Clinical trials: Bupivacaine
Pain, Neuropathic
Can Dexmedetomidine With Hyalase Augment Quality and Duration of Analgesia When Added to Lumbar Epidural Steroid in Failed Back Surgery. Randomized Double Blind Study
use of dexmedtemodine to augment analgesia in cases of failed back surgery
- Trial name
- NCT05349448
- Testing
- Hylase plus Triamcinolone plus sterile isotonic saline, Hylase plus Dexmedetomidine plus Triamcinolone
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Minia University
Analgesia, Patient-Controlled, Epidural Analgesia
Intrathecal Morphine Analgesia vs. Continuous Epidural Analgesia vs. Systemic Analgesia in Colorectal Surgery.
The purpose of this study is to determine which postoperative analgesia is optimal after colorectal surgery. The investigators will compare intrathecal morphine, continuous epidural analgesia and standard systemic analgesia.
- Conditions
- Analgesia, Patient-Controlled, Epidural Analgesia, Anesthesia; Spinal, Morphine
- Trial name
- KOLORIT (NCT03007121)
- Testing
- Morphine intrathecal, Bupivacaine + Sufentanil epidural, Morphine intravenous
- Where
- Czechia
- Volunteers
- 75 people
- Sponsor
- Charles University, Czech Republic
Rheumatoid Arthritis
Nerve Block of the Proximal Interphalangeal Joints PIPs in Rheumatoid Arthritis (RA) Patients: a Prospective Pilot Study
Researchers will include 83 rheumatoid arthritis patients (either early or established) diagnosed after 2010 ACR/EULAR criteria with bilateral hand arthritis aged 18 or above.
- Trial name
- NCT04130178
- Testing
- Nerve block, Saline injection
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Sohag University
Arthroscopy, Analgesia
Ultrasound-Guided Extrafascial Versus Intrafascial Interscalene Brachial Plexus Block in Shoulder Arthroscopy
The aim of the study is to compare the diaphragmatic excursion and postoperative analgesia in the extrafascial versus intrafascial Interscalene brachial plexus block in patients undergoing shoulder arthroscopy.
- Conditions
- Arthroscopy, Analgesia, Intrafascial Interscalene Brachial Plexus Block
- Trial name
- NCT05222334
- Testing
- Intrafascial interscalene brachial plexus block, Extrafascial interscalene brachial plexus block group, Bupivacaine
- Volunteers
- 50 people
- Sponsor
- Tanta University
Pain, Postoperative
Interscalene Catheter vs. Interscalene Liposomal Bupivacaine for Arthroscopic Rotator Cuff Repair
Arthroscopic rotator cuff repair often causes significant postoperative pain. An interscalene nerve catheter is an effective and proven method to help reduce postoperative pain and decrease opioid use around the time of shoulder…
- Trial name
- NCT04571606
- Testing
- Single injection peripheral nerve block with liposomal bupivacaine (Exparel), Single injection peripheral nerve block with 0.25% bupivacaine and subsequent peripheral nerve catheter with 0.2% bupivacaine infusion via onQ pain pump
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of North Carolina, Chapel Hill
Osteoarthritis
Adductor Canal Block Versus Periarticular Bupivicaine Injection in Total Knee Arthroplasty
The objective of the study is to compare the efficacy of adductor canal blocks versus periarticular bupivacaine injections for pain management in total knee arthroplasty.
- Trial name
- NCT02777749
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 155 people
- Sponsor
- Columbia University
Post Operative Pain in Total Abdominal Hystrectomy
Comparison Between Tranversus Abdominis Plane (TAP) Block With Only Bupivacaine and TAP Block With Bupivacaine Plus Ketamine in Reducing Postoperative Pain After Total Abdominal Hystrectomy
The goal of this study is to know how effectively TAP block can reduce postoperative pain in total abdominal hystrectomy patients when given ketamine in addition to bupivacaine in TAP block and to compare it with the conventional…
- Trial name
- TAP-BvsBK-TAH (NCT07482709)
- Testing
- bupivicaine 0.25%, bupivicaine 0.25% + ketamine
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Liaquat National Hospital & Medical College
Post-Op Complication
Comparison of Intrathecal Dexmedetomidine Versus Fentanyl as Adjuvants to Bupivacaine on Post-operative Urinary Retention in Knee Joint Arthroscopic Surgeries
The aim of this study was to assess the effect of intrathecally injected 5 µg dexmedetomidine or 25 µg fentanyl as adjuvants to bupivacaine in low dose spinal anesthesia for unilateral arthroscopic knee surgeries, on…
- Trial name
- NCT05596552
- Testing
- hyperbaric bupivacaine and dexmedetomidine, Bupivacaine-Fentanyl group
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Anesthesia
Dexmedetomidine Added to Bupivacaine Versus Bupivacaine inTransincisionalU/S Guided Quadratus Lumborum Block in Open Renal Surgeries , A New Technique
The purpose of this study is to compare the addition of dexmedetomidine to bupivacaine versus bupivacaine only in anterior QLblock(transincisional) , where the local anesthetic will be applied before wound closure at the end of…
- Trial name
- NCT03869047
- Testing
- Dexmedetomidine +bupivacaine, Bupivacaine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Anesthesia, Local, Shoulder Surgery
The Effect of Dexamethasone on the Duration of Interscalene Nerve Blocks With Ropivacaine or Bupivacaine
This study will test the hypothesis that adding dexamethasone significantly prolongs the duration of ropivacaine and bupivacaine analgesia, and that the magnitude of the effect differs among the two local anaesthetics..
