Clinical trials: Bupivacaine
Labor Pain
Intrathecal Analgesia for Normal Labour
Primary outcome: Compare the duration of analgesia. Secondary outcome: analgesic potency of bupivacaine and fentanyl versus levobupivacaine and fentanyl.
- Trial name
- NCT04221568
- Testing
- Bupivacaine-fentanyl, levobupivacaine-fentanyl
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pregnancy
PIEB vs CEI for Labor Analgesia: An MLAC Study
Utilizing a 'minimal local analgesic concentration (MLAC) study' design to first determine the relative potency of Programmed Intermittent Epidural Bolus (PIEB) compared to Continuous Epidural Infusion (CEI) and secondly to…
- Trial name
- NCT02573597
- Testing
- Bupivacaine, Sufentanil
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Stanford University
Pain, Postoperative, Breast Surgery
One-level and Bi-level ESPB Application in Patients Undergoing Breast Surgery
Acute pain after breast surgery can significantly reduce the quality of life for patients. If acute pain is not adequately treated, it can develop into chronic pain.
- Conditions
- Pain, Postoperative, Breast Surgery, Erector Spinae Plane Block, Multimodal Analgesia
- Trial name
- NCT07747623
- Testing
- One-level Erector Spinae Plane Block, Bi-level Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Adductor Magnus Plain Injection for Sciatic Nerve Block
Using the Adductor Magnus Plain Block as an Innovative Approach for Sciatic Nerve Block for Lower Limb Surgeries.
the goal of this clinical trial is to compare the efficacy of adductor magnus muscle plane injection as an approach for sciatic nerve block to sub-gluteal approach in combination with femoral nerve blocks as perioperative…
- Trial name
- NCT06852118
- Testing
- AMM Group: Adductor Magnus Muscle Plane approach + Femoral Nerve Blocks, SG Group: Sciatic nerve block by sub-gluteal approach + Femoral nerve blocks
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mohammed Gaber Saad
Postoperative Analgesia in Patients Undergoing Open Renal Surgery
Ultrasound-Guided Midpoint Transverse Process to Pleura Block Versus Erector Spinae Plane Block for Postoperative Analgesia in Patients Undergoing Open Renal Surgery :A Randomized Comparative Study.
The goal of this randomized comparative clinical trial is to compare the analgesic effectiveness of ultrasound-guided Midpoint Transverse Process to Pleura (MTP) block versus Erector Spinae Plane (ESP) block in adult patients…
- Trial name
- NCT07881523
- Testing
- Midpoint Transverse Process to Pleura (MTP)Block, Erector spinae plane (ESP) block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Minia University
Hip Fracture
Comparison of Intraoperative- Postoperative Effects of Pericapsular Nerve Block and Fascia Iliaca Block in Hip Fracture
The aim of this study is to apply pericapsular nerve group (PENG) block or fascia iliaca plan block using ultrasonography to patients who will undergo hip fracture surgery, while giving sitting position before spinal anaesthesia…
- Trial name
- NCT06001996
- Testing
- Pericapsular nerve group (PENG) block, Suprainguinal fascia iliaca plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Post-operative Pain, Thoracic Epidural
Dexmedetomidine and Fentanyl as Adjuvants to Thoracic Epidural
To find out if there is a benefit from adding dexmedetomidine to epidural bupivacaine as regards: Intra and postoperative opioid consumption Pain score (numerical rating scale) Hemodynamic stability, Patient satisfaction.
- Conditions
- Post-operative Pain, Thoracic Epidural, Thoracotomy Surgery
- Trial name
- adjuvants (NCT06489574)
- Testing
- thoracic epidural with dexmedetomidine in patients undergoing thoracotomy surgery, thoracic epidural with fentanyl in patients undergoing thoracotomy surgery
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain
Local Continuous Wound Infusion of Anesthetics in the Management of Post-operative Pain After Total Hip Arthroplasty.
The combination of subarachnoid anaesthesia (SAB) and continuous local wound infiltration (LCWI) with a consistent amount of local anaesthetics could prevent central sensitization through an additive or synergistic effect because…
- Trial name
- NCT02728310
- Testing
- Levobupivacaine, Saline
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- San Salvatore Hospital of L'Aquila
Pain,Postoperative
Modified Thoracoabdominal Nerve Block(M-TAPA) in Total Laparoscopic Hysterectomies
The aim of the study is comparing the postoperative effects of ultrasound-guided Modified Perichondrial Approach to Thoracoabdominal Nerves (M-TAPA) block for postoperative pain control after total laparoscopic hysterectomy.
