Clinical trials: Bupivacaine
Osteoarthritis, Degenerative Joint Disease
Efficacy of Intraoperative Injections on Postoperative Pain Control During Total Hip Replacement
The purpose of this study is to clarify the efficacy of a multidrug versus single drug periarticular injection when only standard operative and postoperative pain management protocols used and the control group is exposed to what…
- Trial name
- NCT03119038
- Testing
- Bupivicaine + epinephrine, Bupivacaine, Ropivacaine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Gastric Cancer, Gastric Adenoma
The Efficacy of Topical Bupivacaine and Triamcinolone Acetonide Injection in the Relief of Pain After Endoscopic Submucosal Dissection for Gastric Neoplasia: A Randomized Double-blind, Placebo-controlled Trial
Although pain is a common complication of endoscopic submucosal dissection (ESD), management strategies are inadequate. bupivacaine is used for visceral pain control in chronic pain and in pain associated with surgery in clinical…
- Trial name
- NCT01961752
- Testing
- Saline, Bupivacaine + saline, Bupivacaine + triamcinolone acetonide
- Where
- South Korea
- Volunteers
- 111 people
- Sponsor
- Yonsei University
Pain, Anesthesia
Drug Concentration and Volume on Adequate Labor Analgesia With PIEB
Neuraxial labor analgesia is performed by the administration of a local anesthetic/opioid mixture in the epidural space. The delivery method is a combination of continuous infusion, provider-administered boluses and…
- Conditions
- Pain, Anesthesia, Labor Pain
- Trial name
- CADD2 (NCT03553576)
- Testing
- Low volume bolus, High volume bolus
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Northwestern University
Pulmonary Nodule, Liposomal Bupivacaine
Effect of Intercostal Nerve Block With Liposomal Bupivacaine on Quality of Recovery in VATS Partial Pneumonectomy
Video-assisted thoracoscopic surgery (VATS) is a minimally invasive approach for partial pneumonectomy, but postoperative pain remains a major challenge affecting recovery.
- Trial name
- NCT07512635
- Testing
- Bupivacaine Hydrochloride, Bupivacaine liposome
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Sanming First Hospital
Post Operative Pain Management
Efficacy of Erector Spinae Plane Block Versus Subcostal Transversus Abdominis Plane Block in Laparoscopic Nephrectomy
The investigators hypothesize that erector spinae plane block is better than subcostal transversus abdominis plane block regarding postoperative pain management.
- Trial name
- NCT06670508
- Testing
- Subcostal Transversus Abdominis Plane block, Erector Spinae Plane block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Sacroiliitis
Outcomes of Intra-articular Steroid Injection Via Ultrasound Guidance Versus Fluoroscopic Guidance in the Sacroiliac Joint in Patients With Sacroiliitis
Sacroiliitis is a common cause of low back and buttock pain. Intra-articular steroid injection of the sacroiliac joint can provide pain relief and functional improvement.
- Trial name
- NCT07791108
- Testing
- Ultrasound-guided intra-articular steroid injection
- Where
- Pakistan
- Volunteers
- 176 people
- Sponsor
- Allied Hospital Faisalabad
Rotator Cuff, Bankert Repair
Intrscalene Block Versus Pericapsular Nerve Group Block for Arthroscopic Shoulder Surgery
Early postoperative pain after arthroscopic shoulder surgery is a major problem for patients and orthopedic surgeons. Adequate pain control is vital for all aspects of patient recovery; including mental state, nutrition, cost of…
- Trial name
- NCT05668533
- Testing
- Interscalene versus PENG Block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Acute Appendicitis
Management of Acute Appendicitis Pain in the Emergency Department
This study aims to compare the effectiveness of TAP (Transversus Abdominal Plane) block, ESPB (Erector Spinal Plane Block), and tramadol in preoperative pain management for patients diagnosed with acute appendicitis and…
- Trial name
- NCT06808087
- Testing
- Transversus abdominis plane blockage, Erector spinae plane blockage, Tramadol
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Ankara City Hospital Bilkent
Pain, Postoperative
Perineural Versus IV Dexmedetomidine as Adjuvant to Quadratus Lamborum Block for Pediatrics Undergoing Pyeloplasty
this prospective parallel group double blinded study will be conducted over 50 pediatric patients ASA (American Association of Anesthesiologists) I and II between the age of 8-13 years old,who will be scheduled for laparoscopic…
- Trial name
- NCT03885804
- Testing
- Quadratus lamborum dexmedetomidine intravenous, Quadratus lamborum dexmedetomidine perineural group(
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Local Anesthetic, Ultrasound
TAP Block With Methyl-prednisolone as a Pain Treatment Modality After Total Abdominal Hysterectomy Procedures
The aim of this work to compare between the efficacy of ultrasound guided TAP block with dexamethasone as an adjuvant versus ultrasound guided TAPB with methyl prednisolone as an adjuvant to local anesthetic for postoperative…
- Conditions
- Local Anesthetic, Ultrasound, Pain, Acute
- Trial name
- NCT06131593
- Testing
- TAPB with dexamethasone as an adjuvant to local anesthetics, TAPB with methylprednisolone as an adjuvant to local anesthetics
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Kasr El Aini Hospital
Post Operative Pain, Cervical Spine Instability
Inter-semispinal Plane Block and Cervical Spine Surgery
The inter-semispinal plane (ISP) block is a novel ultrasound-guided technique that involves local anesthetic injection into the fascial plane between the semispinalis cervicis and semispinalis capitis muscles with subsequent…
- Trial name
- ISPB (NCT06003933)
- Testing
- Bupivacaine Hydrochloride, Lidocaine Hydrochloride, Ultrasound
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Yasser S Mostafa, MD
Myocardial Revascularization, Spinal Anesthesia
Spinal Anesthesia Associated With General Anesthesia in Coronary Artery Bypass
CONTEXT: In patients eligible for coronary artery bypass surgery, anesthesia should provide a number of conditions that exceed the limits of cardiovascular stability, myocardial protection and other organs.
