Clinical trials: Bupivacaine
Interstitial Cystitis, Bladder Pain Syndrome
Clinical Trial Comparing Two Bladder Instillations for IC/BPS
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a condition that results in long-term bladder and pelvic pain. IC/BPS affects women more often than men. How the disorder develops is not completely known.
- Trial name
- NCT03463915
- Testing
- Bladder instillation WITH triamcinolone acetonide, Bladder instillation WITHOUT triamcinolone acetonide
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Olivia Cardenas-Trowers, M.D.
Liver and Intrahepatic Bile Duct Disorder
Thoracic Epidural Analgesia or Four-Quadrant Transversus Abdominus Plane Block in Reducing Pain in Patients Undergoing Liver Surgery
This phase III trial studies how well thoracic epidural analgesia or four-quadrant transversus abdominus plane block works in reducing pain in patients undergoing liver surgery.
- Trial name
- NCT03214510
- Testing
- Bupivacaine, Fentanyl, Hydromorphone Hydrochloride
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- M.D. Anderson Cancer Center
Pain, Postoperative
Pharmacokinetics of Levobupivacaine After Cesarean Section
Transversus abdominis plane (TAP) block provides effective analgesia and is now a standard of care for analgesia after cesarean section. There is no information on levobupivacaine pharmacokinetics post TAP after pregnancy.
- Trial name
- NCT02852720
- Testing
- Levobupivacaine, Spinal anesthesia, Peripheral vein canulation
- Where
- Chile
- Volunteers
- 12 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Breast Cancer Surgery, Postoperative Analgesia
Ultrasound Guided Rhomboid Intercostal and Subserratus Plane Block in Breast Cancer Surgeries
Postoperative analgesia after breast cancer surgery is a challenge for anesthesiologists due to the complex innervation of the breast.
- Trial name
- NCT04336917
- Testing
- Rhomboid Intercostal and Subserratus Plane Block with local anesthetic
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Konya Meram State Hospital
Gynecologic Disease
Quadratus Lumborum Block vs Erector Spinae Plane Block in Laparoscopic Hysterectomy
Postoperative pain following laparoscopic hysterectomy is a challenging concern as some patients suffer acute pain that could let to chronic pain over time following the surgery.
- Trial name
- NCT05465525
- Testing
- Quadratus Lumborum Block Type III, Erector Spinae Plane Block, No Block
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Namik Kemal University
Breast Cancer, Breast Neoplasms
ESPB and RIB for Pain Management Following Mastectomy Surgery
Postoperative pain is an important issue in patients underwent mastectomy and axillary dissection surgery. Postoperative effective pain treatment provides early mobilization and shorter hospital stay.
- Conditions
- Breast Cancer, Breast Neoplasms, Breast Cancer Female
- Trial name
- NCT04752150
- Testing
- Analgesia management; group ESPB and RIB
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Bursitis
Steroid Injection for the Treatment of Greater Trochanteric Pain Syndrome
The objective of this study is to conduct a randomized, single-blinded placebo controlled trial comparing two modalities for the treatment of pain and mobility associated with trochanteric bursitis: (1) injection of…
- Trial name
- NCT00863889
- Testing
- Depomedrol injection, Lidocaine, Marcaine
- Where
- United States
- Sponsor
- Emory University
Anesthesia, Regional
Safety and Efficacy of Three Local Block Techniques for Diabetic Foot Surgery
Diabetic patients suffering diabetic foot disease have sever comorbidities, as hypertension, ischemic heart disease, autonomic neuropathy, infections and gastric reflux all of which contribute to a high risk profile for…
- Trial name
- NCT03155568
- Testing
- sciatic nerve block, ankle block, Bupivacaine
- Volunteers
- 90 people
- Sponsor
- Assiut University
Modified Radical Mastectomy
Preemptive Erector Spinae Plane Block Versus Serratus Anterior Plane Block in MRM
Modified radical mastectomy (MRM) is one of the most performed surgeries for breast cancer. MRM is associated with significant pain during the immediate postoperative period.
- Trial name
- NCT06404918
- Testing
- Erector spinae plane group, Serratus anterior plane group
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Benha University
Liposomal Bupivacaine, Postoperative Recovery
A Analgesic Study of Adductor Canal &IPACK Block with Liposomal Bupivacaine in Knee Arthroplasty
To study the effectiveness of ACB and iPACK block with liposomal bupivacaine for postoperative analgesia in patients undergoing knee arthroplasty
- Conditions
- Liposomal Bupivacaine, Postoperative Recovery, Unilateral Knee Arthroplasty
- Trial name
- NCT06145165
- Testing
- Nerve block with ropivacaine and intravenous analgesia, Nerve block with liposomal bupivacaine and intravenous analgesia, Intravenous analgesia
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Postoperative Pain Atskin Graft Site
Comparison of Bupivacaine Versus Bupivacaine-dexamethasone Infiltration for Postoperative Analgesia in Skin Graft Donor Sites
Background: Skin grafting; both partial and complete thickness is frequently used in reconstruction of traumatic soft tissue defects.
