Clinical trials: CPAP
Sleep-disordered Breathing, Hypercapnia
Physiological Study to Compare Noninvasive Ventilation (NIV) Masks
Noninvasive ventilation (NIV) is an established therapy that delivers positive pressure to the upper airways to provide respiratory support.
- Trial name
- NCT04926805
- Testing
- CPAP with Mask A, CPAP with Mask B
- Where
- New Zealand
- Volunteers
- 40 people
- Sponsor
- Fisher and Paykel Healthcare
Covid19, Obstructive Sleep Apnea
Early Application of Continuous Positive Airway Pressure in Coronavirus Patients at Risk of Obstructive Sleep Apnea
This was an experimental clinical trial, Aim: To evaluate the role of early use of Continuous Positive Airway Pressure (CPAP) in management of moderate to severe Coronavirus disease 2019 patients at risk of Obstructive Sleep…
- Conditions
- Covid19, Obstructive Sleep Apnea, CPAP Ventilation, Corona Virus Infection
- Trial name
- NCT05934916
- Testing
- CPAP ( Continuous positive airway pressure), oxygen therapy
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
The Screening and the Treatment of ECG Holter and Sleep Apnea
The Screening and the Treatment of ECG Holter and Sleep Apnea
Sleep quality affect working and learning performance; poor quality of sleep is one of the common problems of modern people. Traditionally, polysomnography is a recognized standard for sleep quality assessment.
- Trial name
- NCT05928923
- Testing
- CPAP
- Where
- Taiwan
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
COVID-19, COVID-19 Acute Respiratory Distress Syndrome
The Effect of Listening to Music During CPAP on the Agitation Levels and Compliance.
Aim: This study was conducted to determine the effect of listening to music during CPAP on the agitation levels of intensive care patients who underwent CPAP due to COVID-19 and their compliance with the treatment.
- Trial name
- NCT05102084
- Testing
- Listening to music with a bluetooth headset to patients receiving CPAP support
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- SÜMEYYE BİLGİLİ
Obstructive Sleep Apnea
Improving 24-hour Blood Pressure in Obstructive Sleep Apnea
This study examines the combined effects of an angiotensin receptor blocker (ARB), antioxidant supplementation, and continuous positive airway pressure (CPAP) therapy on the lowering of 24-hour blood pressure in persons with…
- Trial name
- NCT04021550
- Testing
- Continuous Positive Airway Pressure CPAP, Telmisartan 80mg, Alpha-Lipoic Acid 600mg
- Sponsor
- University of British Columbia
Acute on Chronic Hypercapnic Respiratory Failure, Obesity Hypoventilation Syndrome (OHS)
"Post-acute Pickwick Study" (Postacute-Pick-2020)
We propose to carry out a large multicentric, multinational, randomized controlled trial with two phases (two sequential randomized controled trials) to answer two questions: 1) Should hospitalized patients with recently…
- Trial name
- NCT04317326
- Testing
- "Lifestyle modifications" group (Control), Automatic NIV, CPAP treatment group
- Sponsor
- Juan F. Masa
Obstructive Sleep Apnea
Domiciliary Transcutaneous Electrical Stimulation in Obstructive Sleep Apnoea
The aim of this study is to assess the efficacy of transcutaneous electrical stimulation of the pharyngeal dilator muscles in patients with obstructive sleep apnoea in the community compared to usual care, and follow the patients…
- Trial name
- TESLA-home (NCT03160456)
- Testing
- Transcutaneous electrical stimulation, Continuous positive airway pressure
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Sleep-disordered Breathing, Major Depressive Disorder
Sleep-Disordered Breathing and PAP in Perinatal Depression
The goal of this study is to understand the contribution of sleep-disordered breathing (SDB) to one of the most common and debilitating adverse pregnancy outcomes, perinatal depression.
- Trial name
- NCT02507297
- Testing
- Positive Airway Pressure (PAP)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Michigan
Respiratory Insufficiency Syndrome of Newborn
CPAP vs NIPPV: A COMPARATIVE EFFECTIVENESS RESEARCH
Aim: Investigators aim is to conduct two complementary and concurrent CER projects using a pragmatic clinical trial design and registry-based RWD to identify the optimal respiratory management practices for extremely preterm…
- Trial name
- NCT04075123
- Testing
- CPAP
- Where
- Canada
- Volunteers
- 1,829 people
- Sponsor
- Canadian Neonatal Network
Obstructive Sleep Apnea Syndrome, Gut Microbiota
Intestinal Dysbiosis During Obstructive Sleep Apnea Syndrome
Obstructive Sleep Apnea Syndrome (OSA) is one of the most common chronic diseases and is associated with prognostic cardiovascular and metabolic co-morbidities.
