Clinical trials: Bupivacaine
Gynecologic Disease Requiring Vaginal Operation Under Neuraxial Anesthesia
Regional Blocks of Gynecological Surgeries
This study will be conducted on 273 patients of ASA grade I and II aged from 25 to 55 years and presented for elective vaginal surgeries such as vaginal hysterectomy, repair of prolapse Patients will be divided into three equal…
- Trial name
- NCT03790748
- Testing
- Standard Lumbar Epidural Technique, 25G Dural Puncture Epidural Technique, 27G Dural Puncture Epidural Technique
- Where
- 2 sites in Egypt
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anesthetics, Local
Heavy Bupivacaine in Peribulbar Block
Most of the ophthalmic procedures are performed under local anesthesia as the patient is often elderly and with diseases. This may increase the risk of morbidity and mortality under general anesthesia.
- Trial name
- NCT03312959
- Testing
- hyperbaric bupvacaine in Peribulbar block, isobaric bupvacaine in Peribulbar block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Pain, Postoperative
Efficacy and Safety of the CollaRx Bupivacaine Implant Compared to the ON-Q Painbuster Following Abdominal Hysterectomy
The purpose of this study is to determine whether the CollaRx Bupivacaine Implant is safe and effective in reducing the amount of narcotic pain medication needed to control pain during the first 96 hours after abdominal…
- Trial name
- NCT00749749
- Testing
- Bupivacaine Collagen Sponge (CollaRx Bupivacaine Implant), ON-Q PainBuster Post-op Pain relief System
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Innocoll
Sleep Apnea Syndromes
Impact of Intrathecal Morphine on Sleep Apnea Syndrome
Intrathecal morphine is commonly used as an analgesic adjunct for hip arthroplasty performed under spinal anaesthesia. Sleep apnea syndrome is a condition that affects up to 10% of the patients.
- Trial name
- NCT02566226
- Testing
- Bupivacaine with normal saline, Bupivacaine with intrathecal morphine
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Local Anesthesia, Analgesia Disorder
Intermediate Cervical Block Under Ultrasound for Thyroid Surgery: Impact on Per and Postoperative Opioid Consumption
The investigators included prospectively 35 patients undergoing an intermediate cervical block under ultrasound (GP1) before a thyroidectomy ,compared to a group of 35 patients without a block (GP2).
- Trial name
- ICPBUS (NCT03107585)
- Testing
- bilateral cervical plexus block
- Where
- Tunisia
- Volunteers
- 70 people
- Sponsor
- University Hospital, Mahdia
Perioperative/Postoperative Complications
The Effects of Dexmedetomidine on Peroperative Shivering Incidence Under Spinal Anesthesia
The purpose of this study to compare the efficacy of intravenous or intrathecal dexmedetomidine on the incidence of shivering on patients who scheduled spinal anesthesia for elective surgery.
- Trial name
- NCT01921361
- Testing
- Levobupivacaine, Dexmedetomidine, sodium chloride
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- TC Erciyes University
Post Operative Pain
Evaluation of the Analgesic Effect of Midazolam and Ketamine as an Additive to Intrathecal Bupivacaine in Patients Undergoing Cesarean Section
Objective :To compare the analgesic effect of intrathecal midazolam and ketamine as an additive to bupivacaine in patients undergoing cesarean section .
- Trial name
- NCT01404442
- Testing
- Ketamine, Midazolam
- Where
- Iran
- Volunteers
- 90 people
- Sponsor
- Qazvin University Of Medical Sciences
Analgesia Duration
Dexamethasone and Lower Extremity Block Duration
Dexamethasone has shown to prolong upper extremity blocks. No one ha studied its effect on lower extremity blocks. The study would evaluate that point.
- Trial name
- NCT01756586
- Testing
- Dexamethasone, Bupivacaine
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Chicago
Pain, Postoperative
Bupivacaine With or Without Dexmedetomidine for Postoperative Pain Relief in Abdominal Surgery
This study investigates the effectiveness of adding dexmedetomidine to bupivacaine for postoperative analgesia in patients undergoing abdominal surgeries.
- Trial name
- NCT07285083
- Testing
- Bupivacaine with Dexmedetomidine (TAP Block), Bupivacaine (TAP Block)
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Sheikh Zayed Medical College
Pain, Postoperative, Anesthesia
The Efficacy of Serratus Anterior Plane Block (ESAPB) for Thoracotomy: a Prospective Study
Thoracotomy is considered the most painful surgical procedure. Ultrasound-guided serratus anterior plane block (SAPB) is a relatively new truncal block method treating thoracotomy pain.
