Clinical trials: Bupivacaine
Stress Urinary Incontinence
Voiding Function After Mid-Urethral Slings With and Without Local Anesthetic: Randomized Controlled Trial
The purpose of this study is to determine if there is a difference in post-operative voiding function between subjects receiving local anesthetic and those receiving placebo at the time of mid-urethral sling placement.
- Trial name
- URINE&ME (NCT01583166)
- Testing
- Bupivacaine, Saline, Epinephrine
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Massachusetts, Worcester
Post Operative Pain
Quadratus Lumborum Plain Block Versus Fascia Iliac Block
evaluation the efficacy of Quadratus Lumborum plain Block Versus Fascia Iliac Block for postoperative pain after hip surgery
- Trial name
- NCT05920265
- Testing
- Quadratus Lumborum plain Block, fascia iliaca block, control group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Minia University
Postoperative Pain, Abdominal Surgery
Bupivacaine Effectiveness and Safety in SABER® Trial
This is a research study testing SABER-Bupivacaine (an experimental pain-relieving medication). SABER-Bupivacaine is designed to continuously deliver bupivacaine, a common local anesthetic, for a few days in order to treat local…
- Trial name
- BESST (NCT01052012)
- Testing
- SABER-Bupivacaine, Bupivacaine HCl
- Where
- 26 sites in United States, Australia and 1 more
- Volunteers
- 331 people
- Sponsor
- Durect
Laparoscopic Cholecystectomy
Adding Magnesium Sulfate or Dexmedetomidine to Bupivacaine in Oblique Subcostal Tap Block for Laparoscopic Cholecystectomy: A Randomized Double -Blind Controlled Study
Laparoscopic cholecystectomy (LC) is one of the commonly performed surgical procedures associated with a moderate degree of postoperative pain especially on the 1st postoperative day.
- Trial name
- NCT06743919
- Testing
- Magnesium sulfate 50% - 1g/h, dexmedetomidine 0.5 µg/kg IV, Bupivacaine
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Assiut University
Postoperative Pain
PK and Safety After C-Section
The main goal of the study was to measure the amount of the active ingredients and other components of HTX-011 in plasma and expressed breast milk over time following postpartum administration in women undergoing a planned…
- Trial name
- NCT03955211
- Testing
- HTX-011, ZYNRELEF kit components for administration, MMA regimen
- Where
- 4 sites in United States
- Volunteers
- 25 people
- Sponsor
- Heron Therapeutics
Pain
Erector Spinae Plane Block for Carotid Endarterectomy
The purpose of this study is to test the hypothesis that erector spinae plane block will decrease intraoperative local anesthetic and postoperative analgesic consumption in patients undergoing carotid endarterectomy.
- Trial name
- NCT04224844
- Testing
- Erector spinae plane block, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Antalya Training and Research Hospital
Pneumonia, Cardiac Surgery
Catheter Outcomes With Sternotomy Cardiac Operated
Pneumonia occurs frequently in patients undergoing cardiac surgery and allows to increase their mortality. While chest physical therapy plays a crucial role to prevent postoperative pneumoniae, painful mobilization of the sternum…
- Conditions
- Pneumonia, Cardiac Surgery, Multiperforated Catheter, Analgesia
- Trial name
- STERNOCAT (NCT01648777)
- Testing
- L bupivacaine
- Where
- France
- Volunteers
- 1,502 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Post-mastectomy Pain Syndrome
Efficacy of Glucose in Serratus Anterior Plane Block to Reduce the Occurrence of Chronic Post-mastectomy Pain
Nearly 50% of patients suffer from chronic pain following breast cancer surgery. Several regional anesthesia techniques, including paravertebral block, erector spinae plane block, pectoral nerves block, and serratus anterior…
- Trial name
- NCT06443619
- Testing
- unilateral USG-deep SAPB with glucose, unilateral USG-deep SAPB without glucose
- Volunteers
- 190 people
- Sponsor
- Mansoura University
Pain Management, Postoperative Acute Pain
Effect of Sedation After Ultrasound-Guided Spinal Anesthesia on Back Pain
This study will evaluate whether giving sedation before spinal anesthesia, when performed with ultrasound guidance, reduces the risk of developing back pain after surgery.
- Conditions
- Pain Management, Postoperative Acute Pain, Chronic Back Pain
- Trial name
- NCT07198412
- Testing
- Ultrasound-guided spinal anesthesia, Midazolam plus ultrasound-guided spinal anesthesia, Landmark-guided spinal anesthesia
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Benha University
Osteosarcoma, Analgesia
Efficacy of Epidural Analgesia in Lower Extremity Osteosarcoma
In this study, the investigators aim to reduce complications in orthopedic malignancy surgeries and to increase the quality of life of patients who will be operated on.
- Trial name
- NCT04945512
- Testing
- Epidural Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Istanbul University
Emergence Agitation, Emergence Delirium, Anesthesia
Efficacy of Ultrasound-guided Greater Auricular Nerve Block in Preventing Postoperative Emergence Agitation in Pediatric Patients Undergoing Microscopic Middle Ear Surgery.