- Trial name
- DYNAMIC (NCT04947410)
- Testing
- CPAP or nasal dilators
- Sponsor
- University Hospital, Grenoble
Mild Cognitive Impairment, Sleep Apnea, Obstructive
MCI: CPAP Treatment of OSA (Memories2)
The purpose of this project is to determine whether obstructive sleep apnea (OSA) treatment with positive airway pressure therapy (CPAP) can delay the progression of cognitive impairment in patients with amnestic Mild Cognitive…
- Trial name
- MCI:OSA (NCT03113461)
- Testing
- CPAP
- Where
- 4 sites in United States
- Volunteers
- 327 people
- Sponsor
- University of Pennsylvania
Obese, Pregnancy
Sleep Disordered Breathing, Obesity and Pregnancy Study (SOAP)
The purpose of this study is to better understand how sleep apnea, a common sleep disorder in which a person has one or more pauses in breathing or shallow breaths while sleeping, may affect pregnancy and to determine the effect…
- Conditions
- Obese, Pregnancy, Sleep Disordered Breathing
- Trial name
- SOAP (NCT02086448)
- Testing
- CPAP, Sleep hygiene
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- Francesca Facco, MD
Polycystic Ovary Syndrome, Obstructive Sleep Apnea
Polycystic Ovary Syndrome (PCOS) and Sleep Apnea
Polycystic ovary syndrome (PCOS) affects 5-10% of women in the United States. Its onset is usually at the time of puberty with manifestations of menstrual irregularity, hirsutism, and obesity.
- Trial name
- NCT00203996
- Testing
- continuous positive airway pressure (CPAP), depot leuprolide plus estrogen/progestin replacement, pioglitazone
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Pneumonia, Respiratory Failure
CPAP Versus HFNO for the Treatment of Acute Hypoxemic Respiratory Failure Due to Community Acquired Pneumonia
the study compares two non-invasive respiratory support modalities ie CPAP and High Flow nasal cannula oxygen for the treatment of severe hypoxemic respiratory failure attributed to Community acquired Pneumonia.
- Trial name
- NCT05755425
- Testing
- CPAP, HFNO
- Where
- 2 sites in Greece
- Volunteers
- 100 people
- Sponsor
- Evangelismos Hospital
Sleep Apnea, Chronic Pain Syndrome
Sleep and Pain Sensitivity
This project will assess patients with diagnosed obstructive sleep apnea, to investigate the impact of poor sleep on central pain mechanisms.
- Trial name
- NCT04246294
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- Denmark
- Volunteers
- 6 people
- Sponsor
- Aalborg University
Respiratory Distress Syndrome, Newborn, Infant, Newborn
Feasibility of Uninterrupted Infant Respiratory Support Treatment
Feasibility study of a simplified respiratory support system for newborn infants
- Conditions
- Respiratory Distress Syndrome, Newborn, Infant, Newborn, Respiratory Insufficiency Syndrome of Newborn
- Trial name
- FUIRST (NCT04244890)
- Testing
- Uninterrupted CPAP for the first hours of life
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Karolinska Institutet
Apnea, Obstructive
Evaluation of the Comfort of a Continuous Positive Airway Pressure Nasal Mask in the Treatment of OSA Syndrome
Continuous positive airway pressure (CPAP) is the first-line treatment for obstructive sleep apnea syndrome (OSA). It consists of a pressure generator connected to a mask applied to the patient's face.
- Trial name
- NINADOM (NCT04925739)
- Testing
- Self-questionnaire on the comfort and general appreciation of a nasal mask, Self-questionnaire on the appearance of CPAP side effects related to the mask, Self-questionnaire on the patient's appreciation of the mask headgear,
- Where
- France
- Volunteers
- 20 people
- Sponsor
- AGIR à Dom
Sleep-Disordered Breathing, Pulmonary Arterial Hypertension
Sleep Disordered Breathing in Precapillary Pulmonary Hypertension: Effect of CPAP Treatment
Evaluation of the effect of CPAP (continuous positive airway pressure ) treatment in PAH (pulmonary arterial hypertension) and CTEPH (chronic thromboembolic pulmonary hypertension) patients suffering from sleep disordered…
- Conditions
- Sleep-Disordered Breathing, Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension
- Trial name
- NCT02583906
- Testing
- CPAP
- Where
- Belgium
- Volunteers
- 8 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Heart Failure, Sleep Apnea Syndromes
Oxygen Versus PAP for Sleep Apnea in Heart Failure
The purpose of this study is to compare three treatment modalities for central, or mixed obstructive and central, sleep apnea in patients with chronic heart failure and reduced ejection fraction.
- Trial name
- OPTIMAL-HF (NCT01807897)
- Testing
- Continuous positive airway pressure, Nocturnal supplemental oxygen, Healthy Lifestyle and Sleep Education
- Where
- 2 sites in United States
- Volunteers
- 74 people
- Sponsor
- VA Office of Research and Development
Respiratory Distress Syndrome, Newborn
Delivery Room Management Trial of Premature Infants at High Risk of Respiratory Distress Syndrome
The best mode of delivery room stabilization for premature infants at high risk for respiratory distress syndrome is unknown. The protocol evaluates the impact of three distinct methods of post-delivery stabilization and…
- Trial name
- NCT00244101
- Testing
- PS Group, NCPAP Group, ISX Group
- Where
- United States
- Volunteers
- 648 people
- Sponsor
- Vermont Oxford Network