Clinical trials: CPAP, completed
Respiratory Distress Syndrome
Evaluation of the Diagnostic Performance of Electrical Impedance Tomography to Detect Situations at Risk of Lesions Induced by Conventional Mechanical Ventilation in ARDS
Acute respiratory distress syndrome remains a serious condition, with a mortality rate of between 30 and 50%. The use of mechanical ventilation with small tidal volumes, and by limiting the plateau pressure in the respiratory…
- Trial name
- NCT02896673
- Testing
- ventilatory conditions and measures with scanner and EIT
- Where
- France
- Volunteers
- 3 people
- Sponsor
- Hospices Civils de Lyon
Respiratory Distress Syndrome, Newborn
High Flow Nasal Cannula Versus Nasal Continuous Positive Airway Pressure for Respiratory Support of Preterm Neonates
This work is designed to: 1. Evaluate the efficacy of HHHFNC in comparison with nCPAP in preterm neonates. 2. Investigate hemodynamic changes associated with HHHFNC in comparison to nCPAP in preterm neonates during periods of…
- Trial name
- NCT04238273
- Testing
- Functional Echocardiography
- Where
- Egypt
- Volunteers
- 123 people
- Sponsor
- Ain Shams University
Obstructive Sleep Apnea of Adult
Endothelial Function in Obstructive Sleep Apnea
Obstructive sleep apnea (OSA), a condition that affects a quarter of the Western adults, triples the risk for cardiovascular diseases and increases all-cause mortality.
- Trial name
- NCT03122639
- Testing
- Atorvastatin 10mg
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Columbia University
OSA
OSA Recurrence in CPAP Withdrawal
Continuous positive airway pressure (CPAP) therapy is the most effective Treatment for obstructive sleep apnoea (OSA ). However, adherence to CPAP is often limited.
- Trial name
- NCT03472612
- Testing
- CPAP withdrawal
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Stroke, Sleep Apnea, Obstructive
Stroke and CPAP Outcome Study: A Sham-controlled Trial of CPAP Among Stroke Rehabilitation Patients
The purpose of this study is to assess the effect of continuous positive airway pressure (CPAP) on functional outcome in patients with acute stroke, the investigators conducted a sham-controlled, double-blind pilot trial during…
- Trial name
- SCOUTS (NCT02551757)
- Testing
- Auto-titrating CPAP
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Washington
Ventilation
Haemodynamic Changes With Different Noninvasive Respiratory Modes for Primary Respiratory Support in Preterm Neonates
to evaluate the efficacy of Nasal high frequency oscillatory ventilation (NHFOV) and Vapotherm in comparison to nasal Continuous positive airway pressure (CPAP) as a primary noninvasive respiratory support in preterm neonates
- Trial name
- RDS (NCT06737003)
- Testing
- Nasal high frequency oscillatory ventilation, Vapotherm Group, Nasal CPAP Group
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Respiratory Insufficiency
High Flow Nasal Cannula Versus Nasal Continuous Positive Airway Pressure
The purpose of this study is to compare two common methods of providing respiratory support: nasal continuous airway pressure and high flow nasal cannula to see what effect it has on babies breathing.
- Trial name
- NCT01531465
- Testing
- Pulmonary Function Testing & esophageal pressure monitoring, Pulmonary function testing and esophageal pressure
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Morbid Obesity
Effect of Boussignac CPAP Ventilation on PaO2 and PaO2/FiO2 Ratio in Morbidly Obese Patients Undergoing Bariatric Surgery
The purpose of this study is to determine if the application of Boussignac continuous positive airway pressure (CPAP) immediately after extubation improves PaO2 and PaO2/FiO2 ratio in morbidly obese patients undergoing gastric…
- Trial name
- NCT02297828
- Testing
- Boussignac CPAP, Venturi face mask
- Where
- Portugal
- Volunteers
- 24 people
- Sponsor
- Centro Hospitalar do Porto
Obstructive Sleep Apnea
Revised Algorithm for Next Generation DeVilbiss Healthcare AutoAdjust Continuous Positive Airway Pressure (CPAP)
The purpose of this protocol is to improve the current FDA-approved continuous positive pressure auto-titration algorithm, including treatment precision, residual disease detection characteristics and phenotyping with the…
- Trial name
- NCT01797705
- Testing
- DeVilbiss AutoAdjust CPAP with revised algorithm
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- DeVilbiss Healthcare LLC
Gestational Diabetes, Sleep Apnea
Sleep Apnea and Gestational Diabetes
The investigators hypothesize that pregnant women with gestational diabetes will have a high incidence of sleep apnea, and that the treatment of sleep apnea will lead to improved glucose control in these women.