- Conditions
- Pain, Postoperative, Anesthesia, Thoracotomy
- Trial name
- NCT03839160
- Testing
- Serratus anterior plane block, Intravenous patient-controlled-analgesia morphine
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shanghai Zhongshan Hospital
Pain, Acute, Opioid Use
Postoperative Pain Scores and Opioid Consumption in Video Assisted Thoracic Surgery
Video assisted thoracoscopic surgery (VATS) is a type of minimally invasive thoracic surgery (MITS) procedure used for diagnosis or treatment of chest pathologies (pulmonary, mediastinal, chest wall).
- Trial name
- EsPITHX (NCT04459923)
- Testing
- ultrasound-guided erector spinae plane block catheter, thoracic epidural catheter
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ataturk University
Postoperative Pain, Hip Surgery
Comparison of QIPB and SIFICB in Hip Surgery
The aim is to compare the postoperative analgesic effects of Quadroiliac Plane Block (QIPB) and Suprainguinal Fascia Iliaca Compartment Block (SIFICB) in patients undergoing hip surgery.
- Trial name
- NCT07233746
- Testing
- Quadro-İliac Plane Block(QİPB), Suprainguinal Fascia Iliaca Compartiment Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cumhuriyet University
Hand Injuries, Hand Injuries and Disorders
Early Ultrasound-guided Nerve Block for Painful Hand Injuries in the Emergency Department
This study aims to determine whether early initiation of temporary nerve block therapy improves patient satisfaction, decreases patient pain and discomfort, decreases the use of dangerous medications such as narcotics, and frees…
- Trial name
- NCT03195413
- Testing
- Ultrasound-guided forearm nerve block, 1:1 volume measured solution of: 1% lidocaine without epinephrine and 0.5% bupivacaine without epinephrine, Bedside ultrasound machine
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Washington
Postoperative Pain
Quadratus Lumborum Block vs Intrathecal Morphine for Post-Cesarean Analgesia
İn this study, planned to compare the post-operative analgesic efficacy of Intrathecal Morphine Administration and anterior Quadratus lumborum Block in elective cesarean section operations.
- Trial name
- NCT06612424
- Testing
- ANTERİOR QUADRATUS LUMBORUM BLOCK, İNTRATECHAL MORPHİNE GROUP
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Spinal Anesthesia, Epidural; Anesthesia
Bupivacaine With Epidural Volume Extension
In this study the investigator will address the efficacy of using low dose bupivacaine spinal anesthesia (SA) in combination with epidural volume extension (EVE) for patients undergoing short obstetric procedures.
- Trial name
- NCT03110003
- Testing
- 10 mg Bupivacaine, 5 mg Bupivacaine
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Subacromial Impingement Syndrome
Effectiveness of Supervised Exercise Program in Subacromial Impingement Syndrome
Subacromial Impingement Syndrome (SIS) is a pathology resulting from mechanical repetitive compression and inflammation of the supraspinatus tendon, subacromial bursa and biceps tendon under the acromion and the coracoacromial…
- Trial name
- NCT04186624
- Testing
- Subacromial-subdeltoid bursa corticosteroid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Marmara University
Block
Ultrasound Guided QLB III Versus Intrathecal Morphine for Analgesia After Cesarean Section
Subarachnoid morphine (SAM) is the gold standard for treating postoperative pain after cesarean delivery (CD) but it has undesirable side effects, that's why the aim of our study is to identify whether ultrasound-guided Quadratus…
- Trial name
- QLB (NCT03428880)
- Testing
- Morphine, Quadratus lumborum block
- Where
- 2 sites in Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Pain, Anesthesia
Effects of Anesthetic Technique on NK Cells
The proposed study is a pilot prospective, single-blinded, randomized controlled trial evaluating the effects of two routine, standard-of-care, anesthetic techniques on natural killer cell population size and cytotoxicity in…
- Conditions
- Pain, Anesthesia, Cancer
- Trial name
- NCT02669186
- Testing
- Bupivacaine + Fentanyl, Bupivacaine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Arthropathy Shoulder
Liposomal Bupivacaine Interscalene Nerve Block in Shoulder Arthroplasty
The objective of this study is to determine if peripheral nerve block with liposomal bupivacaine in combination with standard bupivacaine will prolong the duration of block, improve pain scores, and decrease opioid utilization in…
- Trial name
- NCT03663283
- Testing
- Liposomal Bupivacaine, Bupivacaine Hydrochloride
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Mayo Clinic
Postoperative Pain
Femoral Nerve Block, Periarticular Nerve Group (PENG) Block, and Preoperative IV Fentanyl
The pericapsular nerve group block is a regional anesthetic technique described in 2018, developed primarily in total hip arthroplasties for postoperative analgesia with motor sparing benefits.
- Trial name
- NCT06537323
- Testing
- Femoral nerve block with0.25% bupivacaine guided by ultrasound., PENG block with0.25% bupivacaine guided by ultrasound., Preoperative IV fentanyl 100microgram
- Where
- Egypt
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Aswan University Hospital
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