Clinical trials: CPAP
Mechanical Ventilation
DIAPHRAGM STRENGTH AND LUNG VOLUMES
Diaphragm dysfunction (loss of diaphragm strength) is common in the intensive care unit (ICU) patients using ventilators. The diaphragm is the main muscle of respiration and its dysfunction can prolong mechanical ventilation and…
- Trial name
- DIAVOLA (NCT07206459)
- Testing
- Healthy Patients, Critically Care Patients
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Preterm Infants
NHFOV vs. NCPAP as a Primary Treatment to Neonatal Respiratory Distress Syndrome(NRDS)
The investigators compared advantages and disadvantages of two forms of noninvasive respiratory support -noninvasive high-frequency oscillatory ventilation (nHFOV) or nasal continuous positive airway pressure (nCPAP) -as a…
- Trial name
- NCT03099694
- Testing
- noninvasive high-frequency ventilation (nHFOV), nasal continuous positive airway pressure (nCPAP)
- Where
- China
- Volunteers
- 340 people
- Sponsor
- Xingwang Zhu
Obstructive Sleep Apnea, Sleep Apnea
Do Endotypes Predict Response and Sequelae in OSA Patients
This study will investigate why some people have Obstructive Sleep Apnea (OSA) and how the underlying cause may relate to OSA manifestations (including sleepiness and high blood pressure) and response to different therapeutic…
- Conditions
- Obstructive Sleep Apnea, Sleep Apnea, Sleep Apnea, Obstructive, Sleep
- Trial name
- ExPRESSION (NCT04875364)
- Testing
- Eszopiclone, Supplemental Oxygen, Continuous Positive Airway Pressure (CPAP)
- Where
- United States
- Volunteers
- 233 people
- Sponsor
- University of California, San Diego
Myofascial Pain Syndrome of Neck, Trigger Point Pain, Myofascial
Effects of Pressure Release of Myofascial Trigger Points on Mechanical Neck Pain.
The study aims to compare the effectiveness of myofascial trigger point treatment using pressure release versus a control group in patients with mechanical neck pain, randomly assigned.
- Conditions
- Myofascial Pain Syndrome of Neck, Trigger Point Pain, Myofascial, Myofacial Pain
- Trial name
- NCT06051799
- Testing
- Myofascial trigger points pressure release, Therapeutic exercise and postural hygiene
- Where
- Spain
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Feeding Intolerance, Abdominal Distension
Abdominal Binders to Minimize Enteral Nutrition Disruptions for Preterm Infants On Non-Invasive Respiratory Support
The goal of this study is to learn if a foam belly strap, called "NeoBellyBand," can help with belly bloating, pauses in feedings, feeding success, and earlier discharge home for preterm infants who are requiring pressurized…
- Trial name
- ABMENDPIONIR (NCT07219784)
- Testing
- An abdominal binder
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Albany Medical College
Obstructive Sleep Apnea
TPAP for Comfort in OSA
TheraPAP is a prototype device (with full documented electrical and isolation safety) being developed by SleepRes for the treatment of obstructive sleep apnea (OSA) that can deliver either standard CPAP at a set pressure or what…
- Trial name
- NCT06264128
- Testing
- TPAP, CPAP
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- SleepRes Inc.
Heart Failure
Ventilatory Support Associated With Exercise in Heart Failure
Due to the symptoms of heart failure (HF), as dyspnea and fatigue, patients have a reduced functional capacity, evidenced during usual daily activities and exercises.
- Trial name
- SVNI (NCT02384798)
- Testing
- noninvasive ventilatory support, interval training
- Volunteers
- 60 people
- Sponsor
- Federal University of Bahia
Obstructive Sleep Apnea (OSA)
Metabolic Study of Sleep Apnea in Men and Women
The purpose of this study is to look at the metabolic (use of energy) and hormonal features of sleep problems in men and women.
- Trial name
- NCT00706511
- Testing
- CPAP
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Chicago
Afib, Sleep Apnea Syndrome, Obstructive
Sleep Apnea Triggers of Atrial Fibrillation: N-of-1 Randomized Control Trial (SPARTA):
A pilot N-of-1 randomized controlled trial evaluating the effectiveness of a personalized CPAP intervention in reducing atrial fibrillation (AF) burden and improving AF-related quality of life in patients with moderate to severe…
- Conditions
- Afib, Sleep Apnea Syndrome, Obstructive, CPAP
- Trial name
- SPARTA (NCT07087587)
- Testing
- CPAP
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- The Cleveland Clinic
Sleep Apnea, Obstructive
Compliance With Continuous Positive Airway Pressure Therapy in Patients With Obstructive Sleep Apnea Syndrome
The aim of the study is to know the adherence to treatment and compliance of patients diagnosed with SAHS and with indication of CPAP from the sleep unit of the Hospital de Sabadell.
- Trial name
- CPAPSH (NCT03776084)
- Testing
- Continuous Positive Airway Pressure
- Where
- Spain
- Volunteers
- 405 people
- Sponsor
- Corporacion Parc Tauli
Parainfluenza
An Open Label Study to Examine the Effects of DAS181 Administered by Dry Powder Inhaler (DPI) or Nebulized Formulation in Immunocompromised Subjects With Parainfluenza (PIV) Infection
This protocol will seek to enroll up to 60 immunocompromised subjects diagnosed with parainfluenza infection. All subjects will have additional PK and Immunogenicity blood samples collected.