This study is designed to evaluate the effectiveness of ultrasound-guided greater auricular nerve block (GAN) on the reduction of emergence agitation (EA) occurrence and EA severity in children who are receiving general…
- Conditions
- Emergence Agitation, Emergence Delirium, Anesthesia, Emergence From Anesthesia, Emergence Delirium
- Trial name
- NCT07435675
- Testing
- ultrasound-guided greater auricular nerve block (GANB)
- Where
- Egypt
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Cholelithiasis, Cholecystectomy, Laparoscopic
Unilateral Laparoscopic TAP Block vs. Local Infiltration in Post-Cholecystectomy Analgesia
This study compared different methods of pain control after laparoscopic gallbladder removal. A total of 160 patients were randomly assigned to receive either a unilateral laparoscopic TAP block, local anesthetic infiltration, a…
- Conditions
- Cholelithiasis, Cholecystectomy, Laparoscopic, Pain, Postoperative, Anesthesia, Local
- Trial name
- TAP vs LAI (NCT07176299)
- Testing
- Unilateral laparoscopic TAP block (0.25% bupivacaine), Local anesthetic infiltration (0.25% bupivacaine), Combined TAP block and local anesthetic infiltration (0.25% bupivacaine)
- Where
- Poland
- Volunteers
- 160 people
- Sponsor
- University of Warmia and Mazury in Olsztyn
Pain
Study : LEVOBUPIVACAINE Versus Placebo
The locoregional anaesthesia is increasingly important in surgical practice, often allowing to simplify per- and post-operative analgesia.
- Trial name
- LEVOBU (NCT00621907)
- Testing
- chirocaine (Levobupivacaine), sodium chloride
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Breast Surgery
Serratus Posterior Superior Intercostal Plane Block, Versus Erector Spinae Facial Plane Blocks
Mastectomy is currently the most effective treatment for breast cancers in women. postoperative pain management carries a high degree of difficulty, as the breast has complex innervation involving the intercostal (T1-T7)…
- Trial name
- NCT06989372
- Testing
- serratus posterior superior block, erector spinae block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Hip Ostearthritis
Femoral and Obturator Nerve Articular Branches Prf
In our clinic, patients undergoing pulsed radiofrequency treatment of the femoral and obturator nerve articular branches under ultrasound guidance for pain management due to hip and groin pain associated with hip osteoarthritis…
- Trial name
- NCT07190339
- Testing
- ultrasound-guided femoral and obturator nerve articular branches pulsed radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Diskapi Teaching and Research Hospital
Abdominal Hysterectomy
The Effect of Two Different Analgesic Techniques on Postoperative Recovery Quality
Hysterectomy is one of the most frequently performed surgical procedures after Caesarean section in many countries of the world and involves the removal of the uterine corpus with or without the cervix (total hysterectomy) or…
- Trial name
- NCT06766994
- Testing
- intrathecal morphine, Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ataturk University
Impacted Third Molar Tooth
Articaine and Bupivacaine in Impacted Tooth Surgery
Articaine is a common local anesthetic used in oral surgery and belongs to the amide group of it has fast onset with little side effects.
- Trial name
- NCT04645888
- Testing
- Impacted tooth surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Shoulder Pain
Evolution of Post-Stroke Shoulder Pain With a Capsular Pattern With Physiotherapy Alone Versus Coupled With Mild Arthrographic Distension With Cortisone
The purpose of this study is to assess the efficacy of mild hydraulic distension with intra-articular corticosteroid injection for the treatment of subacute hemiparetic shoulder pain with a capsular pattern of restricted shoulder…
- Trial name
- NCT05845125
- Testing
- Physiotherapy alone, Glenohumeral injection of 40mg (1cc) of Triamcinolone and 7cc of 0.5% Bupivacaine coupled with physiotherapy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Claire Bourgeois
Post Operative Pain
A Trial of Levator Muscle Blocks Following Posterior Colporrhaphy Surgery to Reduce Post-operative Pain.
To determine if levator muscle block with bupivacaine improves postoperative pain control relative to placebo controls among women undergoing prolapse surgery involving a posterior colporrhaphy.
- Trial name
- NCT03067168
- Testing
- Bupivacaine, normal saline 0.9%
- Where
- 3 sites in United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- The Christ Hospital
Hip Replacement
Quadratus Lumborum Block Versus Fascia Iliaca Nerve Block for Patients Undergoing Total Hip Replacement
Investigators hypothesise that for patients undergoing elective total hip replacements, a single injection Transmuscular Quadratus Lumborum (TQL) block, when compared to a single injection Fascia Iliaca Block (FIB), will provide…
- Trial name
- NCT03551860
- Testing
- TQL, FIB
- Where
- Ireland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Adelaide and Meath Hospital, incorporating The National Children's Hospital
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