Clinical trials: CPAP
Obstructive Sleep Apnea, Vasovagal Syncope
Clinical Association Between Obstructive Sleep Apnea, Facial Pigmentation, and Vasovagal Symptoms.
The goal of this prospective cohort study is to study patients referred for sleep study by in-lab polysomnography in the Jordan University Hospital and the Jordan Hospital or with an at-home sleep study kit.
- Conditions
- Obstructive Sleep Apnea, Vasovagal Syncope, Smoking, Acanthosis Nigricans
- Trial name
- VasOSA (NCT06331819)
- Testing
- In-lab polysomnography, Continuous positive airway pressure, Home sleep study device
- Where
- Jordan
- Volunteers
- 200 people
- Sponsor
- Jordan Collaborating Cardiology Group
Obstructive Sleep Apnea, Hypercapnia
Home-Based Diagnosis and Management of Sleep-Related Breathing Disorders in Spinal Cord Injury
Patients with spinal cord injury (SCI) usually breathe without any mechanical assistance, but significant breathing problems occur often during sleep, either because the upper airway closes (obstructive sleep apnea; OSA), or…
- Conditions
- Obstructive Sleep Apnea, Hypercapnia, Spinal Cord Injury
- Trial name
- NCT01882257
- Testing
- BiPAP, BiPAP/AVAPS (Phillips Respironics)
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- University of Michigan
Obstructive Sleep Apnea, IgA Nephropathy
The Effect of OSA on Severity and Prognosis of Patients With IgAN
This study aims to investigate the influence of obstructive sleep apnea hypopnea syndrome (OSA) on the severity and prognosis of patients with IgA nephropathy (IgAN), and to evaluate the therapeutic effect of continuous positive…
- Trial name
- NCT06393036
- Testing
- Continuous Positive Airway Pressure
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
Obesity, Anaesthesia
CPAP/PSV Preoxygenation in Obese Patients
The purpose of this study is to determine whether continuouse positive airway pressure (CPAP), during induction of anaesthesia in morbidly obese patients, result in higher levels of oxygen in the blood.
- Trial name
- NCT01780571
- Testing
- CPAP 5 cm H2O + PSV 5 cm H2O
- Where
- Sweden
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Chronic Obstructive Pulmonary Disease Exacerbation
Evaluation of Oxygen Delivery Methods in Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)
To examine the effects of oxygen therapy methods applied as indicated in COPD acute exacerbations on blood gas results and spirometric measurements.
- Trial name
- NCT06561464
- Testing
- EzPAP®, Non-invasive mechanical ventilation (NIMV)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Obstructive Sleep Apnea-hypopnea Syndrome
Sleep Apnea Syndrome and Vitamin D
Obstructive sleep apnea/hypopnea syndrome (OSAHS) is a highly prevalent disorder with multiple comorbidities. OSAHS is characterized by repetitive episodes of airflow reduction (hypopnoea) or cessation (apnoea) due to upper…
- Trial name
- NCT01323218
- Testing
- 25 OH vitamin D
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Neoplasms
Chest Imaging of Lung Nodule(s) Under High-frequency Non-invasive Ventilation (HF-NIV)
Imaging of chest disorders is mainly achieved by using computed tomography. This is especially the case for detection, morphologic assessment and followup of pulmonary nodules.
- Trial name
- NCT03553368
- Testing
- HF-NIV-MR, HF-NIV-PET, MR
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Obstructive Sleep Apnea, Obesity
Consequences of Obstructive Sleep Apnea on Respiratory Function Following Weight-loss Surgery
The investigators propose to compare two different treatments, continuous positive airway pressure (CPAP) versus breathing of atmospheric pressure, in subjects with obstructive sleep apnea (OSA)recovering from weight loss surgery…
- Trial name
- NCT01697878
- Testing
- CPAP followed by atmospheric pressure, Atmospheric pressure followed by CPAP
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Massachusetts General Hospital
Sleep Apnea, Sleep Disordered Breathing
Sleepiness and the Effects of CPAP on Salivary Cortisol and Alpha-Amylase Levels in Patients With Sleep Apnea
Patients with Obstructive Sleep Apnea Syndrome (OSAS) will evidence higher levels of salivary cortisol and alpha-amylase levels prior to use of placebo and continuous positive airway pressure (CPAP) and will evidence a decrease…
- Trial name
- NCT01196117
- Testing
- 14 days of CPAP therapy
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Medical College of Wisconsin
Transient Tachypnea of Newborn
Comparison of Nasal CPAP and Nasal SIMV in Transient Tachypnea of Newborn
The investigators aimed to compare the efficacy of nasal SIMV and nasal CPAP in patients with wet lung.
- Trial name
- NCT01499238
- Testing
- Nasal SIMV, nasal CPAP
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Pulmonary Complications
Comparison of BiPAP and ٰIS in Reducing Post CABG Pulmonary Complications
To evaluate the effect of Bi-level Positive Airway Pressure (BiPAP) and Incentive Spirometry (IS) in post CABG patients.