- Trial name
- NCT00801138
- Testing
- saline, Dexamethasone, ropivacaine
- Where
- United States
- Volunteers
- 218 people
- Sponsor
- The Cleveland Clinic
Acute Herpes Zoster Pain Managment
Ultrasound-Guided Erectro Spinae Plane Block Versus Stellate Ganglion Block for Patients With Upper Limb Acute Herpes Zoster Pain.
Herpes zoster (HZ) is a painful, eruptive, viral condition results from reactivation of the latent varicella zoster virus after the primary infection.
- Trial name
- NCT06307444
- Testing
- Ultrasound-Guided Stellate Ganglion Block, T2 T3 (High Thorathic) ESP Block
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Tanta University
Post Operative Pain as Estimated by the Sue of the VAS Score
Ilioinguinal Block in Laparoscopic Inguinal Hernia Repair
This study is undertaken to clarify whether intraoperative blockage with 40 ml of ½ % Marcaine© of the nerves in the ilio-inguinal canal may decrease postoperative pain after laparoscopic inguinal hernia repair.
- Trial name
- NCT01969006
- Testing
- Marcaine ½%, Needle prick
- Where
- 2 sites in Denmark
- Sponsor
- Randers Regional Hospital
Motor Impairments, Orthopaedic Injuries
Gait Characteristics Following a Fall
The purpose of this study is to quantify the safety degree of the patient's gait, to detect the reason for the fall and quantify the biomechanical parameters related to fall.
- Conditions
- Motor Impairments, Orthopaedic Injuries, Neurological Conditions
- Trial name
- NCT01631604
- Testing
- Walking aids and devices, Muscle/nerve injection, Corrective surgery
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Postoperative Pain
EXPAREL Administered Into the TAP for Analgesia in Subjects Undergoing Open Total Abdominal Hysterectomy
The primary objective of this study is to determine the optimal of two different volumes of EXPAREL 266 mg when administered via infiltration into the transversus abdominis plane (TAP) for prolonged postoperative analgesia in…
- Trial name
- NCT01919606
- Testing
- EXPAREL
- Volunteers
- 1 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Osteoarthritis, Hip, Osteoarthritis, Knee
Spinal Anaesthesia vs. General Anaesthesia for THA, TKA and UKA
The goal of this randomized clinical trial is to investigate the postoperative recovery following hip and knee arthroplasty procedures depending on the use of either spinal anaesthesia (SA) or general anaesthesia (GA).
- Trial name
- RCT SAGA (NCT05706844)
- Testing
- Spinal anesthesia, General anaesthesia
- Where
- 2 sites in Denmark
- Volunteers
- 222 people
- Sponsor
- Anders Troelsen
Postoperative Analgesia, Anesthesia; Functional
Comparison of Two Regional Technics In Knee Artroplasty
Purpose: This prospective, randomised, controlled, single-blind, multicentre study was designed to investigate the effects of peripheral nerve block methods (applied using unilateral spinal anaesthesia [USA] on elderly patients…
- Trial name
- CTRTIKA (NCT03021421)
- Testing
- intratechal (subarachnoidal )injection, lombar plexus and sciatic nerve injection
- Volunteers
- 60 people
- Sponsor
- Ordu University
Hip Fractures, Peripheral Nerve Block
Pericapsular Nerve Block and Iliopsoas Fascial Plane Block in Hip Surgery
This prospective randomized interventional study aims to compare the effects of two peripheral nerve blocks, the periencapsular nerve block (PENG) and iliopsoas block (IPB), on analgesia and motor function after hip surgery.
- Trial name
- NCT06267716
- Testing
- PENG block, IPB
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Haseki Training and Research Hospital
Pain, Postoperative, Developmental Dysplasia of the Hip
Intravenous Dexamethasone to Prolong Caudal Block Analgesia in Children Undergoing Hip Surgery
The goal of this clinical trial is to learn whether a single intravenous dose of dexamethasone prolongs postoperative analgesia after a caudal block in children aged 6 months to 9 years undergoing surgery for developmental…
- Trial name
- DEXA-CAUDAL (NCT07896304)
- Testing
- Dexamethasone, Normal Saline, Caudal Block Anesthesia
- Where
- Tunisia
- Volunteers
- 54 people
- Sponsor
- National Institute of Neurology, Tunisia
Upper Extremity Injury
Single Versus Double Injection Costoclavicular Block
In this trial, the objective is to compare single- and double-injection ultrasound-guided costoclavicular blocks. The rationale behind this idea is that a second local anesthetic injection, inside the costoclavicular space, may…
- Trial name
- NCT03595514
- Testing
- Single injection, Double injection, lidocaine, bupivacaine, epinephrine, dexamethasone
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Analgesics, Opioid, Anesthesia, Spinal
Comparing the Safety and Effectiveness of Different Doses of Morphine Administered in Spinal Anethesia for Pain Relief After Hip Replacement Surgery
Pain management after total hip replacement is one of the most important aspects of postoperative care for patients and clinicians alike.
- Conditions
- Analgesics, Opioid, Anesthesia, Spinal, Total Hip Replacement, Adverse Anesthesia Outcome
- Trial name
- NCT06878014
- Testing
- Spinal Anesthesia (bupivacaine), Postoperative pain management with acetaminophen, PCA IV Oxycodone
- Where
- 3 sites in Poland
- Volunteers
- 120 people
- Sponsor
- Medical University of Silesia
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