Clinical trials: Bupivacaine
Breast Cancer Female
PEMF and PEC Blocks in Mastectomy Reconstruction Patients
This is a prospective randomized controlled double-blind interventional study comparing the effect of pulsed-electromagnetic field device (PEMF), pectoral interfascial block (PIB), and placebo on postoperative pain control.
- Trial name
- NCT03360214
- Testing
- Bupivacaine Hydrochloride, Pulsed Electromagnetic Field (PEMF) Device, Ropivacaine Hydrochloride
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Columbia University
Nerve Block, Coronary Artery Bypass
Comparison of Erector Spinae Plane Block and Transversus Thoracic Muscle Plane Block in Coronary Artery Surgery
The main objective of this study is to evaluate postoperative pain intensity comparatively between erector spinae plane block and transversus thoracic muscle plane block in patients undergoing open coronary artery surgery.
- Conditions
- Nerve Block, Coronary Artery Bypass, Anesthesia and Analgesia
- Trial name
- NCT06709625
- Testing
- Transversus thoracis plane block, Erector spina plane block (ESP)
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Ankara City Hospital Bilkent
Vertebral Compression Fracture, Kyphoplasty
Anesthesia for Percutaneous Kyphoplasty
The aim of this study was to compare ESP with conventional local infiltration anesthesia (CLIA) and extrapedicular infiltration anesthesia (EPIA) with respect to analgesic efficacy in patients underwent elective PKP for VCF.
- Trial name
- Kyphoplasty (NCT07091513)
- Testing
- group ESP
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Lower Extremity Fractures.
A Study of Postsurgical Pain Control for Lower Extremity Fractures
Postsurgical pain may effectively be treated with a multimodal approach that incorporates the use of local anesthetics. Bupivacaine is a local anesthetic that has been proven to be effective at reducing postsurgical pain.
- Trial name
- NCT02214810
- Testing
- Bupivacaine/Exparel
- Where
- United States
- Sponsor
- Broward Health
Hemiplegic Shoulder Pain
Suprascapular Nerve Block Versus Intraarticular Steroid Injection in Hemiplegic Shoulder Pain
Suprascapular nerve block versus(vs) intra-articular steroid injection in the management of hemiplegic shoulder pain (HSP): a randomised, double blinded, controlled trial BACKGROUND Hemiplegic shoulder pain (HSP) is a common…
- Trial name
- NCT04128605
- Testing
- Suprascapular nerve block (SSNB), Intraarticular shoulder steroid injection (IAS)
- Where
- Malaysia
- Volunteers
- 86 people
- Sponsor
- University of Malaya
Neuromuscular Blockade, Regional Anesthesia
Bilateral Transversus Abdominis Plane Block Versus Atracurium During Laparoscopic Gynecology Procedures.
A monocentric, prospective, randomized controlled trial, including patients proposed for a laparoscopic gynecologic surgery comparing the muscular relaxing effect of a bilateral ultrasound-guided Transversus Abdominis Plane block…
- Trial name
- NCT03701256
- Testing
- Bilateral ultrasound guided TAP bloc, Neuromuscular blockade agent: Atracurium 01mg/kg per bolus
- Where
- Tunisia
- Volunteers
- 100 people
- Sponsor
- University Tunis El Manar
Interscalene Nerve Block, Suprascapular Nerve
Suprascapular and Axillary Versus Interscalene Blocks Regarding Phrenic Affection in Shoulder Surgeries
This study is aims to compare between combined suprascapular and axillary nerve blocks versus interscalene nerve block regarding phrenic nerve affection assessed by ultrasound guided diaphragmatic excursion in shoulder…
- Conditions
- Interscalene Nerve Block, Suprascapular Nerve, Shoulder Surgery
- Trial name
- NCT06674551
- Testing
- Suprascapular nerve block and Axillary nerve block, Interscalene Nerve Block
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Postoperative;Pain Management
Effects of Serratus Posterior Superior Intercostal Plane Block and Pectoralis Nerve Block in Coronary Artery Surgery
Postoperative analgesia is a critical risk factor for the development of pulmonary and cardiovascular complications in all types of chest surgery, particularly coronary artery bypass graft (CABG) surgery.
- Trial name
- NCT06242431
- Testing
- Group serratus posterior superior intercostal plane block (SPSIPB), Group pectoralis nerve block (PECS-II)
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Hitit University
Femoral Neck Fractures, Hemiarthroplasty
Efficacy of Intraoperative Periarticular Injections in Hip Fracture Hemiarthroplasty
The objective of this study was to assess the effectiveness of the intraoperative periarticular solution in reducing blood loss and minimizing transfusion requirements in patients with femoral neck fractures who underwent…
- Conditions
- Femoral Neck Fractures, Hemiarthroplasty, Blood Loss Requiring Transfusion
- Trial name
- NCT06701695
- Testing
- Periarticular Injection (PAI), Control (Standard treatment)
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Ankara City Hospital Bilkent
Postherpetic Neuralgia
Single-dose to Evaluate the Pharmacokinetics of GTX-101 and Subcutaneous Injectable Bupivacaine in Healthy Subjects
This is a single-center, randomized, single-dose, active-controlled study in healthy male and female subjects. The study will enroll subjects to evaluate the PK of 3 dose strengths (50 mg, 100 mg and 200 mg) of GTX-101 compared…
- Trial name
- NCT05517486
- Testing
- GTX-101, Bupivacaine HCl subcutaneous injection
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Grace Therapeutics Inc.
