Clinical trials: CPAP
Non-Alcoholic Fatty Liver Disease, Obstructive Sleep Apnea
Fatty Liver and Obstructive Sleep Apnea
Non-alcoholic fatty liver disease is associated with obstructive sleep apnea. Abnormalities in liver enzymes can improve following continuous positive airway pressure in patients with obstructive sleep apnea.
- Trial name
- NCT00730873
- Testing
- Continuous positive airway pressure
- Where
- Israel
- Sponsor
- Assaf-Harofeh Medical Center
Obstructive Sleep Apnea
Home Diagnosis and Treatment of Obstructive Sleep Apnea
Obstructive Sleep Apnea (OSA) is a common and underrecognised condition. The diagnosis of OSA is typically made after an in-lab polysomnography (PSG) which requires an overnight stay in a sleep laboratory.
- Trial name
- NCT00139022
- Testing
- Continuous Positive Airway Pressure
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Saskatchewan
Respiratory Distress, Newborn
Effectiveness of HVNI in Preterm Infants With Moderate Respiratory Distress
Neonatal respiratory distress is a common problem in preterm infants. The application of CPAP is widely used in neonatal units as a primary mode of respiratory support for respiratory distress.
- Trial name
- NCT06436222
- Testing
- HVNI
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Respiratory Distress Syndrome
Comparison Between Infant Flow SiPAP and Noninvasive NAVA in the Neonatal Intensive Care Unit
When babies are born premature, they often need help with their breathing. The equipment used to help them breathe is not very comfortable and they sometimes need to be put on a specialized breathing machine with a tube into…
- Trial name
- NCT01588080
- Testing
- Neurally Adjusted Ventilatory Assist (NAVA)
- Where
- 2 sites in Canada
- Volunteers
- 21 people
- Sponsor
- Fraser Health
Obstructive Apnea
Comparison of a Demand Oxygen Delivery
Conducting a randomized control trial of oxygen in children with Down syndrome to treat moderate to severe obstructive sleep apnea.
- Trial name
- DOSA (NCT06609694)
- Testing
- Portable oxygen concentrator Inogen G5 model
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Postoperative Pulmonary Atelectasis, Surgery
Prophylactic nCPAP Following Bowel Surgery (Bio-REB File 11-27)
The purpose of this study is to determine whether prophylactic nasal continuous positive airway pressure (nCPAP) in the post-anaesthesia care unit (PACU) improves post-operative pulmonary function following elective bowel…
- Trial name
- NCT01316575
- Testing
- nCPAP, Low Flow Oxygen
- Volunteers
- 40 people
- Sponsor
- University of Saskatchewan
Preterm, Ventilator Lung; Newborn
Evaluation of Nasal Non Invasive Ventilation in Management of Neonates With Respiratory Distress Using Lung Ultrasound
This study aims to evaluate the effect of non-invasive ventilation (nIPPV) , (nCPAP), and nasal high flow cannula (NHFC) as a primary mode of ventilation in preterm neonates <37 gestational week with moderate to severe RD using…
- Trial name
- NCT06550219
- Testing
- Nasal humidified heated high flow cannula (NHHHC), Nasal intermittent positive pressure ventilation (NIPPV), Nasal continuous positive airway pressure NCPAP
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Obstructive Sleep Apnea, Insomnia
Evaluation of APAP With SensAwake in OSA and Insomnia Patients
The hypothesis is that APAP with SensAwake improves wake-after sleep onset compared to APAP without SensAwake in a patient population with Obstructive Sleep Apnea Syndrome (OSAS) and Insomnia.
- Trial name
- NCT02721329
- Testing
- APAP, APAP with SensAwake
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnea, Hypertension
Assessment of Heart Rate Variability for Predicting Obstructive Sleep Apnea in Patients With Hypertension
This study aims to investigate the relationship between hypertension and obstructive sleep apnea (OSA) using heart rate variability (HRV) as a non-invasive biomarker of autonomic nervous system function.
- Trial name
- HRV-OSA-HTN (NCT07603583)
- Testing
- Polysomnography
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Kaohsiung Armed Forces General Hospital
Respiratory Distress Syndrome, Bronchopulmonary Dysplasia
Comparison of INRECSURE and LISA in Preterm Neonates With RDS
The primary hypothesis of this study is that surfactant administration by INtubate-RECruit-SURfactant-Extubate (IN-REC-SUR-E), via a high frequency oscillatory ventilation recruitment maneuver increases survival without BPD at 36…
- Trial name
- INRECLISA (NCT05711966)
- Testing
- Ventilator for High-frequency Oscillatory Ventilation (HFOV), Less invasive surfactant administration (LISA)
- Where
- Italy
- Volunteers
- 381 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Sleep Apnea Syndromes
Detection of Airway Obstruction by Manometry in Different Sleep Stages and Comparing it to DISE
Patients with OSA receive manometry measurements with Apneagraph (AG) during one night of sleep. All patients are simultaneously evaluated with polysomnography.
