Clinical trials: CPAP
Morbid Obesity
Oxygenation and Pulmonary Function in Morbidly Obese Patients Undergoing Bariatric Surgery
This is a randomized controlled study in which morbidly obese patients undergoing bariatric surgery will be recruited in the preoperative clinic.
- Trial name
- NCT01002599
- Testing
- Boussignac TM CPAP, Venturi Face Mask
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- University Health Network, Toronto
Atherothrombosis, Type 2 Diabetes
Aspirin Resistance and Sleep Apnea in Type-2 Diabetic Patients
Type-2 Diabetes and Sleep Apnea Syndrome (SAS) are both related to an increase in platelet activation. Type 2 diabetes is often associated with sleep apnea syndrome with a prevalence up to 60%.
- Conditions
- Atherothrombosis, Type 2 Diabetes, Obstructive Sleep Apnea Syndrome
- Trial name
- AREAS (NCT01788930)
- Testing
- CPAP
- Where
- France
- Volunteers
- 53 people
- Sponsor
- University Hospital, Grenoble
REM Sleep Behavior Disorder, Neurodegenerative Diseases
Striatal Dopamine Transmission in Individuals With Isolated Rapid Eye Movement Sleep With Atonia: a Search for Precursor Biomarker for Neurodegeneration
Background: Previous studies have confirmed that most patients with idiopathic REM sleep behaviour disorder (iRBD) eventually develop neurodegenerative diseases.
- Trial name
- NCT03353207
- Where
- Hong Kong
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Obstructive Sleep Apnea
Oral Appliance Therapy in Obstructive Sleep Apnea
The aim of the study was to compare the effects of a mandibular advancement device (MAD) with those of nasal continuous positive airway pressure(nCPAP) and of an intra-oral placebo device in obstructive sleep apnea (OSA)…
- Trial name
- NCT00950495
- Testing
- Mandibular Advancement Device (MAD), nasal CPAP
- Where
- Netherlands
- Volunteers
- 64 people
- Sponsor
- VU University of Amsterdam
Sleep Apnea, Stroke
Usefulness of Nasal Continuous Positive Airway Pressure (CPAP) Treatment in Patients With a First Ever Stroke and Sleep Apnea Syndrome
MAIN AIMS: to analyze the efficacy of nasal CPAP treatment in patients with ischemic first-ever stroke and Sleep Apnea Syndrome (SAS) in terms of: early neurological outcome, functional recovery, quality of life influence, stroke…
- Conditions
- Sleep Apnea, Stroke, Cardiovascular Disease
- Trial name
- NCT00202501
- Testing
- Nasal CPAP (Continuous Positive Airway Pressure)
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Pulmonary Atelectasis
Ventilation Strategy Reduces Postoperative Atelectasis
Atelectasis is common during and after general anesthesia. The investigators hypothesized that a ventilation strategy with a combination of 1) continuous positive airway pressure (CPAP) or positive end-expiratory pressure (PEEP)…
- Trial name
- NCT01911923
- Testing
- No CPAP/PEEP and 100 % oxygen, CPAP/PEEP and 30 % oxygen
- Where
- Sweden
- Sponsor
- Region Västmanland
Heart Failure, OSA - Obstructive Sleep Apnea
Mandibular Advancement to Reduce Ventricular Load and Improve Quality-of-life in Heart Failure
Heart failure with reduced ejection fraction (HFrEF) is a serious condition that limits daily activities and often leads to hospital stays and early death.
- Trial name
- MARVEL-HF (NCT07460505)
- Testing
- Mandibular advancement device
- Where
- Singapore
- Volunteers
- 328 people
- Sponsor
- National University Hospital, Singapore
Heart Failure
Acute Effect of Continuous Positive Airway Pressure in Heart Failure
Acute effects of CPAP on diastolic function in patients with compensated heart failure (CHF) are unknown. The investigators hypothesized that acutely CPAP improves diastolic function, which is associated with increases exercise…
- Trial name
- NCT01088854
- Testing
- CPAP
- Where
- Brazil
- Volunteers
- 2 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
High-flow Nasal Cannula, Exercise Capacity
Study on Optimal Oxygen Concentration During Pulmonary Rehabilitation
The purpose of this study is to compare the exercise capacity between high SpO2 (Minimum SpO2 94-96%) value during pulmonary rehabilitation and low SpO2 (Minimum SpO2 84-86%) value during pulmonary rehabilitation for the patients…
- Conditions
- High-flow Nasal Cannula, Exercise Capacity, Chronic Respiratory Failure, Optimal SpO2 Value
- Trial name
- NCT04481295
- Testing
- High-flow nasal cannula, Low SpO2
- Where
- Japan
- Volunteers
- 32 people
- Sponsor
- National Hospital Organization Minami Kyoto Hospital
Hypoxemia, COPD
The Effectiveness of Two Distinct Ventilation Strategies Escalating Positive End Expiratory Pressure (PEEP) and Lung Recruitment Maneuvers in Improving Oxygenation
This study evaluates and compares the effectiveness of two distinct ventilation strategies-escalating PEEP and lung recruitment maneuvers-in improving oxygenation (i.e., managing hypoxemia) in COPD patients undergoing VATS.