- Trial name
- NCT02108197
- Testing
- Continuous positive airway pressure (S9, ResMed)
- Where
- Thailand
- Volunteers
- 82 people
- Sponsor
- Ramathibodi Hospital
Heart Failure, Sleep Apnea Syndromes
Oxygen Versus PAP for Sleep Apnea in Heart Failure
The purpose of this study is to compare three treatment modalities for central, or mixed obstructive and central, sleep apnea in patients with chronic heart failure and reduced ejection fraction.
- Trial name
- OPTIMAL-HF (NCT01807897)
- Testing
- Continuous positive airway pressure, Nocturnal supplemental oxygen, Healthy Lifestyle and Sleep Education
- Where
- 2 sites in United States
- Volunteers
- 74 people
- Sponsor
- VA Office of Research and Development
Obstructive Sleep Apnea, Spinal Cord Injuries
Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea
Mild intermittent hypoxia (IH) initiates sustained increases in chest wall and upper airway muscle activity in humans. This sustained increase is a form of respiratory plasticity known as long-term facilitation (LTF).
- Trial name
- NCT03736382
- Testing
- Mild intermittent hypoxia, Continuous positive airway pressure (CPAP)
- Where
- 2 sites in United States
- Volunteers
- 47 people
- Sponsor
- Wayne State University
Obstructive Sleep Apnoea (OSA)
Breath Analysis in Obstructive Sleep Apnoea
Clinical trial in patients with obstructive sleep apnoea that are randomised to either continue or withdraw continuous positive airway pressure therapy to identify a disease-specific exhaled breath pattern by mass spectrometry.
- Trial name
- NCT02050425
- Testing
- CPAP
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University of Zurich
Sleep Apnea, Obstructive, Patient Compliance
Tailored Intervention to Promote Positive Airway Pressure Adherence
The purpose of this study is to examine the feasibility of a tailored (i.e., individualized) intervention to promote adherence to continuous positive airway pressure therapy (CPAP) in adults with newly-diagnosed, CPAP treated…
- Trial name
- SCIP-PA (NCT01454830)
- Testing
- Tailored, Usual care
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Milton S. Hershey Medical Center
Asthma, Obstructive Sleep Apnea
Asthma and Obstructive Sleep Apnea (OSA)
Obstructive sleep apnea (OSA) is a common but under-diagnosed form of sleep disordered breathing (SDB). Asthma is a common disease with rising prevalence, which continues to pose significant morbidity and costs.
- Trial name
- NCT01026298
- Testing
- FDA-Approved Treatment
- Where
- United States
- Volunteers
- 744 people
- Sponsor
- University of Wisconsin, Madison
Heart Defects, Congenital, Surgery
Feasibility Study Over the NAVA Mode in Noninvasive Ventilation After Cardiac Surgery in Infants.
Neonates who underwent cardiac surgery with cardiopulmonary bypass almost always require non-invasive respiratory support (NIV) in relay to conventional ventilation.
- Trial name
- NIVNAVA (NCT01570933)
- Testing
- NivNava, Cpap
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Respiratory Distress Syndrome in Premature Infant
Physiological Changes With High-Flow Nasal Cannula
To measure changes in physiologic parameters in extremely low birthweight (ELBW) infants on high-flow nasal cannula compared to nasal continuous positive airway pressure (nCPAP).
- Trial name
- NCT03700606
- Testing
- High flow nasal cannula, Nasal CPAP
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Sharp HealthCare
Acute Hypoxemic Respiratory Failure
Tidal Volume in Patients With "de Novo" Acute Hypoxemic Respiratory Failure
Protective ventilation can be difficult to achieve during noninvasive ventilation for "de novo"acute hypoxemic respiratory failure (i.e., not due to exacerbation of chronic lung disease or cardiac failure).Recent data suggest…
- Trial name
- DENOVT (NCT04741659)
- Testing
- Ventimask, High Flow Nasal cannula (HFNC), Helmet CPAP
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
COVID, Pneumonia, Viral
Lung Damage Caused by SARS-CoV-2 Pneumonia (COVID-19)
Pneumonia is a recurrent element of COVID-19 infection, it is often associated with development of respiratory failure and patients frequently need various degrees of oxygen therapy up to non invasive ventilation (NIV-CPAP) and…
- Conditions
- COVID, Pneumonia, Viral, Barotrauma, Interstitial Lung Disease
- Trial name
- SequelaeCov (NCT04435327)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Milano Bicocca
Obstructive Sleep Apnea
Automated Graduated CPAP (AGPAP) for Improved Adherence in Newly Diagnosed Obstructive Sleep Apnea (OSA) Patients
Although positive airway pressure (PAP) is a highly effective treatment for sleep apnea, adherence to therapy remains an obstacle.
- Trial name
- NCT01450540
- Testing
- REMstar Auto A-Flex, modified REMstar Auto A-Flex with AGPAP
- Where
- 5 sites in United States
- Volunteers
- 241 people
- Sponsor
- Philips Respironics