- Trial name
- NCT06601413
- Testing
- M-TAPA Block, Trocar site local anesthetic infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Gulhane Training and Research Hospital
Laparoscopic Cholecystectomy
ERAS (Enhanced Recovery After Surgery) and Multimodal Analgesia in Laparoscopic Cholecystectomy
This clinical study aims to evaluate the effects of multimodal analgesia management administered within an ERAS (Enhanced Recovery After Surgery) protocol on postoperative pain, length of hospital stay, early complications, and…
- Trial name
- ERAS (NCT06885086)
- Testing
- Control group - 1, Observation group -2
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Migraine Headache
Greater Occipital Nerve Block for Migraine Prophylaxis
Migraine is a common neurological condition that can be disabling, particularly if chronic. Greater occipital nerve (GON) block has been utilized for decades for the treatment of migraine in the absence of a single randomized…
- Trial name
- NCT00915473
- Testing
- bupivicaine, normal saline, methylprednisolone
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Mayo Clinic
Pain, Postoperative
Efficacy of Dexmedetomidine as an Adjuvant to Quadratus Lumborum Block
This prospective double blinded study will be conducted over 60 pediatric patients ASA (American Association of Anesthesiologists) I and II between the age of 1-7 years old, who will be scheduled for unilateral groin surgery.
- Trial name
- NCT05979376
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Opioid Consumption, Postoperative Pain
Effect of ESPB and Rhomboid Block on VATS Method
The aim of this study is to compare ultrasound-guided ESBP and Rhomboid block in terms of postoperative pain management, postoperative opioid consumption and complications in patients undergoing lobectomy with VATS.Patients aged…
- Conditions
- Opioid Consumption, Postoperative Pain, Complication,Postoperative
- Trial name
- NCT05618210
- Testing
- regional anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Marmara University
Lumbar Radiculopathy, Lumbar Disc Herniation
Randomized Evaluation of Lumbar Injection Effectiveness and Function
The goal of this clinical trial is to learn whether the Triojection® System is safe and effective for treating symptomatic lumbar radiculopathy (leg pain caused by nerve irritation or compression) resulting from a contained…
- Conditions
- Lumbar Radiculopathy, Lumbar Disc Herniation, Contained Herniated Lumbar Disc
- Trial name
- RELIEF (NCT07856810)
- Testing
- Triojection® System, Selective Nerve Root Block (SNRB)
- Volunteers
- 300 people
- Sponsor
- SpinaFX Medical Inc.
Preeclampsia
Adding MgSO4 to Epidural Levobupivacaine in CS for Patients With Preeclampsia
This study aims at evaluating the effect of adding magnesium sulphate epidurally as an adjunct to levobupivacaine on the quality of anesthesia and perioperative pain relief in patients with preeclampsia undergoing elective…
- Trial name
- NCT02699827
- Testing
- Levobupivacaine hydrochloride, Magnesium sulphate, Saline 0.9%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mohamed Sayed Abdelhafez
Benign Prostatic Hypertrophy
The Effects of Intrathecal Dexmedetomidine on Spinal Anesthesia Using Diluted Low-Dose Bupivacaine for Transurethral Resection of Prostate in Elderly
Spinal block is the most common anesthetic technique for transurethral resection of prostatectomy (TURP). Most patients undergoing TURP are elderly and frequently present with cardiopulmonary and endocrine diseases.
- Trial name
- NCT01342562
- Testing
- spinal anesthesia
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Yonsei University
Shoulder Arthroscopy, Postoperative Analgesia
Erector Spinae Plane Block Versus Intraarticular Injection for Postoperative Analgesia in Shoulder Arthroscopy
To improve the outcome after surgery, effective pain control is needed. The aim of the current study was to compare the efficacy of ultrasound guided erector spinae plane block versus the intra articular injection of local…
- Conditions
- Shoulder Arthroscopy, Postoperative Analgesia, Erector Spinae Plane Block, Intraarticular Injection
- Trial name
- NCT04483323
- Testing
- Erector Spinae Plane Block, Intraarticular Injection
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Anesthesia, Local
Comparison of US-guided Single-dose Thoracic Paravertebral, Erector Spinae Plane and Serratus Anterior Plane Blocks
This study evaluates the analgesic effects of ultrasound-guided regional techniques, Thoracic Paravertebral Block (TPVB), Erector Spinae Plane Block (ESPB) and Serratus Anterior Plane Block(SAPB) by comparing postoperative total…
- Trial name
- NCT05431062
- Testing
- Bupivacain
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Chronic Low Back Pain
Epidural Study of Patients With Chronic Lower Back Pain
The purpose of this study is to examine 4 different epidural dosing regimes of local anaesthetic solution in a series of 3 epidural injections over a period of 12 months to determine the optimum dose of anaesthetic solution for…
- Trial name
- NCT00887003
- Testing
- Bupivacaine, Depo-Medrol
- Where
- Canada
- Volunteers
- 252 people
- Sponsor
- McMaster University
Cardiac Pacing, Permanent Pacemaker Implantation
Ultrasound-Guided PECS II Block for Permanent Pacemaker Implantation
This single-center, prospective, randomized, controlled clinical trial aims to evaluate whether ultrasound-guided PECS II block, when added to standard local infiltration anesthesia, improves perioperative analgesia in patients…
- Conditions
- Cardiac Pacing, Permanent Pacemaker Implantation, Postoperative Pain
- Trial name
- PACE-PECS (NCT07739407)
- Testing
- Ultrasound-Guided PECS II Block, Standard Local Infiltration Anesthesia
- Volunteers
- 72 people
- Sponsor
- ferdi gülaştı
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