- Trial name
- NCT06847412
- Testing
- Escalating PEEP, Sustained inflation
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Insomnia
Ramelteon for Complex Insomnia in Veterans With PTSD
Obstructive sleep apnea is commonly reported in Veterans with post-traumatic stress disorder, which can potentiate symptoms of anxiety and depression, daytime symptoms and worsen nightmares.
- Trial name
- DORMI (NCT03265951)
- Testing
- Ramelteon, Usual Care
- Where
- United States
- Sponsor
- State University of New York at Buffalo
Obstructive Sleep Apnea of Adult
Endothelial Function in Obstructive Sleep Apnea
Obstructive sleep apnea (OSA), a condition that affects a quarter of the Western adults, triples the risk for cardiovascular diseases and increases all-cause mortality.
- Trial name
- NCT03122639
- Testing
- Atorvastatin 10mg
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Columbia University
Acute Myocardial Infarction
Noninvasive Ventilation in Acute Myocardial Infarction
Cardiovascular diseases, especially acute myocardial infarction (AMI), represent the major cause of mortality and morbidity in the world.
- Trial name
- NCT01484795
- Testing
- BILEVEL (Respironics), Continuos positive airway pressure (Respironics)
- Volunteers
- 10 people
- Sponsor
- Centro Universitário Augusto Motta
Chronic Obstructive Pulmonary Disease
The Use of High Frequency Oscillations With NIV in Hypercapnic COPD Participants
Chronic Obstructive Pulmonary Disease (COPD) is a major cause of chronic morbidity and mortality throughout the world, being the fourth leading cause of death in the world.
- Trial name
- NCT02680639
- Testing
- BiPAP Synchrony ventilator
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Philips Respironics
Heart Failure, Sleep Apnea Syndromes
Oxygen Versus PAP for Sleep Apnea in Heart Failure
The purpose of this study is to compare three treatment modalities for central, or mixed obstructive and central, sleep apnea in patients with chronic heart failure and reduced ejection fraction.
- Trial name
- OPTIMAL-HF (NCT01807897)
- Testing
- Continuous positive airway pressure, Nocturnal supplemental oxygen, Healthy Lifestyle and Sleep Education
- Where
- 2 sites in United States
- Volunteers
- 74 people
- Sponsor
- VA Office of Research and Development
Obstructive Sleep Apnea, CPAP
The Outcome of CPAP Titration Under Sleep Endoscopy
The outcome of CPAP titration under sleep endoscopy: A randomized controlled crossover trial
- Conditions
- Obstructive Sleep Apnea, CPAP, DISE
- Trial name
- NCT03523013
- Testing
- CPAP
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Chang Gung Memorial Hospital
Obstructive Sleep Apnea Syndrome
Evaluation of a New Medical Device AL539 in Patients With Obstructive Apneas Sleep Syndrome
Continuous Positive Airway Pressure (CPAP) is the standard treatment in patients with Obstructive Sleep Apnea Syndrome (OSAS). The goal of the study is to evaluate CPAP treatment duration recorded by the AL539 during attended…
- Trial name
- AL539 (NCT01441622)
- Testing
- AL539 (SRETT)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Air Liquide Santé International
The Screening and the Treatment of ECG Holter and Sleep Apnea
The Screening and the Treatment of ECG Holter and Sleep Apnea
Sleep quality affect working and learning performance; poor quality of sleep is one of the common problems of modern people. Traditionally, polysomnography is a recognized standard for sleep quality assessment.
- Trial name
- NCT05928923
- Testing
- CPAP
- Where
- Taiwan
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Atelectasis
The Effect of Oscillation and Lung Expansion (OLE) Therapy in Prolonged Mechanical Ventilated Patients With Atelectasis Evaluated in Multiple Methods
High frequency chest wall oscillation (HFCWO) is currently one of the most common and widespread mechanical airway clearance techniques (ACTs) in clinical practice in China.
- Trial name
- NCT07451405
- Testing
- High frequency chest wall oscillation or other airway clearance therapy, Oscillation and lung expansion
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Capital Medical University
Noninvasive Ventilation, COPD
Effect of Web-Based Adaptation and Insomnia Severity in Individuals Using Noninvasive Ventilators at Home
Home use of the NIV device, which is used to manage respiratory failure, one of the most disturbing symptoms due to COPD, will continue to increase.
- Trial name
- NCT06343324
- Testing
- Web-based education
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- KTO Karatay University
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