Clinical trials: Bupivacaine
Postoperative Pain
Analgesia iv vs Epidural Analgesia vs Port-sites Infiltration After Laparoscopic Sleeve Gastrectomy
A prospective randomized study of patients undergoing laparoscopic sleeve gastrectomy between 2012 and 2015 will be performed. Patients will be divided into 3 groups: Analgesia iv exclusively (Group 1), epidural…
- Trial name
- NCT02662660
- Testing
- Port-sites infiltration:Bupivacaine0.25%, Epidural analgesia:Levobupivacaine0,125%, Metamizole and Acetaminophen iv
- Volunteers
- 147 people
- Sponsor
- Hospital General Universitario Elche
Postoperative Pain, Acute
Combined Ketorolac Bupivacaine Versus Bupivacaine Alone for TAP Block in Children Undergoing Lower Abdominal Surgeries
Control of of pain in children is fundamental. TAP block is associated with less side effects compared with other neuraxial techniques especially when done under ultrasound guidance.
- Trial name
- NCT06267820
- Testing
- Bupivacain, Ketorolac
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Sohag University
Chemical Rectus Sheath Block, Chronic Pain
Ultrasound Guided- Chemical Rectus Sheath Block for Chronic Pain After Abdominal Midline Incision in Cancer Surgeries
The aim of this study is to evaluate peri-operative analgesia efficacy of ultrasound guided transversalis fascia plane block in cancer patients undergoing inguinal lymph node dissection
- Conditions
- Chemical Rectus Sheath Block, Chronic Pain, Abdominal Midline Incision, Cancer Surgeries
- Trial name
- NCT07855380
- Testing
- Saline 0.9%, Transversalis fascia plane block
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute, Egypt
Cleft Palate Children, Block
Suprazygomatic Nerve Block vs Surgical Site Infiltration in Cleft Palate Repair
The aim of this study is to evaluate the efficacy and duration of effect of bupivacaine given preoperatively as a bilateral suprazygomatic maxillary nerve block and to compare it with peri-incisional infiltration with the same…
- Trial name
- NCT03799068
- Testing
- suprazygomatic maxillary nerve block, surgical site infiltration
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Glaucoma
Dexmedetomidine as an Additive to Local Anaesthesia to Decrease Intraocular Pressure in Glaucoma Surgery
Nowadays, a number of cases with increased intraocular pressure and glaucoma have been shown a huge increase . This is because of the increase the geriatric population in the community and advanced medical care.
- Trial name
- NCT02846090
- Testing
- Dexmedetomidine to reduce the IOP
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Cairo University
Pain, Postoperative
Pudendal Nerve Block for Post-Episiotomy Pain Relief
Unilateral vs. Bilateral Pudendal Nerve Block for Post-Episiotomy Pain Relief: A Randomized Clinical Trial
- Trial name
- NCT03944291
- Testing
- Pudendal Nerve Block
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Ain Shams University
Postoperative Pain, Acute, Lung Cancer
Thoracic Surgery Intercostal Block Trial With Liposomal vs. Hydrochloride Bupivacaine
This randomized controlled trial evaluates the analgesic effects of liposomal bupivacaine compared to bupivacaine hydrochloride in intercostal nerve block for patients undergoing thoracoscopic lung surgery.
- Trial name
- NCT07134660
- Testing
- Liposomal Bupivacaine intercostal nerve block, Bupivacaine Hydrochloride intercostal nerve block, Standard Postoperative Analgesia
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Abdominal Cancer
Efficacy of Transverses Abdominis -Plane Block With Bupivacaine Versus Bupivacaine With Morphine Postoperatively
This study aims to compare the analgesic efficacy of transversus abdominis-plane block with bupivicaine versus bupivacaine with morphine in patients undergoing major abdominal cancer surgery.
- Trial name
- NCT02566096
- Testing
- transversus abdominis-plane block with local anesthetic 20 ml of bupivacaine 0.5% + 10 mg morphine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Aortic Valve Stenosis, Aortic Diseases
PENG Block forTranscatheter Aortic Valve Implantation
Pericapsular nerve group (PENG block) is a new fascial block defined by Arango et al. This block aims to block the femoral nerve and the accessory obturator nerve by injecting local anesthetic between the pubic ramus and psoas…
- Trial name
- NCT05904912
- Testing
- Postoperative analgesia management, PENG-Bupivacaine, Local infiltration-Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Medipol University
Postoperative Pain
Comparison of Transversus Abdominis Plane Block and Erector Spinae Plane Block in Inguinal Hernia Repair
Multimodal analgesia is used to control postoperative pain in inguinal hernia repair. Transversus abdominis plane block is an effective regional anesthesia technique for postoperative analgesia in inguinal hernia repairs.