- Conditions
- Myocardial Revascularization, Spinal Anesthesia, Postoperative Care, Fentanyl
- Trial name
- NCT02840006
- Testing
- General anesthesia only, General anesthesia and Spinal anesthesia
- Where
- 2 sites in Brazil
- Volunteers
- 60 people
- Sponsor
- Daniel Gioielli de Castilho
Breast Cancer
Comparison of Paravertebral Block With General Anesthesia in Patients Undergoing Breast Cancer Surgery
The purpose of this project is to determine if there is a difference between paravertebral block and general anesthesia in terms of time to discharge from the Post-Anesthesia Care Unit and pain level in patients undergoing…
- Trial name
- NCT00645138
- Testing
- Paravertebral Block, General Anesthesia
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Weill Medical College of Cornell University
Anesthesia, Local
Analgesic Effect of Illiohypogastic & Ilioinguinal Nerve Block in TAVR - TF (Prospective Randomized Study)
The purpose of the study is to compare the effect of illiohypogastric and ilioinguinal nerve block with the local infiltration with lidocaine in patients undergoing TAVI
- Trial name
- NCT06362915
- Testing
- Lidocaine, Bupivacain
- Where
- 2 sites in Egypt
- Volunteers
- 52 people
- Sponsor
- Ain Shams University
Anesthesia, Local
Liposomal Bupivacaine Versus Bupivacaine for for Postoperative Pain Control in Shoulder Surgery
This is a randomized, single blinded clinical trial whose purpose is to assess the impact of liposomal bupivacaine (LB) in a single shot interscalene nerve block compared with standard bupivacaine (same dose) in a single shot…
- Trial name
- NCT04180943
- Testing
- interscalene nerve block
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Bassett Healthcare
Post Operative Pain
Analgesic Effect of M-TAPA and TAPB on Laparoscopic Cholesistectomy
Cholecystectomy is the most frequently performed abdominal surgery in developed nations, with laparoscopic cholecystectomy being recognized as the gold standard technique for treating gallstones.
- Trial name
- NCT06662617
- Testing
- modified thoracoabdominal nerve block through perichondrial approach, Transversus Abdominal Plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Amputation Stumps, Neuroma
Pathophysiology of Post Amputation Pain
The purpose of this study is to see how Post Amputation Pain (PAP) affects the body and brain by using sensory testing (such as pinprick testing), taking pictures of your brain (using a functional magnetic resonance imaging…
- Trial name
- PPAP (NCT01632709)
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Postoperative Pain, Minimal Invasive Cardiac Surgery
Serratus Anterior Plane Block and Serratus Anterior Plane Block + Continuous Wound Infiltration With Catheter
A total of 46 patients scheduled to undergo elective coronary artery bypass surgery via a minimally invasive technique will be included in the study.
- Trial name
- MICS (NCT06971432)
- Testing
- Group SAPB, Group SAPB + LIA
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Ankara City Hospital Bilkent
Anaesthesia Conduction
Awake Local Anesthesia Infiltration Compared to Regional Nerve Block for Hand Surgeries
The study trying to fined out the best anaesthesia technique for hand flexor procedures which provide efficient anaesthesia while providing adequate surgical field exposure \& less blood loss
- Trial name
- NCT05767944
- Testing
- local anaesthesia infiltration, brachial plexus block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Pain and Discomfort During Scaling and Root Planning of Patients With, Periodontitis
Effect of Local Anesthesia in Patients With Marginal Periodontitis Undergoing Scaling and Root Planning
A randomised cross-over study comparing two methods of local anaesthesia for patients diagnosed with periodontitis undergoing scaling and root planning.
- Trial name
- NCT01878864
- Testing
- Bupivacaine lozenge, Lidocaine-adrenalin injection
- Where
- 3 sites in Denmark
- Volunteers
- 12 people
- Sponsor
- Ove Andersen
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