- Trial name
- PIV (NCT01924793)
- Testing
- DAS181-F02 Dry Powder in Bulk, DAS181-F02 Nebulized Formulation Inhaled Dose
- Where
- 23 sites in United States
- Volunteers
- 23 people
- Sponsor
- Ansun Biopharma, Inc.
OSA, Adherence, Patient
Adherence to CPAP in Patients With OSA. Ten Year Follow up
The management of OSA is aimed to improve symptoms and mitigate reduce other health consequences. Continuous Positive Airway Pressure (CPAP) is the recognized treatment for OSA, able to reverse the pathophysiology of OSA and…
- Conditions
- OSA, Adherence, Patient, CPAP
- Trial name
- NCT03644121
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- Maugeri Foundation
One-Lung Ventilation, Thoracic Surgery, Video-Assisted
Comparison Between CPAP and HFJV During One-lung Ventilation in VATS
This study compares two ventilatory techniques (continuous positive airway pressure vs high frequency jet ventilation) during one-lung ventilation (OLV) in video-assisted thoracic surgery (VATS).
- Trial name
- NCT03296449
- Testing
- CPAP, HFJV
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital General Universitario de Alicante
Intensive Care, Neonatal, Neonatal Respiratory Distress Syndrome
Breastfeeding Infants Receiving Respiratory Support Trial
The purpose of this study is to assess whether two methods of breathing support in babies called 'Humidified High-Flow Nasal Cannula' oxygen (HHFNC) and 'nasal Continuous Positive Airways Pressure' (nCPAP) are compatible with…
- Conditions
- Intensive Care, Neonatal, Neonatal Respiratory Distress Syndrome, Continuous Positive Airway Pressure, Breast Feeding
- Trial name
- BIRRST (NCT02999165)
- Testing
- Breast feeding, Nasogastric feeding
- Where
- United Kingdom
- Volunteers
- 1 people
- Sponsor
- Imperial College Healthcare NHS Trust
Neonatal Respiratory Distress Related Conditions
Oscillatory Versus Non-oscillatory Nasal Continuous Airway Pressure Neonatal Respiratory Support
Controlled randomized trial looking at Standard nasal continuous airway pressure (CPAP) respiratory support versus High Frequency CPAP in neonates who require respiratory support or who are being extubated and require support…
- Trial name
- NCT03711565
- Testing
- Regular Nasal CPAP using a conventional ventilator, High Frequency Nasal CPAP
- Where
- United States
- Sponsor
- University of California, Davis
OSA, Left Ventricular Dysfunction
Evaluation of Left Ventricular Function and Therapeutic Effect of CPAP in Patients With OSAS by 3D STE
The changes of left ventricular function in patients with sleep apnea were studied by three-dimensional speckle-tracking echocardiography to evaluate the changes of left ventricular function after CPAP treatment
- Trial name
- NCT04957004
- Testing
- CPAP
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Sleep Apnea, Pregnancy
Pregnancy, Sleep Disordered Breathing and Peripartum Complications
Sleep disordered breathing (SDB) during pregnancy is a modifiable risk factor for poor maternal and fetal outcomes. The investigators propose a prospective observational study to assess the utility of continuous positive airway…
- Trial name
- NCT02651649
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Postural Tachycardia Syndrome (POTS)
Splanchnic Venous Capacitance in Postural Tachycardia Syndrome
Postural tachycardia syndrome (POTS) affects ≈3 million young people, characterized by chronic presyncopal symptoms characterized by dizziness, lightheadedness, and orthostatic tachycardia that occur while standing.
- Trial name
- NCT05375968
- Testing
- Measurement of Splanchnic venous capacitance(SVC)done at Baseline and after 90 min of 75 g glucose in Healthy Controls POTS patients, Measurement of Splanchnic venous capacitance(SVC)done at Baseline and after 90 min of 75 g glucose in Healthy Controls, Compare change is SVC and SMA flow due to GIP antagonist GIP(3-30)NH2
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Sleep Apnea Syndromes
Effect of Self-Management on Improving Sleep Apnea Outcomes
Obstructive sleep apnea syndrome (OSA) is a common sleep disorder that is associated with serious medical and psychological complications.
- Trial name
- NCT00310310
- Testing
- Sleep Apnea Self-Management Program, Usual care
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- VA Office of Research and Development
Asthma (Diagnosis), OSA - Obstructive Sleep Apnea
Obstructive Sleep Apnoea and Difficult Asthma (OSADA)
The OSADA (Obstructive Sleep Apnoea in Difficult Asthma) trial is an open-label, randomized control trial investigating the impact of diagnosing and treating obstructive sleep apnoea (OSA) on a asthma control in patients with…
- Conditions
- Asthma (Diagnosis), OSA - Obstructive Sleep Apnea, CPAP Treatment
- Trial name
- OSADA (NCT07160868)
- Testing
- Continuous positive airway pressure (CPAP)
- Where
- Ireland
- Volunteers
- 80 people
- Sponsor
- St. James's Hospital, Ireland
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.