- Trial name
- NCT02969551
- Testing
- Manometry and possibly DISE
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Technical University of Munich
Infant, Premature, Diseases, Continuous Positive Airway Pressure
Routine Or Selective Application of a Face Mask for Preterm Infants at Birth: the ROSA Trial
International guidelines recommend giving positive pressure ventilation (PPV) by face mask to newborns who do not breathe or have a slow heart rate at birth.
- Conditions
- Infant, Premature, Diseases, Continuous Positive Airway Pressure, Positive-Pressure Respiration, Resuscitation
- Trial name
- ROSA (NCT04500353)
- Testing
- Face mask application for CPAP and/or PPV delivery
- Where
- Ireland
- Volunteers
- 201 people
- Sponsor
- University College Dublin
Obstructive Sleep Apnea
Head to Head Comparison of Upper Airway Stimulation and Continuous Positive Airway Pressure; a Pilot Study.
To date, there has been no head to head comparison of Upper Airway Stimulation (UAS) and Continuous Positive Airway Pressure (CPAP) utilizing a full night polysomnographic evaluation.
- Trial name
- NCT04191512
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Thomas Jefferson University
Bronchiolitis
HFNC Versus NCPAP/ NPPV in Infants With Severe Bronchiolitis
The purpose of the study was to test the null hypothesis that there is no difference between nasal continuous positive airway pressure / nasal positive pressure ventilation (NCPAP/NPPV) and high flow nasal cannula (HFNC) devices…
- Trial name
- NCT04650230
- Testing
- nasal continuous positive airway pressure / nasal positive pressure ventilation (NCPAP/NPPV) and high flow nasal cannula (HFNC) devices
- Volunteers
- 268 people
- Sponsor
- Children's Hospital of Tunis
Acute Respiratory Failure
Single Breath Counting Test for Acute Respiratory Failure in Emergency Department
The purpose of the study is to determine whether SBCT is a useful tool for diagnosing the main form of failure respiratory acute and to define the SBCT limit associated with insufficiency respiratory in this population, the…
- Trial name
- STARED (NCT06257784)
- Testing
- Oxygen Therapy, Non-Invasive Ventilation (NIV), Invasive Ventilation
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Obstructive Sleep Apnea
Education Programme on Continuous Positive Airway Pressure Treatment
The purpose of this study is to examine whether an education programme would enhance continuous positive airway pressure (CPAP) adherence.
- Trial name
- NCT01173406
- Testing
- CPAP education
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
Knee Replacement Surgery
The Effect of Nasal Continuous Positive Airway Pressure (N-CPAP) on Arterial pCO2 During Spinal Anesthesia
The proposed study intends to investigate several aspects of the respiratory effects of intravenous sedation of patients undergoing spinal anesthesia for knee replacement surgery.
- Trial name
- NCT01622647
- Testing
- Nasal Continuous Positive Airway Pressure (NCPAP)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Pediatrix
Hematologic Disease
Early Application of CPAP in Hematologic
The purpose of this study is to evaluate the use of CPAP in the prevention of acute respiratory failure in neutropenic ( or hematologic malignancy ) patients .CPAP applied preventively in hematological patients with high risk of…
- Trial name
- HEMOCPAP (NCT00507533)
- Testing
- Continuous positive airway pressure
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Turin, Italy
Obstructive Sleep Apnea, Insulin Resistance
Endothelial Damage and Atherosclerosis in Obstructive Sleep Apnea
The investigators hypothesize that obstructive sleep apnea (OSA) may lead to increased formation/accumulation of advanced glycation ends (AGEs), and that the increase in AGEs is contributed in part by increased insulin…
- Conditions
- Obstructive Sleep Apnea, Insulin Resistance, Endothelial Function, Oxidative Stress
- Trial name
- NCT00942643
- Testing
- CPAP machine
- Where
- Hong Kong
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Obstructive Sleep Apnea
Study to Predict the Benefits of First-line Humidification Use and Comparison of the Effect of ThermoSmart™ and no Humidification on Adherence
This study aims to investigate the benefits of using first line heated humidification. The primary objective of this research is to determine the effect of high levels of humidification delivered by ThermoSmart™ on CPAP…
- Trial name
- NCT01742949
- Testing
- Heated humidification (ThermoSmart), No Humidification
- Where
- 4 sites in France
- Volunteers
- 40 people
- Sponsor
- Fisher and Paykel Healthcare
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