- Trial name
- NCT04700215
- Testing
- BiPAP, Incentive spirometry
- Where
- Pakistan
- Volunteers
- 350 people
- Sponsor
- Chaudhry Pervaiz Elahi Institute of Cardiology
Parkinson's Disease, Sleep Disordered Breathing
Cognitive Benefits of Treating Sleep Apnea in Parkinson's Disease
Patients with sleep disordered breathing (SDB), also called sleep apnea, experience nighttime disrupted sleep and, because they stop breathing for short periods during the night, do not get sufficient oxygen to their brains.
- Trial name
- TAP (NCT00492115)
- Testing
- Continuous positive airway pressure (CPAP)
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- University of California, San Diego
Covid-19
Non-invasive Ventilatory Support of Patients Affected by COVID-19
Prospective, observational, multicenter study aiming to evaluate the number of COVID-19 pneumonia related patients treated with non-invasive ventilatory support outside the intensive care unit.
- Trial name
- WARd-COVID (NCT04382235)
- Testing
- Non-invasive ventilatory support
- Where
- 34 sites in Italy
- Volunteers
- 909 people
- Sponsor
- University of Milano Bicocca
Obstructive Sleep Apnoea, Obesity
Peripheral Vascular Function in Obstructive Sleep Apnoea
Peripheral vascular function is impaired in people with obstructive sleep apnoea who are untreated compared with age-, weight- and sex-matched healthy controls.
- Trial name
- NCT01619748
- Where
- 2 sites in United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Pediatric Obstructive Sleep Apnea, Pediatric Obesity
Treating Children With Obstructive Sleep Apnea After Surgery Failure
The aim of this study is to evaluate the potential improvement of sleep quality in children who have residual obstructive sleep apnea, using either an orthodontic intervention or continuous positive airway pressure (CPAP), versus…
- Trial name
- NCT03821831
- Testing
- Continuous Positive Airway Pressure, Orthodontic intervention
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- University of Alberta
Polycystic Ovary Syndrome, Obstructive Sleep Apnea
Restoring Metabolic and Reproductive Health With Sleep in PCOS Study, CPAP Trial
In this study, the researchers are trying to learn more about the relationship between Polycystic Ovary Syndrome and Obstructive Sleep Apnea (OSA).
- Trial name
- NCT05920694
- Testing
- Continuous Positive Airway Pressure Device (CPAP), Delayed Continuous Positive Airway Pressure Device (CPAP)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Oropharyngeal Dysphagia, Laryngectomy; Status
CPAP to Improve Swallow Function Post Total Laryngectomy
Investigator initiated prospective study to determine whether use of Continuous Positive Airway Pressure (CPAP) can improve the swallow function in patients who underwent total laryngectomy and are experiencing difficulty…
- Trial name
- NCT03328702
- Testing
- Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, Davis
Oxidative Stress in Neonates, Near Infrared Spectroscopy
Transfusion-Related Changes in Oxidative Stress Biomarkers in Neonates
Reactive oxygen species (ROS), which include peroxides, are generated in the human body as by-products of cellular metabolism. In small amounts, they fulfill important physiological functions.
- Conditions
- Oxidative Stress in Neonates, Near Infrared Spectroscopy, Fetal Hemoglobin, Erythrocyte Transfusion
- Trial name
- NEO-REDOX (NCT07672275)
- Testing
- Peroxide analysis-TOC Omnignostica Forschungs GmbH, Near Infrared Imaging
- Where
- Austria
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Sleep Apnea, Obstructive
The Phenotyping and Genotyping of Taiwanese Patients With Obstructive Sleep Apnea
The growing evidence showed that the OSA is a heritable complex genetic disease where the genetic basis contributed the development of OSA and its sequel. The phenotyping of OSA include high level and intermediate level.
- Trial name
- NCT02038751
- Where
- Taiwan
- Volunteers
- 360 people
- Sponsor
- National Taiwan University Hospital
Severe High Altitude Pulmonary Edema, Severe High Altitude Cerebral Edema
Key Diagnostic & Therapeutic Technologies for Severe Acute High Altitude Disease (SAHAD): Integration and Application
This study aims to establish a key technical system for the diagnosis and treatment of severe acute mountain sickness based on real-world clinical data in Xizang, develop standardized diagnosis and treatment protocols and an…
- Trial name
- SAHAD (NCT07639931)
- Testing
- Multicenter study of HAPE：CPAP or BiPAP Group, Multicenter study of HAPE group：NO Group, Protocol for Proteomics and Peptidomics Study of HAPE：Case Group
- Where
- China
- Volunteers
- 3,035 people, healthy volunteers welcome
- Sponsor
- Tibet Autonomous Region People's Hospital
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