Nerve Block
Pain Management in Laparoscopic Cholecystectomies
Erector spinae plane (ESP) block is a more recent method than paravertebral block (PVB) and has a lower risk of complications. The aim of this study was to compare postoperative analgesia requirements and side-effects in terms of…
- Trial name
- NCT05837702
- Testing
- ESPB, PVB, CONTROL
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Giresun University
Hip Fractures
Optimization of Analgesia for Hip Fracture Patients
Hip Fracture is a common orthopedic emergency in elderly people, which causes moderate to severe pain. Until now, different methods of pain treatment have been used, including pain-killer medication, which given in to the vein…
- Trial name
- NCT03609645
- Testing
- Fascia iliaca block, Femoral articular branches block(FAB)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Anesthesia
Serratus Anterior Plane Block Versus Erector Spinae Plane Block. for Thoracotomy in Pediatric Patients
This randomized controled trial is designed to compare efficacy and safty of serratus anterior plane block versus erector spinae plane block for thoracotomy in pediatric patients.
- Trial name
- NCT04933877
- Testing
- Fascial plane block
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Chronic Pancreatitis, Chronic Pain
Extracorporeal Shock Wave Lithotripsy and Endotherapy for Pain in Chronic Pancreatitis
Pain is a common symptom of chronic pancreatitis and remains a significant therapeutic challenge. In patients with pathological changes of the pancreatic duct, including stones and strictures, endoscopic procedures with or…
- Trial name
- SCHOKE (NCT03966781)
- Testing
- ESWL, ERCP
- Where
- India
- Volunteers
- 106 people
- Sponsor
- Asian Institute of Gastroenterology, India
Post-operative Pain
The Pectoralis (PECS2) Block Versus Intrathecal Morphine
50 patients with American Society of Anesthesiologists (ASA) grade I to II, 18 to 60 years of age scheduled for Modified Radical Mastectomy surgery, Will be included in the study.
- Trial name
- NCT06016205
- Testing
- intrathecal morphine injection, ultrasound guided PECS2 block
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Cholecystectomy, Laparoscopic, Pain, Postoperative
Effect of Pre- and Postoperative ESP Block on Frontal QRS-T Angle in Laparoscopic Cholecystectomy
This study aims to investigate the effects of preoperative and postoperative Erector Spinae Plane (ESP) block on the frontal QRS-T angle, a marker of cardiac electrophysiological instability, in patients undergoing laparoscopic…
- Conditions
- Cholecystectomy, Laparoscopic, Pain, Postoperative, Electrocardiography, Regional Anesthesia
- Trial name
- NCT07058194
- Testing
- Preoperative Erector Spinae Plane Block, Postoperative Erector Spinae Plane Block, Standard General Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Harran University
Rescue Analgesia
Comparison of Rescue Analgesia Requirement in Patients Undergoing Laparoscopic Cholecystectomy After Transversus Abdominal Plane (tap) Block Vs Local Anesthetic Wound Infiltration At the End of Surgery
patients undergoing laparoscopic cholecystectomy will be diveided into 2 groups A \& B . Group A will receive local anesthetic wound infiltration and group B will receive Transversus abdominal plane block as a post operative…
- Trial name
- TAP (NCT06803966)
- Testing
- Post Operative Analgesia
- Where
- Pakistan
- Volunteers
- 74 people
- Sponsor
- Fazaia Ruth Pfau Medical College
Postoperative Pain Management
Postoperative Recovery Quality After Cesarean Section: Comparing Erector Spinae and Retrolaminar Blocks Using Turkish Version of the Obstetric Quality-of-Recovery Score in a Turkish Cohort (ObsQoR-11T)
Study Design This retrospective observational study aims to evaluate and compare the effects of two regional anesthesia techniques, Erector Spinae Plane (ESP) block and Retrolaminar Block (RLB), on postoperative recovery quality…
- Trial name
- NCT07181902
- Testing
- Erector Spinae Plane Block (ESP), Retrolaminar Block (RLB)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Post-Op Complication, Pain, Postoperative
TAP Block On Abdominal Surgery Patients With General Anesthesia
INTRODUCTION: The aim of this study was to investigate the effects of tranversus abdominis plane (TAP) block placed postoperatively using ultrasound guidance for patients with caesarean section, myomectomy and hysterectomy under…
- Trial name
- TAPBLOCK (NCT04364477)
- Testing
- transversus abdominis plane (TAP) block
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University Hospital
Nerve Block
Pectoral Nerve Block and Serratus Posterior Superior Intercostal Plane Block in Breast Cancer Surgery
This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Pectoral Nerve Block (PECS II) and the Serratus Posterior Superior Intercostal Plane (SPSIP) Block in patients undergoing breast cancer…
- Trial name
- NCT07001657
- Testing
- SPSIP Block, PECS II Block
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people
- Sponsor
- Antalya Training and Research Hospital
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