Clinical trials: CPAP
OSA, Rocuronium
Effect of Rocuronium on the Acute Hypoxic Ventilatory Response in Patients With Obstructive Sleep Apnea
This study describe the effect of partial neuromuscular blockade of rocuronium on the acute hypoxic ventilatory response in patients with OSA before and after 3 month of CPAP treatment.
- Conditions
- OSA, Rocuronium, Neuromuscular Blockade, Hypoxic Ventilatory Response
- Trial name
- NCT01672606
- Testing
- Rocuronium
- Where
- Sweden
- Volunteers
- 11 people
- Sponsor
- Malin Jonsson Fagerlund
Nasal Obstruction, Apnea, Obstructive Sleep
The Role of the Nose in Snoring and Sleep Apnea
We intend to study, in depth, the quantitative and qualitative properties of nasal respiration in sleep-disordered breathing and sleep apnea and its relation to (CPAP) treatment with the final goal of improving patient outcome.
- Trial name
- NCT03072173
- Testing
- Xylometazoline
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- Lovisenberg Diakonale Hospital
Respiratory Insufficiency in Children, Noninvasive Ventilation
Validation of Indirect Calorimetry in Children Undergoing Non-invasive Ventilation
Nutritional status in critically ill pediatric patients is considered a fundamental prognostic factor in terms of mortality, morbidity, complications and outcome.
- Conditions
- Respiratory Insufficiency in Children, Noninvasive Ventilation, Nutrition Assessment
- Trial name
- CALO-NIV (NCT03824249)
- Testing
- Indirect Calorimetry
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Coronary Artery Disease, Obstructive Sleep Apnea
Continuous Positive Airway Pressure (CPAP) Treatment in Coronary Artery Disease and Sleep Apnea
Obstructive sleep apnea (OSA) worsens the prognosis in patients with coronary artery disease (CAD). Many of these subjects do not report daytime sleepiness, and therefore, are not considered for OSA treatment with continuous…
- Trial name
- RICCADSA (NCT00519597)
- Testing
- ResMed S8 (Auto-CPAP)
- Where
- Sweden
- Volunteers
- 511 people
- Sponsor
- Skaraborg Hospital
Acute Mountain Sickness
The Effect of Continuous Positive Pressure Ventilation on Symptoms of Acute Mountain Sickness
Acute Mountain Sickness (AMS) is a common condition affecting individuals traveling to elevations greater than 2500 meters (8200 feet).
- Trial name
- NCT06145113
- Testing
- Continuous positive airway pressure (CPAP), ResMed AirMini
- Where
- Nepal
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Obstructive Sleep Apnea
Field Usability Study of Eclipse Mask
The study is designed to assess the usability of a novel CPAP human interface compared to a traditional nasal mask. Human subjects will interact with two different CPAP interfaces including a traditional CPAP mask and the 2nd…
- Trial name
- NCT05559047
- Testing
- Eclipse mask
- Where
- 3 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bleep, LLC
Mechanical Ventilation Weaning, Chronic Disease
Phenotype-Guided Weaning in Mechanically Ventilated Patients With Chronic Comorbidities
The goal of this clinical trial is to learn whether a phenotype-guided weaning strategy can help adults with chronic comorbidities be liberated from invasive mechanical ventilation earlier.
- Trial name
- NCT07594418
- Testing
- Phenotype-Guided Weaning Strategy, Standard Care
- Volunteers
- 1,380 people
- Sponsor
- Southeast University, China
Acute Respiratory Failure
Continous Positive Airway Pressure (CPAP) Support for Acute Hypoxemic Respiratory Failure in Burkina Faso
Acute respiratory failure (ARF) is a frequent medical emergency, involving high costs for health organizations and patients who often require intensive care and respiratory assistance.
- Trial name
- NCT06912360
- Testing
- CPAP
- Where
- 4 sites in Burkina Faso
- Volunteers
- 240 people
- Sponsor
- Université NAZI BONI
Heart Failure
Cardiac Rehabilitation and Noninvasive Ventilation in Heart Failure
The study aims to demonstrate the efficacy of NIV continuously in cardiac rehabilitation programs, improvement of exercise tolerance, with consequent reflection in functional capacity and quality of life of this population.
- Trial name
- NCT02811146
- Testing
- Bilevel Positive Pressure Airway, Heart rehabilitation
- Where
- 2 sites in Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Federal de Pernambuco
Obstructive Sleep Apnea
Domiciliary Transcutaneous Electrical Stimulation in Obstructive Sleep Apnoea
The aim of this study is to assess the efficacy of transcutaneous electrical stimulation of the pharyngeal dilator muscles in patients with obstructive sleep apnoea in the community compared to usual care, and follow the patients…
- Trial name
- TESLA-home (NCT03160456)
- Testing
- Transcutaneous electrical stimulation, Continuous positive airway pressure
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Adherence, Treatment, Health Literacy
Sociological Determinants of Positive Airway Pressure Adherence in OSA Patients
Multicentric, prospective, opened study to evaluate the impact of Health Literacy Levels on CPAP withdrawal in Obstructive Sleep Apnea patients within 6 months of inclusion.
