarthritis, Knee
Intraoperative Liposomal Bupivacaine Injection in Primary Total Knee Arthroplasty
The purpose of the study is to evaluate the efficacy of local infiltration of liposomal bupivacaine versus use of an indwelling femoral peripheral nerve block in controlling early postoperative pain in primary total knee…
- Conditions
- Osteoarthritis, Osteoarthritis, Knee, Arthritis, Degenerative, Osteoarthrosis
- Trial name
- NCT02341079
- Testing
- Bupivacaine Liposome Injection, Indwelling femoral nerve block
- Where
- United States
- Sponsor
- United States Naval Medical Center, San Diego
Analgesia, Perioperative Analgesia
Ultrasound-Guided Parasternal/Rectus Sheath Block vs Erector Spinae Plane Block for Pain Control in Cardiac Surgery
The researchers are working to improve recovery after heart surgery by reducing reliance on opioids. Newer regional anesthesia techniques can provide strong pain relief with fewer risks, but the choice of method depends on each…
- Conditions
- Analgesia, Perioperative Analgesia, Regional Block Technique
- Trial name
- NCT07692659
- Testing
- Parasternal/ Rectus sheath block, Erector spinae plane block
- Volunteers
- 50 people
- Sponsor
- National Cancer Institute, Egypt
Adolescent Idiopathic Scoliosis, Juvenile Idiopathic Scoliosis
IV Methadone Vs EXPAREL Erector Spinae Plane Blockade in Pediatric Subjects Undergoing Idiopathic Scoliosis Correction
The goal of this pilot study is to assess the feasibility of conducting a randomized controlled trial at a single institution comparing erector spinae plane blockade (ESPB) with liposomal bupivacaine (LB, Exparel) to intravenous…
- Trial name
- AIMS (NCT05730920)
- Testing
- Methadone, Liposomal bupivacaine (LB, Exparel)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Dr. Casey Stondell, MD
Surgery
The Effects of Anesthetic Method on Cerebral Oxygen Saturation in Geriatric Patients Undergoing Transurethral Surgery
The effects of anesthetic method on cerebral oxygen saturation in geriatric patients undergoing transurethral surgery.
- Trial name
- NCT01147146
- Testing
- propofol, fentanyl, atracurium, bupivacaine, bupivacaine, Midazolam
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Yonsei University
General Anesthesia, Propofol Target-controlled Infusion
Effects of Epidural Local Anesthetics on Propofol Induction
The investigators designed a prospective, randomized, placebo-controlled study to determine whether thoracic epidural anesthesia(TEA) with different local anesthetics has different influences on the propofol dose during induction.
- Conditions
- General Anesthesia, Propofol Target-controlled Infusion, Thoracic Epidural Anesthesia
- Trial name
- NCT02000973
- Testing
- Lidocaine, Bupivacaine, Ropivacaine
- Volunteers
- 80 people
- Sponsor
- First Hospital of China Medical University
Anesthesia, Local
Preoperative Block for Anterior Cervical Spine Surgery
The purpose of this clinical trial study is to compare the analgesic effects of ultrasound-guided intermediate cervical plexus block Versus cervical erector spinae block in patients undergoing anterior cervical spine surgery.
- Trial name
- ESPB/ICPB (NCT06867510)
- Testing
- Block for Anterior Cervical Spine Surgery
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Postoperative Pain
Anterior Abdominal Blocks for Postoperative Pain Control in Obese Patients
The purpose of this study is to compare between two surgical techniques for anterior abdominal wall blocks in obese patients Undergoing Major Gynecological Surgery: Surgical Transversus Abdominis Plane [TAP] block versus Rectus…
- Trial name
- NCT03732027
- Testing
- Surgical Transversus Abdominis Plane Block, Surgical Rectus Sheath Block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Epidural Anesthesia
Comparison of the Effects of Epidural Analgesia and Local Infiltrative Analgesia Methods on Pain Control
Total knee arthroplasty (TKA) is one of the major orthopedic surgeries that cause severe postoperative pain. 60% of the patients undergoing TKA have severe pain and 30% have moderate pain postoperatively.
- Trial name
- NCT05344079
- Testing
- 18-Gauge Touhy (Egemen®, Combifix Standard Spinal Epidural Combined Set, İzmir, Turkey), 20-gauge infiltrative analgesia catheter connected to an ON-Q elastomeric pump
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Samsun Education and Research Hospital
Lumbar Disc Herniation
Plane Block vs Intravenous Patient Controlled Analgesia
Acute postoperative pain begins with surgical trauma and decreases with tissue healing. Untreatable postoperative pain is one of the most important problems due to the increase in respiratory, cardiac and thromboembolic…
- Trial name
- NCT04457986
- Testing
- Erector spina plane block (ESP), Modified thoracolumbar interfacial plane block (MTI), Intravenous patient controlled analgesia (IV-PCA)
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Diskapi Teaching and Research Hospital
Primary Total Knee Arthroplasty
The Efficacy of Local Infiltration Analgesia for Postoperative Pain Management After Total Knee Arthroplasty
This prospective, double-blinded, randomized controlled study evaluates the effects of peripheral nerve blocks with and without local infiltration analgesia for postoperative pain management after primary total knee arthroplasty.
- Trial name
- NCT04258241
- Testing
- Local infiltration analgesia with local anesthetic, Local infiltration analgesia without local anesthetic, Needle
- Where
- Lithuania
- Volunteers
- 80 people
- Sponsor
- Lithuanian University of Health Sciences
Analgesia
Erector Spinae Block Versus PECS Block Type II for Breast Surgeries
The purpose of this randomized, controlled prospective study is to compare the analgesic effect of US-guided ESP block versus PECs block in patients undergoing breast surgery for breast cancer in the National Cancer Institute…
- Trial name
- NCT04284124
- Testing
- Erector Spinae block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- National Cancer Institute, Egypt
Laryngeal Dystonia, Spasmodic Dysphonia
Understanding Disorder-specific Neural Pathophysiology in Laryngeal Dystonia and Voice Tremor
The researchers will examine functional neural correlates that differentiate between laryngeal dystonia and voice tremor and contribute to disorder-specific pathophysiology using a cross-disciplinary approach of multimodal brain…
- Conditions
- Laryngeal Dystonia, Spasmodic Dysphonia, Tremor
- Trial name
- NCT05216770
- Testing
- Brain imaging, Laryngeal sensory block with topical bupivacaine
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
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