- Trial name
- NCT03515434
- Testing
- ESP Block, TAP Block, Standard Pain Followup and Monitorization
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Maltepe University
Breast Neoplasm Female, Analgesics
U/S Guided Rhomboid Intercostal Block Combined With Sub-Serratus Plane Block vs Type 2 Pectoral Nerve Block
The aim of this study is to compare between U/S Guided Rhomboid Intercostal Block Combined with Sub-Serratus Plane Block vs type 2 Pectoral Nerve Block in Analgesia for Breast Cancer Surgery by measuring intraoperative…
- Trial name
- NCT06274814
- Testing
- U/S guided Type 2 Pectoral Nerve Block, U/S guided RIB combined with the sub-serratus plane block (RISS)
- Where
- Egypt
- Volunteers
- 69 people
- Sponsor
- National Cancer Institute, Egypt
Postoperative Pain
US-Guided Quadro-Iliac Plane Block for Postoperative Analgesia After Lumbar Instrumentation
Lumbar instrumentation surgery is associated with significant postoperative pain. This study evaluates the analgesic effectiveness of the ultrasound-guided Quadro-Iliac Plane Block in patients undergoing lumbar instrumentation…
- Trial name
- QIPB (NCT07370428)
- Testing
- Quadro-Iliac Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bursa City Hospital
Post Operative Pain
Addition of MgSO4 or Dexamethasone to Bupivacaine on the Prolongation of Ultrasound-guided Quadratus Lumboram Block
The goal of postoperative pain management is the provision of comfort, early mobilization and improved respiratory function without causing inadequate sedation and respiratory compromise, which can be achieved through using…
- Trial name
- NCT05397236
- Testing
- Bupivacaine- Magnesium, Bupivacaine dexamethasone, Bupivacaine saline
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Ain Shams University
Postoperative Pain
Efficacy of Erector Spinae Plane Block in Caridac Surgery
Introduction: Opioid-based pharmacological treatment is frequently used in the treatment of pain after coronary artery bypass graft (CABG) surgery.
- Trial name
- NCT05312957
- Testing
- erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Postoperative Pain
Phase 2 Herniorrhaphy Study for Opioid Elimination
This is a Phase 2, open-label study in subjects undergoing unilateral open inguinal herniorrhaphy.
- Trial name
- NCT03695367
- Testing
- HTX-011, Luer lock applicator, Vial access device
- Where
- 5 sites in United States
- Volunteers
- 63 people
- Sponsor
- Heron Therapeutics
Opioid Use
Impact of Bilateral Deep Parasternal Intercostal Plane Block on Intraoperative Opioid Consumption in Open Heart Surgery
This study aims to assess the impact of bilateral deep parasternal intercostal plane block on intraoperative opioid consumption in open heart surgery
- Trial name
- NCT05103787
- Testing
- deep parasternal intercostal plane block, control
- Where
- 2 sites in Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Cervical Spine Surgery
Analgesic Efficacy of the Novel Intra- Semispinal Fascial Plane Block in Posterior Cervical Spine Surgery
Posterior cervical spine surgery often requires a large posterior midline incision, resulting in poorly controlled postoperative pain, which arises from iatrogenic mechanical damage, intraoperative retraction, and resection to…
- Trial name
- NCT04974658
- Testing
- Inter-semispinal plane block
- Where
- 2 sites in Egypt
- Volunteers
- 52 people
- Sponsor
- Zagazig University
Acute Pain
Liposomal Bupivacaine Interscalene Blocks for Rotator Cuff Repair
The purpose of this study is to compare pain control after arthroscopic rotator cuff repair surgery using either liposomal bupivacaine or bupivacaine when injected in an interscalene block.
- Trial name
- RCR (NCT03587584)
- Testing
- liposomal bupivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Minnesota
Upper Extremity Problem
The Comparation of Lateral Sagittal Infraclavicular and Costoclavicular Block
In this study, the investigators aimed to compare the block dynamics and characteristics of the two approaches while providing effective analgesia and safe anesthesia of the Ultrasound-guided Lateral sagittal Infraclavicular and…
- Trial name
- NCT04921852
- Testing
- costoclavicular brachial plexus block, lateral sagittal infraclavicular block
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Neuromuscular Block
Dexmetomidine Intrathecally and Intravenously Additionally to Spinal Anaesthesia, in Total Knee Arthroplasty
The present study is designed to evaluate and compare the efficacy of intrathecal dexmedetomidine (DEX) as an adjuvant to Levobupivacaine in spinal anaesthesia and DEX's intravenous administration, without loading dose…
- Trial name
- NCT02966249
- Testing
- Levobupivacaine, Dexmetomidine intravenously, Normal Saline added intrathecally
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- KAT General Hospital
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