- Trial name
- NCT03967392
- Testing
- Xylocaine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Age Problem, Abdominal Cancer
Dosage of Epidural Morphine in Elderly Patients
This a clinical trial that evaluates the efficacy and safety of three different doses of morphine, namely 1.5 mg, 3 mg and 4.5 mg, via the epidural route regarding reducing pain in elderly patients after a cancer surgery in the…
- Trial name
- NCT04316871
- Testing
- 1.5 mg of Morphine Sulfate, Normal saline, 3 mg of Morphine Sulfate
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Assiut University
Postoperative Pain, Mandible Fracture
Postoperative Pain After Bupivacaine Supplementation in Mandibular Fracture Surgery
Pain following open reduction of mandibular fractures is the most reported complaint during the first 24 post-operative hours. The goal of this clinical trial is to evaluate the impact of inferior alveolar nerve block with…
- Conditions
- Postoperative Pain, Mandible Fracture, Analgesia, Anesthesia, Local
- Trial name
- NCT06243263
- Testing
- Bupivacain
- Where
- 2 sites in Tunisia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Bilateral, Ultrasound
Bilateral Ultrasound Guided Intramuscular Quadratus Lumborum Plane Block Versus Bilateral Lateral Quadratus Lumborum Plane Block in Controlling Postoperative Pain in Cancer Patients Undergoing Open Nephrectomy
This study aims to evaluate the efficacy of bilateral ultrasound-guided intramuscular quadratus lumborum plane block (QL4) versus bilateral lateral quadratus lumborum plane block (QL1) in controlling postoperative pain in cancer…
- Conditions
- Bilateral, Ultrasound, Intramuscular Quadratus Lumborum Plane Block, Lateral Quadratus Lumborum Plane Block
- Trial name
- NCT06889987
- Testing
- Intramuscular quadratus lumborum block, Lateral quadratus lumborum block, General anesthesia
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute, Egypt
Pain, Postoperative
Caudal Block With Tramadol and Levobupivacaine or Bupivacaine
Caudal block is the regional anesthetic technique that is used most frequently in pediatric surgery. Opioid drugs have been added to local anesthetic solutions to prolong duration of analgesia but ideal combination were not found…
- Trial name
- NCT01974843
- Testing
- Levobupivacaine, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Duzce University
Pain, Postoperative
TAP Blockade for Pain Control in One-Anastomosis Gastric Bypass
Patients will be randomized into 2 groups: TAP: Patients undergoing TAP blockade, associated with intravenous Acetaminophen analgesia IV: Patients receiving only intravenous Acetaminophen analgesia Postoperative pain 24 hours…
- Trial name
- NCT03775018
- Testing
- Transversus abdominis plane blockade, Intravenous analgesia
- Volunteers
- 140 people
- Sponsor
- Hospital General Universitario Elche
Post Operative Pain
Clavipectoral Block Versus Interscalene Block for Postoperative Analgesia in Midshaft Clavicular Surgery
The aim of this study is to compare between (ISBPB) and (CPB) as postoperative analgesic technique following midshaft clavicular fracture open reduction and internal fixation surgeries.
- Trial name
- NCT06917820
- Testing
- Interscalene brachial plexus block, Clavipectoral fascia plane block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Paediatric, Surgery
Erector Spinae Plane Block for Paediatric Upper Abdominal Surgery
Upper abdominal surgeries are associated with severe postoperative pain. Thus, maintaining effective postoperative analgesia in the paediatric age group is very crucial in terms of future pain perception and chronic pain…
- Conditions
- Paediatric, Surgery, Analgesia, Anesthesia
- Trial name
- NCT04518215
- Testing
- Erector Spinae Plain Block, Intra-Venous Analgesia
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Nazmy Edward Seif
Postoperative Pain Management, Laparoscopic Hysterectomy
Intrathecal Morphine Versus Trocar-Site and Intraperitoneal Bupivacaine for Quality of Recovery After Laparoscopic Hysterectomy
This study aims to compare the effects of intrathecal morphine with trocar-site infiltration and intraperitoneal bupivacaine on postoperative pain control, quality of recovery, and inflammatory response in patients undergoing…
- Conditions
- Postoperative Pain Management, Laparoscopic Hysterectomy, Postoperative Recovery
- Trial name
- ITM-LH-QoR (NCT07232108)
- Testing
- Intrathecal Morphine, Trocar-Site Bupivacaine Infiltration, Intraperitoneal Bupivacaine spray
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Ataturk University
Spinal Anesthesia, Analgesia
Femoral Nerve Block vs Peri-capsular Nerve Group Block for Hip Fracture Analgesia
The purpose of the study is to compare the analgesic efficacy of femoral nerve block and peri-capsular nerve group block administered before spinal anesthesia for positioning to spinal anaesthesia in patients undergoing surgery…
- Conditions
- Spinal Anesthesia, Analgesia, Hip Fractures
- Trial name
- NCT05444803
- Testing
- femoral nerve block, peri-capsular nerve group block
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Antalya Training and Research Hospital
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