- Conditions
- Adherence, Treatment, Health Literacy, Obstructive Sleep Apnea
- Trial name
- SOCIO-SAS (NCT05385302)
- Where
- 2 sites in France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Grenoble
Obstructive Sleep Apnea of Adult, Heart Valve Diseases
Loop Gain in the Reversion of OSA Treated by Either CPAP or Cardiac Valve Replacement
Sleep apnea including obstructive sleep apnea (OSA) and central sleep apnea (CSA), are common in patients with cardiovascular disease.
- Trial name
- NCT03839654
- Testing
- continuous positive airway pressure
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Nanjing Medical University
Obstructive Sleep Apnea
To Study the Impact of CPAP on Gait Parameters in OSA Patients
To study the impact of CPAP therapy on gait in patients with obstructive sleep apnea syndrome.
- Trial name
- OSA_Gait (NCT02061046)
- Testing
- CPAP therapy
- Where
- Switzerland
- Volunteers
- 35 people
- Sponsor
- University Hospital, Geneva
Chronic Cough, OSA
Sham CPAP vs. Straight CPAP for Chronic Cough
Chronic cough is an important clinical problem in primary care and sub-specialty practice. Besides the distress experienced by patients with chronic cough, significant healthcare resources are expended to understand the role of…
- Trial name
- NCT03172130
- Testing
- Straight CPAP
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Krishna M. Sundar
Obesity, Obstructive Sleep Apnoea Syndrome
Study of Eating Behaviour and Sense of Taste Before and After Treatment With Nocturnal Continuous Positive Airway Pressure in Overweight Patients With Obstructive Sleep Apnea Syndrome.
Obstructive sleep apnea (OSA) is characterized by a repeated partial or complete obstruction of the airway that results in a intermittent hypoxia and sleep disturbance.
- Trial name
- GOUSAS (NCT03701737)
- Testing
- questionnaires, wrist actimeter, Blood samples
- Where
- France
- Volunteers
- 94 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Haemodynamic Rebound
Hemodynamic Repercussions of Noninvasive Ventilation
The noninvasive ventilation (NIV) is a method of ventilatory support that does not require artificial airway. Its application is associated with complex hemodynamic repercussions, therefore is important to identify them for…
- Trial name
- NCT02139631
- Testing
- Noninvasive ventilation
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Adherence to CPAP in Obstructive Sleep Apnea
Evaluating Behavioral Treatments to Improve Adherence to CPAP in People With Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is a serious sleep disorder in which a person repeatedly stops breathing or experiences shallow breathing for short periods of time during sleep.
- Trial name
- BREATHE (NCT00939601)
- Testing
- Motivational Enhancement Therapy, Educational Counseling
- Sponsor
- Brown University
Transient Tachypnea of the Newborn
High Flow Nasal Cannula Versus Bubble Nasal CPAP for the Treatment of Transient Tachypnea of the Newborn in Infants ≥ 35 Weeks Gestation
The primary objective is to determine whether High Flow Nasal Cannula (HFNC) is a superior respiratory modality for neonates ≥36 weeks with transient tachypnea of the newborn (TTN) when compared to the standard of care modality…
- Trial name
- NCT01270581
- Testing
- High Flow Nasal Cannula, Bubble Nasal CPAP
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Bronchopulmonary Dysplasia, Nasal High-frequency Oscillatory Ventilation
Nasal High-frequency Oscillatory Ventilation (NHFOV) for Ventilated Newborn Infants With BPD
Invasive ventilation(IV) remains one key cornerstone to reduce neonatal mortality for preterm infants with respiratory distress syndrome(RDS) and/or acute respiratory distress syndrome(ARDS).
- Conditions
- Bronchopulmonary Dysplasia, Nasal High-frequency Oscillatory Ventilation, Nasal Continuous Positive Airway Pressure, Neonate
- Trial name
- NCT04905732
- Testing
- NHFOV, NCPAP
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Obstructive Sleep Apnea (OSA)
Mandibular Advancement Device (MAD) and Continuous Positive Airway Pressure (CPAP) for Treatment of Adult Patients Diagnosed With Moderate Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is a frequent illness related to sleep and breathing with many symptoms and complications. The primary choices of treatment are continuous positive airway pressure (CPAP) and removable appliance for…
- Trial name
- NCT07677332
- Testing
- Mandibular advancement device (MAD), Continuous positive airway pressure (CPAP)
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- University of Copenhagen
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